In Japan when urban infrastructures need to be constructed, the difficulty of utilizing the ground or shallow strata will lead to a more frequent use of the deep strata. The common construction methods are open-cut, p...In Japan when urban infrastructures need to be constructed, the difficulty of utilizing the ground or shallow strata will lead to a more frequent use of the deep strata. The common construction methods are open-cut, pipe jacking, and shield methods. In recent years, a new pipe jacking method has been established that can be adapted to 20 m below the ground or more. Using this method, the drivage machine and the jacking pipe continue to move an underground until the completion of the driving. Therefore an over-cutting area (so-called tail-void) must be formed to lower the friction between the ground and the pipe. The tail-void is filled with lubrications. However, because the stress release from the ground continues to advance when the tail-void is formed, hence there are some challenges required to cope with the stability of the surrounding ground. In order to utilize the pipe jacking method in the deeper strata layers, the theory, analysis and installation of tail-void have to be systemized, and such systematic data must be stored. Therefore, the conditions of tail-void in the deep pipe jacking method are discussed using numerical analyses.展开更多
Tunnels in an urban area, in many cases, are constructed in soft ground which contains underground water, near existing facilities and structures. Structural stability for the tunnel and also the nearby structures and...Tunnels in an urban area, in many cases, are constructed in soft ground which contains underground water, near existing facilities and structures. Structural stability for the tunnel and also the nearby structures and facilities is vital in this kind of work. Slurry pipe jacking was firmly established as a special method for the non-disruptive construction of underground pipelines of sewage systems. This method utilizes mud slurry that is formed around the pipes in order to stabilize the surrounding soil. In the pipe roof method the tubing elements that are constructed by slurry pipe jacking are near each other longitudinally, and create a rigid and stable lining before the excavation of the main tunnel. This paper discusses 'the application of a slurry pipe jacking system on 'the pipe roof method by means of numerical analysis. Because of the rigid behavior of the lining, the results show little subsidence, making this method a reliable method of constructing large tunnels with small cover in an urban area.展开更多
Jack-up units are extensively playing a successful role in drilling engineering around the world, and their safety and efficiency take more and more attraction in both research and engineering practice. An accurate pr...Jack-up units are extensively playing a successful role in drilling engineering around the world, and their safety and efficiency take more and more attraction in both research and engineering practice. An accurate prediction of the spudcan penetration depth is quite instrumental in deciding on whether a jack-up unit is feasible to operate at the site. The prediction of a too large penetration depth may lead to the hesitation or even rejection of a site due to potential difficulties in the subsequent extraction process; the same is true of a too small depth prediction due to the problem of possible instability during operation. However, a deviation between predictive results and final field data usually exists, especially when a strong-over-soft soil is included in the strata. The ultimate decision sometimes to a great extent depends on the practical experience, not the predictive results given by the guideline. It is somewhat risky, but no choice. Therefore, a feasible predictive method for the spudcan penetration depth, especially in strata with strong-over-soft soil profile, is urgently needed by the jack-up industry. In view of this, a comprehensive investigation on methods of predicting spudcan penetration is executed. For types of different soil profiles, predictive methods for spudcan penetration depth are proposed, and the corresponding experiment is also conducted to validate these methods. In addition, to further verify the feasibility of the proposed methods, a practical engineering case encountered in the South China Sea is also presented, and the corresponding numerical and experimental results are also presented and discussed.展开更多
In this paper, the jacket platform is simulated by a non-uniform cantilever beam subjected to axial force. Based on the Hamilton theory, the equation of bending motion is developed and solved by the classical Ritz met...In this paper, the jacket platform is simulated by a non-uniform cantilever beam subjected to axial force. Based on the Hamilton theory, the equation of bending motion is developed and solved by the classical Ritz method combined with the pseudo-excitation method for random responses with non-classical damping. Usually, random responses of this continuous structure are obtained by orthogonality of modes, and some normal modes of the structure are needed, causing inconvenience for the analysis of the non-uniform beam whose normal modes are not easy to be obtained. However, if the pseudo-excitation method is extended to calculate random responses by combining it with the classical Ritz method, the responses of a non-uniform beam, such as auto-PSD function, cross-PSD and higher spectral moments, can be solved directly avoiding the calculation of normal modes. The numerical results show that the present method is effective and useful in aseismic design of platforms.展开更多
