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Maternal-Fetal Pregnancy Complications of in Minors Raped with or without Physical Restraint in Eastern Democratic Republic of Congo
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作者 Kiminyi Kalunga Eloge Ilunga-Mbaya +2 位作者 Raha Maroy Yoyu Tunangoya Jonathan Nyakio Ngeleza Olivier 《Open Journal of Obstetrics and Gynecology》 CAS 2023年第1期1-12,共12页
Introduction: Pregnancy resulting from rape is a public health and sexual and reproductive health issue, especially among minors. Rape can be perpetrated with or without physical restraint. The objective of the presen... Introduction: Pregnancy resulting from rape is a public health and sexual and reproductive health issue, especially among minors. Rape can be perpetrated with or without physical restraint. The objective of the present study is to highlight the prevalence of physical coercion leading to pregnancy and the associated maternal-fetal complications. Methodology: This was a comparative descriptive and analytical cross-sectional study of complications associated with post-rape pregnancy by physical restraint among minors who were treated at the General Reference Hospital of Panzi over a two-year period from June 2020 to June 2022. A total of 140 minor survivors of violence with pregnancy were included in the study. Data were collected using a questionnaire, coded and analyzed in Excel and XLSTAT version 2014. Results: The prevalence of physical constraints was 65%. After mulltivariate analyses, denial of pregnancy (ORa: 9.64 95% CI: 1.1 - 81.2;p-value: 0.0370), attempted abortion (ORa: 56.1 95% CI: 1.5 - 2027.6;p-value: 0.0278) and agitation during delivery (ORa: 88.7 95% CI: 4.5 - 1715;p-value: 0.0030) were the complications associated with pregnancy in minors who experienced physical restraint rape. In addition, BMI was a factor in reducing the risk of physical restraint rape at the ORa of 0.5054 [0.3;0.8];p 0.006). Conclusion: Pregnancy among minors is a reality and occurs in a situation of physical coercion in the eastern Democratic Republic of Congo. These pregnancies are often associated with complications that require an intensive management system since they can jeopardize the maternal-fetal prognosis of minors. 展开更多
关键词 Post-Rape Pregnancy minor Associated Complications Eastern DRC
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Perpetrators of Sexual Violence against Minors in Casamance (Senegal)
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作者 Adama Koundoul Ibra Diagne +4 位作者 Bernadette F. Sambou Issa Wone El Hadji Makhtar Ba Sokhna Seck Papa Lamine Faye 《Open Journal of Psychiatry》 2023年第1期33-44,共12页
Introduction: The causes of sexual delinquency against children are multifactorial and the motivations that drive the perpetrators of sexual assault are diverse. Nowadays, there is still no consensus on a single portr... Introduction: The causes of sexual delinquency against children are multifactorial and the motivations that drive the perpetrators of sexual assault are diverse. Nowadays, there is still no consensus on a single portrait of child sex offenders and studies that focus on sex offenders are still rare in Senegal and Africa. Objectives: To determine the profile of the perpetrators and to identify the circumstances of sexual violence against minors in Casamance. Materials and Methods: A retrospective descriptive and analytical study from April 1, 2014 to October 31, 2019 was conducted. The study population was made up of perpetrators of sexual violence against minors whose legal proceedings were dealt with at the Ziguinchor High Court. The data were entered into an Excel spreadsheet and then analyzed using Epi Info<sup>TM</sup> 7 software. Results: A total of 106 cases of sexual violence against minors were collected for 113 aggressors and 106 victims. Rape accounted for 66.03% of sexual violence. Male aggressors were 98.23%. Female victims accounted for 95.28%. The average age of the attackers was 32.52 years (±13.68). Offenders over the age of 35 committed the most rape (p = 0.043). The average age of the victims was 12.62 years (±3.42). Victims aged ten and over (p = 0.015) and who had a low level of education (p = 0.016) were more exposed to rape. The assault took place during the day (65.71%) and at the home of the aggressor (62.26%). Victims knew their attackers (84.47%). Victims were assaulted more than once by the same assailant (40.57%). Those aged 10 years and over (p = 0.0037) and who knew their attackers (p = 0.014) were more at risk of being repeatedly sexually abused. Conclusion: In Senegal, sexual violence against minors is perpetrated by young adult men, single, with little or no education and exercising low-income professions. Rape is the type of aggression preferred by perpetrators, most of whom were known to their victims. The policy to fight sexual violence against children must integrate sex education at school and community level, public awareness, monitoring of child sex offenders and possibly, their medico-psychological care. 展开更多
关键词 Sexual Violence minors Aggressor Casamance
