Purpose:To investigate the association between high anisometropia and the area of choroidal neovascularization (CNV) induced by krypton laser in guinea pigs and better understand the pathogenesis and prevention of myo...Purpose:To investigate the association between high anisometropia and the area of choroidal neovascularization (CNV) induced by krypton laser in guinea pigs and better understand the pathogenesis and prevention of myopic CNV. Methods:.Nine 3-week old male guinea pigs with anisometropia > 6.00D were randomly assigned to three groups according to examination date after laser photocoagulation (7d, 14d and 28d). All animals underwent refraction. The eye with higher myopia was used as the experimental eye, and the other as the control eye..All eyes received repeated multi-wavelength krypton laser photocoagulation treatments (wavelength: 532 nm; laser power: 400 mW; spot diameter: 50 μm; exposure time: 0.1s). Fundus photography and indocyanine green angiography (ICGA) were performed. Afterwards, the animals were sacrificed immediately,.and the eyes were enucleated and processed for histopathologic examination and flat mounts. Results: CNV appeared at 7d after laser treatment. The area of CNV peaked at 14d, and decrease in area and the presence of scarring was noted at 28 d..CNV was present in 66.7% of eyes by ICGA at 14 d..CNV could be observed under light microscopy at all three time points..At 14 d,.flat mount showed the neovascular plexus around the lesion. Semi-quantitative analysis revealed that the area of CNV in treated eyes was greater than that of control eyes. Conclusion:.Since the mechanism of CNV in this study resembles that of CNV in pathological myopia, this model can be used to investigate the etiology, pathogenesis and treatment of CNV in pathological myopia.展开更多
High-resolution absorption spectra of atomic krypton in the range of 11870-12700 cm-1 were recorded by employing concentration modulation absorption spectroscopy technique with a tunable single-mode cw Ti:Sapphire las...High-resolution absorption spectra of atomic krypton in the range of 11870-12700 cm-1 were recorded by employing concentration modulation absorption spectroscopy technique with a tunable single-mode cw Ti:Sapphire laser. The krypton atoms were excited to the absorbing energy states by discharge-burning in a mixture of helium and krypton. A total of 120 lines of neutral krypton were observed, among them 33 lines had already been classified in previous studies, 45 lines were newly classified with the known energy levels, and 42 lines cannot be classified. These unclassified lines indicate that up to now unknown energy levels of Kr must exist. Further, an analysis of the unclassified lines to get possible new energy levels with a classification program is reported.展开更多
The valence-shell excitations of krypton atom have been investigated by fast electron impact with an angle-resolved electron-energy-loss spectrometer. The generalized oscillator strengths for some higher mixed valence...The valence-shell excitations of krypton atom have been investigated by fast electron impact with an angle-resolved electron-energy-loss spectrometer. The generalized oscillator strengths for some higher mixed valence-shell excitations in 4d, 4f, 5p, 5d, 6s, 6p, 7s ←4p of krypton atom have been determined. Their profiles are discussed, and the generalized oscillator strengths for the electric monopole and quadrupole excitations in 5p ← 4p are compared with the calculations of Amusia et al. (Phys. Rev. A 67 022703 (2003)). The differences between the experimental results and theoretical calculations show that more studies are needed.展开更多
Electron cyclotron resonance radio frequency (ECR-rf) hybrid krypton-diluted oxygen plasmas were used to pattern the surfaces of diamond films with the assistance of a physical mask, while optical emission spectrosc...Electron cyclotron resonance radio frequency (ECR-rf) hybrid krypton-diluted oxygen plasmas were used to pattern the surfaces of diamond films with the assistance of a physical mask, while optical emission spectroscopy was employed to characterize the plasma. It was found that with krypton dilution the etching rate decreased, and also the aspect ratios of nanotips formed in micro-holes were significantly modified. The oxygen atomic densities were estimated by oxygen atom optical emission and argon actinometry. Under a microwave power of 300 W and rf bias of-300 V, the absolute density of ground-state oxygen atoms decreased from 1.3×10^12 cm^-3 to 1.4×10^11 cm^-3 as the krypton dilution ratio increased to 80%, accompanied by the decrease in the plasma excitation temperature. It is concluded that oxygen atoms play a dominant role in diamond etching. The relative variations in the horizontal and vertical etching rates induced by the addition of krypton are attributed to the observations of thicker nanotips at a high krypton dilution ratio.展开更多
Effects of argon, krypton and their mixed pressure treatments on the quality of white mushrooms were studied during 9 days of storage at 4℃. Among all treatments in this study, the minimum respiration rate, polypheno...Effects of argon, krypton and their mixed pressure treatments on the quality of white mushrooms were studied during 9 days of storage at 4℃. Among all treatments in this study, the minimum respiration rate, polyphenoloxidase activity, retained color change, antioxidants and delayed pseudomonas growth were observed with pressure argon (5 MPa) followed by mixing argon and krypton (2.5 MPa each) treatments. Respiration rates after 9 days of storage were 5.35%, 6.20%, 7.50%, 7.60%, 7.91% and 8.95% for HA5, HAK, HA2, HK5, HK2 and control, respectively. DPPH inhibition percentages of free radical for HA5, HAK, HK5, HA2, HK2 and control mushrooms were 28.03%, 25.24%, 24.96%, 21.87%, 20.56% and 19.06%, respectively, after 9 days of storage. The pressurized argon treatment was the most effective compared to pressurized krypton. Thus, application of pressurized argon and krypton treatments could extend the storage life of white mushrooms to 9 days at 4℃.展开更多