Condensed and hydrolysable tannins are non-toxic natural polyphenols that are a commercial commodity industrialized for tanning hides to obtain leather and for a growing number of other industrial applications mainly ...Condensed and hydrolysable tannins are non-toxic natural polyphenols that are a commercial commodity industrialized for tanning hides to obtain leather and for a growing number of other industrial applications mainly to substitute petroleum-based products.They are a definite class of sustainable materials of the forestry industry.They have been in operation for hundreds of years to manufacture leather and now for a growing number of applications in a variety of other industries,such as wood adhesives,metal coating,pharmaceutical/medical applications and several others.This review presents the main sources,either already or potentially commercial of this forestry by-materials,their industrial and laboratory extraction systems,their systems of analysis with their advantages and drawbacks,be these methods so simple to even appear primitive but nonetheless of proven effectiveness,or very modern and instrumental.It constitutes a basic but essential summary of what is necessary to know of these sustainable materials.In doing so,the review highlights some of the main challenges that remain to be addressed to deliver the quality and economics of tannin supply necessary to fulfill the industrial production requirements for some materials-based uses.展开更多
In this paper a simplified computation method of natural frequency of jacket platforms is given. Shear, bending and rotary inertia effects are considered in the equation, while the jacket shape, rotary inertia and cen...In this paper a simplified computation method of natural frequency of jacket platforms is given. Shear, bending and rotary inertia effects are considered in the equation, while the jacket shape, rotary inertia and centralized mass of the platform top are all determined by using a coefficient-revising method.展开更多
The purpose of this study was to examine the burnout levels of research assistants in Ondokuz Mayis University and to examine the results of multiple linear regression model based on the results obtained from Maslach ...The purpose of this study was to examine the burnout levels of research assistants in Ondokuz Mayis University and to examine the results of multiple linear regression model based on the results obtained from Maslach Burnout Scale with Jackknife Method in terms of validity and generalizability. To do this, a questionnaire was given to 11 research assistants working at Ondokuz Mayis University and the burnout scores of this questionnaire were taken as the dependent variable of the multiple linear regression model. The variable of burnout was explained with the variables of age, weekly hours of classes taught, monthly average credit card debt, numbers of published articles and reports, gender, marital status, number of children and the departments of the research assistants. Dummy variables were assigned to the variables of gender, marital status, number of children and the departments of the research assistants and thus, they were made quantitative. The significance of the model as a result of multiple linear regressions was examined through backward elimination method. After this, for the five explanatory variables which influenced the variable of burnout, standardized model coefficients and coefficients of determination, and 95% confidence intervals of these values were estimated through Jackknife Method and the generalizability of the parameter estimation results of these variables on population was researched.展开更多
The technology of drilling tests makes it possible to obtain the strength parameter of rock accurately in situ. In this paper, a new rock cutting analysis model that considers the influence of the rock crushing zone(R...The technology of drilling tests makes it possible to obtain the strength parameter of rock accurately in situ. In this paper, a new rock cutting analysis model that considers the influence of the rock crushing zone(RCZ) is built. The formula for an ultimate cutting force is established based on the limit equilibrium principle. The relationship between digital drilling parameters(DDP) and the c-φ parameter(DDP-cφ formula, where c refers to the cohesion and φ refers to the internal friction angle) is derived, and the response of drilling parameters and cutting ratio to the strength parameters is analyzed. The drillingbased measuring method for the c-φ parameter of rock is constructed. The laboratory verification test is then completed, and the difference in results between the drilling test and the compression test is less than 6%. On this basis, in-situ rock drilling tests in a traffic tunnel and a coal mine roadway are carried out, and the strength parameters of the surrounding rock are effectively tested. The average difference ratio of the results is less than 11%, which verifies the effectiveness of the proposed method for obtaining the strength parameters based on digital drilling. This study provides methodological support for field testing of rock strength parameters.展开更多
