The destructiveness of impulse waves generated by landslides(IWL) originates from the wave’s movement and load, wherein the impulse wave’s load is the major cause of sub-aerial building damage and casualties. In thi...The destructiveness of impulse waves generated by landslides(IWL) originates from the wave’s movement and load, wherein the impulse wave’s load is the major cause of sub-aerial building damage and casualties. In this study, an experiment involving 16 groups of physical tests for the wave pressure generated by a landslide was designed, consisting of 4 sets of IWL and 4 opposite bank slope angles. A high-frequency strain system was used to measure the total pressure of the impulse wave in a water tank. The tests showed that the dynamic pressure caused by the IWL can be divided into two types: impact pressure generated by the jetflow and the pulsating pressure caused by the wave. Under the same impulse wave conditions, the maximum run-up becomes smaller as the opposite bank’s slope angle increases, and the jetflow maximum impact pressure experienced by the opposite bank increases, while the maximum pulsating pressure caused by the impulse wave is slightly decreased. Different from previous studies, the spatial maximum pressure distributions of the wave generated by landslide were concluded that the position of the maximum pulsating pressure appears adjacent to the still water surface, and the overall spatial distribution pattern of maximum wave pressure is presented as an inclined 'M' shape.Meanwhile, this study is the first to quantitatively analyzed that impact pressure has a very short action time, is even 7 times of the pulse pressure value, and there is a simple mathematical linear relationship between the two. Currently, some wave-load formulas for wind waves and tides are not applicable to calculating the loads of IWL. Research on the load of IWL will explain the hazard of impulse wave very clearly, and will greatly contribute to hazard prevention, mitigation and risk assessment work associated with IWL.展开更多
A numerical model is proposed for the simulation of impulse waves generated by landslides. The fluid-like landslide is modeled as a generalized non-Newtonian visco-plastic fluid. The conservative level set method is e...A numerical model is proposed for the simulation of impulse waves generated by landslides. The fluid-like landslide is modeled as a generalized non-Newtonian visco-plastic fluid. The conservative level set method is extended to the n-phase flow and applied to capture the interfaces of air, water and landslide. Numerical results show an excellent performance of the current model to capture the whole process of the landslide and the impulse wave generation.展开更多
Landslide-generated impulsive waves(LGWs)in reservoir areas can seriously threaten waterway safety as well as hu-man life and properties around the two side slopes.The risk reduction and mitigation of such a hazard re...Landslide-generated impulsive waves(LGWs)in reservoir areas can seriously threaten waterway safety as well as hu-man life and properties around the two side slopes.The risk reduction and mitigation of such a hazard require the accurate prediction of near-field wave characteristics,such as wave amplitude and run-up.However,near-field LGW involves complicated fluid-solid interactions.Furthermore,the wave characteristics are closely related to various aspects,including the geometry and physical features of the slide,river,and body of water.However,the empirical or analytical methods used for rough estimation cannot derive accurate results,especially for deformable landslides,due to their significant geometry changes during the sliding process.In this study,the near-field waves generated by deformable landslides were simulated by smoothed particle hydrodynamics(SPH)based on multi-phase flow.The deformable landslides were generalized as a kind of viscous flow by adopting the Herschel-Bulkley-Papanastasiou(HBP)-based nonNewtonian rheology model.The HBP model is capable of producing deformable landslide dynamics even though the high-speed sliding process is involved.In this study,an idealized experiment case originating from Lituya LGW and a practical case of Gongjiafang LGW were reproduced for verification and demonstration.The simulation results of both cases show satisfactory consistency with the experiment/investigation data in terms of landslide movement and near-field impulsive wave characteristics,thus indicating the applicability and accuracy of the proposed method.Finally,the effects of the HBP model’s rheological parameters on the landslide dynamics and near-field wave characteristics are discussed,providing a parameter calibration method along with sug-gestions for further applications.展开更多
BACKGROUND Several studies have demonstrated the feasibility and effectiveness of using ultrasound elastography to assess liver tissue stiffness.Virtual touch imaging quantification(VTIQ)based on acoustic radiation fo...BACKGROUND Several studies have demonstrated the feasibility and effectiveness of using ultrasound elastography to assess liver tissue stiffness.Virtual touch imaging quantification(VTIQ)based on acoustic radiation force impulse imaging has been developed as a latest and noninvasive method for assessing liver stiffness in children.AIM To determine the standard value in healthy children,and to identify possible factors that might influence the VTIQ measurement.METHODS With the ethical approval,202 children between 1 month and 15 years old were included in this study.None of them had any liver or systematic diseases.All children had a normal ultrasound scan and normal body mass index(BMI)range.The subjects were divided into four age and BMI groups.The effects of gender,age,liver lobe,measurement depth,and BMI on liver elasticity were investigated.RESULTS A significant correlation was found between age and shear wave velocity(SWV)value.At measurement depths of 1.5 cm and 2.0 cm in the left lobe,there were significant differences among the age groups.SWV values were significantly negatively correlated with the measurement depth.Gender,liver lobe,and BMI showed no significant effect on the SWV values.Age and BMI may influence the quality of the elastogram.CONCLUSION VTIQ is a noninvasive technique that is feasible to measure liver stiffness in children.The afore-mentioned velocity value obtained utilizing VTIQ method could be used as reference value for normal liver stiffness in children.展开更多
Impulse turbine, working as a typical self-rectifying turbine, is recently utilized for the oscillating water column(OWC) wave energy converters, which can rotate in the same direction under the bi-directional air f...Impulse turbine, working as a typical self-rectifying turbine, is recently utilized for the oscillating water column(OWC) wave energy converters, which can rotate in the same direction under the bi-directional air flows. A numerical model established in Fluent is validated by the corresponding experimental results. The flow fields, pressure distribution and dimensionless evaluating coefficients can be calculated and analyzed. Effects of the rotor solidity varying with the change of blade number are investigated and the suitable solidity value is recommended for different flow coefficients.展开更多
