Objective:This study aims to evaluate the surgical morbidity and obstetric outcomes following in-pregnancy or pre-pregnancy laparoscopic abdominal cerclage(LAC)for patients who were diagnosed with refractory cervical ...Objective:This study aims to evaluate the surgical morbidity and obstetric outcomes following in-pregnancy or pre-pregnancy laparoscopic abdominal cerclage(LAC)for patients who were diagnosed with refractory cervical insufficiency or had a short cervix.Methods:A retrospective study was conducted on patients undergoing LAC between May 2017 and May 2019 at the Department of Obstetrics and Gynecology,Sir Run Run Shaw Hospital.The patients were diagnosed with refractory cervical insufficiency based upon a previous failed transvaginal cervical cerclage(TVC),or had a short cervix who were considered unsuitable for a TVC after a previous cervical procedure.All patients were followed-up after surgery with transperineal ultrasonography until May 2020.Subsequently,surgical and obstetric data were collected and analyzed.Results:In total,44 patients underwent LAC,with 8 patients in-pregnancy and 36 pre-pregnancy.For the patient with pre-pregancy LAC,the pregnancy rate was 80.6%(29/36),including 3 patients with first-trimester loss,1 patient with an ectopic pregnancy,and 25 patients with a delivery.For the remaining 7 patients,3 did not conceive,and another 4 had no pregnancy plans.All the patients with in-pregnancy LAC had a delivery.The“take-home baby”rate was 89.2%(33/37),with a live-birth rate of 100%and a neonatal survival rate of 100%for both patients with in-pregnancy and pre-pregnancy LAC.For patients with in-pregnancy LAC,75.0%(6/8)patients delivered at≥37 wk of gestation,12.5%(1/8)delivered between 34 and 36^(+6)wk,and 12.5%(1/8)delivered between 28 and 33^(+6)wk.For patients with pre-pregnancy LAC,80.0%(20/25)patients delivered at≥37 wk of gestation,16.0%(4/25)delivered between 34 and 36^(+6)wk,and 4.0%(1/25)delivered between 28 and 33^(+6)wk.No adverse-event intra-operative or post-operative sequelae were noted.Conclusions:LAC is an effective and safe procedure that results in remarkable obstetric outcomes for women with refractory cervical insufficiency,or with a short cervix who are considered unsuitable for a TVC.The success rate of in-pregnancy or pre-pregnancy LAC depends on a full evaluation of patients,a proper peri-operative management and close follow-up.展开更多
To editor:Cervical insufficiency,or cervical incompetence,is characterized by painless cervix dilatation during the second trimester without contractions.1 It is found in 0.1%–1%of all pregnancies and in up to 8.0%of...To editor:Cervical insufficiency,or cervical incompetence,is characterized by painless cervix dilatation during the second trimester without contractions.1 It is found in 0.1%–1%of all pregnancies and in up to 8.0%of women with recurrent second-trimester miscarriages.2–4 Cervical insufficiency is associated with premature birth,which is a leading cause of neonatal and perinatal mortality and morbidity.展开更多
Uterus didelphys occurs in~0.4%of females and is found in~11%-20%of all uterus defects.It is a risk factor for cervical insufficiency,consequently contributing to late miscarriage or preterm birth.Thus far,only two pr...Uterus didelphys occurs in~0.4%of females and is found in~11%-20%of all uterus defects.It is a risk factor for cervical insufficiency,consequently contributing to late miscarriage or preterm birth.Thus far,only two prior cases of uterus didelphys accompanied by cervical insufficiency treated through laparoscopic cervical cerclage have been reported;however,livebirth only occurred in one hemiuterus.Herein,we report a case of uterus didelphys in a patient diagnosed with cervical insufficiency.Following the placement of a modified laparoscopic cervical cerclage,the patient had two successful livebirths through both hemiuteruses,respectively,with longer gestation age(ie,>36 weeks).The aim of this case report was to provide useful information for clinical practitioners to make better decisions on the management of cervical insufficiency in patients with uterus didelphys,and identify obstetric complications that clinicians should pay attention to during pregnancy.展开更多