In this study,the structural characters,antioxidant activities and bile acid-binding ability of sea buckthorn polysaccharides(HRPs)obtained by the commonly used hot water(HRP-W),pressurized hot water(HRP-H),ultrasonic...In this study,the structural characters,antioxidant activities and bile acid-binding ability of sea buckthorn polysaccharides(HRPs)obtained by the commonly used hot water(HRP-W),pressurized hot water(HRP-H),ultrasonic(HRP-U),acid(HRP-C)and alkali(HRP-A)assisted extraction methods were investigated.The results demonstrated that extraction methods had significant effects on extraction yield,monosaccharide composition,molecular weight,particle size,triple-helical structure,and surface morphology of HRPs except for the major linkage bands.Thermogravimetric analysis showed that HRP-U with filamentous reticular microstructure exhibited better thermal stability.The HRP-A with the lowest molecular weight and highest arabinose content possessed the best antioxidant activities.Moreover,the rheological analysis indicated that HRPs with higher galacturonic acid content and molecular weight showed higher viscosity and stronger crosslinking network(HRP-C,HRP-W and HRP-U),which exhibited stronger bile acid binding capacity.The present findings provide scientific evidence in the preparation technology of sea buckthorn polysaccharides with good antioxidant and bile acid binding capacity which are related to the structure affected by the extraction methods.展开更多
Offshore platforms are susceptible to structural damage due to prolonged exposure to random loads,such as wind,waves,and currents.This is particularly true for platforms that have been in service for an extended perio...Offshore platforms are susceptible to structural damage due to prolonged exposure to random loads,such as wind,waves,and currents.This is particularly true for platforms that have been in service for an extended period.Identifying the modal parameters of offshore platforms is crucial for damage diagno sis,as it serves as a prerequisite and foundation for the process.Therefore,it holds great significance to prioritize the identification of these parameters.Aiming at the shortcomings of the traditional Fast Bayesian Fast Fourier Transform(FBFFT) method,this paper proposes a modal parameter identification method based on Automatic Frequency Domain Decomposition(AFDD) and optimized FBFFT.By introducing the AFDD method and Powell optimization algorithm,this method can automatically identify the initial value of natural frequency and solve the objective function efficiently and simply.In order to verify the feasibility and effectiveness of the proposed method,it is used to identify the modal parameters of the IASC-ASCE benchmark model and the j acket platform structure model,and the Most Probable Value(MPV) of the modal parameters and their respective posterior uncertainties are successfully identified.The identification results of the IASC-ASCE benc hmark model are compared with the identification re sults of the MODE-ID method,which verifies the effectivene ss and accuracy of the proposed method for identifying modal parameters.It provides a simple and feasible method for quantifying the influence of uncertain factors such as environmental parameters on the identification results,and also provide s a reference for modal parameter identification of other large structures.展开更多
The material point method(MPM)has been gaining increasing popularity as an appropriate approach to the solution of coupled hydro-mechanical problems involving large deformation.In this paper,we survey the current stat...The material point method(MPM)has been gaining increasing popularity as an appropriate approach to the solution of coupled hydro-mechanical problems involving large deformation.In this paper,we survey the current state-of-the-art in the MPM simulation of hydro-mechanical behaviour in two-phase porous geomaterials.The review covers the recent advances and developments in the MPM and their extensions to capture the coupled hydro-mechanical problems involving large deformations.The focus of this review is aiming at providing a clear picture of what has or has not been developed or implemented for simulating two-phase coupled large deformation problems,which will provide some direct reference for both practitioners and researchers.展开更多
In this paper a nonlinear response of a fixed offshore platform under the combined forces of waves, wind and sea currents is presented. Wave force acting on the elements is calculated using Morison equation. Hydrodyna...In this paper a nonlinear response of a fixed offshore platform under the combined forces of waves, wind and sea currents is presented. Wave force acting on the elements is calculated using Morison equation. Hydrodynamic loads on horizontal and vertical tubular members and the dynamic response of offshore fixed platform coupled with distribution of displacement, axial force, and bending moment along the base of the platform for regular and severe cases have been investigated. The structure must be able maintain production in a one-year wave return period condition and also to be able to continue with one hundred-year storm return period. The results of this study show that bending moment values with a one-year wave return period condition for the base platform and junction of platform to deck are 70 percent and 59 percent, respectively more than bending moment with a one-year wave return period. The direction of wave and wind hit has significant effects on the shift platform response, also nonlinear response is important for the safe design and operation of offshore structures.展开更多
