The China-Myanmar Economic Corridor(CMEC) is an important part of China's Belt and Road Initiative and an important area for global ecology and biodiversity. In this study, the annual and seasonal spatiotemporal p...The China-Myanmar Economic Corridor(CMEC) is an important part of China's Belt and Road Initiative and an important area for global ecology and biodiversity. In this study, the annual and seasonal spatiotemporal patterns of temperature and precipitation in the CMEC over the past century were investigated using linear tendency estimation, the Mann-Kendall mutation test, the T-test, and wavelet analysis based on the monthly mean climatic data from 1901 to 2018 released by the Climatic Research Unit(CRU) of the University of East Anglia, UK. The results show that the CMEC demonstrated a trend of warming and drying over the past 100 years, and the rate of change in Myanmar was stronger than that in Yunnan Province of China. The warming rate was 0.039 ℃/10a. Precipitation decreased at a rate of -6.1 mm/10a. From the perspective of spatial distribution, temperature was high in the central and southern, low in the north of the CMEC, and the high-temperature centers were mainly distributed in the southern plain and river valley. Precipitation decreased from west to east and from south to north of the CMEC. From the perspective of the rate of change, warming was stronger in central and northern CMEC than in southern and northeastern CMEC. The rate of precipitation decline was stronger in the central and western regions than in the eastern region. This study provides a scientific reference for the CMEC to address climate change and ensure sustainable social and economic development and ecological security.展开更多
The Sichuan-Tibet transportation corridor is prone to numerous active faults and frequent strong earthquakes.While extensive studies have individually explored the effect of active faults and strong earthquakes on dif...The Sichuan-Tibet transportation corridor is prone to numerous active faults and frequent strong earthquakes.While extensive studies have individually explored the effect of active faults and strong earthquakes on different engineering structures,their combined effect remains unclear.This research employed multiple physical model tests to investigate the dynamic response of various engineering structures,including tunnels,bridges,and embankments,under the simultaneous influence of cumulative earthquakes and stick-slip misalignment of an active fault.The prototype selected for this study was the Kanding No.2 tunnel,which crosses the Yunongxi fault zone within the Sichuan-Tibet transportation corridor.The results demonstrated that the tunnel,bridge,and embankment exhibited amplification in response to the input seismic wave,with the amplification effect gradually decreasing as the input peak ground acceleration(PGA)increased.The PGAs of different engineering structures were weakened by the fault rupture zone.Nevertheless,the misalignment of the active fault may decrease the overall stiffness of the engineering structure,leading to more severe damage,with a small contribution from seismic vibration.Additionally,the seismic vibration effect might be enlarged with the height of the engineering structure,and the tunnel is supposed to have a smaller PGA and lower dynamic earth pressure compared to bridges and embankments in strong earthquake zones crossing active faults.The findings contribute valuable insights for evaluating the dynamic response of various engineering structures crossing an active fault and provide an experimental reference for secure engineering design in the challenging conditions of the Sichuan-Tibet transportation corridor.展开更多
