In the current landscape of the COVID-19 pandemic,the utilization of deep learning in medical imaging,especially in chest computed tomography(CT)scan analysis for virus detection,has become increasingly significant.De...In the current landscape of the COVID-19 pandemic,the utilization of deep learning in medical imaging,especially in chest computed tomography(CT)scan analysis for virus detection,has become increasingly significant.Despite its potential,deep learning’s“black box”nature has been a major impediment to its broader acceptance in clinical environments,where transparency in decision-making is imperative.To bridge this gap,our research integrates Explainable AI(XAI)techniques,specifically the Local Interpretable Model-Agnostic Explanations(LIME)method,with advanced deep learning models.This integration forms a sophisticated and transparent framework for COVID-19 identification,enhancing the capability of standard Convolutional Neural Network(CNN)models through transfer learning and data augmentation.Our approach leverages the refined DenseNet201 architecture for superior feature extraction and employs data augmentation strategies to foster robust model generalization.The pivotal element of our methodology is the use of LIME,which demystifies the AI decision-making process,providing clinicians with clear,interpretable insights into the AI’s reasoning.This unique combination of an optimized Deep Neural Network(DNN)with LIME not only elevates the precision in detecting COVID-19 cases but also equips healthcare professionals with a deeper understanding of the diagnostic process.Our method,validated on the SARS-COV-2 CT-Scan dataset,demonstrates exceptional diagnostic accuracy,with performance metrics that reinforce its potential for seamless integration into modern healthcare systems.This innovative approach marks a significant advancement in creating explainable and trustworthy AI tools for medical decisionmaking in the ongoing battle against COVID-19.展开更多
Specific medical data has limitations in that there are not many numbers and it is not standardized.to solve these limitations,it is necessary to study how to efficiently process these limited amounts of data.In this ...Specific medical data has limitations in that there are not many numbers and it is not standardized.to solve these limitations,it is necessary to study how to efficiently process these limited amounts of data.In this paper,deep learning methods for automatically determining cardiovascular diseases are described,and an effective preprocessing method for CT images that can be applied to improve the performance of deep learning was conducted.The cardiac CT images include several parts of the body such as the heart,lungs,spine,and ribs.The preprocessing step proposed in this paper divided CT image data into regions of interest and other regions using K-means clustering and the Grabcut algorithm.We compared the deep learning performance results of original data,data using only K-means clustering,and data using both K-means clustering and the Grabcut algorithm.All data used in this paper were collected at Soonchunhyang University Cheonan Hospital in Korea and the experimental test proceeded with IRB approval.The training was conducted using Resnet 50,VGG,and Inception resnet V2 models,and Resnet 50 had the best accuracy in validation and testing.Through the preprocessing process proposed in this paper,the accuracy of deep learning models was significantly improved by at least 10%and up to 40%.展开更多
Nowadays,the COVID-19 virus disease is spreading rampantly.There are some testing tools and kits available for diagnosing the virus,but it is in a lim-ited count.To diagnose the presence of disease from radiological i...Nowadays,the COVID-19 virus disease is spreading rampantly.There are some testing tools and kits available for diagnosing the virus,but it is in a lim-ited count.To diagnose the presence of disease from radiological images,auto-mated COVID-19 diagnosis techniques are needed.The enhancement of AI(Artificial Intelligence)has been focused in previous research,which uses X-ray images for detecting COVID-19.The most common symptoms of COVID-19 are fever,dry cough and sore throat.These symptoms may lead to an increase in the rigorous type of pneumonia with a severe barrier.Since medical imaging is not suggested recently in Canada for critical COVID-19 diagnosis,computer-aided systems are implemented for the early identification of COVID-19,which aids in noticing the disease progression and thus decreases the death rate.Here,a deep learning-based automated method for the extraction of features and classi-fication is enhanced for the detection of COVID-19 from the images of computer tomography(CT).The suggested method functions on the basis of three main pro-cesses:data preprocessing,the extraction of features and classification.This approach integrates the union of deep features with the help of Inception 14 and VGG-16 models.At last,a classifier of Multi-scale Improved ResNet(MSI-ResNet)is developed to detect and classify the CT images into unique labels of class.With the support of available open-source COVID-CT datasets that consists of 760 CT pictures,the investigational validation of the suggested method is estimated.The experimental results reveal that the proposed approach offers greater performance with high specificity,accuracy and sensitivity.展开更多