Wells turbine has inherent disadvantages in comparison with conventional turbines: relative low efficiency at high flow coefficient and poor starting characteristics. To solve these problems, the authors propose Wells...Wells turbine has inherent disadvantages in comparison with conventional turbines: relative low efficiency at high flow coefficient and poor starting characteristics. To solve these problems, the authors propose Wells turbine with booster turbine for wave energy conversion, in order to improve the performance in this study. This turbine consists of three parts: a large Wells turbine, a small impulse turbine with fixed guide vanes for oscillating airflow, and a generator. It was conjectured that, by coupling the two axial flow turbines together, pneumatic energy from oscillating airflow is captured by Wells turbine at low flow coefficient and that the impulse turbine gets the energy at high flow coefficient. As the first step of this study on the proposed turbine topology, the performance of turbines under steady flow conditions has been investigated experimentally by model testings. Furthermore, we estimate mean efficiency of the turbine by quasi-steady analysis.展开更多
A twin unidirectional impulse turbine has been proposed in order to enhance the performance of wave energy plant. This turbine system uses two unidirectional impulse turbines and their flow direction is different each...A twin unidirectional impulse turbine has been proposed in order to enhance the performance of wave energy plant. This turbine system uses two unidirectional impulse turbines and their flow direction is different each other. However, the effect of guide vane solidity on the turbine characteristics has not been clarified to date. The performances of a uni- directional impulse turbine under steady flow conditions were investigated experimentally by using a wind tunnel with large piston/cylinder in this study. Then, mean efficiency of the twin impulse turbine in bidirectional airflow has been estimated by a quasi-steady analysis using experimental results in order to investigate the effect of guide vane solidity on the performance.展开更多
A fixed oscillating water column(OWC)-type wave energy converter consists of an air chamber,an air turbine and a generator.The energy conversion processes are the primary conversion in an air chamber and the secondary...A fixed oscillating water column(OWC)-type wave energy converter consists of an air chamber,an air turbine and a generator.The energy conversion processes are the primary conversion in an air chamber and the secondary conversion of the turbine.For the practical use,it is necessary to develop a design method which can consider the incident wave motion,the motion of the internal free surface affected in the structure such as a partly submerged wall,the fluctuation of air pressure in an air chamber,and the rotation of the air turbine.At here,the authors carried out the wave tank tests using the model OWC equipped with the impulse turbine and a generator to obtain the experimental data needed to make this design method.As the result,the efficiencies of the three cases with different speed ratio between generator and turbine,and the effects of the curtain wall depth and the wave length on the energy conversion performance were clarified.展开更多
Objective: The aim of our study was to make the qualitative and quantitative analysis to breast lesions using acoustic radiation force impulses (ARFI), and assess the diagnostic value of ARFI for differentiation be...Objective: The aim of our study was to make the qualitative and quantitative analysis to breast lesions using acoustic radiation force impulses (ARFI), and assess the diagnostic value of ARFI for differentiation between benign and malignant solid breast masses, meanwhile evaluate the influences of ARFI with breast imaging reporting and data system (BI-RADS) of suspicious masses. Methods: Seventy-five women with 86 breast lesions underwent conventional breast ultra- sound examination. Then B-mode BI-RADS features and assessments were recorded and standard breast US supplemented by ARFI elastographic examination were repeated. The data were recorded and analyzed as following: area ratio of breast lesion, the shear-wave velocity, the ratio of the shear-wave velocity between lesions and surrounding normal tissues, and according to the elastographic data reconsidered the BI-RADS category, all the results have been correlated with pathological results and make statistical evaluations of ARFI for differentiation between benign and malignant solid breast masses. Meantime our study has correlated the adjusted BI-RADS category of suspicious breast lesions with the pathological results and made assessment. Results: Thirty-eight patients were malignant breast carcinoma (31 invasive ductal carcinoma, 5 intraductal carcinoma in situ, 2 medullary carcinoma, 2 invasive Iobular carcinoma), 48 patients were benign breast lesions (23 fibroadenoma, 12 benign nodular hyperplasia, 5 phyllodes tumor, 6 adenosis, 2 intraductal papilloma). Underwent conventional breast ultrasound exam, 42 cases were BI-RADS category 3, 23 cases were BI-RADS category 4. When adding elastographic data, 46 cases were BI-RADS category 3 and 20 cases were BI-RADS category 4. Compared with pathological results showed for both the specificity of BIRADS features and the area under ROC curve has risen. Virtual touch tissue imaging (VTI) and virtual touch tissue quantification (VTQ) data showed the area ratio (AR) between elastographic lesions area and B-mode lesions area, SWV (maximal shear-wave velocity of lesions), R-SWV (shear-wave velocity ratio between lesions and surrounding normal tissues) in benign breast lesions were lower than those in malignant lesions which has statistical significance and the cut-off point were 1.1,4.65 m/s, 5.18 respectively. Conclusion: The ARFI elastography can provide the reliable qualitative and quantitative analysis about hardness of breast lesions, supply the new BI-RADS category features to suspicious breast masses and serve as an effective diagnostic tool for differentiation between benign and malignant solid masses.展开更多
By applying the integral transform method and the inverse transformation technique based upon the two types of integration, the present paper has successfully obtained an exact algebraic solution for a two-dimensional...By applying the integral transform method and the inverse transformation technique based upon the two types of integration, the present paper has successfully obtained an exact algebraic solution for a two-dimensional Lamb's problem due to a strip impulse loading for the first time. With the algebraic result, the excitation and propagation processes of stress waves, including the longitudinal wave, the transverse wave, and Rayleigh-wave, are discussed in detail. A few new conclusions have been drawn from currently available integral results or computational results.展开更多
Wave energy is a renewable source with significant amount in relation to the global demand. A good concept of a device applied to extract this type of energy is the onshore oscillating water column wave energy convert...Wave energy is a renewable source with significant amount in relation to the global demand. A good concept of a device applied to extract this type of energy is the onshore oscillating water column wave energy converter(OWC-WEC). This study shows a numerical analysis of the diameter determination of two types of turbines, Wells and Impulse, installed in an onshore OWC device subjected to a hypothetical sea state. Commercial software FLUENT?,which is based on RANS-VoF(Reynolds-Averaged Navier-Stokes equations and Volume of Fluid technique), is employed. A methodology that imposes air pressure on the chamber, considering the air compressibility effect, is used. The mathematical domain consists of a 10 m deep flume with a 10 m long and 10 m wide OWC chamber at its end(geometry is similar to that of the Pico's plant installed in Azores islands, Portugal). On the top of the chamber, a turbine works with air exhalation and inhalation induced by the water free surface which oscillates due to the incident wave. The hypothetical sea state, represented by a group of regular waves with periods from 6 to 12 s and heights from 1.00 to 2.00 m(each wave with an occurrence frequency), is considered to show the potential of the presented methodology. Maximum efficiency(relation between the average output and incident wave powers) of46% was obtained by using a Wells turbine with the diameter of 2.25 m, whereas the efficiency was 44% by an Impulse turbine with the diameter of 1.70 m.展开更多