目的观察宫颈环扎手术治疗中期妊娠宫颈机能不全的临床效果。方法回顾性分析2012年1月~2018年3月48例中期妊娠诊断为宫颈机能不全行宫颈环扎术的临床资料,观察患者术后情况[术后保胎时间、术后并发症(1周内阴道出血、胎膜早破、感染)]...目的观察宫颈环扎手术治疗中期妊娠宫颈机能不全的临床效果。方法回顾性分析2012年1月~2018年3月48例中期妊娠诊断为宫颈机能不全行宫颈环扎术的临床资料,观察患者术后情况[术后保胎时间、术后并发症(1周内阴道出血、胎膜早破、感染)]、妊娠结局(活产率、延长妊娠孕周、分娩孕周)及新生儿预后(出生体重及Apgar评分)。结果术后保胎时间(8.2±5.7)d。术后1周内阴道出血率33.3%(16/48)、胎膜早破率14.6%(7/48),感染率10.4%(5/48)。≥37孕周分娩22例,28~37孕周16例,<28孕周难免流产10例。围生儿存活率为86.8%(33/38),33例新生儿1 min Apgar评分7~10分,出生体重(2415±207)g,低出生体质量儿5例。结论对中期妊娠出现宫颈功能不全行宫颈环扎术可以有效改善患者的妊娠结局,根据患者自身情况个体化选择手术方式才能达到最佳疗效。展开更多
目的:探讨"经阴道拆除式"腹腔镜下宫颈环扎术(MLTCC)的临床可行性及其优势。方法:收集2012年4月至2018年12月在山东大学齐鲁医院行腹腔镜下宫颈环扎术(LTCC)的90例患者的临床资料和手术视频。按手术方式分为传统腹腔镜下宫颈...目的:探讨"经阴道拆除式"腹腔镜下宫颈环扎术(MLTCC)的临床可行性及其优势。方法:收集2012年4月至2018年12月在山东大学齐鲁医院行腹腔镜下宫颈环扎术(LTCC)的90例患者的临床资料和手术视频。按手术方式分为传统腹腔镜下宫颈环扎术组(TLTCC组,77例)和MLTCC组(13例),回顾分析两组患者的基本临床特征、手术相关指标、术后妊娠情况、分娩方式和新生儿情况,采用卡方检验、非参数秩和检验对数据统计分析。结果:与TLTCC组相比,MLTCC组的单纯宫颈环扎时间明显缩短[18min(12～30min) vs 21min(9～50min),P=0.04],术后妊娠分娩的剖宫产率显著降低(0%vs 100%,P<0.001)。两组的手术总时间、术中出血总量、单纯宫颈环扎出血量、白细胞计数、中性粒细胞比例、住院总天数、术后住院天数、单纯行LTCC的住院费用、止痛药物使用、围术期并发症、环扎带与周围组织重度粘连发生率、妊娠期并发症、妊娠期保胎治疗率、分娩孕周比较,差异均无统计学意义(P>0.05)。结论:MLTCC保留了传统腹腔镜下宫颈环扎术的优点,缩短了宫颈环扎的手术时间,降低了因环扎术所致的剖宫产分娩率。展开更多
基金supported by the Natural Science Foundation of Zhejiang Province(LGF20H180013).
文摘Objective:This study aims to evaluate the surgical morbidity and obstetric outcomes following in-pregnancy or pre-pregnancy laparoscopic abdominal cerclage(LAC)for patients who were diagnosed with refractory cervical insufficiency or had a short cervix.Methods:A retrospective study was conducted on patients undergoing LAC between May 2017 and May 2019 at the Department of Obstetrics and Gynecology,Sir Run Run Shaw Hospital.The patients were diagnosed with refractory cervical insufficiency based upon a previous failed transvaginal cervical cerclage(TVC),or had a short cervix who were considered unsuitable for a TVC after a previous cervical procedure.All patients were followed-up after surgery with transperineal ultrasonography until May 2020.Subsequently,surgical and obstetric data were collected and analyzed.Results:In total,44 patients underwent LAC,with 8 patients in-pregnancy and 36 pre-pregnancy.For the patient with pre-pregancy LAC,the pregnancy rate was 80.6%(29/36),including 3 patients with first-trimester loss,1 patient with an ectopic pregnancy,and 25 patients with a delivery.For the remaining 7 patients,3 did not conceive,and another 4 had no pregnancy plans.All the patients with in-pregnancy LAC had a delivery.The“take-home baby”rate was 89.2%(33/37),with a live-birth rate of 100%and a neonatal survival rate of 100%for both patients with in-pregnancy and pre-pregnancy LAC.For patients with in-pregnancy LAC,75.0%(6/8)patients delivered at≥37 wk of gestation,12.5%(1/8)delivered between 34 and 36^(+6)wk,and 12.5%(1/8)delivered between 28 and 33^(+6)wk.For patients with pre-pregnancy LAC,80.0%(20/25)patients delivered at≥37 wk of gestation,16.0%(4/25)delivered between 34 and 36^(+6)wk,and 4.0%(1/25)delivered between 28 and 33^(+6)wk.No adverse-event intra-operative or post-operative sequelae were noted.Conclusions:LAC is an effective and safe procedure that results in remarkable obstetric outcomes for women with refractory cervical insufficiency,or with a short cervix who are considered unsuitable for a TVC.The success rate of in-pregnancy or pre-pregnancy LAC depends on a full evaluation of patients,a proper peri-operative management and close follow-up.