Objective:To analyze the characteristics,dynamic changes,and outcomes of the first imaging manifestations of 3 patients with severe COVID-19 in our hospital.Methods:Computed tomography(CT)findings of 3 patients with s...Objective:To analyze the characteristics,dynamic changes,and outcomes of the first imaging manifestations of 3 patients with severe COVID-19 in our hospital.Methods:Computed tomography(CT)findings of 3 patients with severe COVID-19 who tested positive by the nucleic acid test in our hospital were selected,mainly focusing on the morphology,distribution characteristics,and dynamic changes of the first CT findings.Results:3 patients with severe pneumonia were older,with one aged 80.The first chest CT examination for all 3 patients differed.Imaging showed a leafy distribution of consolidation,primarily affecting the lower lobes of both lungs and extending subpleurally.A grid-like pattern was observed,along with changes in the consolidation and air bronchogram.These changes had slower absorption,especially in patients with underlying diseases.Conclusion:CT manifestations of severe COVID-19 have specific characteristics and the analysis of their characteristics and dynamic changes provide valuable insights for clinical treatment.展开更多
Objective:To analyze the value of multi-slice spiral computed tomography(CT)and magnetic resonance imaging(MRI)in the diagnosis of carpal joint injury.Methods:A total of 130 patients with suspected wrist injuries admi...Objective:To analyze the value of multi-slice spiral computed tomography(CT)and magnetic resonance imaging(MRI)in the diagnosis of carpal joint injury.Methods:A total of 130 patients with suspected wrist injuries admitted to the Department of Orthopedics of our hospital from January 2023 to January 2024 were selected and randomly divided into a single group(n=65)and a joint group(n=65).The single group was diagnosed using multi-slice spiral CT,and the joint group was diagnosed using multi-slice spiral CT and magnetic resonance imaging,with pathological diagnosis as the gold standard.The diagnostic results of both groups were compared to the gold standard,and the diagnostic energy efficiency of both groups was compared.Results:The diagnostic results of the single group compared with the gold standard were significant(P<0.05).The diagnostic results of the joint group compared with the gold standard were not significant(P>0.05).The sensitivity and accuracy of diagnosis in the joint group were significantly higher than that in the single group(P<0.05).The specificity of diagnosis in the joint group was higher as compared to that in the single group(P>0.05).Conclusion:The combination of multi-slice spiral CT and MRI was highly accurate in diagnosing wrist injuries,and the misdiagnosis rate and leakage rate were relatively low.Hence,this diagnostic program is recommended to be popularized.展开更多
Proton computed tomography(CT)has a distinct practical significance in clinical applications.It eliminates 3–5%errors caused by the transformation of Hounsfield unit(HU)to relative stopping power(RSP)values when usin...Proton computed tomography(CT)has a distinct practical significance in clinical applications.It eliminates 3–5%errors caused by the transformation of Hounsfield unit(HU)to relative stopping power(RSP)values when using X-ray CT for positioning and treatment planning systems(TPSs).Following the development of FLASH proton therapy,there are increased requirements for accurate and rapid positioning in TPSs.Thus,a new rapid proton CT imaging mode is proposed based on sparsely sampled projections.The proton beam was boosted to 350 MeV by a compact proton linear accelerator(LINAC).In this study,the comparisons of the proton scattering with the energy of 350 MeV and 230 MeV are conducted based on GEANT4 simulations.As the sparsely sampled information associated with beam acquisitions at 12 angles is not enough for reconstruction,X-ray CT is used as a prior image.The RSP map generated by converting the X-ray CT was constructed based on Monte Carlo simulations.Considering the estimation of the most likely path(MLP),the prior image-constrained compressed sensing(PICCS)algorithm is used to reconstruct images from two different phantoms using sparse proton projections of 350 MeV parallel proton beam.The results show that it is feasible to realize the proton image reconstruction with the rapid proton CT imaging proposed in this paper.It can produce RSP maps with much higher accuracy for TPSs and fast positioning to achieve ultra-fast imaging for real-time image-guided radiotherapy(IGRT)in clinical proton therapy applications.展开更多