Gastric cancer(GC), the fifth most common cancer globally, remains the leading cause of cancer deaths worldwide. Inflammation-induced tumorigenesis is the predominant process in GC development;therefore, systematic re...Gastric cancer(GC), the fifth most common cancer globally, remains the leading cause of cancer deaths worldwide. Inflammation-induced tumorigenesis is the predominant process in GC development;therefore, systematic research in this area should improve understanding of the biological mechanisms that initiate GC development and promote cancer hallmarks. Here, we summarize biological knowledge regarding gastric inflammation-induced tumorigenesis, and characterize the multi-omics data and systems biology methods for investigating GC development. Of note, we highlight pioneering studies in multi-omics data and state-of-the-art network-based algorithms used for dissecting the features of gastric inflammation-induced tumorigenesis, and we propose translational applications in early GC warning biomarkers and precise treatment strategies. This review offers integrative insights for GC research, with the goal of paving the way to novel paradigms for GC precision oncology and prevention.展开更多
Porous materials present significant advantages for absorbing radioactive isotopes in nuclear waste streams.To improve absorption efficiency in nuclear waste treatment,a thorough understanding of the diffusion-advecti...Porous materials present significant advantages for absorbing radioactive isotopes in nuclear waste streams.To improve absorption efficiency in nuclear waste treatment,a thorough understanding of the diffusion-advection process within porous structures is essential for material design.In this study,we present advancements in the volumetric lattice Boltzmann method(VLBM)for modeling and simulating pore-scale diffusion-advection of radioactive isotopes within geopolymer porous structures.These structures are created using the phase field method(PFM)to precisely control pore architectures.In our VLBM approach,we introduce a concentration field of an isotope seamlessly coupled with the velocity field and solve it by the time evolution of its particle population function.To address the computational intensity inherent in the coupled lattice Boltzmann equations for velocity and concentration fields,we implement graphics processing unit(GPU)parallelization.Validation of the developed model involves examining the flow and diffusion fields in porous structures.Remarkably,good agreement is observed for both the velocity field from VLBM and multiphysics object-oriented simulation environment(MOOSE),and the concentration field from VLBM and the finite difference method(FDM).Furthermore,we investigate the effects of background flow,species diffusivity,and porosity on the diffusion-advection behavior by varying the background flow velocity,diffusion coefficient,and pore volume fraction,respectively.Notably,all three parameters exert an influence on the diffusion-advection process.Increased background flow and diffusivity markedly accelerate the process due to increased advection intensity and enhanced diffusion capability,respectively.Conversely,increasing the porosity has a less significant effect,causing a slight slowdown of the diffusion-advection process due to the expanded pore volume.This comprehensive parametric study provides valuable insights into the kinetics of isotope uptake in porous structures,facilitating the development of porous materials for nuclear waste treatment applications.展开更多
In the existing landslide susceptibility prediction(LSP)models,the influences of random errors in landslide conditioning factors on LSP are not considered,instead the original conditioning factors are directly taken a...In the existing landslide susceptibility prediction(LSP)models,the influences of random errors in landslide conditioning factors on LSP are not considered,instead the original conditioning factors are directly taken as the model inputs,which brings uncertainties to LSP results.This study aims to reveal the influence rules of the different proportional random errors in conditioning factors on the LSP un-certainties,and further explore a method which can effectively reduce the random errors in conditioning factors.The original conditioning factors are firstly used to construct original factors-based LSP models,and then different random errors of 5%,10%,15% and 20%are added to these original factors for con-structing relevant errors-based LSP models.Secondly,low-pass filter-based LSP models are constructed by eliminating the random errors using low-pass filter method.Thirdly,the Ruijin County of China with 370 landslides and 16 conditioning factors are used as study case.Three typical machine learning models,i.e.multilayer perceptron(MLP),support vector machine(SVM)and random forest(RF),are selected as LSP models.Finally,the LSP uncertainties are discussed and results show that:(1)The low-pass filter can effectively reduce the random errors in conditioning factors to decrease the LSP uncertainties.(2)With the proportions of random errors increasing from 5%to 20%,the LSP uncertainty increases continuously.(3)The original factors-based models are feasible for LSP in the absence of more accurate conditioning factors.(4)The influence degrees of two uncertainty issues,machine learning models and different proportions of random errors,on the LSP modeling are large and basically the same.(5)The Shapley values effectively explain the internal mechanism of machine learning model predicting landslide sus-ceptibility.In conclusion,greater proportion of random errors in conditioning factors results in higher LSP uncertainty,and low-pass filter can effectively reduce these random errors.展开更多