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The Protection of Right of Minors to Express Their Opinions in Family Litigations
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作者 刘敏 CHEN Feng(Translated) 《The Journal of Human Rights》 2023年第6期1299-1318,共20页
The right of minors to express their opinions in family litigations refers to minors,who have a certain degree of mental capacity and assertiveness,having the right to express their opinions on the arrangements or dec... The right of minors to express their opinions in family litigations refers to minors,who have a certain degree of mental capacity and assertiveness,having the right to express their opinions on the arrangements or decisions related to themselves when the courts handle familial litigation cases involving their interests,and to request the courts hear their opinions.In essence,the right of minors to express their opinions in family litigations belongs to the basic procedural rights of minors as well as judicial beneficiary rights.As for the protection of the right of minors to express their opinions in family litigations,recognizing the status of minors as independent subjects of rights is the logical premise,the procedural guarantee for the rights of the substantive parties involved is the direct cause,and ensuring the best interests of children is the fundamental reason.In order to protect the right of minors to express their opinions in family litigations,China should standardize the mechanisms for judges to hear the opinions of minors directly,improve the mechanisms for family investigators,and establish mechanisms for representing the interests of minors. 展开更多
关键词 family litigations the right of minors to express their opinions procedural guarantee ensuring the best interests of minors
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Serum Zinc and Copper Level in Juvenile Idiopathic Arthritis (JIA) Patients and Its Correlation with Disease Duration-A Tertiary Hospital Study
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作者 Mohammad Imnul Islam Mujammel Haque +4 位作者 Tanzida Sultana Mousumi Ahmed Mohammed Mahbubul Islam Kamrul Laila Manik Kumar Talukder 《Open Journal of Rheumatology and Autoimmune Diseases》 2024年第2期60-68,共9页
Background: Juvenile Idiopathic Arthritis (JIA) is the most prevalent rheumatic disease in children. It is associated with abnormal levels of serum zinc (Zn) and copper (Cu) as during inflammation serum copper concent... Background: Juvenile Idiopathic Arthritis (JIA) is the most prevalent rheumatic disease in children. It is associated with abnormal levels of serum zinc (Zn) and copper (Cu) as during inflammation serum copper concentration increases and zinc decreases. Objective: To assess the serum Zn and Cu levels in different sub-types of JIA patients and their correlation with the disease duration. Methods: This cross-sectional study was conducted over twelve months at the Pediatric Rheumatology Division, Department of Paediatrics, Bangabandhu Sheikh Mujib Medical University. Sixty-nine JIA cases that fulfilled the International League of Association for Rheumatology (ILAR) criteria were taken as cases and age and sex-matched healthy children were considered as controls. The serum Zn and Cu tests were done using the spectrophotometric method with INDIKO PLUS Drug Analyzer. Data were recorded in a pre-designed questionnaire. Data were checked, verified and analyzed manually where continuous variables were analyzed using unpaired t-test and categorical variables using the ANOVA test. Pearson’s correlation coefficient test was used to see the correlation of serum zinc and copper levels with disease duration. Results: Boys were predominant in both case and control groups, with the majority within the 10 to 16-year-age group. Enthesitis-related arthritis (ERA) was the most common subtype followed by sJIA, Oligo JIA, Poly JIA (RF-) and unclassified subtypes. Disease duration was found less than 12 months in 30.4% of JIA patients. Serum analysis revealed a statistically significant reduction in mean zinc levels and increased copper levels in JIA patients compared to controls. This study observed a negative correlation between serum zinc levels and disease duration, whereas serum copper levels exhibited a positive correlation with disease duration. Conclusion: In conclusion, this study revealed that JIA patients exhibit alterations in serum zinc and copper levels. Serum copper levels showed a positive correlation and serum zinc levels showed a negative correlation with the duration of the disease. 展开更多
关键词 Copper juvenile Idiopathic Arthritis ZINC
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Juvenile Xanthogranuloma: A Case Report with Literature Review
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作者 Ayad Ghanam Manal Azizi +3 位作者 Hind Zahiri Aziza El Ouali Abdeladim Babakhouya Maria Rkain 《Open Journal of Pediatrics》 2024年第3期531-535,共5页