Liver cancer is one of the major diseases with increased mortality in recent years,across the globe.Manual detection of liver cancer is a tedious and laborious task due to which Computer Aided Diagnosis(CAD)models hav...Liver cancer is one of the major diseases with increased mortality in recent years,across the globe.Manual detection of liver cancer is a tedious and laborious task due to which Computer Aided Diagnosis(CAD)models have been developed to detect the presence of liver cancer accurately and classify its stages.Besides,liver cancer segmentation outcome,using medical images,is employed in the assessment of tumor volume,further treatment plans,and response moni-toring.Hence,there is a need exists to develop automated tools for liver cancer detection in a precise manner.With this motivation,the current study introduces an Intelligent Artificial Intelligence with Equilibrium Optimizer based Liver cancer Classification(IAIEO-LCC)model.The proposed IAIEO-LCC technique initially performs Median Filtering(MF)-based pre-processing and data augmentation process.Besides,Kapur’s entropy-based segmentation technique is used to identify the affected regions in liver.Moreover,VGG-19 based feature extractor and Equilibrium Optimizer(EO)-based hyperparameter tuning processes are also involved to derive the feature vectors.At last,Stacked Gated Recurrent Unit(SGRU)classifier is exploited to detect and classify the liver cancer effectively.In order to demonstrate the superiority of the proposed IAIEO-LCC technique in terms of performance,a wide range of simulations was conducted and the results were inspected under different measures.The comparison study results infer that the proposed IAIEO-LCC technique achieved an improved accuracy of 98.52%.展开更多
Computed Tomography(CT)images have been extensively employed in disease diagnosis and treatment,causing a huge concern over the dose of radiation to which patients are exposed.Increasing the radiation dose to get a be...Computed Tomography(CT)images have been extensively employed in disease diagnosis and treatment,causing a huge concern over the dose of radiation to which patients are exposed.Increasing the radiation dose to get a better image may lead to the development of genetic disorders and cancer in the patients;on the other hand,decreasing it by using a Low-Dose CT(LDCT)image may cause more noise and increased artifacts,which can compromise the diagnosis.So,image reconstruction from LDCT image data is necessary to improve radiologists’judgment and confidence.This study proposed three novel models for denoising LDCT images based on Wasserstein Generative Adversarial Network(WGAN).They were incorporated with different loss functions,including Visual Geometry Group(VGG),Structural Similarity Loss(SSIM),and Structurally Sensitive Loss(SSL),to reduce noise and preserve important information on LDCT images and investigate the effect of different types of loss functions.Furthermore,experiments have been conducted on the Graphical Processing Unit(GPU)and Central Processing Unit(CPU)to compare the performance of the proposed models.The results demonstrated that images from the proposed WGAN-SSIM,WGAN-VGG-SSIM,and WGAN-VGG-SSL were denoised better than those from state-of-the-art models(WGAN,WGAN-VGG,and SMGAN)and converged to a stable equilibrium compared with WGAN and WGAN-VGG.The proposed models are effective in reducing noise,suppressing artifacts,and maintaining informative structure and texture details,especially WGAN-VGG-SSL which achieved a high peak-signalto-noise ratio(PNSR)on both GPU(26.1336)and CPU(25.8270).The average accuracy of WGAN-VGG-SSL outperformed that of the state-ofthe-art methods by 1 percent.Experiments prove that theWGAN-VGG-SSL is more stable than the other models on both GPU and CPU.展开更多
In civil aviation security screening, laptops, with their intricate structural composition, provide the potential for criminals to conceal dangerous items. Presently, the security process necessitates passengers to in...In civil aviation security screening, laptops, with their intricate structural composition, provide the potential for criminals to conceal dangerous items. Presently, the security process necessitates passengers to individually present their laptops for inspection. The paper introduced a method for laptop removal. By combining projection algorithms with the YOLOv7-Seg model, a laptop’s three views were generated through projection, and instance segmentation of these views was achieved using YOLOv7-Seg. The resulting 2D masks from instance segmentation at different angles were employed to reconstruct a 3D mask through angle restoration. Ultimately, the intersection of this 3D mask with the original 3D data enabled the successful extraction of the laptop’s 3D information. Experimental results demonstrated that the fusion of projection and instance segmentation facilitated the automatic removal of laptops from CT data. Moreover, higher instance segmentation model accuracy leads to more precise removal outcomes. By implementing the laptop removal functionality, the civil aviation security screening process becomes more efficient and convenient. Passengers will no longer be required to individually handle their laptops, effectively enhancing the efficiency and accuracy of security screening.展开更多
基金the Deanship for Research Innovation,Ministry of Education in Saudi Arabia,for funding this research work through project number IFKSUDR-H122.
