AIM To investigate proprioceptive discrepancies in the lower extremity in persons with type 2 diabetes mellitus(T2DM). METHODS In this cross-sectional study, a total of 46 older persons were divided into a T2DM group(...AIM To investigate proprioceptive discrepancies in the lower extremity in persons with type 2 diabetes mellitus(T2DM). METHODS In this cross-sectional study, a total of 46 older persons were divided into a T2DM group(n = 23) and a control group who did not have T2 DM(n = 23). Participants were given a brief warm up with stretching exercises. Diabetic neuropathy scores were collected prior to proprioceptive testing. For proprioceptive testing, participants performed leg extensions to randomized target positions of 15°, 30°, 45, 60° degrees of elevation in the sagittal plane, each target was repeated a total of four times. Subjects were guided to target positions in the absence of visual feedback via auditory cues from a custom JPS application. When the participant entered the target position, they memorized the location of their limb in space and subsequently attempted to relocate this position in space. Proprioceptive errors were measured from the target positioned, target remembered, target repositioned protocol. RESULTS Proprioceptive accuracy was lower in the diabetic groupat all levels of target angle than the control group(P < 0.05). The diabetic group had 46% greater inaccuracy than the control group at all levels of target position. Diabetics also reported greater neuropathy scores than controls in the past 12 mo P < 0.01. CONCLUSION Deficits in lower limb localization and greater diabetic neuropathy scores were identified in this study. Our findings may be associated with deafferentation as peripheral neuropathy is a common complication with the disease. These findings may help to explain the declining balance function in the older persons with T2DM which is also commonly reported.展开更多
Assessing the radiographic features of knee osteoarthritis （OA）, especially joint space narrowing, is important for evaluating disease progression. The purpose of this study was to quantitatively analyze joint space...Assessing the radiographic features of knee osteoarthritis （OA）, especially joint space narrowing, is important for evaluating disease progression. The purpose of this study was to quantitatively analyze joint space narrowing by measuring 2 new variables： the average joint space width （aJSW） and the articulate angle （AA） on X-ray films, and to evaluate the relationship between the 2 variables, knee function and OA symptoms. Methods Using the web-based radiology viewer （Cedara I-ReachTM 4.1.1）, we measured the 2 variables in 50 knees of 41 patients with knee OA participating in the Shanghai OA Study. We also evaluated the Kellgren-Lawrence （K-L） grade, the Western Ontario and McMaster Universities OA Index （WOMAC）, and additional questionnaire in OA knees. The study was approved by the ethics committee of Shanghai Ninth People＇s Hospital （No. 2009-28）. Results The aJSW correlated with the K-L grade （r=-0.57, P 〈0.001）, kneeling （r=-0.29, P=0.04）, sitting cross-legged on the floor （r=-0.31, P=0.03）, WOMAC pain （r=-0.31, P=0.03）, WOMAC disability （r=-0.35, P=0.01）, pain while squatting （r=-0.37, P=0.01）, and defecating in a squatting position （r=-0.39, P= 0.01）. The AA correlated with defecating in a squatting position （r=0.29, P=0.05）, WOMAC disability （r=0.30, P=0.04） and K-L grade （r=0.44, P=0.003）. The K-L grade also correlated with pain while squatting （r=-0.40, P=0.005） and defecating in a squatting position （r=-0.34, P=0.02）, WOMAC pain （r=0.30, P=0.04）, and WOMAC disability （r=0.30, P=0.04）. Conclusions The aJSW closely correlated with knee OA symptoms and function scores, and was more sensitive to knee OA related disabilities than K-L grade and the AA. The aJSW could be used as a new variable for knee OA evaluation.展开更多
