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Superconducting joints using reacted multifilament MgB_(2)wires:A technology toward cryogen-free MRI magnets
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作者 Dipak Patel Akiyoshi Matsumoto +8 位作者 Hiroaki Kumakura Yuka Hara Toru Hara Minoru Maeda Hao Liang Yusuke Yamauchi Seyong Choi Jung Ho Kim Md Shahriar A.Hossain 《Journal of Magnesium and Alloys》 SCIE EI CAS CSCD 2024年第1期159-170,共12页
The development of superconducting joining technology for reacted magnesium diboride(MgB_(2))conductors remains a critical challenge for the advancement of cryogen-free MgB_(2)-based magnets for magnetic resonance ima... The development of superconducting joining technology for reacted magnesium diboride(MgB_(2))conductors remains a critical challenge for the advancement of cryogen-free MgB_(2)-based magnets for magnetic resonance imaging(MRI).Herein,the fabrication of superconducting joints using reacted carbon-doped multifilament MgB_(2)wires for MRI magnets is reported.To achieve successful superconducting joints,the powder-in-mold method was employed,which involved tuning the filament protection mechanism,the powder compaction pressure,and the heat treatment condition.The fabricated joints demonstrated clear superconducting-to-normal transitions in self-field,with effective magnetic field screening up to 0.5 T at 20 K.To evaluate the interface between one of the MgB_(2)filaments and the MgB_(2)bulk within the joint,serial sectioning was conducted for the first time in this type of superconducting joint.The serial sectioning revealed space formation at the interface,potentially caused by the volume shrinkage associated with the MgB_(2)formation or the combined effect of the volume shrinkage and the different thermal expansion coefficients of the MgB_(2)bulk,the filament,the mold,and the sealing material.These findings are expected to be pivotal in developing MgB_(2)superconducting joining technology for MRI magnet applications through interface engineering. 展开更多
关键词 Mg B2 superconducting joint MgB_(2)conductor MRI applications Cryogen-free magnet Persistent-mode operation
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关刺法不同针刺频率及留针时效对膝骨性关节炎患者疼痛、最大主动关节活动度及血清FGF-2水平的影响
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作者 刘欣 赵莹 +3 位作者 王冠军 张月亮 王娜 吕笑星 《针灸临床杂志》 2024年第5期41-45,共5页
目的:探究关刺法不同针刺频率及留针时效对膝骨性关节炎(KOA)患者疼痛、最大主动关节活动度及血清成纤维细胞生长因子-2(FGF-2)水平的影响。方法:将100例KOA患者随机分为关刺1组(50例,治疗时需留针40 min, 3 d/次)与关刺2组(50例,治疗... 目的:探究关刺法不同针刺频率及留针时效对膝骨性关节炎(KOA)患者疼痛、最大主动关节活动度及血清成纤维细胞生长因子-2(FGF-2)水平的影响。方法:将100例KOA患者随机分为关刺1组(50例,治疗时需留针40 min, 3 d/次)与关刺2组(50例,治疗时需留针30 min, 2 d/次),治疗3周后,观察比较两组患者治疗前后的疼痛评分、骨关节炎指数(WOMAC)评分、最大主动关节活动度及血清FGF-2水平的变化情况。结果:关刺1组总有效率(45/50,90.00%),关刺2组总有效率(48/50,96.00%),两组比较差异无统计学意义(P>0.05)。治疗后,关刺1组、关刺2组KOA患者的疼痛评分和WOMAC评分(关节功能评分、僵硬评分、疼痛评分与总分)均低于治疗前,差异具有统计学意义(P<0.05),关刺2组KOA患者的疼痛评分、WOMAC评分(关节功能评分、僵硬评分、疼痛评分与总分)均低于关刺1组,差异具有统计学意义(P<0.05);关刺1组、关刺2组KOA患者的最大主动关节活动度和血清FGF-2表达水平均高于治疗前,差异具有统计学意义(P<0.05),关刺2组KOA患者的最大主动关节活动度、血清FGF-2表达水平均高于关刺1组,差异具有统计学意义(P<0.05);两组治疗期间均未出现明显的不良反应。结论:采用关刺法留针30 min, 2 d 1次的方法治疗KOA效果确切,可降低患者疼痛程度,提高血清FGF-2水平,并能改善患者最大主动关节活动度。 展开更多
关键词 膝骨性关节炎 关刺法 针刺 频率 关节活动度 成纤维细胞生长因子-2
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“3+2”联合培养模式下本科层次职业教育数学课程衔接发展研究——以安徽机电职业技术学院为例
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作者 刘苏兵 尤游 +1 位作者 吕会影 周长远 《安徽警官职业学院学报》 2024年第1期115-119,共5页
“3+2”联合培养模式是本科层次职业教育的主要模式之一,有利于提升本科教育与职业教育的课程衔接效果。以安徽机电职业技术学院为例,剖析本科层次职业教育数学课程衔接背景与课程开展现状,从目标衔接、内容衔接、教法衔接、考核评价衔... “3+2”联合培养模式是本科层次职业教育的主要模式之一,有利于提升本科教育与职业教育的课程衔接效果。以安徽机电职业技术学院为例,剖析本科层次职业教育数学课程衔接背景与课程开展现状,从目标衔接、内容衔接、教法衔接、考核评价衔接等方面,深入分析本科层次职业教育数学课程衔接发展的措施,有助于为“3+2”联合培养模式下本科与职业教育数学课程的顺利衔接提供参考。 展开更多
关键词 3+2联合培养模式 本科层次职业教育 数学课程 安徽机电职业技术学院
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Vertex centrality of complex networks based on joint nonnegative matrix factorization and graph embedding
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作者 卢鹏丽 陈玮 《Chinese Physics B》 SCIE EI CAS CSCD 2023年第1期634-645,共12页
