FPSblo:A Blockchain Network Transmission Model Utilizing Farthest Point Sampling

Peer-to-peer(P2P)overlay networks provide message transmission capabilities for blockchain systems.Improving data transmission efficiency in P2P networks can greatly enhance the performance of blockchain systems.However,traditional blockchain P2P networks face a common challenge where there is often a mismatch between the upper-layer traffic requirements and the underlying physical network topology.This mismatch results in redundant data transmission and inefficient routing,severely constraining the scalability of blockchain systems.To address these pressing issues,we propose FPSblo,an efficient transmission method for blockchain networks.Our inspiration for FPSblo stems from the Farthest Point Sampling(FPS)algorithm,a well-established technique widely utilized in point cloud image processing.In this work,we analogize blockchain nodes to points in a point cloud image and select a representative set of nodes to prioritize message forwarding so that messages reach the network edge quickly and are evenly distributed.Moreover,we compare our model with the Kadcast transmission model,which is a classic improvement model for blockchain P2P transmission networks,the experimental findings show that the FPSblo model reduces 34.8%of transmission redundancy and reduces the overload rate by 37.6%.By conducting experimental analysis,the FPS-BT model enhances the transmission capabilities of the P2P network in blockchain.

一类带有p-Laplacian算子的分数阶积分边值问题正解的存在性

研究了一类带有p-Laplacian算子的分数阶积分边值问题正解的存在性,利用混合单调算子的不动点定理,获得了该边值问题唯一正解存在的充分条件,并给出两个具体的例子作为应用.

Dual-functional poly(2-methyl-2-oxazoline)/poly(2-(dimethylamine)ethyl methacrylate)mixed brushes with switchable protein adsorption and antibacterial properties

Herein,binary mixed brushes consisting of poly(2-methyl-2-oxazoline)(PMOXA)and poly(2-(dimethylamine)ethyl methacrylate)(PDMAEMA)with different chain lengths were fabricated by successive grafting of NH_(2)-terminated PMOXA and SH-terminated PDMAEMA onto polydopamine-anchored substrates.The mixed-brush coating was characterized by variable-angle spectroscopic ellipsometry,X-ray photoelectron spectroscopy,Fourier transform infrared spectroscopy,zeta potential measurements,water contact angle,and atomic force microscopy.The mixed brushes showed tunable surface charge,wettability,and surface roughness,depending on the degree of PDMAEMA swelling under varying pH and ionic strength(Ⅰ).Then the adsorption behaviors of pepsin,bovine serum albumin(BSA),γ-globulin,and lysozyme,four very different proteins with regard to isoelectric point,on the mixed brushes coating were studied by using fluorescence microscopy and surface plasmon resonance.When the chain length of PDMAEMA was about twice as long as PMOXA,the mixed brushes not only had high adsorption capacity for pepsin,BSA,and y-globulin but also had a desorption efficiency of 86.9%,87.1%,and 93.5%,respectively.It is explained that electrostatic attraction between the protonated PDMAEMA and positively charged acidic proteins(pepsin and BSA,whose isoelectric points were below the pK_(a) of PDMAEMA)would drive the intensive adsorption(at pH 3,I=10^(-3)mol·L^(-1)for pepsin,and pH 5,I=10^(-5)mol·L^(-1)for BSA),while desorption was dominated by the hydrophilic PMOXA when PDMAEMA was shrinking(at pH 7,I=10^(-1)mol·L^(-1)for pepsin,and pH 9,I=10^(-1)mol·L^(-1)for BSA).Furthermore,the isoelectric precipitation led to the adsorption of neutral protein(γ-globulin,whose isoelectric point was near the pK_a of PDMAEMA)at pH 7,I=10^(-5)mol·L^(-1),while electrostatic repulsion and antifouling PMOXA triggered the desorption of y-globulin at pH 3,I-10^(-1)mol·L^(-1).However,alkaline protein(lysozyme,whose isoelectric point was higher than the pK_(a) of PDMAEMA)exhibited slight adsorption on PMOXA/PDMAEMA mixed brushes under test conditions,regardless of whether PMOXA or PDMAEMA occupied the outermost layer.The antibacterial property of the mixed brushes against Escherichia coli was investigated.PMOXA/PDMAEMA mixed brushes showed significant bactericidal activity at pH 3,I=10^(-3)mol·L^(-1),while the rinse of pH 9,I=10^(-1)mol·L^(-1)solution could remove most of the residual bacteria.This work not only enables controlled adsorption of proteins with different isoelectric points but also ensures that the surface of the coating is minimized from bacterial contamination.

