The condensation of aromatic aldehydes with isopropylidene malonate or 5,5-dimethyl-1,3-cyclohexanedione is carried out by DMF as solvent without catalyst.
Introduction 5-Monosubstituted isopropylidene malonates arc important synthetic organic intermediates. Since isopropylidene malonate has a stronger acidity （pK;=4.57）, its direct alkylation with alkyl halides usuall...Introduction 5-Monosubstituted isopropylidene malonates arc important synthetic organic intermediates. Since isopropylidene malonate has a stronger acidity （pK;=4.57）, its direct alkylation with alkyl halides usually gives 5,5-disubstitutcd isopropylidene malonates.展开更多
文摘The condensation of aromatic aldehydes with isopropylidene malonate or 5,5-dimethyl-1,3-cyclohexanedione is carried out by DMF as solvent without catalyst.
基金Supported by the National Natural Science Foundation of Chinathe Basic Research Foundation of Zhejian Educational Commission.
文摘Introduction 5-Monosubstituted isopropylidene malonates arc important synthetic organic intermediates. Since isopropylidene malonate has a stronger acidity （pK;=4.57）, its direct alkylation with alkyl halides usually gives 5,5-disubstitutcd isopropylidene malonates.