Juvenile xanthogranuloma (XGJ) is the most common form of non-Langerhansian histiocytosis. We report a pediatric case of multiple XGJ without visceral involvement in a 6-month-old female infant who was hospitalized wi... Juvenile xanthogranuloma (XGJ) is the most common form of non-Langerhansian histiocytosis. We report a pediatric case of multiple XGJ without visceral involvement in a 6-month-old female infant who was hospitalized with disseminated congenital skin nodules, of firm consistency, of variable diameter ranging from a few millimetres to 1 cm, involving the face, scalp, trunk and limbs. There was no mucosal localization. The remainder of the somatic examination was unremarkable. The diagnosis of disseminated XGJ was confirmed by skin biopsy without visceral or systemic involvement. Therapeutic abstention was recommended. This observation underlines the fact that XGJ is a rare clinical entity that should not be overlooked when faced with congenital skin nodules. 展开更多
关键词 Cutaneous Nodules juvenile Xanthogranuloma CHILD
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Fruit Powder of Tetrapleura tetraptera in Local Feed on Some Zootechnical Performances of Juveniles of Clarias gariepinus in Concrete Tank
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作者 Ngouana Tadjong Ruben Abdoulaye Abdoulaye +1 位作者 Kana Jean Raphaël Téguia Alexis 《Open Journal of Animal Sciences》 2024年第2期56-69,共14页
This study focused on the supplementation of four-sided spice fruit powder (Tetrapleura tetraptera) on some zootechnical performances of juveniles of Clarias gariepinus and was carried out from February 14 to July 20 ... This study focused on the supplementation of four-sided spice fruit powder (Tetrapleura tetraptera) on some zootechnical performances of juveniles of Clarias gariepinus and was carried out from February 14 to July 20 at the Massoma Fish Farm of Bojongo Mbeidi located in the Littoral Region, Department of Wouri, Douala IV district. The farm benefits from a climate favorable to aquaculture activity. For this purpose, five (5) treatments were tested including T<sub>0+</sub> (imported feed), T<sub>0-</sub>, T<sub>0.3</sub>, T<sub>0.4</sub>, and T<sub>0.5</sub> respectively for the treatments with 0% supplemented food;0.3%;0.4% and 0.5% of Tetrapleura tetraptera powder. A total of 450 Clarias gariepinus fry with an initial average weight of 7 ± 1.5 g, were distributed in happas of 0.49 m<sup>2</sup> each placed in Triplicate in a completely randomized device. Four isoprotein foods with 38% crude protein were formulated to feed these fry at 7% of their biomass per day for 15 days then to their fullness until the end of the experiment. Intermediate fishing was carried out every fortnight. 75 days later, the results recorded show that the highest average survival rate (96.44% ± 3.5%) was recorded with the subjects fed feed supplemented with 0.4% T. tetraptera powder. The average weight (120.93 ± 67.20), weight gain (113.93 ± 67.20), specific growth rate (3.64 ± 0.79% g/d) and total lengths and standard (26.43 ± 1.9 and 23.66 ± 1.76) the highest were recorded with the T<sub>0+</sub> treatment (imported feed). The highest conditioning factor K (2.14 ± 0.15) was recorded with the treatment supplemented with 0.4% T. tetraptera. The lowest conversion ratio (1.28) was recorded with the treatment fed with imported blue crown food (T<sub>0+</sub>). Furthermore, the lowest production cost was recorded with the treatment supplemented with 0.4% T. tetraptera. It appears from this study that the juveniles of C. gariepinus better value the feed substituted with 0.4% of the powder of four sides (Tetrapleura tetraptera). 展开更多
关键词 Tetrapleura tetraptera Local Feed Zootechnical Performance juvenile of Clarias gariepinus
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Systematic review and network meta-analysis of different nonsteroidal anti-inflammatory drugs for juvenile idiopathic arthritis
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作者 Tao Zeng Jian-Zhong Ye +1 位作者 Hui Qin Qian-Qian Xu 《World Journal of Clinical Cases》 SCIE 2024年第12期2056-2064,共9页
BACKGROUND Various non-steroidal anti-inflammatory drugs(NSAIDs)have been used for juvenile idiopathic arthritis(JIA).However,the optimal method for JIA has not yet been developed.AIM To perform a systematic review an... BACKGROUND Various non-steroidal anti-inflammatory drugs(NSAIDs)have been used for juvenile idiopathic arthritis(JIA).However,the optimal method for JIA has not yet been developed.AIM To perform a systematic review and network meta-analysis to determine the optimal instructions.METHODS We searched for randomized controlled trials(RCTs)from PubMed,EMBASE,Google Scholar,CNKI,and Wanfang without restriction for publication date or language at August,2023.Any RCTs that comparing the effectiveness of NSAIDs with each other or placebo for JIA were included in this network meta-analysis.The surface under the cumulative ranking curve(SUCRA)analysis was used to rank the treatments.P value less than 0.05 was identified as statistically significant.RESULTS We included 8 RCTs(1127 patients)comparing 8 different instructions including meloxicam(0.125 qd and 0.250 qd),Celecoxib(3 mg/kg bid and 6 mg/kg bid),piroxicam,Naproxen(5.0 mg/kg/d,7.5 mg/kg/d and 12.5 mg/kg/d),inuprofen(30-40 mg/kg/d),Aspirin(60-80 mg/kg/d,75 mg/kg/d,and 55 mg/kg/d),Tolmetin(15 mg/kg/d),Rofecoxib,and