The annual distribution characteristics of river runoff in arid regions have significant implications for water resource stability and management.Based on the mountain runoff data from 1965 to 2018,this study examines...The annual distribution characteristics of river runoff in arid regions have significant implications for water resource stability and management.Based on the mountain runoff data from 1965 to 2018,this study examines the annual change characteristics of monthly runoff of the Shiyang River Basin,Heihe River Basin,and Shule River Basin in the Hexi Corridor,Northwest China.Many indexes are used and analyzed,including the coefficient of variance,the complete regulation coefficient,the concentration degree and concentration period,the magnitude of change,the skewness coefficient,and the kurtosis coefficient of the annual distribution curves.The results reveal the following:(1)The inhomogeneity of annual runoff distribution in the Taolai River and the rivers to the west of it,except the Shiyou River,show an increasing trend.Conversely,the inhomogeneity of the rivers to the east of the Taolai River generally show a downward trend,but the coefficient of variance value is still very high.(2)In the Shiyang River Basin,the annual distribution of the concentration period is characterized by a relatively discrete pattern.Conversely,the Heihe River Basin exhibits a relatively concentrated pattern,and the distribution pattern of the Shule River Basin is quite different.Notably,all concentration periods in the three basins have shifted backward after the 2000s.(3)The Shiyang River Basin exhibits disordered annual distribution curves of runoff in different years.In contrast,the Heihe River Basin presents a typical‘single-peak’pattern with a prominent right-skewed.The Shule River Basin has regular distribution curves,with a gradually significant‘double-peak’pattern from east to west.Overall,there has been a slight change in runoff in the Shiyang River Basin,while the Heihe River Basin and Shule River Basin have experienced significant increases in runoff.The annual distribution curves of runoff in the Liyuan River and the rivers to the east of it exhibit a gentle peak pattern,and the appearance probability of extreme runoff during the year is low.Conversely,the rivers to the west of the Liyuan River,excluding the Danghe River,display a sharp peak and thick tail pattern,indicating that the appearance probability of extreme runoff during the year is high.These findings have practical implications for the planning and management of water resources in the Hexi Corridor.Moreover,they provide a solid foundation for predicting future changes in regional water resources.展开更多
目的 探讨Cornelia de Lange综合征(Cornelia de Lange syndrome, CdLS)2型双胞胎患儿的临床表型及基因检测结果,明确患儿的致病原因。方法 收集1例CdLS患儿及父母的临床资料,采集外周血进行家系高通量测序分析。结果 患儿具有特殊面容...目的 探讨Cornelia de Lange综合征(Cornelia de Lange syndrome, CdLS)2型双胞胎患儿的临床表型及基因检测结果,明确患儿的致病原因。方法 收集1例CdLS患儿及父母的临床资料,采集外周血进行家系高通量测序分析。结果 患儿具有特殊面容,眉毛浓密,鼻梁高,上唇薄,嘴角下斜。心脏超声提示动脉导管未闭,卵圆孔未闭。凝血及生化检测发现患儿凝血功能异常,低蛋白血症,胆红素升高。遗传代谢病串联质谱筛查未见明显异常;染色体非整倍体分析:染色体组成46,XY,染色体数目正常。家系全外显子组检测发现:患儿、弟弟及母亲均携带SMC1A基因c.897C>G变异,父亲为野生型。参考ACMG变异解读指南,该变异初步判定为可能致病变异。结论 双胞胎均携带SMC1A基因c.897C>G变异位点,该变异为新发变异,扩大了SMC1A基因变异谱,为临床诊断及患儿家系再生育指导提供了重要依据。展开更多
The Sichuan-Tibet transportation corridor is located at the eastern margin of the Qinghai-Tibet Plateau,where the complex topography and geological conditions,developed geo-hazards have severely restricted the plannin...The Sichuan-Tibet transportation corridor is located at the eastern margin of the Qinghai-Tibet Plateau,where the complex topography and geological conditions,developed geo-hazards have severely restricted the planning and construction of major projects.For the long-term prevention and early control of regional seismic landslides,based on analyzing seismic landslide characteristics,the Newmark model was used to carry out the potential seismic landslide hazard assessment with a 50-year beyond probability 10%.The results show that the high seismic landslide hazard is mainly distributed along large active tectonic belts and deep-cut river canyons,and are significantly affected by the active tectonics.The low seismic landslide hazard is mainly distributed in the flat terrain such as the Quaternary basins,broad river valleys,and plateau planation planes.The major east-west linear projects mainly pass through five areas with high seismic landslide hazard:Luding-Kangding section,Yajiang-Xinlong(Yalong river)section,Batang-Baiyu(Jinsha river)section,Basu(Nujiang river)section,and Bomi-Linzhi(eastern Himalaya syntaxis)section.The seismic action of the Bomi-Linzhi section can also induce high-risk geo-hazard chains such as the high-level glacial lake breaks and glacial debris flows.The early prevention of seismic landslides should be strengthened in the areas with high seismic landslide hazard.展开更多
