目的:探讨通络祛痛膏联合塞来昔布治疗风湿瘀阻证膝骨关节炎(knee osteoarthritis,KOA)的效果。方法:选取2021年1—12月徐州市中心医院骨科收治的130例风湿瘀阻证KOA患者。根据简单信封随机法将其分为对照组和观察组,各65例。对照组给...目的:探讨通络祛痛膏联合塞来昔布治疗风湿瘀阻证膝骨关节炎(knee osteoarthritis,KOA)的效果。方法:选取2021年1—12月徐州市中心医院骨科收治的130例风湿瘀阻证KOA患者。根据简单信封随机法将其分为对照组和观察组,各65例。对照组给予塞来昔布胶囊,观察组在对照组基础上给予通络祛痛膏。比较两组治疗前后症状评分、临床疗效及不良反应。结果:治疗后,两组KOA严重性指数(index of severity of osteoarthritis,ISOA)评分低于治疗前,观察组低于对照组,差异有统计学意义(P<0.05)。治疗后,观察组临床疗效优于对照组,总有效率高于对照组,差异有统计学意义(P<0.05)。观察组不良反应发生率略低于对照组,但差异无统计学意义(P>0.05),观察组未出现与中药外敷相关的局部皮肤过敏反应。结论:通络祛痛膏联合塞来昔布治疗KOA,能够缓解症状,且不增加药物相关的不良反应,用药安全性良好。展开更多
目的探究膝骨性关节炎患者病程与患侧踇外翻严重程度的相关性。方法将2011年3月至2017年10月在云南省中医医院骨科住院部(35例)及昆明市中医医院骨科住院部(52例)诊断为踇外翻及同侧KOA并符合纳入标准的87例患者纳入研究。依据KOA分期...目的探究膝骨性关节炎患者病程与患侧踇外翻严重程度的相关性。方法将2011年3月至2017年10月在云南省中医医院骨科住院部(35例)及昆明市中医医院骨科住院部(52例)诊断为踇外翻及同侧KOA并符合纳入标准的87例患者纳入研究。依据KOA分期将87例研究对象分为I期组17例、II期组35例、III期22例、IV期13例;根据正常胫股解剖角得膝内翻组患者33例、膝外翻组患者23例;对比不同KOA分期组及内、外翻2组患者间HVA、IMA、PASA及DASA的差异。结果 4个KOA分期组比较:与I期组、II期组比较III期、IV期组HVA较大,P<0.05;IMA:II期组显著大于I期组,P<0.01,与II期组比较,III期组、IV期组IMA较大,P<0.05; PASA:II期组显著大于I期组,P<0.01,II期组、III期组、IV期组无差异;DASA:II期组显著大于I期组,P<0.01,II期组、III期组、IV期组无差异。膝内翻组与膝外翻组比较:膝内翻组HVA(28.7±2.8) vs (33.5±3.5),平均值显著较小,P<0.01, IMA (12.7±2.5) vs (14.3±2.7)、PASA (10.1±2.5)vs (11.6±2.2)、DASA (11.7±2.1 VS 12.9±2.3)较小,P<0.05。与膝内翻组比较,膝外翻组III、IV期KOA患者比例较高(36.3%vs 56.5%),P<0.05。结论踇外翻与膝骨性关节炎两者之间具有一定的正相关性,而对于膝外翻膝骨性关节炎患者来说,这种相关性更为明显。展开更多
Objective To compare the difference in the effect of modified green dragon swaying its tail needling manipulation and common needling manipulations on the overall rating of pain of patients with knee osteoarthritis, a...Objective To compare the difference in the effect of modified green dragon swaying its tail needling manipulation and common needling manipulations on the overall rating of pain of patients with knee osteoarthritis, and to evaluate the advantages of modified green dragon swaying its tail needling manipulation for. Methods Ninety-five patients with knee osteoarthritis were divided into 2 groups according to the random number table method with 48 patients in the modified green dragon swaying its tail group（group special manipulation, SM group for short） and 47 patients in the common acupuncture group（group convention needling, CN group for short）, and different acupuncture manipulations were applied in the two groups. Internationally recognized Simplified Mc Gill Pain Questionnaire（SF-MPQ） scale used for description and measurement of pain was applied to evaluate the pain degree, including pain rating index（PRI）, visnal analogue scale（VAS）and present pain intensity（PPI）. The index of severity for osteoarthritis（ISOA） was adopted for evaluation of clinical efficacy. Results（1） In SM group, the scores of PRI, VAS and PPI were 6.63±4.67, 2.23±1.45 and 0.65±1.32, respectively, after treatment, and in CN group, the scores of PRI, VAS and PPI were 13.32±7.96, 4.34±1.79 and 2.28±1.21, respectively, the scores decreased in the two groups after treatment（all P〈0.05）, and the improvement in SM group was superior to that in CN group（all P〈0.01）.（2） The clinical cure rate in SM group was 52.08%, and the total effective rate was 97.92%, the clinical cure rate in CN group was 25.53%, and the total effective rate was 85.10%. The comparison of clinical cure rate in the two groups showed that P〈0.01. Conclusion The SM group is obviously superior to CN group in the improvement of overall rating of pain of patients. It is indicated that modified green dragon swaying its tail acupuncture therapy can effectively relieve the pain of patients with knee osteoarthritis, which was worthy of popularization and application with definite clinical efficacy展开更多