Neurologists define the transmission of nerve impulses across the membranes of the neural cells as a result of difference in the concentration of ions while they measured an electric potential, called as an action pot...Neurologists define the transmission of nerve impulses across the membranes of the neural cells as a result of difference in the concentration of ions while they measured an electric potential, called as an action potential, which allows the propagation of such nerve impulses as electrical signals. Such measurements should guide them to a logical explanation of the nerve impulses as electric charges driven by the measured action potential. However, such logical conclusion, or explanation, is ignored due to a wrong definition of the flow of electric charges as a flow of electrons that cannot pass through neural networks. According to recent studies, electric charges are properly defined as electromagnetic (EM) waves whose energy is expressed as the product of its propagating electric potential times their entropy flow which is adhered to the flow of such energy. Such definition matches the logical conclusion of the nerve impulses as electric charges, as previously explained, and defines the entropy of the neural network, measured by Ammeters, in Watt or Joule/Volt. The measured entropy represents a neurodiagnostic property of the neural networks that measures its capacity to allow the flow of energy per unit action potential. Theoretical verification of the innovative definition of nerve impulses is presented by following an advanced entropy approach. A proper review of the machine records of the stimulating electric charges, used in the diagnosis of the neural networks, and the stimulated nerve impulses or stimulated responses, represents practical verifications of the innovative definitions of the electric charges and the nerve impulses. Comparing the functioning of the thermoelectric generators and the brain neurons, such neurons are defined as thermoelectric generators of the electric nerve impulses and their propagating, or action, potential.展开更多
Since the CPU of embed system has some limitation in operating speed, a new filter was put forward which implemented mountain template convolution by performing rectangle template convolution two times. It can obtain ...Since the CPU of embed system has some limitation in operating speed, a new filter was put forward which implemented mountain template convolution by performing rectangle template convolution two times. It can obtain time and frequency localization with computational complexity greatly reduced. This algorithm was applied to lightning waveforms (include chopped waveforms) parameter calculation. It simplifies the computation and the results pretreated by this algorithm are in accord with IEC1083-2 completely. It was applied in embed system successfully. Its capability in frequency restraining was researched. The validity of the algorithm was proved in theory when processing lightning waves. The standard sources and the processing results are consistent completely.展开更多
The impulse waves induced by large-reservoir landslides can be characterized by a low Froude number.However,systematic research on predictive models specifically targeting the initial primary wave is lacking.Taking th...The impulse waves induced by large-reservoir landslides can be characterized by a low Froude number.However,systematic research on predictive models specifically targeting the initial primary wave is lacking.Taking the Shuipingzi 1#landslide that occurred in the Baihetan Reservoir area of the Jinsha River in China as an engineering example,this study established a large-scale physical model(with dimensions of 30 m×29 m×3.5 m at a scale of 1:150)and conducted scaled experiments on 3D landslide-induced impulse waves.During the process in which a sliding mass displaced and compressed a body of water to generate waves,the maximum initial wave amplitude was found to be positively correlated with the sliding velocity and the volume of the landslide.With the increase in the water depth,the wave amplitude initially increased and then decreased.The duration of pressure exertion by the sliding mass at its maximum velocity directly correlated with an elevated wave amplitude.Based on the theories of low-amplitude waves and energy conservation,while considering the energy conversion efficiency,a predictive model for the initial wave amplitude was derived.This model could fit and validate the functions of wavelength and wave velocity.The accuracy of the initial wave amplitude was verified using physical experiment data,with a prediction accuracy for the maximum initial wave amplitude reaching 90%.The conversion efficiency(η)directly determined the accuracy of the estimation formula.Under clear conditions for landslide-induced impulse wave generation,estimating the value ofηthrough analogy cases was feasible.This study has derived the landslide-induced impulse waves amplitude prediction formula from the standpoints of wave theory and energy conservation,with greater consideration given to the intrinsic characteristics in the formation process of landslide-induced impulse waves,thereby enhancing the applicability and extensibility of the formula.This can facilitate the development of empirical estimation methods for landslide-induced impulse waves toward universality.展开更多
AIM:To investigate whether a noninvasive measurement of tissue strain has a potential usefulness for management of nonalcoholic steatohepatitis(NASH).METHODS:In total 26 patients,23 NASHs and 3 normal controls were en...AIM:To investigate whether a noninvasive measurement of tissue strain has a potential usefulness for management of nonalcoholic steatohepatitis(NASH).METHODS:In total 26 patients,23 NASHs and 3 normal controls were enrolled in this study.NASH was staged based on Brunt criterion.At a region of interest(ROI),a shear wave was evoked by implementing an acoustic radiation force impulse(ARFI),and the propagation velocity was quantif ied.RESULTS:Shear wave velocity(SWV) could be reproducibly quantified at all ROIs in all subjects except for 4 NASH cases,in which a reliable SWV value was not calculated at several ROIs.An average SWV of 1.34 ± 0.26 m/s in fibrous stage 0-1 was significantly slower than 2.20 ± 0.74 m/s and 2.90 ± 1.01 m/s in stages 3 and 4,respectively,but was not significantly different from 1.79 ± 0.78 m/s in stage 2.When a cutoff value was set at 1.47 m/s,receiver operating characteristic analysis showed significance to dissociate stages 3 and 4 from stage 0-1(P=0.0092) with sensitivity,specificity and area under curve of 100%,75% and 94.2%,respectively.In addition,the correlation between SWV and hyaluronic acid was significant(P<0.0001),while a tendency toward negative correlation was observed with serum albumin(P=0.053).CONCLUSION:The clinical implementation of ARFI provides noninvasive repeated evaluations of liver stiffness at an arbitrary position,which has the potential to shed new light on NASH management.展开更多