Finding crucial vertices is a key problem for improving the reliability and ensuring the effective operation of networks,solved by approaches based on multiple attribute decision that suffer from ignoring the correlat... Finding crucial vertices is a key problem for improving the reliability and ensuring the effective operation of networks,solved by approaches based on multiple attribute decision that suffer from ignoring the correlation among each attribute or the heterogeneity between attribute and structure. To overcome these problems, a novel vertex centrality approach, called VCJG, is proposed based on joint nonnegative matrix factorization and graph embedding. The potential attributes with linearly independent and the structure information are captured automatically in light of nonnegative matrix factorization for factorizing the weighted adjacent matrix and the structure matrix, which is generated by graph embedding. And the smoothness strategy is applied to eliminate the heterogeneity between attributes and structure by joint nonnegative matrix factorization. Then VCJG integrates the above steps to formulate an overall objective function, and obtain the ultimately potential attributes fused the structure information of network through optimizing the objective function. Finally, the attributes are combined with neighborhood rules to evaluate vertex's importance. Through comparative analyses with experiments on nine real-world networks, we demonstrate that the proposed approach outperforms nine state-of-the-art algorithms for identification of vital vertices with respect to correlation, monotonicity and accuracy of top-10 vertices ranking. 展开更多
关键词 complex networks CENTRALITY joint nonnegative matrix factorization graph embedding smoothness strategy
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Recent progress in MgB_(2)superconducting joint technology
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作者 Hao Liang Dipak Patel +6 位作者 Mahboobeh Shahbazi Andrzej Morawski Daniel Gajda Matt Rindfleisch Richard Taylor Yusuke Yamauchi Md Shahriar A.Hossain 《Journal of Magnesium and Alloys》 SCIE EI CAS CSCD 2023年第7期2217-2229,共13页
Magnesium diboride(MgB_(2))magnets have the potential to be the next-generation liquid-helium-free magnet for magnetic resonance imaging(MRI)application due to their relatively high superconducting transition temperat... Magnesium diboride(MgB_(2))magnets have the potential to be the next-generation liquid-helium-free magnet for magnetic resonance imaging(MRI)application due to their relatively high superconducting transition temperature,high current density and low raw material cost compared with current commercial niobium-titanium(Nb-Ti)magnets.A typical superconducting magnet includes several coils.To produce an ultra-stable magnetic field for imaging in MRI,a superconducting electromagnet operating in a persistent mode is crucial.Superconducting coils of the electromagnet in MRI are short-circuited to operate in the persistent mode by connecting coils with superconducting joints.Per-sistent joints have been demonstrated for in-situ and ex-situ wires of both mono-and multi-filamentary structures,made predominantly by PIT techniques similar to those used in wire production.To realise further engagement of MgB_(2)in MRI applications,enhancing the performance of MgB_(2)superconducting joints is essential.This literature review summarises research and development on MgB_(2)superconducting joining technology. 展开更多
关键词 MgB_(2) Superconducting joints Persistent-mode magnets MRI application Field-decay measurement
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Numerical simulation study on shear resistance of anchorage joints considering tensile-shear fracture criterion of 2G-NPR bolt
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作者 Shulin Ren Zhigang Tao +2 位作者 Manchao He Mengnan Li Qiru Sui 《International Journal of Coal Science & Technology》 EI CAS CSCD 2023年第4期186-202,共17页
2G-NPR bolt (the 2nd generation Negative Poisson’s Ratio bolt) is a new type of bolt with high strength, high toughness and no yield platform. It has signifcant efects on improving the shear strength of jointed rock ... 