Laser Ablation ICP-MS Titanite U-Th-Pb Dating of the Tonglushan Cu-Fe-Au Skarn Deposit,Southeastern Hubei Province

Titanite(CaTi2SiO5) is an important accessory mineral not only in magmatic and metamorphic rocks,but also commonly in hydrothermal mineral deposits. It incorporates appreciable amounts(usually 10×10-6 s to 100×10-6 s) of U and Th into its structure and has a closure temperature of Pb diffusion higher than 660～700 ℃(Scott and St-Onge,1995) ,making it an ideal U-Th-Pb geochronometer. The Daye metallogenic district is located in the west of the giant Middle-Lower Yangtze River(MLYR) Cu-Fe-Au province,eastern China and is well endowed with Fe,Cu,and polymetallic skarn deposits.

Effect of sample temperature on femtosecond laser ablation of copper

We conduct an experimental study supported by theoretical analysis of single laser ablating copper to investigate the interactions between laser and material at different sample temperatures,and predict the changes of ablation morphology and lattice temperature.For investigating the effect of sample temperature on femtosecond laser processing,we conduct experiments on and simulate the thermal behavior of femtosecond laser irradiating copper by using a two-temperature model.The simulation results show that both electron peak temperature and the relaxation time needed to reach equilibrium increase as initial sample temperature rises.When the sample temperature rises from 300 K to 600 K,the maximum lattice temperature of the copper surface increases by about 6500 K under femtosecond laser irradiation,and the ablation depth increases by 20%.The simulated ablation depths follow the same general trend as the experimental values.This work provides some theoretical basis and technical support for developing femtosecond laser processing in the field of metal materials.

Transperineal laser ablation of the prostate as a treatment for benign prostatic hyperplasia and prostate cancer: The results of a Delphi consensus project

Objective: To evaluate transperineal laser ablation (TPLA) with Echolaser® (Echolaser® TPLA, Elesta S.p.A., Calenzano, Italy) as a treatment for benign prostatic hyperplasia (BPH) and prostate cancer (PCa) using the Delphi consensus method.Methods: Italian and international experts on BPH and PCa participated in a collaborative consensus project. During two rounds, they expressed their opinions on Echolaser® TPLA for the treatment of BPH and PCa answering online questionnaires on indications, methodology, and potential complications of this technology. Level of agreement or disagreement to reach consensus was set at 75%. If the consensus was not achieved, questions were modified after each round. A final round was performed during an online meeting, in which results were discussed and finalized.Results: Thirty-two out of forty invited experts participated and consensus was reached on all topics. Agreement was achieved on recommending Echolaser® TPLA as a treatment of BPH in patients with ample range of prostate volume, from <40 mL (80%) to >80 mL (80%), comorbidities (100%), antiplatelet or anticoagulant treatment (96%), indwelling catheter (77%), and strong will of preserving ejaculatory function (100%). Majority of respondents agreed that Echolaser® TPLA is a potential option for the treatment of localized PCa (78%) and recommended it for low-risk PCa (90%). During the final round, experts concluded that it can be used for intermediate-risk PCa and it should be proposed as an effective alternative to radical prostatectomy for patients with strong will of avoiding urinary incontinence and sexual dysfunction. Almost all participants agreed that the transperineal approach of this organ-sparing technique is safer than transrectal and transurethral approaches typical of other techniques (97% of agreement among experts). Pre-procedural assessment, technical aspects, post-procedural catheterization, pharmacological therapy, and expected outcomes were discussed, leading to statements and recommendations.Conclusion: Echolaser® TPLA is a safe and effective procedure that treats BPH and localized PCa with satisfactory functional and sexual outcomes.

GHz bursts in MHz burst(BiBurst) enabling high-speed femtosecond laser ablation of silicon due to prevention of air ionization

For the practical use of femtosecond laser ablation, inputs of higher laser intensity are preferred to attain high-throughput material removal. However, the use of higher laser intensities for increasing ablation rates can have detrimental effects on ablation quality due to excess heat generation and air ionization. This paper employs ablation using BiBurst femtosecond laser pulses, which consist of multiple bursts(2 and 5 bursts) at a repetition rate of 64 MHz, each containing multiple intra-pulses(2–20 pulses) at an ultrafast repetition rate of 4.88 GHz, to overcome these conflicting conditions. Ablation of silicon substrates using the BiBurst mode with 5 burst pulses and 20 intra-pulses successfully prevents air breakdown at packet energies higher than the pulse energy inducing the air ionization by the conventional femtosecond laser pulse irradiation(single-pulse mode). As a result, ablation speed can be enhanced by a factor of23 without deteriorating the ablation quality compared to that by the single-pulse mode ablation under the conditions where the air ionization is avoided.