BACKGROUND Shear wave speed has been widely applied to quantify a degree of liver fibrosis. However, there is no standardized procedure, which makes it difficult to utilize the speed universally. AIM To provide proced...BACKGROUND Shear wave speed has been widely applied to quantify a degree of liver fibrosis. However, there is no standardized procedure, which makes it difficult to utilize the speed universally. AIM To provide procedural standardization of shear wave speed measurement. METHODS Point shear wave elastography (pSWE) was measured in 781 patients, and twodimensional shear wave elastography (2dSWE) was measured on the same day in 18 cases. Regions-of-interest were placed at 12 sites, and the median and robust coefficient-of-variation (CVR) were calculated. A residual sum-of-square (Σdi2) was computed for bootstrap values of 1000 iterations in 18 cases with each assumption of 1 to 12 measurements. The proportion of the Σdi2 (%Σdi2) was calculated as the ratio of Σdi2 to pSWE after converting it based on the correlation between pSWE and 2dSWE. RESULTS The CVR showed a significantly broader distribution in the left lobe (P < 0.0001),and the smallest CVR in the right anterior segment that covered 95% cases was 40.4%. pSWE was significantly higher in the left lobe than in the right lobe (1.63 ± 0.78 m/s vs 1.61 ± 0.78 m/s, P = 0.0004), and the difference between the lobes became further discrete when the subjects were limited to the cases with a CVR less than 40.4% in any segment (1.76 ± 0.80 m/s vs 1.70 ± 0.82 m/s, P < 0.0001). The highest values of the CVR in every 0.1 m/s interval were plotted in convex upward along pSWE and peaked at 1.93 m/s. pSWE and 2dSWE were significantly correlated (P < 0.0001, r = 0.95). In 216000 resamples from 18 cases, the %Σdi2 of 12 sites was 8.0% and gradually increased as the acquisition sites decreased to reach a significant difference with a %Σdi2 of 7 sites (P = 0.027). CONCLUSION These data suggest that shear wave speed should be measured at 8 or more sites of spreading in both lobes.展开更多
The influence of air pressure on mechanical effect of laser plasma shock wave in a vacuum chamber produced by a Nd:YAG laser has been studied. The laser pulses with pulse width of 10ns and pulse energy of about 320mJ...The influence of air pressure on mechanical effect of laser plasma shock wave in a vacuum chamber produced by a Nd:YAG laser has been studied. The laser pulses with pulse width of 10ns and pulse energy of about 320mJ at 1.06μm wavelength is focused on the aluminium target mounted on a ballistic pendulum, and the air pressure in the chamber changes from 2.8 × 10^ 3 to 1.01 × 10^5pa. The experimental results show that the impulse coupling coefficient changes as the air pressure and the distance of the target from focus change. The mechanical effects of the plasma shock wave on the target are analysed at different distances from focus and the air pressure.展开更多
AIM To explore the relationship of liver and spleen shear wave velocity in patients with liver cirrhosis combined with portal hypertension,and assess the value of liver and spleen shear wave velocity in predicting the...AIM To explore the relationship of liver and spleen shear wave velocity in patients with liver cirrhosis combined with portal hypertension,and assess the value of liver and spleen shear wave velocity in predicting the prognosis of patients with portal hypertension.METHODS All 67 patients with liver cirrhosis diagnosed as portal hypertension by hepatic venous pressure gradient in our hospital from June 2014 to December 2014 were enrolled into this study. The baseline information of these patients was recorded. Furthermore,67 patients were followed-up at 20 mo after treatment,and liver and spleen shear wave velocity were measured by acoustic radiation force impulse at the 1^(st) week,3^(rd) month and 9^(th) month after treatment. Patients with favorable prognosis were assigned into the favorable prognosis group,while patients with unfavorable prognosis were assigned into the unfavorable prognosis group. The variation and difference in liver and spleen shear wave velocity in these two groups were analyzed by repeated measurement analysis of variance. Meanwhile,in order to evaluate the effect of liver and spleen shear wave velocity on the prognosis of patients with portal hypertension,Cox's proportional hazard regression model analysis was applied. The ability of those factors in predicting the prognosis of patients with portal hypertension was calculated through receiver operating characteristic(ROC) curves.RESULTS The liver and spleen shear wave velocity in the favorable prognosis group revealed a clear decline,while those in the unfavorable prognosis group revealed an increasing tendency at different time points. Furthermore,liver and spleen shear wave velocity was higher in the unfavorable prognosis group,compared with the favorable prognosis group; the differences were statistically significant(P < 0.05). The prognosis of patients with portal hypertension was significantly affected by spleen hardness at the 3^(rd) month after treatment [relative risk(RR) = 3.481]. At the 9^(th) month after treatment,the prognosis was affected by liver hardness(RR = 5.241) and spleen hardness(RR = 7.829). The differences between these two groups were statistically significant(P < 0.05). The ROC analysis revealed that the area under the curve(AUC) of spleen hardness at the 3^(rd) month after treatment was 0.644,while the AUCs of liver and spleen hardness at the 9^(th) month were 0.579 and 0.776,respectively. These might predict the prognosis of patients with portal hypertension.CONCLUSION Spleen hardness at the 3^(rd) month and liver and spleen shear wave velocity at the 9^(th) month may be used to assess the prognosis of patients with portal hypertension. This is hoped to be used as an indicator of predicting the prognosis of patients with portal hypertension.展开更多
BACKGROUND Few systematic comparative studies of the different methods of physical elastography of the spleen are currently available.AIM To compare point shear wave and two-dimensional elastography of the spleen cons...BACKGROUND Few systematic comparative studies of the different methods of physical elastography of the spleen are currently available.AIM To compare point shear wave and two-dimensional elastography of the spleen considering the anatomical location(upper,hilar,and lower pole).METHODS As part of a prospective clinical study,healthy volunteers were examined for splenic elasticity using four different ultrasound devices between May 2015 and April 2017.The devices used for point shear wave elastography were from Siemens(S 3000)and Philips(Epiq 7),and those used for two-dimensional shear wave elastography were from GE(Logiq E9)and Toshiba(Aplio 500).In addition,two different software versions(5.0 and 6.0)were evaluated for the Toshiba ultrasound device(Aplio 500).The study consisted of three arms:A,B,and C.RESULTS In study arm A,200 subjects were evaluated(78 males and 122 females,mean age 27.9±8.1 years).In study arm B,113 subjects were evaluated(38 men and 75 women,mean age 26.0±6.3 years).In study arm C,44 subjects were enrolled.A significant correlation of the shear wave velocities at the upper third of the spleen(r=0.33088,P<0.0001)was demonstrated only for the Philips Epiq 7 device compared to the Siemens Acuson S 3000.In comparisons of the other ultrasound devices(GE,Siemens,Toshiba),no comparable results could be obtained for any anatomical position of the spleen.The influencing factors age,gender,and body mass index did not show a clear correlation with the measured shear wave velocities.CONCLUSION The absolute values of the shear wave elastography measurements of the spleen and the two different elastography methods are not comparable between different manufacturers or models.展开更多