文摘In Japan when urban infrastructures need to be constructed, the difficulty of utilizing the ground or shallow strata will lead to a more frequent use of the deep strata. The common construction methods are open-cut, pipe jacking, and shield methods. In recent years, a new pipe jacking method has been established that can be adapted to 20 m below the ground or more. Using this method, the drivage machine and the jacking pipe continue to move an underground until the completion of the driving. Therefore an over-cutting area (so-called tail-void) must be formed to lower the friction between the ground and the pipe. The tail-void is filled with lubrications. However, because the stress release from the ground continues to advance when the tail-void is formed, hence there are some challenges required to cope with the stability of the surrounding ground. In order to utilize the pipe jacking method in the deeper strata layers, the theory, analysis and installation of tail-void have to be systemized, and such systematic data must be stored. Therefore, the conditions of tail-void in the deep pipe jacking method are discussed using numerical analyses.
文摘Tunnels in an urban area, in many cases, are constructed in soft ground which contains underground water, near existing facilities and structures. Structural stability for the tunnel and also the nearby structures and facilities is vital in this kind of work. Slurry pipe jacking was firmly established as a special method for the non-disruptive construction of underground pipelines of sewage systems. This method utilizes mud slurry that is formed around the pipes in order to stabilize the surrounding soil. In the pipe roof method the tubing elements that are constructed by slurry pipe jacking are near each other longitudinally, and create a rigid and stable lining before the excavation of the main tunnel. This paper discusses 'the application of a slurry pipe jacking system on 'the pipe roof method by means of numerical analysis. Because of the rigid behavior of the lining, the results show little subsidence, making this method a reliable method of constructing large tunnels with small cover in an urban area.
基金supported by the National High Technology Research and Development Program of China(863 Program,Grant No.2008AA092701-3)
文摘Jack-up units are extensively playing a successful role in drilling engineering around the world, and their safety and efficiency take more and more attraction in both research and engineering practice. An accurate prediction of the spudcan penetration depth is quite instrumental in deciding on whether a jack-up unit is feasible to operate at the site. The prediction of a too large penetration depth may lead to the hesitation or even rejection of a site due to potential difficulties in the subsequent extraction process; the same is true of a too small depth prediction due to the problem of possible instability during operation. However, a deviation between predictive results and final field data usually exists, especially when a strong-over-soft soil is included in the strata. The ultimate decision sometimes to a great extent depends on the practical experience, not the predictive results given by the guideline. It is somewhat risky, but no choice. Therefore, a feasible predictive method for the spudcan penetration depth, especially in strata with strong-over-soft soil profile, is urgently needed by the jack-up industry. In view of this, a comprehensive investigation on methods of predicting spudcan penetration is executed. For types of different soil profiles, predictive methods for spudcan penetration depth are proposed, and the corresponding experiment is also conducted to validate these methods. In addition, to further verify the feasibility of the proposed methods, a practical engineering case encountered in the South China Sea is also presented, and the corresponding numerical and experimental results are also presented and discussed.
文摘In this paper, the jacket platform is simulated by a non-uniform cantilever beam subjected to axial force. Based on the Hamilton theory, the equation of bending motion is developed and solved by the classical Ritz method combined with the pseudo-excitation method for random responses with non-classical damping. Usually, random responses of this continuous structure are obtained by orthogonality of modes, and some normal modes of the structure are needed, causing inconvenience for the analysis of the non-uniform beam whose normal modes are not easy to be obtained. However, if the pseudo-excitation method is extended to calculate random responses by combining it with the classical Ritz method, the responses of a non-uniform beam, such as auto-PSD function, cross-PSD and higher spectral moments, can be solved directly avoiding the calculation of normal modes. The numerical results show that the present method is effective and useful in aseismic design of platforms.