The inert gas radioactive isotope ^(85)Kr(with a half-life of 10.74 years), due to its stable physical and chemical properties, is an ideal tracer for shallow groundwater dating. In such a dating application, first th...The inert gas radioactive isotope ^(85)Kr(with a half-life of 10.74 years), due to its stable physical and chemical properties, is an ideal tracer for shallow groundwater dating. In such a dating application, first the dissolved gas is extracted from groundwater in the field, then krypton is separated from the gas sample, and finally the isotopic abundance ^(85)Kr/Kr will be determined by an ATTA instrument. According to the atmospheric input curve of ^(85)Kr, the ^(85)Kr age of groundwater is determined. We conducted ^(85)Kr analysis in three wells in Zhengding County on the plains in front of the Taihang Mountains, and made a comparison with tritium(~3H) method.展开更多
The generation of hollow atoms will reduce the probability of light absorption and provide a high-quality diffraction image in the experiment. In this paper, we calculated the ionization rate of the Kr atom under x-ra...The generation of hollow atoms will reduce the probability of light absorption and provide a high-quality diffraction image in the experiment. In this paper, we calculated the ionization rate of the Kr atom under x-ray free-electron laser(XFEL) using Hartree–Fock–Slater model and simulated the ionization model of Kr atom using Monte–Carlo method to determine the response of the hollow atom of Kr atom to the XFEL photon energy. Calculating the correlation between the total photoionization cross-section of the ground state of Kr atom and the photon energy, we determined three particular photon energies of 1.75 ke V, 1.90 ke V, and 14.30 ke V. The dynamics simulation under the experimental condition's17.50 ke V photon energy was achieved by implementing the Monte–Carlo method and calibrating the photon flux modeling parameters. Consequently, our calculated data are more consistent with experimental phenomena than previous theoretical studies. The saturable absorption of Kr at 1.75 ke V, 1.90 ke V, 14.30 ke V, and 17.50 ke V energies was further investigated by using the optimized photon flux model theory. We compared the statistics on main ionization paths under those four specific photon energies and calculated the population changes of various Kr hollow atoms with different configurations.The results demonstrate that the population of hollow atoms produced at the critical ionization photon energy is high. Furthermore, the change of population with respect to position is smooth, which shows a significant difference between the generation mode of ions with low and high photon energies. The result is important for the study of medium-and high-Z element hollow atoms, which has substantial implications for the study of hollow atoms with medium and high charge states, as well as for the scaling of photon energy of free electron lasers.展开更多
文摘Purpose:To investigate the association between high anisometropia and the area of choroidal neovascularization (CNV) induced by krypton laser in guinea pigs and better understand the pathogenesis and prevention of myopic CNV. Methods:.Nine 3-week old male guinea pigs with anisometropia > 6.00D were randomly assigned to three groups according to examination date after laser photocoagulation (7d, 14d and 28d). All animals underwent refraction. The eye with higher myopia was used as the experimental eye, and the other as the control eye..All eyes received repeated multi-wavelength krypton laser photocoagulation treatments (wavelength: 532 nm; laser power: 400 mW; spot diameter: 50 μm; exposure time: 0.1s). Fundus photography and indocyanine green angiography (ICGA) were performed. Afterwards, the animals were sacrificed immediately,.and the eyes were enucleated and processed for histopathologic examination and flat mounts. Results: CNV appeared at 7d after laser treatment. The area of CNV peaked at 14d, and decrease in area and the presence of scarring was noted at 28 d..CNV was present in 66.7% of eyes by ICGA at 14 d..CNV could be observed under light microscopy at all three time points..At 14 d,.flat mount showed the neovascular plexus around the lesion. Semi-quantitative analysis revealed that the area of CNV in treated eyes was greater than that of control eyes. Conclusion:.Since the mechanism of CNV in this study resembles that of CNV in pathological myopia, this model can be used to investigate the etiology, pathogenesis and treatment of CNV in pathological myopia.
基金supported by the National Natural Science Foundation of China (No.11674096)
文摘High-resolution absorption spectra of atomic krypton in the range of 11870-12700 cm-1 were recorded by employing concentration modulation absorption spectroscopy technique with a tunable single-mode cw Ti:Sapphire laser. The krypton atoms were excited to the absorbing energy states by discharge-burning in a mixture of helium and krypton. A total of 120 lines of neutral krypton were observed, among them 33 lines had already been classified in previous studies, 45 lines were newly classified with the known energy levels, and 42 lines cannot be classified. These unclassified lines indicate that up to now unknown energy levels of Kr must exist. Further, an analysis of the unclassified lines to get possible new energy levels with a classification program is reported.