基金supported by National Key R&D Program of China(ID:2018YFC1504803)project from China Geological Survey(Grant No.121201009000150018 and DD20190637)Geological Hazard Prevention and Control Project for Follow-Up Work of the Three Gorges Project(000121 2018C C60 003)
文摘The destructiveness of impulse waves generated by landslides(IWL) originates from the wave’s movement and load, wherein the impulse wave’s load is the major cause of sub-aerial building damage and casualties. In this study, an experiment involving 16 groups of physical tests for the wave pressure generated by a landslide was designed, consisting of 4 sets of IWL and 4 opposite bank slope angles. A high-frequency strain system was used to measure the total pressure of the impulse wave in a water tank. The tests showed that the dynamic pressure caused by the IWL can be divided into two types: impact pressure generated by the jetflow and the pulsating pressure caused by the wave. Under the same impulse wave conditions, the maximum run-up becomes smaller as the opposite bank’s slope angle increases, and the jetflow maximum impact pressure experienced by the opposite bank increases, while the maximum pulsating pressure caused by the impulse wave is slightly decreased. Different from previous studies, the spatial maximum pressure distributions of the wave generated by landslide were concluded that the position of the maximum pulsating pressure appears adjacent to the still water surface, and the overall spatial distribution pattern of maximum wave pressure is presented as an inclined 'M' shape.Meanwhile, this study is the first to quantitatively analyzed that impact pressure has a very short action time, is even 7 times of the pulse pressure value, and there is a simple mathematical linear relationship between the two. Currently, some wave-load formulas for wind waves and tides are not applicable to calculating the loads of IWL. Research on the load of IWL will explain the hazard of impulse wave very clearly, and will greatly contribute to hazard prevention, mitigation and risk assessment work associated with IWL.
基金supported by the National Natural Science Foundation of China(Grant No.51279050)the National High Technology Research Development Program of China(863 Pro-gram,Grant No.2012AA112507)the Non-profit Industry Financial Program of Ministry of Water Resources of China(Grant No.201301058)
文摘A numerical model is proposed for the simulation of impulse waves generated by landslides. The fluid-like landslide is modeled as a generalized non-Newtonian visco-plastic fluid. The conservative level set method is extended to the n-phase flow and applied to capture the interfaces of air, water and landslide. Numerical results show an excellent performance of the current model to capture the whole process of the landslide and the impulse wave generation.
基金support from the National Natural Sciences Foundation of China(Nos.42177159,42077277,41877253)the Fundamental Research Funds for the Central Universities,China University of Geosciences(Wuhan)(No.CUG2106304).
文摘Landslide-generated impulsive waves(LGWs)in reservoir areas can seriously threaten waterway safety as well as hu-man life and properties around the two side slopes.The risk reduction and mitigation of such a hazard require the accurate prediction of near-field wave characteristics,such as wave amplitude and run-up.However,near-field LGW involves complicated fluid-solid interactions.Furthermore,the wave characteristics are closely related to various aspects,including the geometry and physical features of the slide,river,and body of water.However,the empirical or analytical methods used for rough estimation cannot derive accurate results,especially for deformable landslides,due to their significant geometry changes during the sliding process.In this study,the near-field waves generated by deformable landslides were simulated by smoothed particle hydrodynamics(SPH)based on multi-phase flow.The deformable landslides were generalized as a kind of viscous flow by adopting the Herschel-Bulkley-Papanastasiou(HBP)-based nonNewtonian rheology model.The HBP model is capable of producing deformable landslide dynamics even though the high-speed sliding process is involved.In this study,an idealized experiment case originating from Lituya LGW and a practical case of Gongjiafang LGW were reproduced for verification and demonstration.The simulation results of both cases show satisfactory consistency with the experiment/investigation data in terms of landslide movement and near-field impulsive wave characteristics,thus indicating the applicability and accuracy of the proposed method.Finally,the effects of the HBP model’s rheological parameters on the landslide dynamics and near-field wave characteristics are discussed,providing a parameter calibration method along with sug-gestions for further applications.
基金Supported by Science and Technology Foundation of Pudong New District,No.PKJ2015-Y05)Medical and Industrial Interdisciplinary Fund of Shanghai Jiao Tong University,No.YG2016MS30+1 种基金General Program of Shanghai Health and Family Planning Commission,No.201740095Guiding Project of Shanghai Science and Technology Commission,No.19411965400
文摘BACKGROUND Several studies have demonstrated the feasibility and effectiveness of using ultrasound elastography to assess liver tissue stiffness.Virtual touch imaging quantification(VTIQ)based on acoustic radiation force impulse imaging has been developed as a latest and noninvasive method for assessing liver stiffness in children.AIM To determine the standard value in healthy children,and to identify possible factors that might influence the VTIQ measurement.METHODS With the ethical approval,202 children between 1 month and 15 years old were included in this study.None of them had any liver or systematic diseases.All children had a normal ultrasound scan and normal body mass index(BMI)range.The subjects were divided into four age and BMI groups.The effects of gender,age,liver lobe,measurement depth,and BMI on liver elasticity were investigated.RESULTS A significant correlation was found between age and shear wave velocity(SWV)value.At measurement depths of 1.5 cm and 2.0 cm in the left lobe,there were significant differences among the age groups.SWV values were significantly negatively correlated with the measurement depth.Gender,liver lobe,and BMI showed no significant effect on the SWV values.Age and BMI may influence the quality of the elastogram.CONCLUSION VTIQ is a noninvasive technique that is feasible to measure liver stiffness in children.The afore-mentioned velocity value obtained utilizing VTIQ method could be used as reference value for normal liver stiffness in children.
基金financially supported by the National Natural Science Foundation of China(Grant Nos.51279190 and 51311140259)the Shandong Province Natural Science Foundation for Distinguished Young Scholars(Grant No.JQ201314)
文摘Impulse turbine, working as a typical self-rectifying turbine, is recently utilized for the oscillating water column(OWC) wave energy converters, which can rotate in the same direction under the bi-directional air flows. A numerical model established in Fluent is validated by the corresponding experimental results. The flow fields, pressure distribution and dimensionless evaluating coefficients can be calculated and analyzed. Effects of the rotor solidity varying with the change of blade number are investigated and the suitable solidity value is recommended for different flow coefficients.