基于MPPT光伏系统SIC-FT控制算法的研究

由于太阳电池输出特性具有非线性特征,最大功率点追踪(MPPT)算法已应用于各大型或小微型光伏发电系统中。以MPPT算法中的传统定步长扰动观察法(P&O)为研究基础,针对该算法的追踪速度与稳态抑制难以平衡的问题,提出一种基于P&O的稳态识别控制与快速追踪相结合的MPPT算法(SIC-FT算法),同时提出一种评价MPPT算法性能的评价体系。通过在Matlab2022a/Simulink平台上搭建模型,对提出的算法以及其他基于P&O改进的算法,应用该文提出的评价体系进行仿真对比。结果显示,所提算法整体上优于仿真的其他同类算法。

具p-Laplacin算子的Caputo型分数阶微分方程边值问题的解

主要运用Schauder不动点定理,研究了一类具p-Laplacin算子的Caputo型分数阶微分方程的边值问题,得到了解决这类问题解的存在性的充分条件,并给出实例加以验证.

The Magnetic Longitudinal (P-) Wave’s Propagation and Energy Models Underlying the Mechanisms of Its Capacity to Absorb Free Energy

The longitudinal wave term within Faraday’s law of electromagnetic induction (Faraday’s law) underwent recovery to ensure its suitability for theoretical derivation of the equation governing longitudinal electromagnetic (LEM) waves. The revised Maxwell’s equations include the crucial parameters being the attenuation time constants of magnetic vortex potential and electric vortex potential generated by external electromagnetic field within the propagation medium. Specific expressions for them are obtained through theoretical analysis. Subsequently, a model for propagating magnetic P-wave generated by the superposition of a left-handed photo and a right-handed photon in a vacuum is formulated based on reevaluated total current law and revised Faraday’s law, covering wave equations, energy equation, as well as propagation mode involving mutual induction and conversion between scalar magnetic field and vortex electric field. Furthermore, through theoretical derivations centered around magnetic P-wave, evidence was presented regarding its ability to absorb huge free energy through the entangled interaction between zero-point vacuum energy field and the torsion field produced by the vortex electric field.

The Isoelectric Point and the Points of Zero Charge of Fe-Al-Mg Hydrotalcite-like Compounds

The relation of the isoelectric point (IEP) and the point of zero net charge (PZNC) of the hydrotalcite-like compounds was discussed. It was found that the IEP does not equal to the PZNC and the IEP is higher than the PZNC. The structural positive charges existing in the HTlc, which cause the difference between the IEP and the PZNC. The effects of the structural positive charges of the HTlc on its IEP and PZNC are the same as the specific adsorption of metal cations.

Study on Isoelectric Point of Magnesium Aluminum Hydroxide

Yoon's equation which predicted point of zero charge of complex oxide should predict the zero point of net charge (ZPNC) of mixture of variable and permanent charge rather than the point of zero charge (PZC) of the variable charge component. The calculated values with modified Yoon's equation agreed with the experimental values.

H-point计算分光光度法研究及其在复方盐酸丁卡因注射液中的应用

介绍几种Ｈ－ｐｏｉｎｔ法，并与常见的计算分光光度法进行了比较。将Ｈ－ｐｏｉｎｔ法用于复方盐酸丁卡因注射液测定的数据处理，表明Ｈ－ｐｏｉｎｔ法有效地消除干扰，有较高的精密度和准确度。盐酸丁卡因回收率为：Ｈ－ｐｏｉｎｔ法１０１．０％，ＲＳＤ为２．７％（ｎ＝７），Ｋ系数Ｈ－ｐｏｉｎｔ法９９．１％，ＲＳＤ为１．８％（ｎ＝７），三波长Ｈ－ｐｏｉｎｔ法９９．６％，ＲＳＤ为１．４％（ｎ＝７）。