基金Project supported by the National Natural Science Foundation of China (Grant No 10474089).
文摘The valence-shell excitations of krypton atom have been investigated by fast electron impact with an angle-resolved electron-energy-loss spectrometer. The generalized oscillator strengths for some higher mixed valence-shell excitations in 4d, 4f, 5p, 5d, 6s, 6p, 7s ←4p of krypton atom have been determined. Their profiles are discussed, and the generalized oscillator strengths for the electric monopole and quadrupole excitations in 5p ← 4p are compared with the calculations of Amusia et al. (Phys. Rev. A 67 022703 (2003)). The differences between the experimental results and theoretical calculations show that more studies are needed.
基金supported by National Natural Science Foundation of China (No. 10635010)National Basic Research Program of China (No. 2008CB717800)
文摘Electron cyclotron resonance radio frequency (ECR-rf) hybrid krypton-diluted oxygen plasmas were used to pattern the surfaces of diamond films with the assistance of a physical mask, while optical emission spectroscopy was employed to characterize the plasma. It was found that with krypton dilution the etching rate decreased, and also the aspect ratios of nanotips formed in micro-holes were significantly modified. The oxygen atomic densities were estimated by oxygen atom optical emission and argon actinometry. Under a microwave power of 300 W and rf bias of-300 V, the absolute density of ground-state oxygen atoms decreased from 1.3×10^12 cm^-3 to 1.4×10^11 cm^-3 as the krypton dilution ratio increased to 80%, accompanied by the decrease in the plasma excitation temperature. It is concluded that oxygen atoms play a dominant role in diamond etching. The relative variations in the horizontal and vertical etching rates induced by the addition of krypton are attributed to the observations of thicker nanotips at a high krypton dilution ratio.
文摘Effects of argon, krypton and their mixed pressure treatments on the quality of white mushrooms were studied during 9 days of storage at 4℃. Among all treatments in this study, the minimum respiration rate, polyphenoloxidase activity, retained color change, antioxidants and delayed pseudomonas growth were observed with pressure argon (5 MPa) followed by mixing argon and krypton (2.5 MPa each) treatments. Respiration rates after 9 days of storage were 5.35%, 6.20%, 7.50%, 7.60%, 7.91% and 8.95% for HA5, HAK, HA2, HK5, HK2 and control, respectively. DPPH inhibition percentages of free radical for HA5, HAK, HK5, HA2, HK2 and control mushrooms were 28.03%, 25.24%, 24.96%, 21.87%, 20.56% and 19.06%, respectively, after 9 days of storage. The pressurized argon treatment was the most effective compared to pressurized krypton. Thus, application of pressurized argon and krypton treatments could extend the storage life of white mushrooms to 9 days at 4℃.
基金supported by the National Natural Science Foundation of China (41102151)Public Science and Technology Research Funds Projects of Ministry of Land and Resources(201511046)
文摘The inert gas radioactive isotope ^(85)Kr(with a half-life of 10.74 years), due to its stable physical and chemical properties, is an ideal tracer for shallow groundwater dating. In such a dating application, first the dissolved gas is extracted from groundwater in the field, then krypton is separated from the gas sample, and finally the isotopic abundance ^(85)Kr/Kr will be determined by an ATTA instrument. According to the atmospheric input curve of ^(85)Kr, the ^(85)Kr age of groundwater is determined. We conducted ^(85)Kr analysis in three wells in Zhengding County on the plains in front of the Taihang Mountains, and made a comparison with tritium(~3H) method.
基金the Fundamental Research Funds for the Central Universities (Grant No. 10822041A2038)。
文摘The generation of hollow atoms will reduce the probability of light absorption and provide a high-quality diffraction image in the experiment. In this paper, we calculated the ionization rate of the Kr atom under x-ray free-electron laser(XFEL) using Hartree–Fock–Slater model and simulated the ionization model of Kr atom using Monte–Carlo method to determine the response of the hollow atom of Kr atom to the XFEL photon energy. Calculating the correlation between the total photoionization cross-section of the ground state of Kr atom and the photon energy, we determined three particular photon energies of 1.75 ke V, 1.90 ke V, and 14.30 ke V. The dynamics simulation under the experimental condition's17.50 ke V photon energy was achieved by implementing the Monte–Carlo method and calibrating the photon flux modeling parameters. Consequently, our calculated data are more consistent with experimental phenomena than previous theoretical studies. The saturable absorption of Kr at 1.75 ke V, 1.90 ke V, 14.30 ke V, and 17.50 ke V energies was further investigated by using the optimized photon flux model theory. We compared the statistics on main ionization paths under those four specific photon energies and calculated the population changes of various Kr hollow atoms with different configurations.The results demonstrate that the population of hollow atoms produced at the critical ionization photon energy is high. Furthermore, the change of population with respect to position is smooth, which shows a significant difference between the generation mode of ions with low and high photon energies. The result is important for the study of medium-and high-Z element hollow atoms, which has substantial implications for the study of hollow atoms with medium and high charge states, as well as for the scaling of photon energy of free electron lasers.