文摘Wells turbine has inherent disadvantages in comparison with conventional turbines: relative low efficiency at high flow coefficient and poor starting characteristics. To solve these problems, the authors propose Wells turbine with booster turbine for wave energy conversion, in order to improve the performance in this study. This turbine consists of three parts: a large Wells turbine, a small impulse turbine with fixed guide vanes for oscillating airflow, and a generator. It was conjectured that, by coupling the two axial flow turbines together, pneumatic energy from oscillating airflow is captured by Wells turbine at low flow coefficient and that the impulse turbine gets the energy at high flow coefficient. As the first step of this study on the proposed turbine topology, the performance of turbines under steady flow conditions has been investigated experimentally by model testings. Furthermore, we estimate mean efficiency of the turbine by quasi-steady analysis.
文摘A twin unidirectional impulse turbine has been proposed in order to enhance the performance of wave energy plant. This turbine system uses two unidirectional impulse turbines and their flow direction is different each other. However, the effect of guide vane solidity on the turbine characteristics has not been clarified to date. The performances of a uni- directional impulse turbine under steady flow conditions were investigated experimentally by using a wind tunnel with large piston/cylinder in this study. Then, mean efficiency of the twin impulse turbine in bidirectional airflow has been estimated by a quasi-steady analysis using experimental results in order to investigate the effect of guide vane solidity on the performance.
基金This investigation was carried out as a continuation of the“Program for the Promotion of New Energy Infrastructure Development”,supported by the Mitsubishi Research Institute(MRI)/the Ministry of Economy,Trade and Industry(METI),Japan.
文摘A fixed oscillating water column(OWC)-type wave energy converter consists of an air chamber,an air turbine and a generator.The energy conversion processes are the primary conversion in an air chamber and the secondary conversion of the turbine.For the practical use,it is necessary to develop a design method which can consider the incident wave motion,the motion of the internal free surface affected in the structure such as a partly submerged wall,the fluctuation of air pressure in an air chamber,and the rotation of the air turbine.At here,the authors carried out the wave tank tests using the model OWC equipped with the impulse turbine and a generator to obtain the experimental data needed to make this design method.As the result,the efficiencies of the three cases with different speed ratio between generator and turbine,and the effects of the curtain wall depth and the wave length on the energy conversion performance were clarified.
基金Supported by MEXT-Supported Program for the Strategic Research Foundation at Private Universities of the Japanese Governmentthe Ministry of Health,Labor,and Welfare of the Japanese Government
文摘AIM: To investigate the factors other than fibrosis stage correlating with acoustic radiation force impulse (ARFI) elastograpy in chronic hepatitis C.
文摘Objective: The aim of our study was to make the qualitative and quantitative analysis to breast lesions using acoustic radiation force impulses (ARFI), and assess the diagnostic value of ARFI for differentiation between benign and malignant solid breast masses, meanwhile evaluate the influences of ARFI with breast imaging reporting and data system (BI-RADS) of suspicious masses. Methods: Seventy-five women with 86 breast lesions underwent conventional breast ultra- sound examination. Then B-mode BI-RADS features and assessments were recorded and standard breast US supplemented by ARFI elastographic examination were repeated. The data were recorded and analyzed as following: area ratio of breast lesion, the shear-wave velocity, the ratio of the shear-wave velocity between lesions and surrounding normal tissues, and according to the elastographic data reconsidered the BI-RADS category, all the results have been correlated with pathological results and make statistical evaluations of ARFI for differentiation between benign and malignant solid breast masses. Meantime our study has correlated the adjusted BI-RADS category of suspicious breast lesions with the pathological results and made assessment. Results: Thirty-eight patients were malignant breast carcinoma (31 invasive ductal carcinoma, 5 intraductal carcinoma in situ, 2 medullary carcinoma, 2 invasive Iobular carcinoma), 48 patients were benign breast lesions (23 fibroadenoma, 12 benign nodular hyperplasia, 5 phyllodes tumor, 6 adenosis, 2 intraductal papilloma). Underwent conventional breast ultrasound exam, 42 cases were BI-RADS category 3, 23 cases were BI-RADS category 4. When adding elastographic data, 46 cases were BI-RADS category 3 and 20 cases were BI-RADS category 4. Compared with pathological results showed for both the specificity of BIRADS features and the area under ROC curve has risen. Virtual touch tissue imaging (VTI) and virtual touch tissue quantification (VTQ) data showed the area ratio (AR) between elastographic lesions area and B-mode lesions area, SWV (maximal shear-wave velocity of lesions), R-SWV (shear-wave velocity ratio between lesions and surrounding normal tissues) in benign breast lesions were lower than those in malignant lesions which has statistical significance and the cut-off point were 1.1,4.65 m/s, 5.18 respectively. Conclusion: The ARFI elastography can provide the reliable qualitative and quantitative analysis about hardness of breast lesions, supply the new BI-RADS category features to suspicious breast masses and serve as an effective diagnostic tool for differentiation between benign and malignant solid masses.
基金Project supported by the National Natural Science Foundation of China(No.10572002).
文摘By applying the integral transform method and the inverse transformation technique based upon the two types of integration, the present paper has successfully obtained an exact algebraic solution for a two-dimensional Lamb's problem due to a strip impulse loading for the first time. With the algebraic result, the excitation and propagation processes of stress waves, including the longitudinal wave, the transverse wave, and Rayleigh-wave, are discussed in detail. A few new conclusions have been drawn from currently available integral results or computational results.