2G-NPR bolt (the 2nd generation Negative Poisson’s Ratio bolt) is a new type of bolt with high strength, high toughness and no yield platform. It has signifcant efects on improving the shear strength of jointed rock mass and controlling the stability of surrounding rock. To achieve an accurate simulation of bolted joint shear tests, we have studied a numerical simulation method that takes into account the 2G-NPR bolt's tensile–shear fracture criterion. Firstly, the indoor experimental study on the tensile–shear mechanical properties of 2G-NPR bolt is carried out to explore its mechanical properties under diferent tensile–shear angles, and the fracture criterion of 2G-NPR bolt considering the tensile–shear angle is established. Then, a three-dimensional numerical simulation method considering the tensile–shear mechanical constitutive and fracture criterion of 2G-NPR bolt, the elastoplastic mechanical behavior of surrounding rock and the damage and deterioration of grouting body is proposed. The feasibility and accuracy of the method are verifed by comparing with the indoor shear test results of 2G-NPR bolt anchorage joints. Finally, based on the numerical simulation results, the deformation and stress of the bolt, the distribution of the plastic zone of the rock mass, the stress distribution and the damage of the grouting body are analyzed in detail. The research results can provide a good reference value for the practical engineering application and shear mechanical performance analysis of 2G-NPR bolt. 展开更多
关键词 Anchorage joints 2G-NPR bolt Tensile-shear fracture criterion Shear behavior Numerical simulation
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Cognitive J^(2)SAC:Joint Jamming,Sensing,and Communication Under Antagonistic Environment
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作者 Jiangchun Gu Guoru Ding +3 位作者 Yizhen Yin Haichao Wang Yitao Xu Yehui Song 《China Communications》 SCIE CSCD 2023年第9期78-95,共18页
Integrated sensing and communication(ISAC)is regarded as a recent advanced technology,which is expected to realize the dual functions of sensing and communication simultaneously in one system.Nevertheless,it still fac... Integrated sensing and communication(ISAC)is regarded as a recent advanced technology,which is expected to realize the dual functions of sensing and communication simultaneously in one system.Nevertheless,it still faces the challenges of the information security and transmission robustness caused by the openness of wireless channel,especially under antagonistic environment.Hence,this article develops a generalized framework,named cognitive joint jamming,sensing and communication(cognitive J2SAC),to empower the current sensing/communication/jamming system with a“brain”for realizing precise sensing,reliable communication and effective jamming under antagonistic environment.Three kinds of gains can be captured by cognitive J2SAC,including integrated gain,cooperative gain and cognitive gain.Moreover,we highlight the enabling mechanism among jamming,sensing,and communication,as well as illustrating several typical use cases of cognitive J2SAC.Furthermore,several key enabled technologies are analyzed and a typical sensing enhance integrated communication and jamming case study is discussed to verify the effectiveness of the proposed method.Last but not the least,the future directions are listed before concluding this article.Integrated sensing and communication(ISAC)is regarded as a recent advanced technology,which is expected to realize the dual functions of sensing and communication simultaneously in one system.Nevertheless,it still faces the challenges of the information security and transmission robustness caused by the openness of wireless channel,especially under antagonistic environment.Hence,this article develops a generalized framework,named cognitive joint jamming,sensing and communication(cognitive J2SAC),to empower the current sensing/communication/jamming system with a“brain”for realizing precise sensing,reliable communication and effective jamming under antagonistic environment.Three kinds of gains can be captured by cognitive J2SAC,including integrated gain,cooperative gain and cognitive gain.Moreover,we highlight the enabling mechanism among jamming,sensing,and communication,as well as illustrating several typical use cases of cognitive J2SAC.Furthermore,several key enabled technologies are analyzed and a typical sensing enhance integrated communication and jamming case study is discussed to verify the effectiveness of the proposed method.Last but not the least,the future directions are listed before concluding this article. 展开更多
关键词 integrated sensing and communication(ISAC) information security joint jamming sensing and communication(J2SAC) cognition theory
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一类仙人掌图的D(2)-点可区别全染色
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作者 汪银芳 李沐春 王国兴 《吉林大学学报(理学版)》 CAS 北大核心 2024年第1期1-6,共6页
用数学归纳法和组合分析法给出最大度为3的仙人掌图G T的D(2)-点可区别全染色,进而得到χ_(2vt)(G T)≤6.结果表明,D(β)-VDTC猜想对最大度为3的仙人掌图成立.