placebo.There were no significant differences between any two NSAIDs regarding ACR Pedi 30 response.The SUCRA shows that celecoxib(6 mg/kg bid)ranked first(SUCRA,88.9%),rofecoxib ranked second(SUCRA,68.1%),Celecoxib(3 mg/kg bid)ranked third(SUCRA,51.0%).There were no significant differences between any two NSAIDs regarding adverse events.The SUCRA shows that placebo ranked first(SUCRA,88.2%),piroxicam ranked second(SUCRA,60.5%),rofecoxib(0.6 mg/kg qd)ranked third(SUCRA,56.1%),meloxicam(0.125 mg/kg qd)ranked fourth(SUCRA,56.1%),and rofecoxib(0.3 mg/kg qd)ranked fifth(SUCRA,56.1%).CONCLUSION In summary,celecoxib(6 mg/kg bid)was found to be the most effective NSAID for treating JIA.Rofecoxib,piroxicam,and meloxicam may be safer options,but further research is needed to confirm these findings in larger trials with higher quality studies. 展开更多
关键词 Non-steroidal anti-inflammatory drugs juvenile idiopathic arthritis Network meta-analysis Systematic review
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Predictive modeling for postoperative delirium in elderly patients with abdominal malignancies using synthetic minority oversampling technique
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作者 Wen-Jing Hu Gang Bai +6 位作者 Yan Wang Dong-Mei Hong Jin-Hua Jiang Jia-Xun Li Yin Hua Xin-Yu Wang Ying Chen 《World Journal of Gastrointestinal Oncology》 SCIE 2024年第4期1227-1235,共9页
BACKGROUND Postoperative delirium,particularly prevalent in elderly patients after abdominal cancer surgery,presents significant challenges in clinical management.AIM To develop a synthetic minority oversampling techn... BACKGROUND Postoperative delirium,particularly prevalent in elderly patients after abdominal cancer surgery,presents significant challenges in clinical management.AIM To develop a synthetic minority oversampling technique(SMOTE)-based model for predicting postoperative delirium in elderly abdominal cancer patients.METHODS In this retrospective cohort study,we analyzed data from 611 elderly patients who underwent abdominal malignant tumor surgery at our hospital between September 2020 and October 2022.The incidence of postoperative delirium was recorded for 7 d post-surgery.Patients were divided into delirium and non-delirium groups based on the occurrence of postoperative delirium or not.A multivariate logistic regression model was used to identify risk factors and develop a predictive model for postoperative delirium.The SMOTE technique was applied to enhance the model by oversampling the delirium cases.The model’s predictive accuracy was then validated.RESULTS In our study involving 611 elderly patients with abdominal malignant tumors,multivariate logistic regression analysis identified significant risk factors for postoperative delirium.These included the Charlson comorbidity index,American Society of Anesthesiologists classification,history of cerebrovascular disease,surgical duration,perioperative blood transfusion,and postoperative pain score.The incidence rate of postoperative delirium in our study was 22.91%.The original predictive model(P1)exhibited an area under the receiver operating characteristic curve of 0.862.In comparison,the SMOTE-based logistic early warning model(P2),which utilized the SMOTE oversampling algorithm,showed a slightly lower but comparable area under the curve of 0.856,suggesting no significant difference in performance between the two predictive approaches.CONCLUSION This study confirms that the SMOTE-enhanced predictive model for postoperative delirium in elderly abdominal tumor patients shows performance equivalent to that of traditional methods,effectively addressing data imbalance. 展开更多
关键词 Elderly patients Abdominal cancer Postoperative delirium Synthetic minority oversampling technique Predictive modeling Surgical outcomes
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Cardiovascular diseases in European ethnic minorities: Beyond the traditional cardiovascular risk factors
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作者 Mohamed Bamoshmoosh 《World Journal of Cardiology》 2024年第3期98-103,共6页
This editorial is intended to be a reflection on cardiovascular disease(CVD)burden in European ethnic minorities.In some European countries,ethnic minority realities,due to their recent appearance,are still to be stud... This editorial is intended to be a reflection on cardiovascular disease(CVD)burden in European ethnic minorities.In some European countries,ethnic minority realities,due to their recent appearance,are still to be studied in depth.The experience of several European countries,where the migration processes started earlier,even more than a century ago,can help by being an example.Many studies have shown that major differences in CVD burden exist not only between countries,but also within the same country when considering different social strata and ethnic groups.The CV risk factors underlying heart disease have been well established.Important epidemiological studies have helped us understand that the underlying causes of heart disease as well as the behaviors that can help prevent them are the same.We are now well aware that CVD should