文摘Wave energy is a renewable source with significant amount in relation to the global demand. A good concept of a device applied to extract this type of energy is the onshore oscillating water column wave energy converter(OWC-WEC). This study shows a numerical analysis of the diameter determination of two types of turbines, Wells and Impulse, installed in an onshore OWC device subjected to a hypothetical sea state. Commercial software FLUENT?,which is based on RANS-VoF(Reynolds-Averaged Navier-Stokes equations and Volume of Fluid technique), is employed. A methodology that imposes air pressure on the chamber, considering the air compressibility effect, is used. The mathematical domain consists of a 10 m deep flume with a 10 m long and 10 m wide OWC chamber at its end(geometry is similar to that of the Pico's plant installed in Azores islands, Portugal). On the top of the chamber, a turbine works with air exhalation and inhalation induced by the water free surface which oscillates due to the incident wave. The hypothetical sea state, represented by a group of regular waves with periods from 6 to 12 s and heights from 1.00 to 2.00 m(each wave with an occurrence frequency), is considered to show the potential of the presented methodology. Maximum efficiency(relation between the average output and incident wave powers) of46% was obtained by using a Wells turbine with the diameter of 2.25 m, whereas the efficiency was 44% by an Impulse turbine with the diameter of 1.70 m.
文摘Neurologists define the transmission of nerve impulses across the membranes of the neural cells as a result of difference in the concentration of ions while they measured an electric potential, called as an action potential, which allows the propagation of such nerve impulses as electrical signals. Such measurements should guide them to a logical explanation of the nerve impulses as electric charges driven by the measured action potential. However, such logical conclusion, or explanation, is ignored due to a wrong definition of the flow of electric charges as a flow of electrons that cannot pass through neural networks. According to recent studies, electric charges are properly defined as electromagnetic (EM) waves whose energy is expressed as the product of its propagating electric potential times their entropy flow which is adhered to the flow of such energy. Such definition matches the logical conclusion of the nerve impulses as electric charges, as previously explained, and defines the entropy of the neural network, measured by Ammeters, in Watt or Joule/Volt. The measured entropy represents a neurodiagnostic property of the neural networks that measures its capacity to allow the flow of energy per unit action potential. Theoretical verification of the innovative definition of nerve impulses is presented by following an advanced entropy approach. A proper review of the machine records of the stimulating electric charges, used in the diagnosis of the neural networks, and the stimulated nerve impulses or stimulated responses, represents practical verifications of the innovative definitions of the electric charges and the nerve impulses. Comparing the functioning of the thermoelectric generators and the brain neurons, such neurons are defined as thermoelectric generators of the electric nerve impulses and their propagating, or action, potential.
文摘Since the CPU of embed system has some limitation in operating speed, a new filter was put forward which implemented mountain template convolution by performing rectangle template convolution two times. It can obtain time and frequency localization with computational complexity greatly reduced. This algorithm was applied to lightning waveforms (include chopped waveforms) parameter calculation. It simplifies the computation and the results pretreated by this algorithm are in accord with IEC1083-2 completely. It was applied in embed system successfully. Its capability in frequency restraining was researched. The validity of the algorithm was proved in theory when processing lightning waves. The standard sources and the processing results are consistent completely.
基金The authors would like thank LI Renjiang and HU Bin from the China Three Gorges Corporation for providing many valuable suggestions for the establishment of the physical models.This work was supported by the National Natural Science Foundation of China(No.U23A2045)the China Three Gorges Corporation(YM(BHT)/(22)022)the Scientific Research Project of Chongqing Municipal Bureau of Planning and Natural Resources(Evaluation and Reinforcement Technology of Surge Disaster Caused by High and Steep Dangerous Rocks in Chongqing Reservoir Area of the Three Gorges Project,KJ-2023046).
文摘The impulse waves induced by large-reservoir landslides can be characterized by a low Froude number.However,systematic research on predictive models specifically targeting the initial primary wave is lacking.Taking the Shuipingzi 1#landslide that occurred in the Baihetan Reservoir area of the Jinsha River in China as an engineering example,this study established a large-scale physical model(with dimensions of 30 m×29 m×3.5 m at a scale of 1:150)and conducted scaled experiments on 3D landslide-induced impulse waves.During the process in which a sliding mass displaced and compressed a body of water to generate waves,the maximum initial wave amplitude was found to be positively correlated with the sliding velocity and the volume of the landslide.With the increase in the water depth,the wave amplitude initially increased and then decreased.The duration of pressure exertion by the sliding mass at its maximum velocity directly correlated with an elevated wave amplitude.Based on the theories of low-amplitude waves and energy conservation,while considering the energy conversion efficiency,a predictive model for the initial wave amplitude was derived.This model could fit and validate the functions of wavelength and wave velocity.The accuracy of the initial wave amplitude was verified using physical experiment data,with a prediction accuracy for the maximum initial wave amplitude reaching 90%.The conversion efficiency(η)directly determined the accuracy of the estimation formula.Under clear conditions for landslide-induced impulse wave generation,estimating the value ofηthrough analogy cases was feasible.This study has derived the landslide-induced impulse waves amplitude prediction formula from the standpoints of wave theory and energy conservation,with greater consideration given to the intrinsic characteristics in the formation process of landslide-induced impulse waves,thereby enhancing the applicability and extensibility of the formula.This can facilitate the development of empirical estimation methods for landslide-induced impulse waves toward universality.
文摘AIM:To investigate whether a noninvasive measurement of tissue strain has a potential usefulness for management of nonalcoholic steatohepatitis(NASH).METHODS:In total 26 patients,23 NASHs and 3 normal controls were enrolled in this study.NASH was staged based on Brunt criterion.At a region of interest(ROI),a shear wave was evoked by implementing an acoustic radiation force impulse(ARFI),and the propagation velocity was quantif ied.RESULTS:Shear wave velocity(SWV) could be reproducibly quantified at all ROIs in all subjects except for 4 NASH cases,in which a reliable SWV value was not calculated at several ROIs.An average SWV of 1.34 ± 0.26 m/s in fibrous stage 0-1 was significantly slower than 2.20 ± 0.74 m/s and 2.90 ± 1.01 m/s in stages 3 and 4,respectively,but was not significantly different from 1.79 ± 0.78 m/s in stage 2.When a cutoff value was set at 1.47 m/s,receiver operating characteristic analysis showed significance to dissociate stages 3 and 4 from stage 0-1(P=0.0092) with sensitivity,specificity and area under curve of 100%,75% and 94.2%,respectively.In addition,the correlation between SWV and hyaluronic acid was significant(P<0.0001),while a tendency toward negative correlation was observed with serum albumin(P=0.053).CONCLUSION:The clinical implementation of ARFI provides noninvasive repeated evaluations of liver stiffness at an arbitrary position,which has the potential to shed new light on NASH management.
