mouth occlusion pressure (P<sub>0.1</sub>) rather than inspiratory ventilation （V<sub>1</sub>）and mean inspiratory airflow （（?）） was used for expounding the mechanism of indi-vidual hypox...mouth occlusion pressure (P<sub>0.1</sub>) rather than inspiratory ventilation （V<sub>1</sub>）and mean inspiratory airflow （（?）） was used for expounding the mechanism of indi-vidual hypoxic sensitivity.Eighteen young healthy male subjects participated inthe experiment of progressive isocapnic hypoxia produced by rebreathing method.The results showed that there were significantly linear relationship （P【0.01） be-tween V<sub>1</sub> and P<sub>0.1</sub>,as well as （?） and P<sub>0.1</sub> during the hypoxic loading of twoend-tidal carbon dioxide pressure (P<sub>ETCO<sub>2</sub></sub> levels,4.3 and 5.9kPa.Ventilation in-creased with progressive hypoxia.Therefore,they all represent the useful indexesof inspiratory drive.P<sub>0.1</sub> is more sensitive than V<sub>1</sub> and （?） because it isindependent of pulmonary mechanics.展开更多
文摘mouth occlusion pressure (P<sub>0.1</sub>) rather than inspiratory ventilation （V<sub>1</sub>）and mean inspiratory airflow （（?）） was used for expounding the mechanism of indi-vidual hypoxic sensitivity.Eighteen young healthy male subjects participated inthe experiment of progressive isocapnic hypoxia produced by rebreathing method.The results showed that there were significantly linear relationship （P【0.01） be-tween V<sub>1</sub> and P<sub>0.1</sub>,as well as （?） and P<sub>0.1</sub> during the hypoxic loading of twoend-tidal carbon dioxide pressure (P<sub>ETCO<sub>2</sub></sub> levels,4.3 and 5.9kPa.Ventilation in-creased with progressive hypoxia.Therefore,they all represent the useful indexesof inspiratory drive.P<sub>0.1</sub> is more sensitive than V<sub>1</sub> and （?） because it isindependent of pulmonary mechanics.