文摘Condensed and hydrolysable tannins are non-toxic natural polyphenols that are a commercial commodity industrialized for tanning hides to obtain leather and for a growing number of other industrial applications mainly to substitute petroleum-based products.They are a definite class of sustainable materials of the forestry industry.They have been in operation for hundreds of years to manufacture leather and now for a growing number of applications in a variety of other industries,such as wood adhesives,metal coating,pharmaceutical/medical applications and several others.This review presents the main sources,either already or potentially commercial of this forestry by-materials,their industrial and laboratory extraction systems,their systems of analysis with their advantages and drawbacks,be these methods so simple to even appear primitive but nonetheless of proven effectiveness,or very modern and instrumental.It constitutes a basic but essential summary of what is necessary to know of these sustainable materials.In doing so,the review highlights some of the main challenges that remain to be addressed to deliver the quality and economics of tannin supply necessary to fulfill the industrial production requirements for some materials-based uses.
基金The project is supported by the National Natural Science Foundation of China
文摘In this paper a simplified computation method of natural frequency of jacket platforms is given. Shear, bending and rotary inertia effects are considered in the equation, while the jacket shape, rotary inertia and centralized mass of the platform top are all determined by using a coefficient-revising method.
文摘The purpose of this study was to examine the burnout levels of research assistants in Ondokuz Mayis University and to examine the results of multiple linear regression model based on the results obtained from Maslach Burnout Scale with Jackknife Method in terms of validity and generalizability. To do this, a questionnaire was given to 11 research assistants working at Ondokuz Mayis University and the burnout scores of this questionnaire were taken as the dependent variable of the multiple linear regression model. The variable of burnout was explained with the variables of age, weekly hours of classes taught, monthly average credit card debt, numbers of published articles and reports, gender, marital status, number of children and the departments of the research assistants. Dummy variables were assigned to the variables of gender, marital status, number of children and the departments of the research assistants and thus, they were made quantitative. The significance of the model as a result of multiple linear regressions was examined through backward elimination method. After this, for the five explanatory variables which influenced the variable of burnout, standardized model coefficients and coefficients of determination, and 95% confidence intervals of these values were estimated through Jackknife Method and the generalizability of the parameter estimation results of these variables on population was researched.
基金supported by the National Key Research and Development Program of China(No.2023YFC2907600)the National Natural Science Foundation of China(Nos.42077267,42277174 and 52074164)+2 种基金the Natural Science Foundation of Shandong Province,China(No.ZR2020JQ23)the Opening Project of State Key Laboratory of Explosion Science and Technology,Beijing Institute of Technology(No.KFJJ21-02Z)the Fundamental Research Funds for the Central Universities,China(No.2022JCCXSB03).
文摘The technology of drilling tests makes it possible to obtain the strength parameter of rock accurately in situ. In this paper, a new rock cutting analysis model that considers the influence of the rock crushing zone(RCZ) is built. The formula for an ultimate cutting force is established based on the limit equilibrium principle. The relationship between digital drilling parameters(DDP) and the c-φ parameter(DDP-cφ formula, where c refers to the cohesion and φ refers to the internal friction angle) is derived, and the response of drilling parameters and cutting ratio to the strength parameters is analyzed. The drillingbased measuring method for the c-φ parameter of rock is constructed. The laboratory verification test is then completed, and the difference in results between the drilling test and the compression test is less than 6%. On this basis, in-situ rock drilling tests in a traffic tunnel and a coal mine roadway are carried out, and the strength parameters of the surrounding rock are effectively tested. The average difference ratio of the results is less than 11%, which verifies the effectiveness of the proposed method for obtaining the strength parameters based on digital drilling. This study provides methodological support for field testing of rock strength parameters.