关键词 仙人掌图 D(2)-点可区别全染色 D(2)-点可区别全色数
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新型电极Mg_(2)SiNi_(3)与Mg_(2)Si的连接和界面行为研究
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作者 陈彦佐 陈少平 +1 位作者 樊文浩 徐礼彬 《热加工工艺》 北大核心 2024年第8期93-97,103,共6页
Mg_(2)Si基热电材料是中温区间最有前途的热电材料之一。为了提高Mg_(2)Si基热电接头的界面性能,提出了一种新型电极材料Mg_(2)SiNi_(3)作为Mg_(2)Si的电极材料,并采用放电等离子烧结技术(SPS)实现了Mg_(2)SiNi_(3)和Mg_(2)Si的连接。同... Mg_(2)Si基热电材料是中温区间最有前途的热电材料之一。为了提高Mg_(2)Si基热电接头的界面性能,提出了一种新型电极材料Mg_(2)SiNi_(3)作为Mg_(2)Si的电极材料,并采用放电等离子烧结技术(SPS)实现了Mg_(2)SiNi_(3)和Mg_(2)Si的连接。同时,测试分析了所得接头的界面微观形貌、界面电性能、力学性能以及稳定性。结果表明,Mg_(2)SiNi_(3)与Mg_(2)Si烧结后形成了完整的冶金结合,界面处各组成元素均实现了均匀过渡;界面接触电阻得到了有效地优化,而且接头以及界面稳定性良好;时效前后,界面性能均未出现大幅的退化。Mg_(2)SiNi_(3)的提出为Mg_(2)Si基热电器件设计和集成提供了一种新的思路。 展开更多
关键词 扩散连接 Mg_(2)Si Mg_(2)SiNi_(3) 热电接头 界面性能
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On the 2-Domination Number of Complete Grid Graphs
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作者 Ramy Shaheen Suhail Mahfud Khames Almanea 《Open Journal of Discrete Mathematics》 2017年第1期32-50,共19页
A set D of vertices of a graph G = (V, E) is called k-dominating if every vertex v ∈V-D is adjacent to some k vertices of D. The k-domination number of a graph G, γk (G), is the order of a smallest k-dominating set ... A set D of vertices of a graph G = (V, E) is called k-dominating if every vertex v ∈V-D is adjacent to some k vertices of D. The k-domination number of a graph G, γk (G), is the order of a smallest k-dominating set of G. In this paper we calculate the k-domination number (for k = 2) of the product of two paths Pm × Pn for m = 1, 2, 3, 4, 5 and arbitrary n. These results were shown an error in the paper [1]. 展开更多
关键词 k-Dominating SET K-DOMINATION NUMBER 2-Dominating SET 2-Domination NUMBER CARTESIAN Product graphs PATHS
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Nomogram model including LATS2 expression was constructed to predict the prognosis of advanced gastric cancer after surgery
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作者 Nan Sun Bi-Bo Tan Yong Li 《World Journal of Gastrointestinal Surgery》 SCIE 2024年第2期518-528,共11页
BACKGROUND Gastric cancer is a leading cause of cancer-related deaths worldwide.Prognostic assessments are typically based on the tumor-node-metastasis(TNM)staging system,which does not account for the molecular heter... BACKGROUND Gastric cancer is a leading cause of cancer-related deaths worldwide.Prognostic assessments are typically based on the tumor-node-metastasis(TNM)staging system,which does not account for the molecular heterogeneity of this disease.LATS2,a tumor suppressor gene involved in the Hippo signaling pathway,has been identified as a potential prognostic biomarker in gastric cancer.AIM To construct and validate a nomogram model that includes LATS2 expression to predict the survival prognosis of advanced gastric cancer patients