局部阴影下基于GWO-P&O混合算法的光伏最大功率点跟踪

针对局部遮阴环境下传统灰狼优化(Gray wolf optimization,GWO)算法在跟踪最大功率点时P-U特性曲线出现多峰值、后期收敛速度慢、稳态精度低等问题,结合灰狼优化算法和扰动观察法(Perturbation and observation,P&O)各自的优势,提出了基于GWO-P&O的混合优化最大功率点跟踪(Maximum power point tracking,MPPT)算法。首先,采用灰狼优化算法逐渐向光伏的全局最大功率点靠近。其次,在灰狼优化算法收敛后期引入P&O法,既保持了灰狼优化算法较高的稳态精度,又能以较快速度寻找到局部最大功率点。最后,在不同环境工况下,将所提出的GWO-P&O方法与传统GWO算法进行对比。结果表明,改进的GWO-P&O算法在保证良好稳态性能的同时,一定程度上提高了GWO算法后期跟踪最大功率时的收敛速度。

基于ESO和分数阶PID的改进P&O控制策略

为了提高光伏电池转换效率、降低能量损失,有必要研究最大功率点跟踪(maximum power point tracking,MPPT)方法。针对传统扰动观察法(perturbation observation method,P&O)存在无法兼顾跟踪速度与稳态精度、在光照度发生较大变化时会产生误判现象的问题,文中提出一种能适应环境变化的变步长P&O控制策略。首先,利用光伏电池刚启动时类似恒流源的特性获取当前光照度下的短路电流,通过固定电流法推导出最大功率点(maximum power point,MPP)的参考电压;其次,当光照度突变时,提出功率修正方法,并给出突变时的变步长调整策略;最后,设计基于线性扩张状态观测器(linear extended state observer,LESO)的分数阶比例积分微分(fractional order proportion integration differentiation,FOPID)控制器,可以对算法输出的参考电压进一步进行跟踪补偿。仿真结果表明,所提控制策略可以提高稳态精度和跟踪速度,有效提高光伏电池的输出功率。

具有p-Laplacian算子的分数阶微分耦合系统边值问题的正解

本文考虑一类具有p-Laplacian算子和无穷多点边界条件的分数阶微分耦合系统,利用Avery-Peterson不动点定理得到该系统至少三个正解的存在性,扩展了已有的结果.

一类含p-Laplacian算子的分数阶时滞微分方程无穷多点边值问题的正解

主要研究一类含有p-Laplacian算子和时滞的分数阶微分方程的无穷多点边值问题.先构造Green函数并分析其性质,再利用p-Laplacian算子的性质和Banach压缩映射原理,得到这类边值问题正解存在唯一的一些新结果.

带有p-Laplacian算子的分数阶积分-微分方程边值问题正解的存在性

研究了带有p-Laplacian算子以及变Riemann-Liouville分数阶积分的分数阶积分-微分方程的边值问题,利用锥上的不动点定理,得到了该边值问题正解的存在性结果.

Expressions of apoptosis-related proteins in rats with focal cerebral ischemia after Angong Niuhuang sticker point application

In this study, we extracted and purified components in the Angong Niuhuang pill. Then we applied transdermal enhancers to Angong Niuhuang stickers by modern technology. The Angong Niuhuang sticker includes extracts from curcuma, berberine hydrochloride, baicalin, geniposide, borneol, and musk. Angong Niuhuang stickers at different point application doses （1.35, 2.7, and 5.4 g/kg） were administered to Dazhui （DU14）, Qihai （RN6） and Mingmen （DU4）. Rats in the different dose point application and acupuncture groups were continuously administered for 7 days. Then a middle cerebral artery occlusion model was prepared for simulating human cerebral ischemia. Twelve hours later, expressions of Bcl-2, Bax and p53 protein in hippocampal CA1 were detected with immunohistochemistry. The expression level of Bcl-2, an anti-apoptotic protein, significantly increased in the high-, medium- and low-dose point application groups and the acupuncture group, while the expression of the pro-apoptotic proteins, Bax and p53, significantly decreased compared with the middle cerebral artery occlusion rats; and the Bcl-2/Bax ratio was significantly increased. The difference was noticeable for the high-dose point application group, which showed statistical difference compared with the low-dose point application group and the acupuncture group. Our experimental findings indicate that point application with Angong Niuhuang stickers promotes the expression of Bcl-2, and inhibits the expressions of Bax and p53 in the hippocampal CA1 area of rats after focal cerebral ischemia. Thus, point application of Angong Niuhang stickers protects brain tissues from cerebral ischemia.