文摘In the current landscape of the COVID-19 pandemic,the utilization of deep learning in medical imaging,especially in chest computed tomography(CT)scan analysis for virus detection,has become increasingly significant.Despite its potential,deep learning’s“black box”nature has been a major impediment to its broader acceptance in clinical environments,where transparency in decision-making is imperative.To bridge this gap,our research integrates Explainable AI(XAI)techniques,specifically the Local Interpretable Model-Agnostic Explanations(LIME)method,with advanced deep learning models.This integration forms a sophisticated and transparent framework for COVID-19 identification,enhancing the capability of standard Convolutional Neural Network(CNN)models through transfer learning and data augmentation.Our approach leverages the refined DenseNet201 architecture for superior feature extraction and employs data augmentation strategies to foster robust model generalization.The pivotal element of our methodology is the use of LIME,which demystifies the AI decision-making process,providing clinicians with clear,interpretable insights into the AI’s reasoning.This unique combination of an optimized Deep Neural Network(DNN)with LIME not only elevates the precision in detecting COVID-19 cases but also equips healthcare professionals with a deeper understanding of the diagnostic process.Our method,validated on the SARS-COV-2 CT-Scan dataset,demonstrates exceptional diagnostic accuracy,with performance metrics that reinforce its potential for seamless integration into modern healthcare systems.This innovative approach marks a significant advancement in creating explainable and trustworthy AI tools for medical decisionmaking in the ongoing battle against COVID-19.
基金This research was supported under the framework of an international cooperation program managed by the National Research Foundation of Korea(NRF-2019K1A3A1A20093097)supported by the National Key Research and Development Program of China(2019YFE0107800)was supported by the Soonchunhyang University Research Fund。
文摘Specific medical data has limitations in that there are not many numbers and it is not standardized.to solve these limitations,it is necessary to study how to efficiently process these limited amounts of data.In this paper,deep learning methods for automatically determining cardiovascular diseases are described,and an effective preprocessing method for CT images that can be applied to improve the performance of deep learning was conducted.The cardiac CT images include several parts of the body such as the heart,lungs,spine,and ribs.The preprocessing step proposed in this paper divided CT image data into regions of interest and other regions using K-means clustering and the Grabcut algorithm.We compared the deep learning performance results of original data,data using only K-means clustering,and data using both K-means clustering and the Grabcut algorithm.All data used in this paper were collected at Soonchunhyang University Cheonan Hospital in Korea and the experimental test proceeded with IRB approval.The training was conducted using Resnet 50,VGG,and Inception resnet V2 models,and Resnet 50 had the best accuracy in validation and testing.Through the preprocessing process proposed in this paper,the accuracy of deep learning models was significantly improved by at least 10%and up to 40%.
基金Supporting this research through Taif University Researchers Supporting Project number(TURSP-2020/231),Taif University,Taif,Saudi Arabia.
文摘Nowadays,the COVID-19 virus disease is spreading rampantly.There are some testing tools and kits available for diagnosing the virus,but it is in a lim-ited count.To diagnose the presence of disease from radiological images,auto-mated COVID-19 diagnosis techniques are needed.The enhancement of AI(Artificial Intelligence)has been focused in previous research,which uses X-ray images for detecting COVID-19.The most common symptoms of COVID-19 are fever,dry cough and sore throat.These symptoms may lead to an increase in the rigorous type of pneumonia with a severe barrier.Since medical imaging is not suggested recently in Canada for critical COVID-19 diagnosis,computer-aided systems are implemented for the early identification of COVID-19,which aids in noticing the disease progression and thus decreases the death rate.Here,a deep learning-based automated method for the extraction of features and classi-fication is enhanced for the detection of COVID-19 from the images of computer tomography(CT).The suggested method functions on the basis of three main pro-cesses:data preprocessing,the extraction of features and classification.This approach integrates the union of deep features with the help of Inception 14 and VGG-16 models.At last,a classifier of Multi-scale Improved ResNet(MSI-ResNet)is developed to detect and classify the CT images into unique labels of class.With the support of available open-source COVID-CT datasets that consists of 760 CT pictures,the investigational validation of the suggested method is estimated.The experimental results reveal that the proposed approach offers greater performance with high specificity,accuracy and sensitivity.