following ra-dical surgery,and compare its predictive performance with traditional TNM staging.METHODS A retrospective analysis of 245 advanced gastric cancer patients from the Fourth Hospital of Hebei Medical University was conducted.The patients were divided into a training group(171 patients)and a validation group(74 patients)to deve-lop and test our prognostic model.The performance of the model was determined using C-indices,receiver operating characteristic curves,calibration plots,and decision curves.RESULTS The model demonstrated a high predictive accuracy with C-indices of 0.829 in the training set and 0.862 in the validation set.Area under the curve values for three-year and five-year survival prediction were significantly robust,suggesting an excellent discrimination ability.Calibration plots confirmed the high concordance between the predictions and actual survival outcomes.CONCLUSION We developed a nomogram model incorporating LATS2 expression,which significantly outperformed conven-tional TNM staging in predicting the prognosis of advanced gastric cancer patients postsurgery.This model may serve as a valuable tool for individualized patient management,allowing for more accurate stratification and im-proved clinical outcomes.Further validation in larger patient cohorts will be necessary to establish its generaliza-bility and clinical utility. 展开更多
关键词 Gastric cancer LATS2 Column line graph PROGNOSIS Advanced gastric cancer survival Molecular biomarkers Predictive analytics in oncology Survival analysis
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Schultz Polynomials and Their Topological Indices of Jahangir Graphs J2,m
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作者 Shaohui Wang Mohammad Reza Farahani +1 位作者 M. R. Rajesh Kanna R. Pradeep Kumar 《Applied Mathematics》 2016年第14期1632-1637,共6页
Let G = (V;E) be a simple connected graph. The Wiener index is the sum of distances between all pairs of vertices of a connected graph. The Schultz topological index is equal to and the Modified Schultz topological in... Let G = (V;E) be a simple connected graph. The Wiener index is the sum of distances between all pairs of vertices of a connected graph. The Schultz topological index is equal to and the Modified Schultz topological index is . In this paper, the Schultz, Modified Schultz polynomials and their topological indices of Jahangir graphs J<sub>2,m</sub> for all integer number m ≥ 3 are calculated. 展开更多
关键词 Molecular Topological Index Schultz Index Schultz Polynomials Jahangir graphs J2 m
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H- and H<sub>2</sub>-Cordial Labeling of Some Graphs
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作者 Freeda Selvanayagom Robinson S. Chellathurai 《Open Journal of Discrete Mathematics》 2012年第4期149-155,共7页