be treated by considering a holistic approach.This is why the social determinants(SDs)of health that may worsen the disease burden or that,vice versa,may improve the treatment,and even more significantly,the prognosis of a patient’s illness should be taken into consideration.For ethnic minority patients,this holistic,hermeneutic approach is of importance.Several SDs of health that influence CVDs have been identified but their relevance for the health of ethnic minorities has not yet been clearly defined.In some European countries,most ethnic minorities are largely also religious minorities.Only a few studies have evaluated the role of religion,which is an important SD that affects the probability of having CV risk factors and diseases.Adolescents,particularly those belonging to the second generation,seem to be the weak link.If we believe that these young people are really citizens of their country of birth,then a way of recognizing their belonging to the community starts from a will to better understand their condition,in order to assist them while they grow physically and mentally.Thinking about safeguarding the health of this population should be more than a health task,rather a goal of social justice. 展开更多
关键词 Cardiovascular diseases Cardiovascular risk factors European ethnic minorities Social determinants of health
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4-连通P0-Minor-Free图的特征
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作者 魏林嵩 杨卫华 《应用数学进展》 2024年第5期2445-2450,共6页
设H和G是两个图,如果图H可以通过从图G的一个子图中收缩边然后删除产生的环和平行边得到,我们就把图H叫做图G的一个minor。如果图G没有同构于图H的minor,我们称图G为H-minor-free图。图论中很多猜想都与H-minor-free图有关,例如Hadwige... 设H和G是两个图,如果图H可以通过从图G的一个子图中收缩边然后删除产生的环和平行边得到,我们就把图H叫做图G的一个minor。如果图G没有同构于图H的minor,我们称图G为H-minor-free图。图论中很多猜想都与H-minor-free图有关,例如Hadwiger猜想和Tutte 4-流猜想等。为了推动这些猜想的解决,我们目前非常关注Petersen-minor-free图的结构。由于它们都是15条边的3-连通图,直接刻画起来比较困难。因此为了刻画Petersen-minor-free图,许多学者尝试对每个边数小于15的3-连通图进行刻画去接近Petersen-minor-free图。记P0为Petersen收缩两条完美匹配边和一条非完美匹配边得到的子图基础上添加一条边得到的13条边的图。本文下面将给出完整的4-连通P0-minor-free图的刻画。 展开更多
关键词 minor 四连通图 PETERSEN图
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Systemic juvenile idiopathic arthritis–associated lung disease: A retrospective cohort study
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作者 Konstantin E Belozerov Natalia M Solomatina +2 位作者 Eugenia A Isupova Alla A Kuznetsova Mikhail M Kostik 《World Journal of Clinical Pediatrics》 2024年第1期73-83,共11页
BACKGROUND Lung damage in systemic juvenile arthritis(sJIA)is one of the contemporary topics in pediatric rheumatology.Several previous studies showed the severe course and fatal outcomes in some patients.The informat... BACKGROUND Lung damage in systemic juvenile arthritis(sJIA)is one of the contemporary topics in pediatric rheumatology.Several previous studies showed the severe course and fatal outcomes in some patients.The information about interstitial lung disease(ILD)in the sJIA is scarce and limited to a total of 100 cases.AIM To describe the features of sJIA patients with ILD in detail.METHODS In the present retrospective cohort study,information about 5 patients less than 18-years-old with sJIA and ILD were included.The diagnosis of sJIA was made according to the current 2004 and new provisional International League of Associations for Rheumatology criteria 2019.ILD was diagnosed with chest computed tomography with the exclusion of other possible reasons for concurrent lung involvement.Macrophage activation syndrome(MAS)was diagnosed with HLH-2004 and 2016 EULAR/ACR/PRINTO Classification Criteria and hScores were calculated during the lung involvement.RESULTS The onset age of sJIA ranged from 1 year to 10 years.The time interval before ILD ranged from 1 mo to 3 years.The disease course was characterized by the prevalence of the systemic features above articular involvement,intensive rash(100%),persistent and very active MAS(hScore range:194-220)with transaminitis(100%),and respiratory symptoms(100%).Only 3 patients(60%)developed a clubbing phenomenon.All patients(100%)had pleural effusion and 4 patients(80%)had pericardial effusion at the disease onset.Two patients(40%)developed pulmonary arterial hypertension.Infusion-related reactions to tocilizumab were observed in 3(60%)of the patients.One patient with trisomy 21 had a fatal disease course.Half of the remaining patients had sJIA remission and 2 patients had improvement.Lung disease improved in 3 patients(75%),but 1 of them had initial deterioration of lung involvement.One patient who has not achieved the sJIA remission had the progressed course of ILD.No cases of hyper-eosinophilia were noted.Four patients(80%)received canakinumab and one(20%)tocilizumab at the last follow-up visit.CONCLUSION ILD is a severe life-threatening complication of sJIA that may affect children of different ages with different time intervals since the disease onset.Extensive rash,serositis(especially pleuritis),full-blown MAS with transaminitis,lymphopenia,trisomy 21,eosinophilia,and biologic infusion reaction are the main predictors of ILD.The following studies are needed to find the predictors,pathogenesis,and treatment options,for preventing and treating the ILD in sJIA patients. 展开更多