基金The Guangdong Basic and Applied Basic Research Foundation(2022A1515010730)National Natural Science Foundation of China(32001647)+2 种基金National Natural Science Foundation of China(31972022)Financial and moral assistance supported by the Guangdong Basic and Applied Basic Research Foundation(2019A1515011996)111 Project(B17018)。
文摘In this study,the structural characters,antioxidant activities and bile acid-binding ability of sea buckthorn polysaccharides(HRPs)obtained by the commonly used hot water(HRP-W),pressurized hot water(HRP-H),ultrasonic(HRP-U),acid(HRP-C)and alkali(HRP-A)assisted extraction methods were investigated.The results demonstrated that extraction methods had significant effects on extraction yield,monosaccharide composition,molecular weight,particle size,triple-helical structure,and surface morphology of HRPs except for the major linkage bands.Thermogravimetric analysis showed that HRP-U with filamentous reticular microstructure exhibited better thermal stability.The HRP-A with the lowest molecular weight and highest arabinose content possessed the best antioxidant activities.Moreover,the rheological analysis indicated that HRPs with higher galacturonic acid content and molecular weight showed higher viscosity and stronger crosslinking network(HRP-C,HRP-W and HRP-U),which exhibited stronger bile acid binding capacity.The present findings provide scientific evidence in the preparation technology of sea buckthorn polysaccharides with good antioxidant and bile acid binding capacity which are related to the structure affected by the extraction methods.
基金financially supported by the Natural Science Foundation of Heilongjiang Province of China (Grant No. LH2020E016)the National Natural Science Foundation of China (Grant No.11472076)。
文摘Offshore platforms are susceptible to structural damage due to prolonged exposure to random loads,such as wind,waves,and currents.This is particularly true for platforms that have been in service for an extended period.Identifying the modal parameters of offshore platforms is crucial for damage diagno sis,as it serves as a prerequisite and foundation for the process.Therefore,it holds great significance to prioritize the identification of these parameters.Aiming at the shortcomings of the traditional Fast Bayesian Fast Fourier Transform(FBFFT) method,this paper proposes a modal parameter identification method based on Automatic Frequency Domain Decomposition(AFDD) and optimized FBFFT.By introducing the AFDD method and Powell optimization algorithm,this method can automatically identify the initial value of natural frequency and solve the objective function efficiently and simply.In order to verify the feasibility and effectiveness of the proposed method,it is used to identify the modal parameters of the IASC-ASCE benchmark model and the j acket platform structure model,and the Most Probable Value(MPV) of the modal parameters and their respective posterior uncertainties are successfully identified.The identification results of the IASC-ASCE benc hmark model are compared with the identification re sults of the MODE-ID method,which verifies the effectivene ss and accuracy of the proposed method for identifying modal parameters.It provides a simple and feasible method for quantifying the influence of uncertain factors such as environmental parameters on the identification results,and also provide s a reference for modal parameter identification of other large structures.
基金The financial supports from National Outstanding Youth Science Fund Project of National Natural Science Foundation of China(Grant No.52022112)the International Postdoctoral Exchange Fellowship Program(Talent-Introduction Program,Grant No.YJ20220219)。
文摘The material point method(MPM)has been gaining increasing popularity as an appropriate approach to the solution of coupled hydro-mechanical problems involving large deformation.In this paper,we survey the current state-of-the-art in the MPM simulation of hydro-mechanical behaviour in two-phase porous geomaterials.The review covers the recent advances and developments in the MPM and their extensions to capture the coupled hydro-mechanical problems involving large deformations.The focus of this review is aiming at providing a clear picture of what has or has not been developed or implemented for simulating two-phase coupled large deformation problems,which will provide some direct reference for both practitioners and researchers.
文摘In this paper a nonlinear response of a fixed offshore platform under the combined forces of waves, wind and sea currents is presented. Wave force acting on the elements is calculated using Morison equation. Hydrodynamic loads on horizontal and vertical tubular members and the dynamic response of offshore fixed platform coupled with distribution of displacement, axial force, and bending moment along the base of the platform for regular and severe cases have been investigated. The structure must be able maintain production in a one-year wave return period condition and also to be able to continue with one hundred-year storm return period. The results of this study show that bending moment values with a one-year wave return period condition for the base platform and junction of platform to deck are 70 percent and 59 percent, respectively more than bending moment with a one-year wave return period. The direction of wave and wind hit has significant effects on the shift platform response, also nonlinear response is important for the safe design and operation of offshore structures.