Electroacupuncture at He-Mu points reduces P2X_4 receptor expression in visceral hypersensitivity

Electroacupuncture at Shangjuxu （ST37） and Tianshu （ST25） was reported to improve visceral hypersensitivity in rats, Colorectal distension was utilized to generate a rat model of chronic visceral hypersensitivity in irritable bowel syndrome, Results showed that abdominal withdrawal reflex scores noticeably increased after model establishment. Simultaneously, P2X4 receptor immunore- activity significantly increased in the colon and spinal cord. Electroacupuncture and pinaverium bromide therapy both markedly decreased abdominal withdrawal reflex scores in rats with visceral hypersensitivity, and significantly decreased P2X4 receptor immunoreactivity in the colon and spinal cord. These data suggest that electroacupuncture treatment can improve visceral hypersensitivity in rats with irritable bowel syndrome by diminishing P2X4 receptor immunoreactivity in the colon and spinal cord,

DELETIONS AND POINT MUTATIONS OF p16,p15 GENE IN PRIMARY TUMORS AND TUMOR CELL LINES

Aberrations of chromosome 9 p21 22 are involved in the genesis of many forms of cancer.The gene p16 and p15 have been assigned to this region.Both p16 and p15 are an inhibitor of cyclin D cdk4,cyclin D cdk6 complex and have been implicated in a wide variety of cancer types,including the germline of patients with familial melanoma.In order to investigate and compare the status of p16,p15 gene in primary tumors and cell lines,we examined 357 primary tumors and 29 cell lines derived from diverse tumor types.In addition to analysis of these primary tumors and cell lines,blood specimens from 91 patients either with sporadic multiple cancers or from cancer prone families were also analyzed.The data showed the following:1)Homozygous deletions of p16,p15 were comparatively rare and far less common than previously reported,although hemizygous deletions were observed in a significant fraction of many tumor types;2)the incidence of p16,p15 deletions(either homozygous deletions or heterozygous deletions)varied significantly among different tumor types;3)most deletions involved in both p16 and p15 genes;4)sequence variations in the coding sequence of p16,p15 were comparatively rare among these tumor types,though mutations and polymorphisms were identified;5)some tumors which showed LOH at 9p,containing p16 and p15 gene,did not show deletions or point mutations in the p16,p15 gene.6)In a subset of retinoblastoma and osteosarcoma where no Rb gene mutations were present a significant fraction was found to contain p16,p15 gene deletions.

一类带p-Laplacian算子的分数阶微分方程边值问题解的存在性

该文运用Leray-Schauder非线性择抉和Krasnosel skiis不动点定理,讨论了一类在一致分数阶导数定义下含p-Laplacian算子的分数阶微分方程边值问题∅p(Tαx(t))′=f(t,x(t)),0≤t≤1,x(0)=Tαx(0)=0,x(1)=μ∫η0x(t)d t解的存在性.其中,1<α≤2,μ≥0,0<η≤1,∅p(s)=|s|p-2 s,(∅p)-1=∅q,p>1,p^(-1)+q^(-1)=1,Tα是一致分数阶导数,f:[0,1]×ℝ→ℝ是给定的连续函数.

带p(t)-Laplace算子的分数阶Langevin方程参数型反周期边值问题解的存在性

利用Schaefer不动点定理,讨论一类带有p(t)-Laplace算子的分数阶Langevin方程参数型反周期边值问题,通过给出非线性项合理的假设条件得到了其解的存在性结果,并举例说明主要结果的应用.