We propose a method to determine the optimal power of the microwave resonance transition that simultaneously improves the signal-to-noise ratio and reduces line width based on saturation broadening theory and experime...We propose a method to determine the optimal power of the microwave resonance transition that simultaneously improves the signal-to-noise ratio and reduces line width based on saturation broadening theory and experiment. Saturation broadening spectra of the ground state hyperfine transition of trapped 199Hg+ ions are measured and analyzed. The value of the optimal microwave power is obtained by using the proposed method and is verified. Rabi oscillations decay spectra of trapped 199Hg+ ions are observed and the optimal microwave irradiation time for the maximum transition signal intensity is determined. This work will help to improve the short-term frequency stability of the mercury ion microwave frequency standard.展开更多
In the present study, we used a proteomics approach based on a two-dimensional electrophoresis (2-DE) reference map to investigate protein expression in the ovarian tissues of pubertal Swiss-Webster mice subjected t...In the present study, we used a proteomics approach based on a two-dimensional electrophoresis (2-DE) reference map to investigate protein expression in the ovarian tissues of pubertal Swiss-Webster mice subjected to carbon ion radiation (CIR). Among the identified proteins, ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) is associated with the cell cycle[1] and that it influences proliferation in ovarian tissues. We analyzed the expression of UCH-L1 and the proliferation marker proliferation cell nuclear antigen (PCNA) following CIR using immunoblotting and immunofluorescence. The proteomics and biochemical results provide insight into the underlying mechanisms of CIR toxicity in ovarian tissues.展开更多
The mechanism of improving the TID radiation hardened ability of partially depleted silicon-oninsulator(SOI) devices by using the back-gate phosphorus ion implantation technology is studied. The electron traps intro...The mechanism of improving the TID radiation hardened ability of partially depleted silicon-oninsulator(SOI) devices by using the back-gate phosphorus ion implantation technology is studied. The electron traps introduced in Si O2 near back Si O2/Si interface by phosphorus ions implantation can offset positive trapped charges near the back-gate interface. The implanted high concentration phosphorus ions can greatly reduce the back-gate effect of a partially depleted SOI NMOS device, and anti-total-dose radiation ability can reach the level of 1 Mrad(Si) for experimental devices.展开更多
During February 15–16, 2014, the energetic electron spectrogram for four successive inner radiation belt crossing show clearly the electron zebra structures and their time evolution which last for about 17 h. Unfortu...During February 15–16, 2014, the energetic electron spectrogram for four successive inner radiation belt crossing show clearly the electron zebra structures and their time evolution which last for about 17 h. Unfortunately, the time of flight(TOF) in RBSPICE measurement is turned off below 3 RE, and the ion measurement is contaminated by electrons. Thus in this study we studied the differences between the ion and electron zebra stripe structures and their time evolution using simple theory and test particle simulation, combining the electron measurement from RBSIPICE onboard Van Allen Probes. Theoretical analysis predicts that the ion zebra stripe structures should lie at a higher energy range than the corresponding electron zebra stripe structures due to that the directions of gradient B drift and corotation E×B drift are the same for electrons while opposite for ions. Test particle simulation with the dipole magnetic field and Volland-Stern electric field model have shown that the ion and electron zebra stripe structures could be produced by the convection electric field penetrating into the inner magnetosphere in this event, with their time evolution determined by total drift velocity that are different for ions and electrons. The predicted differences between the ion and electron zebra stripe structures are partially verified through observation. The ion zebra stripe structures could have potential influence to the ring current.展开更多
For both primary and metastatic renal cell carcinoma(RCC),treatment with stereotactic body radiotherapy(SBRT)has found its way into clinical practice.Being a non-invasive outpatient procedure,SBRT requires only a few ...For both primary and metastatic renal cell carcinoma(RCC),treatment with stereotactic body radiotherapy(SBRT)has found its way into clinical practice.Being a non-invasive outpatient procedure,SBRT requires only a few visits to the radiation department and may be of interest for the elderly or,in the case of primary RCC,for patients who are not considered surgical candidates due to technical limitations,medical comorbidities,or in the event that the maintenance of kidney function is compromised.In the treatment landscape of oligometastatic RCC,SBRT shows promise in eradicating metastatic disease and delaying the initiation of systemic treatment.Technical advancements in the planning and administration of radiation treatment and improvements in movement management allow irradiating the tumor and/or metastatic lesions with very high doses in few fractions while maximally sparing the surrounding organs at risk,thus minimizing toxicity.In that context,the increasing availability of particle therapy,such as proton beam radiotherapy or carbon ion radiotherapy,could further optimize the delivery of radiation treatment in order to reduce toxicity and improve outcome.展开更多
基金Supported by the National Natural Science Foundation of China under Grant Nos 11074282 and 11474320
文摘We propose a method to determine the optimal power of the microwave resonance transition that simultaneously improves the signal-to-noise ratio and reduces line width based on saturation broadening theory and experiment. Saturation broadening spectra of the ground state hyperfine transition of trapped 199Hg+ ions are measured and analyzed. The value of the optimal microwave power is obtained by using the proposed method and is verified. Rabi oscillations decay spectra of trapped 199Hg+ ions are observed and the optimal microwave irradiation time for the maximum transition signal intensity is determined. This work will help to improve the short-term frequency stability of the mercury ion microwave frequency standard.
