The compatibility of Chinese herbs is the focus and the difficulty in traditional Chinese medicine research,and it has an important guiding role for clinical medicine.Some scholars believe that the Fuzi(Radix Aconiti ...The compatibility of Chinese herbs is the focus and the difficulty in traditional Chinese medicine research,and it has an important guiding role for clinical medicine.Some scholars believe that the Fuzi(Radix Aconiti Lateralis Preparata,FZ)compatibility with Tubeimu(Rhizoma Bolbostemmatis,TBM)/Gualou(Trichosanthes kirilowii Maxim,GL)does not meet the Chinese medicine theory of“eighteen incompatibilities”.However,this combination has been used many times in many clinical medications.This study reviewed the research progress of pharmacological effects of FZ,and FZ compatibility with TBM/GL,in order to correctly understand and apply the“eighteen incompatibilities”drugs,and provide a reference for further exploration of the combined application in clinical treatment.展开更多
Ribosome-inactivating proteins in Trichosanthes kirilowii having high anti-HIV activity can be efficiently obtained by culturing Trichosanthes kirilowii hairy root. A hairy root line from Trichosanthes kirilowii was ...Ribosome-inactivating proteins in Trichosanthes kirilowii having high anti-HIV activity can be efficiently obtained by culturing Trichosanthes kirilowii hairy root. A hairy root line from Trichosanthes kirilowii was cultivated in flasks and in a 5-L bioreactor. The results show that a logistic equation can be used to describe the relationship between the hairy root biomass and the culture time. The medium conductivity decrease is linearly related to the biomass amount. In the suspension culture, the hairy root growth is closely related to the nutrient consumption. The biomass to nitrate yield is 0.352 g/mmol. The growth rate of the hairy root in the bioreactor is higher than that in the flasks, and after a 12-day culture its growth rate enters a high-speed period when the growth rate is 0.738 g/( L·d).展开更多
文摘The compatibility of Chinese herbs is the focus and the difficulty in traditional Chinese medicine research,and it has an important guiding role for clinical medicine.Some scholars believe that the Fuzi(Radix Aconiti Lateralis Preparata,FZ)compatibility with Tubeimu(Rhizoma Bolbostemmatis,TBM)/Gualou(Trichosanthes kirilowii Maxim,GL)does not meet the Chinese medicine theory of“eighteen incompatibilities”.However,this combination has been used many times in many clinical medications.This study reviewed the research progress of pharmacological effects of FZ,and FZ compatibility with TBM/GL,in order to correctly understand and apply the“eighteen incompatibilities”drugs,and provide a reference for further exploration of the combined application in clinical treatment.
文摘Ribosome-inactivating proteins in Trichosanthes kirilowii having high anti-HIV activity can be efficiently obtained by culturing Trichosanthes kirilowii hairy root. A hairy root line from Trichosanthes kirilowii was cultivated in flasks and in a 5-L bioreactor. The results show that a logistic equation can be used to describe the relationship between the hairy root biomass and the culture time. The medium conductivity decrease is linearly related to the biomass amount. In the suspension culture, the hairy root growth is closely related to the nutrient consumption. The biomass to nitrate yield is 0.352 g/mmol. The growth rate of the hairy root in the bioreactor is higher than that in the flasks, and after a 12-day culture its growth rate enters a high-speed period when the growth rate is 0.738 g/( L·d).