关键词 Systemic juvenile arthritis Interstitial lung disease CANAKINUMAB TOCILIZUMAB INTERLEUKIN-6 INTERLEUKIN-1
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Spiritual Forests—A Nature Conservation Model of Ethnic Minority Communities in Central Viet Nam
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作者 Tran Huu Nghi Nguyen Quynh Thu 《Open Journal of Forestry》 2024年第1期74-86,共13页
This paper aims to analyze and evaluate a model of forest conservation and management of ethnic minority (or indigenous) people in central Vietnam, often referred to as the spiritual forest. These forests, called sacr... This paper aims to analyze and evaluate a model of forest conservation and management of ethnic minority (or indigenous) people in central Vietnam, often referred to as the spiritual forest. These forests, called sacred forest or ghost forests by the ethnic minority people in Thua Thien Hue province, have existed for a long time among forest residents. However, they have recently declined, both in quality and quantity, due to various factors, including changes in society, economy, environment, and perception, among other reasons. Based on research conducted in A Luoi district, Thua Thien Hue province with household interviews, group discussions, and field surveys, we find that spiritual forest retains religious and human significance. They are also often among the last remaining natural forests left due to deforestation by human activities. The research results indicate challenges that conservation of spiritual forest may face, while giving recommendations derived from communities for sustainable forest development and conservation in the region. 展开更多
关键词 Forest Conservation Ethnic minority Spiritual Forest
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海岸凤尾蕨(Pteris minor)的地理分布格局及保护价值分析
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作者 郭芮 贺丹 +4 位作者 黄航 于靖 徐诗涛 严岳鸿 杨东梅 《热带作物学报》 CSCD 北大核心 2023年第1期208-214,共7页
海岸凤尾蕨是海岸带少有的蕨类植物之一。由于其植株形态和傅氏凤尾蕨相似,因长期被误定为傅氏凤尾蕨而缺乏关注。其实,二者在生境、植株形态、孢子形态及染色体倍性上有明显区别。所以,海岸凤尾蕨由傅氏凤尾蕨的变种提升为种。为厘清... 海岸凤尾蕨是海岸带少有的蕨类植物之一。由于其植株形态和傅氏凤尾蕨相似,因长期被误定为傅氏凤尾蕨而缺乏关注。其实,二者在生境、植株形态、孢子形态及染色体倍性上有明显区别。所以,海岸凤尾蕨由傅氏凤尾蕨的变种提升为种。为厘清海岸凤尾蕨的分布区域和生存现状,通过整理前人的采集记录和研究结果,结合野外考察,使用Arc-GIS 10.7软件构建海岸凤尾蕨不同范围的地理分布信息图,并依据IUCN 3.1的标准,对其保护价值进行评估。研究结果显示:(1)从世界地理分布格局来看,海岸凤尾蕨主要分布在亚洲;亚洲主要分布在中国、日本和菲律宾;中国主要分布在浙江、福建、澳门、香港和台湾;日本主要分布在琉球群岛;菲律宾主要分布在北部岛屿。(2)根据IUCN 3.1标准,海岸凤尾蕨的保护等级暂时定为近危(NT)。从目前的数据来看,海岸凤尾蕨的分布范围狭窄,其生境容易受到人类活动的干扰,却长期缺乏保护。因此,最后提出相应保护建议。 展开更多
关键词 海岸凤尾蕨 地理分布格局 保护价值
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Familial Lateral Sclerosis with Juvenile Onset: About 3 Cases and Review of the Literature
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作者 Camara Mamady Barry Souleymane Djigué +12 位作者 Dore Male Toure Mohamed Lamine Diallo Mohamed Tafsir Toure Laïla Youla Seny Konate Ibrahimasory Barry Louceny Fatoumata Camara Mohamed Salif Camara Idrissa Doumbouya Idrissa Djibo Hamani Bachir Conde Mohamed Lamine Cisse Fodé Abass 《Journal of Biosciences and Medicines》 2023年第10期55-62,共8页
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease deadly. In Africa, little data exists on this condition and the form familial is the most common with a younger age of onset. Our observations relate ... Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease deadly. In Africa, little data exists on this condition and the form familial is the most common with a younger age of onset. Our observations relate to three brothers, born from a consanguineous marriage. The diagnosis of amyotrophic lateral sclerosis was certain placed in all patients according to the criteria of Awaji. The average age of patients was 16.66 years, and the average age of onset of symptoms was 10.33 years old. The female gender was the most represented with a sex ratio of 0.5. Our patients benefited from rilusole, vitamin D and physiotherapy. A only patient presented with dysphagia. However, no cases have been observed at this day. 展开更多
关键词 ALS FAMILIAL juvenilE
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Turning into a “Godparent”: How adult volunteers negotiate their personal life to become a mentor for “Unaccompanied Refugee Minors”
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作者 Eberhard Raithelhuber 《Social Work and Social Welfare》 2019年第1期23-36,共14页
This article looks into how volunteers deal with their biographies and social embeddedness to make sense of their engagement in mentoring before they are matched. It draws on a qualitative investigation on a community... This article looks into how volunteers deal with their biographies and social embeddedness to make sense of their engagement in mentoring before they are matched. It draws on a qualitative investigation on a community-based pilot youth mentoring program for “unaccompanied refugee minors” in Austria. This article reveals how already trained, local adults actively relate to “family,”“migration” and “previous activities” in their meaning-making. It shows how they negotiate their personal life and existing relationships in the process of turning into a future “godparent.” The discussion of findings against the state of the art leads the way to two heuristic claims: firstly, the study provides grounded arguments for an extension of the conventional mentoring concept on the side of the mentor. Secondly, for a more relational and processual approach towards the mentors’ side, both biographical and social network dimensions need to be integrated in methods and designs of youth mentoring research. 展开更多