The risk of reactivated ancient landslides in the Sichuan–Tibet transportation corridor in China is significantly increasing,primarily driven by the intensification of engineering activities and the increased frequen...The risk of reactivated ancient landslides in the Sichuan–Tibet transportation corridor in China is significantly increasing,primarily driven by the intensification of engineering activities and the increased frequency of extreme weather events.This escalation has resulted in a considerable number of fatalities and extensive damage to critical engineering infrastructure.However,the factors contributing to the reactivation and modes of destruction of ancient landslides remain unknown.Therefore,it is imperative to systematically analyze the developmental characteristics and failure modes of reactivated ancient landslides to effectively mitigate disaster risks.Based on a combination of data collection,remote sensing interpretation,and field investigations,we delineated the developmental attributes of typical ancient landslides within the study area.These attributes encompass morphological and topographic aspects,material composition,and spatial structure of ancient landslides.Subsequently,we identified the key triggers for the reactivation of ancient landslides,including water infiltration,reservoir hydrodynamics,slope erosion,and excavation,by analyzing representative cases in the study area.Reactivation of ancient landslides is sometimes the result of the cumulative effects of multiple predisposing factors.Furthermore,our investigations revealed that the reactivation of these ancient landslides primarily led to local failures.However,over extended periods of dynamic action,the entire zone may experience gradual creep.We categorized the reactivation modes of ancient landslides into three distinct types based on the reactivation sequences:progressive retreat,backward thrusting,and forward pulling–backward thrusting.This study is of great significance for us to identify ancient landslides,deepen our understanding of the failure modes and risks of reactivated ancient landslides on the eastern margin of the Tibetan Plateau,and formulate effective disaster prevention and mitigation measures.展开更多
This paper deals with the translation strategies of Chinese Culture-Loaded Words from the perspective of adaptation theory.It is based on the translation text of the sixth episode“Silk Road”and the seventh episode“...This paper deals with the translation strategies of Chinese Culture-Loaded Words from the perspective of adaptation theory.It is based on the translation text of the sixth episode“Silk Road”and the seventh episode“Dunhuang”of the documentary Hexi Corridor.Many words with Chinese cultural connotations appear in the subtitles of this documentary.This paper will be divided into four parts.The first part and the second part deal with the basic theories,i.e.,definition of Chinese Culture-Loaded Words and of adaptation theory.The original text is analysed in the third part.This part deals with the background and specifics of the language of the documentary film Hexi Corridor.The fourth part deals with the difficulties encountered by the author in translation practice and the corresponding solutions adopted by the author.The translation difficulties are solved by five translation methods,namely transliteration,loan translation,substitution,interpretation,and adaptation.展开更多
目的对我国NIPBL基因突变的德朗热综合征(Cornelia de Lange syndrome,CdLS)1型患儿进行基因型和表现型分析。方法以知网、万方、PubMed数据库为文献来源,检索建库至2022年9月发表的相关文献。本研究共纳入41例CdLS1型患者,其中1例来自...目的对我国NIPBL基因突变的德朗热综合征(Cornelia de Lange syndrome,CdLS)1型患儿进行基因型和表现型分析。方法以知网、万方、PubMed数据库为文献来源,检索建库至2022年9月发表的相关文献。本研究共纳入41例CdLS1型患者,其中1例来自四川省妇幼保健院儿科个案报道,其余40例均来自文献综述。回顾性分析这41例CdLS1型患者的基因型与表现型特征。结果我国CdLS1型患者临床表现主要为特殊颅面畸形100.0%(41/41)、肢体畸形100.0%(41/41)、智力障碍100.0%(21/21)、矮小症97.1%(33/34),偶有先天性心脏病(5例)、肾囊肿(3例)、隐睾(2例)、腭裂(2例)、癫痫(2例)等表现,尚无合并先天性膈疝病例报道。诊断年龄为生后胎儿期至12岁,产前诊断6.1%(2/33),新生儿期诊断30.3%(10/33)。本研究CdLS1型患儿中移码突变26.8%(11/41)、剪切突变24.4%(10/41)、错义突变22.0%(9/41)、无义突变22.0%(9/41),CdLS1患者基因型与表现型比较结果差异无统计学意义(H=3.005,P=0.391)。结论本研究CdLS1型患者中,经典型80.5%,非经典型14.6%,疑似4.9%,尚未发现基因型与表型相关。总结并分析CdLS1型患者的临床特点和基因分型,可为临床上早期识别和诊断提供参考。展开更多