基金Qinghai Provincial Health Commission Medical and Health Science and Technology Project Guiding Topics“Analysis of Dynamic Changes in Chest Imaging of New Coronavirus Pneumonia in Qinghai Province”(2022-wjzdx-63)。
文摘Objective:To analyze the characteristics,dynamic changes,and outcomes of the first imaging manifestations of 3 patients with severe COVID-19 in our hospital.Methods:Computed tomography(CT)findings of 3 patients with severe COVID-19 who tested positive by the nucleic acid test in our hospital were selected,mainly focusing on the morphology,distribution characteristics,and dynamic changes of the first CT findings.Results:3 patients with severe pneumonia were older,with one aged 80.The first chest CT examination for all 3 patients differed.Imaging showed a leafy distribution of consolidation,primarily affecting the lower lobes of both lungs and extending subpleurally.A grid-like pattern was observed,along with changes in the consolidation and air bronchogram.These changes had slower absorption,especially in patients with underlying diseases.Conclusion:CT manifestations of severe COVID-19 have specific characteristics and the analysis of their characteristics and dynamic changes provide valuable insights for clinical treatment.
文摘Objective:To analyze the value of multi-slice spiral computed tomography(CT)and magnetic resonance imaging(MRI)in the diagnosis of carpal joint injury.Methods:A total of 130 patients with suspected wrist injuries admitted to the Department of Orthopedics of our hospital from January 2023 to January 2024 were selected and randomly divided into a single group(n=65)and a joint group(n=65).The single group was diagnosed using multi-slice spiral CT,and the joint group was diagnosed using multi-slice spiral CT and magnetic resonance imaging,with pathological diagnosis as the gold standard.The diagnostic results of both groups were compared to the gold standard,and the diagnostic energy efficiency of both groups was compared.Results:The diagnostic results of the single group compared with the gold standard were significant(P<0.05).The diagnostic results of the joint group compared with the gold standard were not significant(P>0.05).The sensitivity and accuracy of diagnosis in the joint group were significantly higher than that in the single group(P<0.05).The specificity of diagnosis in the joint group was higher as compared to that in the single group(P>0.05).Conclusion:The combination of multi-slice spiral CT and MRI was highly accurate in diagnosing wrist injuries,and the misdiagnosis rate and leakage rate were relatively low.Hence,this diagnostic program is recommended to be popularized.
基金supported by the Research collaboration on Thailand’s new synchrotron light source facility(SPS-II)(No.ANSO-CR-KP-2020-16).
文摘Proton computed tomography(CT)has a distinct practical significance in clinical applications.It eliminates 3–5%errors caused by the transformation of Hounsfield unit(HU)to relative stopping power(RSP)values when using X-ray CT for positioning and treatment planning systems(TPSs).Following the development of FLASH proton therapy,there are increased requirements for accurate and rapid positioning in TPSs.Thus,a new rapid proton CT imaging mode is proposed based on sparsely sampled projections.The proton beam was boosted to 350 MeV by a compact proton linear accelerator(LINAC).In this study,the comparisons of the proton scattering with the energy of 350 MeV and 230 MeV are conducted based on GEANT4 simulations.As the sparsely sampled information associated with beam acquisitions at 12 angles is not enough for reconstruction,X-ray CT is used as a prior image.The RSP map generated by converting the X-ray CT was constructed based on Monte Carlo simulations.Considering the estimation of the most likely path(MLP),the prior image-constrained compressed sensing(PICCS)algorithm is used to reconstruct images from two different phantoms using sparse proton projections of 350 MeV parallel proton beam.The results show that it is feasible to realize the proton image reconstruction with the rapid proton CT imaging proposed in this paper.It can produce RSP maps with much higher accuracy for TPSs and fast positioning to achieve ultra-fast imaging for real-time image-guided radiotherapy(IGRT)in clinical proton therapy applications.
