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An Ultrastructural Study of Phagocytosis and Transport of Formalized Campylobacter jejuni By M Cells into Mouse Peyer's Patches
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作者 王维亚 郭仁强 《The Journal of Biomedical Research》 CAS 1994年第1期41-44,共4页
Suspension of formalized Campylobacter jejunt (2×10 CFU/ml)was injected into a bothend-ligated intestinal loop of ileum which contained some Peyer's patches from non-immunized adult mice after laparotomy unde... Suspension of formalized Campylobacter jejunt (2×10 CFU/ml)was injected into a bothend-ligated intestinal loop of ileum which contained some Peyer's patches from non-immunized adult mice after laparotomy under anesthesia.After 1-hour post inoculation, the specimen was taken out and prepared for TEM and SEM observation.The results showed that bacteria adhered specifically on the surface of M cells of Peyer's patches.The microvilli and microfolds of the M cells fused to capture the bacteria and to form a large endocytotic vesicle in the cytoplasm of the M cell,then transported inward,and, at last.released into the central cavity between lymphocytes.Occasionally, we found some of them were phagocytosed by lymphocytes. 展开更多
关键词 M cell Campylobacter jejunt transepithelial transport Peyer's patch
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运动轴索型格林-巴利综合征患者血清对神经轴索损害作用的研究 被引量:2
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作者 赵晓燕 薛平 +5 位作者 刘瑞春 李春岩 王桂荣 杨程 王红杰 易建平 《脑与神经疾病杂志》 1998年第4期200-203,共4页
应用含有高效价空肠弯曲菌抗体的急性运动性轴索型格林-巴利综合征病人的血清浸泡8只在体新西兰兔坐骨神经。14天后病理检查显示4只兔的坐骨神经均有20%~30%的纤维发生轴索变性,而髓鞘相对正常。而其他神经疾病组血清、健康成人组血清... 应用含有高效价空肠弯曲菌抗体的急性运动性轴索型格林-巴利综合征病人的血清浸泡8只在体新西兰兔坐骨神经。14天后病理检查显示4只兔的坐骨神经均有20%~30%的纤维发生轴索变性,而髓鞘相对正常。而其他神经疾病组血清、健康成人组血清做同样实验获阴性病理结果。本实验表明:AMAN 患者血清中含有致病因子,此致病因子可能是抗空肠弯曲菌抗体并介导了神经轴索的损害。 展开更多
关键词 格林巴利综合征 抗体 空肠弯曲菌 AMAN
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