基金funded by the Natural Science Foundation of China (Grant No. 42271030)Fujian Provincial Funds for Distinguished Young Scientists (Grant No. 2022J06018)Applied Basic Research Programs of Yunnan province (Grant No. 202001BB050073)。
文摘The China-Myanmar Economic Corridor(CMEC) is an important part of China's Belt and Road Initiative and an important area for global ecology and biodiversity. In this study, the annual and seasonal spatiotemporal patterns of temperature and precipitation in the CMEC over the past century were investigated using linear tendency estimation, the Mann-Kendall mutation test, the T-test, and wavelet analysis based on the monthly mean climatic data from 1901 to 2018 released by the Climatic Research Unit(CRU) of the University of East Anglia, UK. The results show that the CMEC demonstrated a trend of warming and drying over the past 100 years, and the rate of change in Myanmar was stronger than that in Yunnan Province of China. The warming rate was 0.039 ℃/10a. Precipitation decreased at a rate of -6.1 mm/10a. From the perspective of spatial distribution, temperature was high in the central and southern, low in the north of the CMEC, and the high-temperature centers were mainly distributed in the southern plain and river valley. Precipitation decreased from west to east and from south to north of the CMEC. From the perspective of the rate of change, warming was stronger in central and northern CMEC than in southern and northeastern CMEC. The rate of precipitation decline was stronger in the central and western regions than in the eastern region. This study provides a scientific reference for the CMEC to address climate change and ensure sustainable social and economic development and ecological security.
基金supported by the National Natural Science Foundation of China(Grant Nos.41825018,41977248,42207219)the Second Tibetan Plateau Scientific Expedition and Research Program(STEP)(Grant No.2019QZKK0904)。
文摘The Sichuan-Tibet transportation corridor is prone to numerous active faults and frequent strong earthquakes.While extensive studies have individually explored the effect of active faults and strong earthquakes on different engineering structures,their combined effect remains unclear.This research employed multiple physical model tests to investigate the dynamic response of various engineering structures,including tunnels,bridges,and embankments,under the simultaneous influence of cumulative earthquakes and stick-slip misalignment of an active fault.The prototype selected for this study was the Kanding No.2 tunnel,which crosses the Yunongxi fault zone within the Sichuan-Tibet transportation corridor.The results demonstrated that the tunnel,bridge,and embankment exhibited amplification in response to the input seismic wave,with the amplification effect gradually decreasing as the input peak ground acceleration(PGA)increased.The PGAs of different engineering structures were weakened by the fault rupture zone.Nevertheless,the misalignment of the active fault may decrease the overall stiffness of the engineering structure,leading to more severe damage,with a small contribution from seismic vibration.Additionally,the seismic vibration effect might be enlarged with the height of the engineering structure,and the tunnel is supposed to have a smaller PGA and lower dynamic earth pressure compared to bridges and embankments in strong earthquake zones crossing active faults.The findings contribute valuable insights for evaluating the dynamic response of various engineering structures crossing an active fault and provide an experimental reference for secure engineering design in the challenging conditions of the Sichuan-Tibet transportation corridor.
基金This research was funded by the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB0720200)the Gansu Provincial Science and Technology Planning Project(23ZDFA018)+4 种基金the National Key R&D Program of China(Project No.2022YFF1303301)the“Light of West China”Program of CAS(Project Nos.xbzglzb202020,23JR6KA008)Science and technology project of Gansu Province(Project No.21JR7RA046)the Natural Science Foundation of China(Project No.52179026)the Open Foundation of State Key Laboratory of Computer Science(Project No.SKLCS 2020–05).