文摘目的 评价磁共振3D space序列在膝关节半月板放射状撕裂中的诊断价值,提高对此病的影像认识,为临床诊疗提供帮助。方法 回顾性分析29例经关节镜证实的膝关节半月板放射状撕裂患者的磁共振资料;对比常规磁共振2D序列与3D space序列在半月板放射状撕裂病变中的诊断效能,使用Fisher确切概率法对两种方法诊断半月板放射状撕裂的准确率进行比较。结果 3D space序列和常规2D序列诊断半月板放射状撕裂的准确率分别为96.7%(29/30)、80.0%(24/30),3D space序列诊断准确率高于常规2D序列,差异有统计学意义(P<0.05)。结论 3D space序列在半月板放射状撕裂的诊断中具有较高价值,其诊断效能优于2D序列。
基金Supported by The Willamette University Mary Stuart Rogers Science Collaborative Research Program Endowment
文摘AIM To investigate proprioceptive discrepancies in the lower extremity in persons with type 2 diabetes mellitus(T2DM). METHODS In this cross-sectional study, a total of 46 older persons were divided into a T2DM group(n = 23) and a control group who did not have T2 DM(n = 23). Participants were given a brief warm up with stretching exercises. Diabetic neuropathy scores were collected prior to proprioceptive testing. For proprioceptive testing, participants performed leg extensions to randomized target positions of 15°, 30°, 45, 60° degrees of elevation in the sagittal plane, each target was repeated a total of four times. Subjects were guided to target positions in the absence of visual feedback via auditory cues from a custom JPS application. When the participant entered the target position, they memorized the location of their limb in space and subsequently attempted to relocate this position in space. Proprioceptive errors were measured from the target positioned, target remembered, target repositioned protocol. RESULTS Proprioceptive accuracy was lower in the diabetic groupat all levels of target angle than the control group(P < 0.05). The diabetic group had 46% greater inaccuracy than the control group at all levels of target position. Diabetics also reported greater neuropathy scores than controls in the past 12 mo P < 0.01. CONCLUSION Deficits in lower limb localization and greater diabetic neuropathy scores were identified in this study. Our findings may be associated with deafferentation as peripheral neuropathy is a common complication with the disease. These findings may help to explain the declining balance function in the older persons with T2DM which is also commonly reported.
文摘Assessing the radiographic features of knee osteoarthritis （OA）, especially joint space narrowing, is important for evaluating disease progression. The purpose of this study was to quantitatively analyze joint space narrowing by measuring 2 new variables： the average joint space width （aJSW） and the articulate angle （AA） on X-ray films, and to evaluate the relationship between the 2 variables, knee function and OA symptoms. Methods Using the web-based radiology viewer （Cedara I-ReachTM 4.1.1）, we measured the 2 variables in 50 knees of 41 patients with knee OA participating in the Shanghai OA Study. We also evaluated the Kellgren-Lawrence （K-L） grade, the Western Ontario and McMaster Universities OA Index （WOMAC）, and additional questionnaire in OA knees. The study was approved by the ethics committee of Shanghai Ninth People＇s Hospital （No. 2009-28）. Results The aJSW correlated with the K-L grade （r=-0.57, P 〈0.001）, kneeling （r=-0.29, P=0.04）, sitting cross-legged on the floor （r=-0.31, P=0.03）, WOMAC pain （r=-0.31, P=0.03）, WOMAC disability （r=-0.35, P=0.01）, pain while squatting （r=-0.37, P=0.01）, and defecating in a squatting position （r=-0.39, P= 0.01）. The AA correlated with defecating in a squatting position （r=0.29, P=0.05）, WOMAC disability （r=0.30, P=0.04） and K-L grade （r=0.44, P=0.003）. The K-L grade also correlated with pain while squatting （r=-0.40, P=0.005） and defecating in a squatting position （r=-0.34, P=0.02）, WOMAC pain （r=0.30, P=0.04）, and WOMAC disability （r=0.30, P=0.04）. Conclusions The aJSW closely correlated with knee OA symptoms and function scores, and was more sensitive to knee OA related disabilities than K-L grade and the AA. The aJSW could be used as a new variable for knee OA evaluation.