基金The Deanship of Scientific Research(DSR)at King Abdulaziz University,Jeddah,Saudi Arabia has funded this project,under grant no.(FP-206-43).
文摘Liver cancer is one of the major diseases with increased mortality in recent years,across the globe.Manual detection of liver cancer is a tedious and laborious task due to which Computer Aided Diagnosis(CAD)models have been developed to detect the presence of liver cancer accurately and classify its stages.Besides,liver cancer segmentation outcome,using medical images,is employed in the assessment of tumor volume,further treatment plans,and response moni-toring.Hence,there is a need exists to develop automated tools for liver cancer detection in a precise manner.With this motivation,the current study introduces an Intelligent Artificial Intelligence with Equilibrium Optimizer based Liver cancer Classification(IAIEO-LCC)model.The proposed IAIEO-LCC technique initially performs Median Filtering(MF)-based pre-processing and data augmentation process.Besides,Kapur’s entropy-based segmentation technique is used to identify the affected regions in liver.Moreover,VGG-19 based feature extractor and Equilibrium Optimizer(EO)-based hyperparameter tuning processes are also involved to derive the feature vectors.At last,Stacked Gated Recurrent Unit(SGRU)classifier is exploited to detect and classify the liver cancer effectively.In order to demonstrate the superiority of the proposed IAIEO-LCC technique in terms of performance,a wide range of simulations was conducted and the results were inspected under different measures.The comparison study results infer that the proposed IAIEO-LCC technique achieved an improved accuracy of 98.52%.
文摘Computed Tomography(CT)images have been extensively employed in disease diagnosis and treatment,causing a huge concern over the dose of radiation to which patients are exposed.Increasing the radiation dose to get a better image may lead to the development of genetic disorders and cancer in the patients;on the other hand,decreasing it by using a Low-Dose CT(LDCT)image may cause more noise and increased artifacts,which can compromise the diagnosis.So,image reconstruction from LDCT image data is necessary to improve radiologists’judgment and confidence.This study proposed three novel models for denoising LDCT images based on Wasserstein Generative Adversarial Network(WGAN).They were incorporated with different loss functions,including Visual Geometry Group(VGG),Structural Similarity Loss(SSIM),and Structurally Sensitive Loss(SSL),to reduce noise and preserve important information on LDCT images and investigate the effect of different types of loss functions.Furthermore,experiments have been conducted on the Graphical Processing Unit(GPU)and Central Processing Unit(CPU)to compare the performance of the proposed models.The results demonstrated that images from the proposed WGAN-SSIM,WGAN-VGG-SSIM,and WGAN-VGG-SSL were denoised better than those from state-of-the-art models(WGAN,WGAN-VGG,and SMGAN)and converged to a stable equilibrium compared with WGAN and WGAN-VGG.The proposed models are effective in reducing noise,suppressing artifacts,and maintaining informative structure and texture details,especially WGAN-VGG-SSL which achieved a high peak-signalto-noise ratio(PNSR)on both GPU(26.1336)and CPU(25.8270).The average accuracy of WGAN-VGG-SSL outperformed that of the state-ofthe-art methods by 1 percent.Experiments prove that theWGAN-VGG-SSL is more stable than the other models on both GPU and CPU.
文摘In civil aviation security screening, laptops, with their intricate structural composition, provide the potential for criminals to conceal dangerous items. Presently, the security process necessitates passengers to individually present their laptops for inspection. The paper introduced a method for laptop removal. By combining projection algorithms with the YOLOv7-Seg model, a laptop’s three views were generated through projection, and instance segmentation of these views was achieved using YOLOv7-Seg. The resulting 2D masks from instance segmentation at different angles were employed to reconstruct a 3D mask through angle restoration. Ultimately, the intersection of this 3D mask with the original 3D data enabled the successful extraction of the laptop’s 3D information. Experimental results demonstrated that the fusion of projection and instance segmentation facilitated the automatic removal of laptops from CT data. Moreover, higher instance segmentation model accuracy leads to more precise removal outcomes. By implementing the laptop removal functionality, the civil aviation security screening process becomes more efficient and convenient. Passengers will no longer be required to individually handle their laptops, effectively enhancing the efficiency and accuracy of security screening.