文摘The annual distribution characteristics of river runoff in arid regions have significant implications for water resource stability and management.Based on the mountain runoff data from 1965 to 2018,this study examines the annual change characteristics of monthly runoff of the Shiyang River Basin,Heihe River Basin,and Shule River Basin in the Hexi Corridor,Northwest China.Many indexes are used and analyzed,including the coefficient of variance,the complete regulation coefficient,the concentration degree and concentration period,the magnitude of change,the skewness coefficient,and the kurtosis coefficient of the annual distribution curves.The results reveal the following:(1)The inhomogeneity of annual runoff distribution in the Taolai River and the rivers to the west of it,except the Shiyou River,show an increasing trend.Conversely,the inhomogeneity of the rivers to the east of the Taolai River generally show a downward trend,but the coefficient of variance value is still very high.(2)In the Shiyang River Basin,the annual distribution of the concentration period is characterized by a relatively discrete pattern.Conversely,the Heihe River Basin exhibits a relatively concentrated pattern,and the distribution pattern of the Shule River Basin is quite different.Notably,all concentration periods in the three basins have shifted backward after the 2000s.(3)The Shiyang River Basin exhibits disordered annual distribution curves of runoff in different years.In contrast,the Heihe River Basin presents a typical‘single-peak’pattern with a prominent right-skewed.The Shule River Basin has regular distribution curves,with a gradually significant‘double-peak’pattern from east to west.Overall,there has been a slight change in runoff in the Shiyang River Basin,while the Heihe River Basin and Shule River Basin have experienced significant increases in runoff.The annual distribution curves of runoff in the Liyuan River and the rivers to the east of it exhibit a gentle peak pattern,and the appearance probability of extreme runoff during the year is low.Conversely,the rivers to the west of the Liyuan River,excluding the Danghe River,display a sharp peak and thick tail pattern,indicating that the appearance probability of extreme runoff during the year is high.These findings have practical implications for the planning and management of water resources in the Hexi Corridor.Moreover,they provide a solid foundation for predicting future changes in regional water resources.
文摘目的 探讨Cornelia de Lange综合征(Cornelia de Lange syndrome, CdLS)2型双胞胎患儿的临床表型及基因检测结果,明确患儿的致病原因。方法 收集1例CdLS患儿及父母的临床资料,采集外周血进行家系高通量测序分析。结果 患儿具有特殊面容,眉毛浓密,鼻梁高,上唇薄,嘴角下斜。心脏超声提示动脉导管未闭,卵圆孔未闭。凝血及生化检测发现患儿凝血功能异常,低蛋白血症,胆红素升高。遗传代谢病串联质谱筛查未见明显异常;染色体非整倍体分析:染色体组成46,XY,染色体数目正常。家系全外显子组检测发现:患儿、弟弟及母亲均携带SMC1A基因c.897C>G变异,父亲为野生型。参考ACMG变异解读指南,该变异初步判定为可能致病变异。结论 双胞胎均携带SMC1A基因c.897C>G变异位点,该变异为新发变异,扩大了SMC1A基因变异谱,为临床诊断及患儿家系再生育指导提供了重要依据。
基金supported by the National Natural Science Foundation of China(42277180)China Geological Survey Project(DD20221816)+1 种基金National Key Research and Development Program of China(2021YFB2301403-5)State Key Laboratory of Resources and Environmental Information System.
文摘The Sichuan-Tibet transportation corridor is located at the eastern margin of the Qinghai-Tibet Plateau,where the complex topography and geological conditions,developed geo-hazards have severely restricted the planning and construction of major projects.For the long-term prevention and early control of regional seismic landslides,based on analyzing seismic landslide characteristics,the Newmark model was used to carry out the potential seismic landslide hazard assessment with a 50-year beyond probability 10%.The results show that the high seismic landslide hazard is mainly distributed along large active tectonic belts and deep-cut river canyons,and are significantly affected by the active tectonics.The low seismic landslide hazard is mainly distributed in the flat terrain such as the Quaternary basins,broad river valleys,and plateau planation planes.The major east-west linear projects mainly pass through five areas with high seismic landslide hazard:Luding-Kangding section,Yajiang-Xinlong(Yalong river)section,Batang-Baiyu(Jinsha river)section,Basu(Nujiang river)section,and Bomi-Linzhi(eastern Himalaya syntaxis)section.The seismic action of the Bomi-Linzhi section can also induce high-risk geo-hazard chains such as the high-level glacial lake breaks and glacial debris flows.The early prevention of seismic landslides should be strengthened in the areas with high seismic landslide hazard.