文摘目的:探讨通络祛痛膏联合塞来昔布治疗风湿瘀阻证膝骨关节炎(knee osteoarthritis,KOA)的效果。方法:选取2021年1—12月徐州市中心医院骨科收治的130例风湿瘀阻证KOA患者。根据简单信封随机法将其分为对照组和观察组,各65例。对照组给予塞来昔布胶囊,观察组在对照组基础上给予通络祛痛膏。比较两组治疗前后症状评分、临床疗效及不良反应。结果:治疗后,两组KOA严重性指数(index of severity of osteoarthritis,ISOA)评分低于治疗前,观察组低于对照组,差异有统计学意义(P<0.05)。治疗后,观察组临床疗效优于对照组,总有效率高于对照组,差异有统计学意义(P<0.05)。观察组不良反应发生率略低于对照组,但差异无统计学意义(P>0.05),观察组未出现与中药外敷相关的局部皮肤过敏反应。结论:通络祛痛膏联合塞来昔布治疗KOA,能够缓解症状,且不增加药物相关的不良反应,用药安全性良好。
文摘目的探究膝骨性关节炎患者病程与患侧踇外翻严重程度的相关性。方法将2011年3月至2017年10月在云南省中医医院骨科住院部(35例)及昆明市中医医院骨科住院部(52例)诊断为踇外翻及同侧KOA并符合纳入标准的87例患者纳入研究。依据KOA分期将87例研究对象分为I期组17例、II期组35例、III期22例、IV期13例;根据正常胫股解剖角得膝内翻组患者33例、膝外翻组患者23例;对比不同KOA分期组及内、外翻2组患者间HVA、IMA、PASA及DASA的差异。结果 4个KOA分期组比较:与I期组、II期组比较III期、IV期组HVA较大,P<0.05;IMA:II期组显著大于I期组,P<0.01,与II期组比较,III期组、IV期组IMA较大,P<0.05; PASA:II期组显著大于I期组,P<0.01,II期组、III期组、IV期组无差异;DASA:II期组显著大于I期组,P<0.01,II期组、III期组、IV期组无差异。膝内翻组与膝外翻组比较:膝内翻组HVA(28.7±2.8) vs (33.5±3.5),平均值显著较小,P<0.01, IMA (12.7±2.5) vs (14.3±2.7)、PASA (10.1±2.5)vs (11.6±2.2)、DASA (11.7±2.1 VS 12.9±2.3)较小,P<0.05。与膝内翻组比较,膝外翻组III、IV期KOA患者比例较高(36.3%vs 56.5%),P<0.05。结论踇外翻与膝骨性关节炎两者之间具有一定的正相关性,而对于膝外翻膝骨性关节炎患者来说,这种相关性更为明显。
基金Supported by Scientific research project of traditional Chinese medicine of Hubei Province in 2014,research project at the academy level of Hubei Provincial Hospital of TCM:JDZX2014Y06
文摘Objective To compare the difference in the effect of modified green dragon swaying its tail needling manipulation and common needling manipulations on the overall rating of pain of patients with knee osteoarthritis, and to evaluate the advantages of modified green dragon swaying its tail needling manipulation for. Methods Ninety-five patients with knee osteoarthritis were divided into 2 groups according to the random number table method with 48 patients in the modified green dragon swaying its tail group（group special manipulation, SM group for short） and 47 patients in the common acupuncture group（group convention needling, CN group for short）, and different acupuncture manipulations were applied in the two groups. Internationally recognized Simplified Mc Gill Pain Questionnaire（SF-MPQ） scale used for description and measurement of pain was applied to evaluate the pain degree, including pain rating index（PRI）, visnal analogue scale（VAS）and present pain intensity（PPI）. The index of severity for osteoarthritis（ISOA） was adopted for evaluation of clinical efficacy. Results（1） In SM group, the scores of PRI, VAS and PPI were 6.63±4.67, 2.23±1.45 and 0.65±1.32, respectively, after treatment, and in CN group, the scores of PRI, VAS and PPI were 13.32±7.96, 4.34±1.79 and 2.28±1.21, respectively, the scores decreased in the two groups after treatment（all P〈0.05）, and the improvement in SM group was superior to that in CN group（all P〈0.01）.（2） The clinical cure rate in SM group was 52.08%, and the total effective rate was 97.92%, the clinical cure rate in CN group was 25.53%, and the total effective rate was 85.10%. The comparison of clinical cure rate in the two groups showed that P〈0.01. Conclusion The SM group is obviously superior to CN group in the improvement of overall rating of pain of patients. It is indicated that modified green dragon swaying its tail acupuncture therapy can effectively relieve the pain of patients with knee osteoarthritis, which was worthy of popularization and application with definite clinical efficacy