关键词 youth MENTORING programs voluntary mentors unaccompanied REFUGEE minors PERSONAL LIFE social networks BIOGRAPHY MENTORING as a concept
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A minor emphasis on the outbreak of cutaneous leishmaniasis after devastating earthquakes in Turkey
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作者 Ilknur Nihal Ardic Nurittin Ardic 《Asian Pacific Journal of Tropical Medicine》 SCIE CAS 2023年第3期97-98,共2页
Leishmaniasis is a serious parasitic disease caused by Leishmania species transmitted by the bite of sandflies. This disease is also an important public health problem. Clinical manifestations can be classified as cut... Leishmaniasis is a serious parasitic disease caused by Leishmania species transmitted by the bite of sandflies. This disease is also an important public health problem. Clinical manifestations can be classified as cutaneous, mucocutaneous, and visceral leishmaniasis, depending on the species of parasite and the host’s immune status. Although the cutaneous form is not fatal, it often causes disfiguring scars on the skin[1]. 展开更多
关键词 EARTHQUAKES minor problem.
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Thalidomide Is an Adjunct Therapy for the Refractory Systemic Juvenile Idiopathic Arthritis Patients in a Tertiary Hospital Study
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作者 Md. Taiyabur Rahman Mujammel Haque +4 位作者 Farhana Faria Mohammed Mahbubul Islam Manik Kumar Talukder Mohammad Imnul Islam Shahana Akhter Rahman 《Open Journal of Rheumatology and Autoimmune Diseases》 2023年第2期51-63,共13页
Background: Systemic JIA (sJIA) is one of the subtypes of JIA, which is most difficult to treat among all JIA cases. About 50% of sJIA cases did not respond to traditional disease modifying anti-rheumatic drugs (DMAR... Background: Systemic JIA (sJIA) is one of the subtypes of JIA, which is most difficult to treat among all JIA cases. About 50% of sJIA cases did not respond to traditional disease modifying anti-rheumatic drugs (DMARDs)—metho-trexate (MTX). Thalidomide is an immunomodulating and anti-inflammatory drug that induces sustained improvement of refractory sJIA cases. Objectives: To evaluate the efficacy of thalidomide in refractory sJIA patients. Methods: This was a prospective interventional study carried out in the Paediatric Rheumatology and Immunology follow-up clinic run by the Department of Pediatrics, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka from January 2019 to July 2020. Twenty-five sJIA patients who were refractory to conventional DMARDs were included in this study. These patients were prescribed thalidomide at a dose of 3 - 5 mg/kg/day for six months and efficacy was assessed by using juvenile arthritis disease activity score (JADAS 27) at 12<sup>th</sup> and 24<sup>th</sup> weeks of treatment. Result: Active joint counts and ESR improvement were observed in 90.69%, 97.67% and 69.84%, 100% of sJIA patients respectively at 12<sup>th</sup> and 24<sup>th</sup> weeks of treatment. Improvement of physicians and parent global assessment of VAS were 77.56%, 97.43% and 70.62% and 96.04% respectively at 12<sup>th</sup> and 24<sup>th</sup> weeks of treatment. Improvement of the total score of JADAS-27 was 77.51% at 12th week and 97.52% at 24<sup>th</sup> of week follow-up which was statistically significant. Somnolence, constipation and paresthesia were found as common adverse effect in this study. Conclusion: Efficacy of thalidomide was assessed by JADAS 27 criteria showed significant improvement in refractory sJIA patients in this study. It may be concluded that Thalidomide is safe and effective as an adjunct therapy of refractory sJIA patients. 展开更多
关键词 juvenile Idiopathic Arthritis THALIDOMIDE Refractory sJIA
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Risk and benefit from clinical trials in minors:Making the case for transparent and consistent publications
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作者 Andreas Dirk Henschel Lillian Geza Rothenberger +3 位作者 Dominik Schrey Joachim Gerβ Georg Hempel Joachim Boos 《Open Journal of Pediatrics》 2013年第2期151-164,共14页