基金supported by the National Natural Science Foundation of China(No.42207233,41731287)the National Key Research and Development Program of China(No.2021YFC3000505)the China Geological Survey projects(No.DD20221816)。
文摘The risk of reactivated ancient landslides in the Sichuan–Tibet transportation corridor in China is significantly increasing,primarily driven by the intensification of engineering activities and the increased frequency of extreme weather events.This escalation has resulted in a considerable number of fatalities and extensive damage to critical engineering infrastructure.However,the factors contributing to the reactivation and modes of destruction of ancient landslides remain unknown.Therefore,it is imperative to systematically analyze the developmental characteristics and failure modes of reactivated ancient landslides to effectively mitigate disaster risks.Based on a combination of data collection,remote sensing interpretation,and field investigations,we delineated the developmental attributes of typical ancient landslides within the study area.These attributes encompass morphological and topographic aspects,material composition,and spatial structure of ancient landslides.Subsequently,we identified the key triggers for the reactivation of ancient landslides,including water infiltration,reservoir hydrodynamics,slope erosion,and excavation,by analyzing representative cases in the study area.Reactivation of ancient landslides is sometimes the result of the cumulative effects of multiple predisposing factors.Furthermore,our investigations revealed that the reactivation of these ancient landslides primarily led to local failures.However,over extended periods of dynamic action,the entire zone may experience gradual creep.We categorized the reactivation modes of ancient landslides into three distinct types based on the reactivation sequences:progressive retreat,backward thrusting,and forward pulling–backward thrusting.This study is of great significance for us to identify ancient landslides,deepen our understanding of the failure modes and risks of reactivated ancient landslides on the eastern margin of the Tibetan Plateau,and formulate effective disaster prevention and mitigation measures.
基金Research Startup Project for Doctors at the School of Foreign Languages,University of Shanghai for Science and Technology(Fund Project No.:1F-21-305-101).
文摘This paper deals with the translation strategies of Chinese Culture-Loaded Words from the perspective of adaptation theory.It is based on the translation text of the sixth episode“Silk Road”and the seventh episode“Dunhuang”of the documentary Hexi Corridor.Many words with Chinese cultural connotations appear in the subtitles of this documentary.This paper will be divided into four parts.The first part and the second part deal with the basic theories,i.e.,definition of Chinese Culture-Loaded Words and of adaptation theory.The original text is analysed in the third part.This part deals with the background and specifics of the language of the documentary film Hexi Corridor.The fourth part deals with the difficulties encountered by the author in translation practice and the corresponding solutions adopted by the author.The translation difficulties are solved by five translation methods,namely transliteration,loan translation,substitution,interpretation,and adaptation.
文摘目的对我国NIPBL基因突变的德朗热综合征(Cornelia de Lange syndrome,CdLS)1型患儿进行基因型和表现型分析。方法以知网、万方、PubMed数据库为文献来源,检索建库至2022年9月发表的相关文献。本研究共纳入41例CdLS1型患者,其中1例来自四川省妇幼保健院儿科个案报道,其余40例均来自文献综述。回顾性分析这41例CdLS1型患者的基因型与表现型特征。结果我国CdLS1型患者临床表现主要为特殊颅面畸形100.0%(41/41)、肢体畸形100.0%(41/41)、智力障碍100.0%(21/21)、矮小症97.1%(33/34),偶有先天性心脏病(5例)、肾囊肿(3例)、隐睾(2例)、腭裂(2例)、癫痫(2例)等表现,尚无合并先天性膈疝病例报道。诊断年龄为生后胎儿期至12岁,产前诊断6.1%(2/33),新生儿期诊断30.3%(10/33)。本研究CdLS1型患儿中移码突变26.8%(11/41)、剪切突变24.4%(10/41)、错义突变22.0%(9/41)、无义突变22.0%(9/41),CdLS1患者基因型与表现型比较结果差异无统计学意义(H=3.005,P=0.391)。结论本研究CdLS1型患者中,经典型80.5%,非经典型14.6%,疑似4.9%,尚未发现基因型与表型相关。总结并分析CdLS1型患者的临床特点和基因分型,可为临床上早期识别和诊断提供参考。