In this paper we prove that the join of two path graphs, two cycle graphs, Ladder graph and the tensor product are H2-cordial labeling. Further we prove that the join of two wheel graphs Wn and Wm, (mod 4) admits a H-... In this paper we prove that the join of two path graphs, two cycle graphs, Ladder graph and the tensor product are H2-cordial labeling. Further we prove that the join of two wheel graphs Wn and Wm, (mod 4) admits a H-cordial labeling. 展开更多
关键词 H-Cordial H2-Cordial JOIN of Two graphs Split graphs
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<i>L</i>(2,1)-Labeling of the Brick Product Graphs
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作者 Xiujun Zhang Hong Yang Hong Li 《Journal of Applied Mathematics and Physics》 2017年第8期1529-1536,共8页
A k-L(2,1)-labeling for a graph G is a function such that whenever and whenever u and v are at distance two apart. The λ-number for G, denoted by λ(G), is the minimum k over all k-L(2,1)-labelings of G. In this pape... A k-L(2,1)-labeling for a graph G is a function such that whenever and whenever u and v are at distance two apart. The λ-number for G, denoted by λ(G), is the minimum k over all k-L(2,1)-labelings of G. In this paper, we show that for or 11, which confirms Conjecture 6.1 stated in [X. Li, V. Mak-Hau, S. Zhou, The L(2,1)-labelling problem for cubic Cayley graphs on dihedral groups, J. Comb. Optim. (2013) 25: 716-736] in the case when or 11. Moreover, we show that? if 1) either (mod 6), m is odd, r = 3, or 2) (mod 3), m is even (mod 2), r = 0. 展开更多
关键词 graph LABELING BRICK Product graph L((2 1)-Labeling Frequency ASSIGNMENT Problem
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A Note on SK, SK<sub>1</sub>, SK<sub>2</sub>Indices of Interval Weighted Graphs
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作者 Semiha Başdaş Nurkahlı Şerife Büyükköse 《Advances in Linear Algebra & Matrix Theory》 2021年第1期14-20,共7页
In this study, the SK, SK<sub>1</sub> and SK<sub>2</sub> indices are defined on weighted graphs. Then, the SK, SK<sub>1</sub> and SK<sub>2</sub> indices are defined on i... In this study, the SK, SK<sub>1</sub> and SK<sub>2</sub> indices are defined on weighted graphs. Then, the SK, SK<sub>1</sub> and SK<sub>2</sub> indices are defined on interval weighted graphs. Their behaviors are investigated under some graph operations by using these definitions. 展开更多
关键词 SK Index SK1 Index SK2 Index Weighted graph Interval Weighted graph
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三类联图的2-距离和可区别边染色
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作者 王芹 杨超 +1 位作者 殷志祥 姚兵 《华中师范大学学报(自然科学版)》 CAS CSCD 北大核心 2024年第2期178-183,共6页
该文探讨了C_(m)·P_(n)、C_(m)·S_(n)和C_(m)·K_(n)三类联图的2-距离和可区别边染色问题.根据联图的结构特点,利用组合分析法、反证法以及分类讨论思想,得到了这三类联图的2-距离和可区别边色数.结论表明三类联图的2-距... 该文探讨了C_(m)·P_(n)、C_(m)·S_(n)和C_(m)·K_(n)三类联图的2-距离和可区别边染色问题.根据联图的结构特点,利用组合分析法、反证法以及分类讨论思想,得到了这三类联图的2-距离和可区别边色数.结论表明三类联图的2-距离和可区别边色数均不超过Δ+2. 展开更多