文摘BACKGROUND Shear wave speed has been widely applied to quantify a degree of liver fibrosis. However, there is no standardized procedure, which makes it difficult to utilize the speed universally. AIM To provide procedural standardization of shear wave speed measurement. METHODS Point shear wave elastography (pSWE) was measured in 781 patients, and twodimensional shear wave elastography (2dSWE) was measured on the same day in 18 cases. Regions-of-interest were placed at 12 sites, and the median and robust coefficient-of-variation (CVR) were calculated. A residual sum-of-square (Σdi2) was computed for bootstrap values of 1000 iterations in 18 cases with each assumption of 1 to 12 measurements. The proportion of the Σdi2 (%Σdi2) was calculated as the ratio of Σdi2 to pSWE after converting it based on the correlation between pSWE and 2dSWE. RESULTS The CVR showed a significantly broader distribution in the left lobe (P < 0.0001),and the smallest CVR in the right anterior segment that covered 95% cases was 40.4%. pSWE was significantly higher in the left lobe than in the right lobe (1.63 ± 0.78 m/s vs 1.61 ± 0.78 m/s, P = 0.0004), and the difference between the lobes became further discrete when the subjects were limited to the cases with a CVR less than 40.4% in any segment (1.76 ± 0.80 m/s vs 1.70 ± 0.82 m/s, P < 0.0001). The highest values of the CVR in every 0.1 m/s interval were plotted in convex upward along pSWE and peaked at 1.93 m/s. pSWE and 2dSWE were significantly correlated (P < 0.0001, r = 0.95). In 216000 resamples from 18 cases, the %Σdi2 of 12 sites was 8.0% and gradually increased as the acquisition sites decreased to reach a significant difference with a %Σdi2 of 7 sites (P = 0.027). CONCLUSION These data suggest that shear wave speed should be measured at 8 or more sites of spreading in both lobes.
基金Project supported by the National Natural Science Foundation of China (Grant No 60578015).
文摘The influence of air pressure on mechanical effect of laser plasma shock wave in a vacuum chamber produced by a Nd:YAG laser has been studied. The laser pulses with pulse width of 10ns and pulse energy of about 320mJ at 1.06μm wavelength is focused on the aluminium target mounted on a ballistic pendulum, and the air pressure in the chamber changes from 2.8 × 10^ 3 to 1.01 × 10^5pa. The experimental results show that the impulse coupling coefficient changes as the air pressure and the distance of the target from focus change. The mechanical effects of the plasma shock wave on the target are analysed at different distances from focus and the air pressure.
基金Supported by Medical and Health Science and Technology Program of Zhejiang Province,2017,No.2017KY590
文摘AIM To explore the relationship of liver and spleen shear wave velocity in patients with liver cirrhosis combined with portal hypertension,and assess the value of liver and spleen shear wave velocity in predicting the prognosis of patients with portal hypertension.METHODS All 67 patients with liver cirrhosis diagnosed as portal hypertension by hepatic venous pressure gradient in our hospital from June 2014 to December 2014 were enrolled into this study. The baseline information of these patients was recorded. Furthermore,67 patients were followed-up at 20 mo after treatment,and liver and spleen shear wave velocity were measured by acoustic radiation force impulse at the 1^(st) week,3^(rd) month and 9^(th) month after treatment. Patients with favorable prognosis were assigned into the favorable prognosis group,while patients with unfavorable prognosis were assigned into the unfavorable prognosis group. The variation and difference in liver and spleen shear wave velocity in these two groups were analyzed by repeated measurement analysis of variance. Meanwhile,in order to evaluate the effect of liver and spleen shear wave velocity on the prognosis of patients with portal hypertension,Cox's proportional hazard regression model analysis was applied. The ability of those factors in predicting the prognosis of patients with portal hypertension was calculated through receiver operating characteristic(ROC) curves.RESULTS The liver and spleen shear wave velocity in the favorable prognosis group revealed a clear decline,while those in the unfavorable prognosis group revealed an increasing tendency at different time points. Furthermore,liver and spleen shear wave velocity was higher in the unfavorable prognosis group,compared with the favorable prognosis group; the differences were statistically significant(P < 0.05). The prognosis of patients with portal hypertension was significantly affected by spleen hardness at the 3^(rd) month after treatment [relative risk(RR) = 3.481]. At the 9^(th) month after treatment,the prognosis was affected by liver hardness(RR = 5.241) and spleen hardness(RR = 7.829). The differences between these two groups were statistically significant(P < 0.05). The ROC analysis revealed that the area under the curve(AUC) of spleen hardness at the 3^(rd) month after treatment was 0.644,while the AUCs of liver and spleen hardness at the 9^(th) month were 0.579 and 0.776,respectively. These might predict the prognosis of patients with portal hypertension.CONCLUSION Spleen hardness at the 3^(rd) month and liver and spleen shear wave velocity at the 9^(th) month may be used to assess the prognosis of patients with portal hypertension. This is hoped to be used as an indicator of predicting the prognosis of patients with portal hypertension.
文摘BACKGROUND Few systematic comparative studies of the different methods of physical elastography of the spleen are currently available.AIM To compare point shear wave and two-dimensional elastography of the spleen considering the anatomical location(upper,hilar,and lower pole).METHODS As part of a prospective clinical study,healthy volunteers were examined for splenic elasticity using four different ultrasound devices between May 2015 and April 2017.The devices used for point shear wave elastography were from Siemens(S 3000)and Philips(Epiq 7),and those used for two-dimensional shear wave elastography were from GE(Logiq E9)and Toshiba(Aplio 500).In addition,two different software versions(5.0 and 6.0)were evaluated for the Toshiba ultrasound device(Aplio 500).The study consisted of three arms:A,B,and C.RESULTS In study arm A,200 subjects were evaluated(78 males and 122 females,mean age 27.9±8.1 years).In study arm B,113 subjects were evaluated(38 men and 75 women,mean age 26.0±6.3 years).In study arm C,44 subjects were enrolled.A significant correlation of the shear wave velocities at the upper third of the spleen(r=0.33088,P<0.0001)was demonstrated only for the Philips Epiq 7 device compared to the Siemens Acuson S 3000.In comparisons of the other ultrasound devices(GE,Siemens,Toshiba),no comparable results could be obtained for any anatomical position of the spleen.The influencing factors age,gender,and body mass index did not show a clear correlation with the measured shear wave velocities.CONCLUSION The absolute values of the shear wave elastography measurements of the spleen and the two different elastography methods are not comparable between different manufacturers or models.