Rationale, aim and objectives: The European (EU) regulation on medicinal products for pediatric use (EC 1901/2006), which became effective in 2007, aimed to stimulate the clinical testing of medications in minors in o... Rationale, aim and objectives: The European (EU) regulation on medicinal products for pediatric use (EC 1901/2006), which became effective in 2007, aimed to stimulate the clinical testing of medications in minors in order to reduce off-label use. In consequence, the number of minors taking part in randomized controlled clinical trials (RCTs) is likely to increase. Clinical trials in minors require a complex methodological design, a careful consideration of risks and benefits and a high level of ethical reflection. Unfortunately, as to the quality of clinical trials and their publications in minors little is known. Therefore, we assessed published reports of randomized, controlled clinical trials in minors, focusing on a common disease (asthma) and a defined spectrum of lifethreatening diseases (malignant diseases). Method: In an exploratory design, we scanned the publications for methodological aspects as well as indicators of ethical soundness, e.g., statements that informed consent had been obtained before the start of the trial or that a Data and Safety Monitoring Board ensured the patients’ safety during the trial. We also looked for passages reflecting the debate on equipoise or other forms of weighing risks and benefits. Results: We found that many of these aspects, which according to the scientific literature and generally acknowledged guidelines are essential to ensure good-quality trials and trial reports, were not considered in the publications analyzed. Conclusion: Therefore, we call for a more transparent and consistent presentation of the trials, especially of safety aspects, relying on a more critical and transparent ethical reflection. 展开更多
关键词 Clinical Trials minors SIGN CONSORT ETHICS
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Achievements Outstanding In Protecting Minors——Report on enforcement of Law on the Protection of Minors (excerpts)
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作者 GU XIULIAN Vice-Chairperson of the NPC Standing Committee, China. 《The Journal of Human Rights》 2003年第6期6-9,共4页
The Law of the People's Republic of China on the Protection of Minors and the Law ofthe People's Republic of China on the Prevention of Juvenile Crimes were passed on September 4, 1991 and June 28,1999 and cam... The Law of the People's Republic of China on the Protection of Minors and the Law ofthe People's Republic of China on the Prevention of Juvenile Crimes were passed on September 4, 1991 and June 28,1999 and came into force on January 1, 1992 and November 1, 1999. Over the past decades, China has scoredoutstanding achievements in implementing the two laws. In order to strengthen supervision of the implementationof the two laws and better protect the lawful rights and interests of the under-aged, the National People's CongressStanding Committee set up a Law Enforcement Check Group in July 2003, which carried out a nationwidecheck of the implementation of the two laws. On August 25, NPC Vice-Chairperson Gu Xiulian reported on theresult of the check to the fourth meeting of the Tenth NPC standing committee. She described the generalsituation in the implementation of the two laws as 'good' and also identified some problems and put forwardsome recommendations with regard to the enforcement and implementation of the two laws.The following are the excerpts of the report: 展开更多
关键词 of for Pr on excerpts Achievements Outstanding In Protecting minors Report on enforcement of Law on the Protection of minors
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Prolapsed Juvenile Polyp of the Anus in 2 Cases
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作者 Mohamed Lamine Sadou Sacko Balla Keita +6 位作者 Thierno Saidou Barry Mory Sangare Mamadou Madiou Barry Moussa Conde Seydou Keita Salif Mariértou Sylla Daniel Agbo-Panzo 《Open Journal of Pediatrics》 2023年第6期785-790,共6页
Introduction :Rectal polyps are well-circumscribed, sessile or pedunculated formations that develop on the digestive mucosa. Juvenile polyps are seen in 4% - 12% of cases during pediatric colonoscopies. In children, r... Introduction :Rectal polyps are well-circumscribed, sessile or pedunculated formations that develop on the digestive mucosa. Juvenile polyps are seen in 4% - 12% of cases during pediatric colonoscopies. In children, rectal bleeding is a frequent warning sign, often a recurrent bleed with no impact on general condition. Diagnosis is based on clinical, imaging and digestive investigations, but anatomopathological examination remains the only means of confirmation. There are a number of treatment options, ranging from abstention to surgical excision. We report two (2) cases of isolated hemorrhagic juvenile polyp prolapsed to the anus in order to analyze the diagnostic and therapeutic features of this pathology. Patients and observations: A 7-year-old female patient presented to the pediatric emergency department of the Donka National Hospital with a hemorrhagic anal mass. On clinical examination, the patient was found to be in satisfactory general condition, with a hemorrhagic pedicle mass prolapsed to the anus. The mass was removed under general anesthesia. Postoperative management was straightforward. Conclusion: Juvenile polyps are the most common proctological condition in this age group. Clinical examination must be meticulous, as certain signs may point to a particular pathology. Colonoscopy is the diagnostic test of choice, and can also be used as a therapeutic tool. 展开更多
关键词 POLYP juvenilE PROLAPSE CHILD
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