基金supported by funds from the National Natural Science Foundation of China (Grant No. T2341008)。
文摘Gastric cancer(GC), the fifth most common cancer globally, remains the leading cause of cancer deaths worldwide. Inflammation-induced tumorigenesis is the predominant process in GC development;therefore, systematic research in this area should improve understanding of the biological mechanisms that initiate GC development and promote cancer hallmarks. Here, we summarize biological knowledge regarding gastric inflammation-induced tumorigenesis, and characterize the multi-omics data and systems biology methods for investigating GC development. Of note, we highlight pioneering studies in multi-omics data and state-of-the-art network-based algorithms used for dissecting the features of gastric inflammation-induced tumorigenesis, and we propose translational applications in early GC warning biomarkers and precise treatment strategies. This review offers integrative insights for GC research, with the goal of paving the way to novel paradigms for GC precision oncology and prevention.
基金supported as part of the Center for Hierarchical Waste Form Materials,an Energy Frontier Research Center funded by the U.S.Department of Energy,Office of Science,Basic Energy Sciences under Award No.DE-SC0016574.
文摘Porous materials present significant advantages for absorbing radioactive isotopes in nuclear waste streams.To improve absorption efficiency in nuclear waste treatment,a thorough understanding of the diffusion-advection process within porous structures is essential for material design.In this study,we present advancements in the volumetric lattice Boltzmann method(VLBM)for modeling and simulating pore-scale diffusion-advection of radioactive isotopes within geopolymer porous structures.These structures are created using the phase field method(PFM)to precisely control pore architectures.In our VLBM approach,we introduce a concentration field of an isotope seamlessly coupled with the velocity field and solve it by the time evolution of its particle population function.To address the computational intensity inherent in the coupled lattice Boltzmann equations for velocity and concentration fields,we implement graphics processing unit(GPU)parallelization.Validation of the developed model involves examining the flow and diffusion fields in porous structures.Remarkably,good agreement is observed for both the velocity field from VLBM and multiphysics object-oriented simulation environment(MOOSE),and the concentration field from VLBM and the finite difference method(FDM).Furthermore,we investigate the effects of background flow,species diffusivity,and porosity on the diffusion-advection behavior by varying the background flow velocity,diffusion coefficient,and pore volume fraction,respectively.Notably,all three parameters exert an influence on the diffusion-advection process.Increased background flow and diffusivity markedly accelerate the process due to increased advection intensity and enhanced diffusion capability,respectively.Conversely,increasing the porosity has a less significant effect,causing a slight slowdown of the diffusion-advection process due to the expanded pore volume.This comprehensive parametric study provides valuable insights into the kinetics of isotope uptake in porous structures,facilitating the development of porous materials for nuclear waste treatment applications.
基金This work is funded by the National Natural Science Foundation of China(Grant Nos.42377164 and 52079062)the National Science Fund for Distinguished Young Scholars of China(Grant No.52222905).
文摘In the existing landslide susceptibility prediction(LSP)models,the influences of random errors in landslide conditioning factors on LSP are not considered,instead the original conditioning factors are directly taken as the model inputs,which brings uncertainties to LSP results.This study aims to reveal the influence rules of the different proportional random errors in conditioning factors on the LSP un-certainties,and further explore a method which can effectively reduce the random errors in conditioning factors.The original conditioning factors are firstly used to construct original factors-based LSP models,and then different random errors of 5%,10%,15% and 20%are added to these original factors for con-structing relevant errors-based LSP models.Secondly,low-pass filter-based LSP models are constructed by eliminating the random errors using low-pass filter method.Thirdly,the Ruijin County of China with 370 landslides and 16 conditioning factors are used as study case.Three typical machine learning models,i.e.multilayer perceptron(MLP),support vector machine(SVM)and random forest(RF),are selected as LSP models.Finally,the LSP uncertainties are discussed and results show that:(1)The low-pass filter can effectively reduce the random errors in conditioning factors to decrease the LSP uncertainties.(2)With the proportions of random errors increasing from 5%to 20%,the LSP uncertainty increases continuously.(3)The original factors-based models are feasible for LSP in the absence of more accurate conditioning factors.(4)The influence degrees of two uncertainty issues,machine learning models and different proportions of random errors,on the LSP modeling are large and basically the same.(5)The Shapley values effectively explain the internal mechanism of machine learning model predicting landslide sus-ceptibility.In conclusion,greater proportion of random errors in conditioning factors results in higher LSP uncertainty,and low-pass filter can effectively reduce these random errors.