基金supported by the Fostering Foundation for the Excellent Ph D.Dissertation of Gansu Agricultural University(2013002)the National High Technology Research and Development Program of China(2013AA102505)the Ministry of Science and Technology National Key R&D project(2016YFC0904600)
文摘In the present study, we used a proteomics approach based on a two-dimensional electrophoresis (2-DE) reference map to investigate protein expression in the ovarian tissues of pubertal Swiss-Webster mice subjected to carbon ion radiation (CIR). Among the identified proteins, ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) is associated with the cell cycle[1] and that it influences proliferation in ovarian tissues. We analyzed the expression of UCH-L1 and the proliferation marker proliferation cell nuclear antigen (PCNA) following CIR using immunoblotting and immunofluorescence. The proteomics and biochemical results provide insight into the underlying mechanisms of CIR toxicity in ovarian tissues.
基金Project supported by the Major Fund for the National Science and Technology Program,China(No.2009ZX02306-04)the Fund of SOI Research and Development Center(No.20106250XXX)
文摘The mechanism of improving the TID radiation hardened ability of partially depleted silicon-oninsulator(SOI) devices by using the back-gate phosphorus ion implantation technology is studied. The electron traps introduced in Si O2 near back Si O2/Si interface by phosphorus ions implantation can offset positive trapped charges near the back-gate interface. The implanted high concentration phosphorus ions can greatly reduce the back-gate effect of a partially depleted SOI NMOS device, and anti-total-dose radiation ability can reach the level of 1 Mrad(Si) for experimental devices.
基金supported by the Major Project of Chinese National Programs for Fundamental Research and Development(Grant No.2012CB825603)the National Natural Science Foundation of China(Grant Nos.41421003&41474148)+1 种基金the Strategic Priority Research Program on Space Science,the Chinese Academy of Sciences(Grant No.XDA04060201)supported by JHU/APL(Subcontract No.937836)to the New Jersey Institute of Technology under NASA Prime(Contract No.NAS5-01072)
文摘During February 15–16, 2014, the energetic electron spectrogram for four successive inner radiation belt crossing show clearly the electron zebra structures and their time evolution which last for about 17 h. Unfortunately, the time of flight(TOF) in RBSPICE measurement is turned off below 3 RE, and the ion measurement is contaminated by electrons. Thus in this study we studied the differences between the ion and electron zebra stripe structures and their time evolution using simple theory and test particle simulation, combining the electron measurement from RBSIPICE onboard Van Allen Probes. Theoretical analysis predicts that the ion zebra stripe structures should lie at a higher energy range than the corresponding electron zebra stripe structures due to that the directions of gradient B drift and corotation E×B drift are the same for electrons while opposite for ions. Test particle simulation with the dipole magnetic field and Volland-Stern electric field model have shown that the ion and electron zebra stripe structures could be produced by the convection electric field penetrating into the inner magnetosphere in this event, with their time evolution determined by total drift velocity that are different for ions and electrons. The predicted differences between the ion and electron zebra stripe structures are partially verified through observation. The ion zebra stripe structures could have potential influence to the ring current.
文摘For both primary and metastatic renal cell carcinoma(RCC),treatment with stereotactic body radiotherapy(SBRT)has found its way into clinical practice.Being a non-invasive outpatient procedure,SBRT requires only a few visits to the radiation department and may be of interest for the elderly or,in the case of primary RCC,for patients who are not considered surgical candidates due to technical limitations,medical comorbidities,or in the event that the maintenance of kidney function is compromised.In the treatment landscape of oligometastatic RCC,SBRT shows promise in eradicating metastatic disease and delaying the initiation of systemic treatment.Technical advancements in the planning and administration of radiation treatment and improvements in movement management allow irradiating the tumor and/or metastatic lesions with very high doses in few fractions while maximally sparing the surrounding organs at risk,thus minimizing toxicity.In that context,the increasing availability of particle therapy,such as proton beam radiotherapy or carbon ion radiotherapy,could further optimize the delivery of radiation treatment in order to reduce toxicity and improve outcome.