关键词 边染色 2-距离和可区别边染色 联图
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一些特殊图的中间图的2-距离和可区别全染色
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作者 王同昕 杨超 姚兵 《兰州理工大学学报》 CAS 北大核心 2024年第3期156-161,共6页
为了进一步研究图的2-距离和可区别全染色问题,根据中间图的构造特点,通过构造染色函数,利用组合分析法得到了路,圈,星,扇,轮,双星以及轮环图的中间图的2-距离和可区别全色数.
关键词 全染色 2-距离和可区别全染色 中间图
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毛兰素调节CCL2⁃CCR2轴对关节软骨细胞炎性损伤的影响
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作者 樊增荣 蒋勇 刘德洪 《中国骨质疏松杂志》 CAS CSCD 北大核心 2024年第3期335-340,354,共7页
目的探讨毛兰素调节CC趋化因子配体2(CCL2)/CC趋化因子受体2(CCR2)轴对关节软骨细胞炎性损伤的影响。方法将人关节软骨细胞分为control组(正常培养)、LPS组、毛兰素低(10 nmol/L)、中(25 nmol/L)、高(50 nmol/L)剂量组、pcDNA组(转染pcD... 目的探讨毛兰素调节CC趋化因子配体2(CCL2)/CC趋化因子受体2(CCR2)轴对关节软骨细胞炎性损伤的影响。方法将人关节软骨细胞分为control组(正常培养)、LPS组、毛兰素低(10 nmol/L)、中(25 nmol/L)、高(50 nmol/L)剂量组、pcDNA组(转染pcDNA3.1)、pcDNA⁃CCL2组(转染pcDNA3.1⁃CCL2),实时荧光定量PCR(qRT⁃PCR)检测细胞中CCL2、CCR2 mRNA表达水平;MTT法、平板克隆实验与流式细胞仪分别检测细胞增殖和凋亡情况;qRT⁃PCR和ELISA检测IL⁃6、IL⁃1β、TNF⁃α水平;Western blot法检测细胞中增殖细胞核抗原(PCNA)、细胞抗凋亡因子B细胞淋巴瘤蛋白2(Bcl⁃2)、Bcl⁃2相关X蛋白(Bax)及CCL2/CCR2通路蛋白表达。结果与control组比较,LPS组细胞凋亡率、IL⁃6、IL⁃1β、TNF⁃αmRNA表达水平、CCL2、CCR2 mRNA及Bax、CCL2、CCR2蛋白表达水平显著升高,OD490值、集落形成数、PCNA、Bcl⁃2蛋白表达水平降低(P<0.05);与LPS组比较,毛兰素低、中、高剂量组细胞凋亡率、IL⁃6、IL⁃1β、TNF⁃αmRNA表达水平、CCL2、CCR2 mRNA及Bax、CCL2、CCR2蛋白表达水平逐渐降低,OD490值、集落形成数、PCNA、Bcl⁃2蛋白表达水平逐渐升高(P<0.05);过表达CCL2减弱了毛兰素对LPS诱导的关节软骨细胞的影响(P<0.05)。结论毛兰素可抑制LPS诱导的关节软骨细胞凋亡和炎症反应,其机制可能与抑制CCL2/CCR2通路有关。 展开更多
关键词 毛兰素 CC趋化因子配体2 CC趋化因子受体2 关节软骨细胞 炎性损伤
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On Graphs with Equal Connected Domination and 2-connected Domination Numbers
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作者 CHEN Hong-yu ZHU Zhe-li 《Chinese Quarterly Journal of Mathematics》 CSCD 2010年第1期98-103,共6页
如果 S 是一个统治集合,导致的 subgraph 至多有 k 部件, V 的子集 S 被称为一个连接 k 的统治集合。G 的连接 k 的支配数字 kc (G) 是在 G 的所有最小的连接 k 的统治集合上拿的最小的集的势。在这份报纸,我们与相等的连接支配和 2-... 如果 S 是一个统治集合,导致的 subgraph 至多有 k 部件, V 的子集 S 被称为一个连接 k 的统治集合。G 的连接 k 的支配数字 kc (G) 是在 G 的所有最小的连接 k 的统治集合上拿的最小的集的势。在这份报纸,我们与相等的连接支配和 2-connected 支配数字描绘树和 unicyclic 图。 展开更多
关键词 连接支配数字 2-connected 支配数字 uni 周期的图
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液压马达球铰副表面ZrO_(2)涂层的摩擦学性能
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作者 寇保福 张登科 +3 位作者 李振顺 张涨 李瑞清 刘冠臣 《机床与液压》 北大核心 2023年第1期1-6,共6页
为探索表面ZrO_(2)涂层的球铰副在液压马达中的摩擦学规律,采用摩擦磨损试验机和白光干涉仪模拟ZrO_(2)涂层的球铰副在不同载荷和转速的工况下,球铰副在液压马达中的摩擦磨损变化情况。分别从摩擦因数、磨损体积和磨痕形貌分析其摩擦磨... 为探索表面ZrO_(2)涂层的球铰副在液压马达中的摩擦学规律,采用摩擦磨损试验机和白光干涉仪模拟ZrO_(2)涂层的球铰副在不同载荷和转速的工况下,球铰副在液压马达中的摩擦磨损变化情况。分别从摩擦因数、磨损体积和磨痕形貌分析其摩擦磨损规律,从中找到最优的工况去提高ZrO_(2)涂层的球铰副寿命和工作效率。通过开展控制变量试验发现:转速对ZrO_(2)涂层的球铰副摩擦学性能的影响远大于载荷,在100 N-100 r/min时摩擦因数最小为0.0596;磨损体积随载荷和转速的增大而逐渐增大,且在50 N-50 r/min时磨损体积最小为0.184 mm3。综合以上规律发现,载荷100 N和转速50 r/min工况下ZrO_(2)涂层的球铰副减摩抗磨效果最好,低转速能够有效延长液压马达的使用寿命和提高机械效率。 展开更多
关键词 ZrO_(2)涂层球铰副 摩擦磨损 摩擦因数 磨损体积
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