基金This work was supported by the National Key Research and Development Program of China(no.2021YFC2700700).
文摘To editor:Cervical insufficiency,or cervical incompetence,is characterized by painless cervix dilatation during the second trimester without contractions.1 It is found in 0.1%–1%of all pregnancies and in up to 8.0%of women with recurrent second-trimester miscarriages.2–4 Cervical insufficiency is associated with premature birth,which is a leading cause of neonatal and perinatal mortality and morbidity.
文摘Uterus didelphys occurs in~0.4%of females and is found in~11%-20%of all uterus defects.It is a risk factor for cervical insufficiency,consequently contributing to late miscarriage or preterm birth.Thus far,only two prior cases of uterus didelphys accompanied by cervical insufficiency treated through laparoscopic cervical cerclage have been reported;however,livebirth only occurred in one hemiuterus.Herein,we report a case of uterus didelphys in a patient diagnosed with cervical insufficiency.Following the placement of a modified laparoscopic cervical cerclage,the patient had two successful livebirths through both hemiuteruses,respectively,with longer gestation age(ie,>36 weeks).The aim of this case report was to provide useful information for clinical practitioners to make better decisions on the management of cervical insufficiency in patients with uterus didelphys,and identify obstetric complications that clinicians should pay attention to during pregnancy.
文摘目的观察宫颈环扎手术治疗中期妊娠宫颈机能不全的临床效果。方法回顾性分析2012年1月~2018年3月48例中期妊娠诊断为宫颈机能不全行宫颈环扎术的临床资料,观察患者术后情况[术后保胎时间、术后并发症(1周内阴道出血、胎膜早破、感染)]、妊娠结局(活产率、延长妊娠孕周、分娩孕周)及新生儿预后(出生体重及Apgar评分)。结果术后保胎时间(8.2±5.7)d。术后1周内阴道出血率33.3%(16/48)、胎膜早破率14.6%(7/48),感染率10.4%(5/48)。≥37孕周分娩22例,28~37孕周16例,<28孕周难免流产10例。围生儿存活率为86.8%(33/38),33例新生儿1 min Apgar评分7~10分,出生体重(2415±207)g,低出生体质量儿5例。结论对中期妊娠出现宫颈功能不全行宫颈环扎术可以有效改善患者的妊娠结局,根据患者自身情况个体化选择手术方式才能达到最佳疗效。
文摘目的:探讨"经阴道拆除式"腹腔镜下宫颈环扎术(MLTCC)的临床可行性及其优势。方法:收集2012年4月至2018年12月在山东大学齐鲁医院行腹腔镜下宫颈环扎术(LTCC)的90例患者的临床资料和手术视频。按手术方式分为传统腹腔镜下宫颈环扎术组(TLTCC组,77例)和MLTCC组(13例),回顾分析两组患者的基本临床特征、手术相关指标、术后妊娠情况、分娩方式和新生儿情况,采用卡方检验、非参数秩和检验对数据统计分析。结果:与TLTCC组相比,MLTCC组的单纯宫颈环扎时间明显缩短[18min(12～30min) vs 21min(9～50min),P=0.04],术后妊娠分娩的剖宫产率显著降低(0%vs 100%,P<0.001)。两组的手术总时间、术中出血总量、单纯宫颈环扎出血量、白细胞计数、中性粒细胞比例、住院总天数、术后住院天数、单纯行LTCC的住院费用、止痛药物使用、围术期并发症、环扎带与周围组织重度粘连发生率、妊娠期并发症、妊娠期保胎治疗率、分娩孕周比较,差异均无统计学意义(P>0.05)。结论:MLTCC保留了传统腹腔镜下宫颈环扎术的优点,缩短了宫颈环扎的手术时间,降低了因环扎术所致的剖宫产分娩率。