The Antibacterial Activities of Copper Oxide Nanoparticles Synthesized Using Laser Ablation in Different Surfactants against Streptococcus mutans

Copper oxide nanoparticles(CuO NPs)were synthesised with laser ablation of a copper sheet immersed in deionized water(DW),cetrimonium bromide(CTAB),and sodium dodecyl sulphate(SDS),respectively.The target was irradiated with a pulsed Nd:YAG laser at 1064 nm,600 mJ,a pulse duration of 10 ns,and a repetition rate of 5 Hz.The CuO NPs colloidal were analyzed using UV–Vis spectroscopy,the Fourier transform infrared(FTIR)spectrometer,zeta potential(ZP),X-ray diffraction(XRD),transmission electron microscope(TEM)and field emission scanning electron microscopy(FESEM).The absorption spectra of CuO NPs colloidal showed peaks at 214,215 and 220 nm and low-intensity peaks at 645,650 and 680 nm for SDS,CTAB and DW,respectively.CuO NPs’colloidal results are(−21.6,1.2,and 80 mV)for negatively,neutrally,and positively charged SDS,DW,and CTAB,respectively.The XRD pattern of the NPs revealed the presence of CuO phase planes(110)(111),(20-2)and(11-1).The TEM images revealed nearly spherical NPs,with sizes ranging from 10–90,10–50,and 10–210 nm for CuO NPs mixed with DW,SDS and CTAB,respectively.FESEM images of all the synthesized samples illustrate the formation of spherical nanostructure and large particles are observable.The CuO NPs were tested for antibacterial activity against Streptococcus mutans by using the well diffusion method.In this method,CuO NPs prepared in DW at a concentration of 200μg/mL showed a greater inhibition zone against Streptococcus mutans.

Structural Analysis of TiC and TiC-C Core-Shell Nanostructures Produced by Pulsed-Laser Ablation

This paper reports on the ablation process of a pure Ti solid target immersed in a C-enriched acetone solution, leading to the production of titanium carbide (TiC) and Ti-C core-shell nanostructures. The used route of synthesis is generally called pulsed laser ablation in liquid (PLAL). The presence of carbon structures in the solution contributed to the carbon content in the produced Ti-based nanomaterials. The atomic composition of the produced nanostructures was analyzed using SEM-EDS, while TEM micrographs revealed the formation of spherical TiC and core-shell nanostructures ranging from 40 to 100 nm. The identification of atomic planes by HRTEM confirmed a 10 nm diameter C-shell with a graphite structure surrounding the Ti-core. Raman spectroscopy allowed for the identification of D and G peaks for graphite and a Raman signal at 380 and 600 cm−1, assigned to TiC. The results contribute to the state-of-the-art production of TiC and Ti-C core-shell nanostructures using the PLAL route.

Tracking chloride and metal diffusion in proofed and unproofed concrete matrices using ablative laser technology (ICP-MS)

Depth profiling studies (laser ICP-MS) of ions (Cl-, Na+, Mg2+) in concrete-based material can be used to provide useful information on the migration paths of these ionic species. In particular, deterioration of concrete through infiltration of chloride could lead to costly corrosion problems with serious impact on the environment. Many modeling studies on concrete matrices depend on the tortuosity of these transport paths. Our work showed that dispersion paths of ionic species in concrete are intermittent and sporadic, suggesting that applications of simplifying assumptions in treatment of such data could lead to appreciable perturbations in related mathematical models. This paper examines the capability of using a high resolution ICP-MS laser ablation technique to track Cl– migration in concrete samples in the presence of other ions such as Na+ and Mg2+. Cationic migration in such materials is underexplored and data in this particular area could contribute to modeling studies. Concrete bricks (with and without surface coatings) were specially prepared in cubic configurations and allowed to saturate in a ponding medium (sea water). The study subsequently examined the distribution of Cl– , Na+ and Mg2+ with depth in protected (epoxy coated) and unprotected cored concrete slivers (5 mm diameter;2 mm thick) using an 80 μm- diameter laser beam coupled to an ICP-MS instrument. The laser (213 nm) was programmed to ablate a total depth of 50 μm at each point at 5-μm intervals. The results in unprotected samples indicated that chloride intensity showed a general decline with depth, suggesting that mobility of the chloride is a function of its interaction with the concrete matrix. In some cases ‘hotspots’ were observed at certain points indicating that transport of the intruding ion was limited. No significant mobility was observed in coated samples. The depth-profiling results for Na+ and Mg2+ were somewhat unexpected. Strong similarities in their spectra purported that the matrix was indifferent to charge and size of the ion. Our experimental data further showed that the matrix itself offers natural protection to the reinforced steel rebars by limiting chloride and metal diffusion at certain locations. Clearly, if the composition of these protective environments within the concrete could be simulated on a larger scale and introduced into the matrix it would offer scope for extended research in this area. Our work would be of definite interest to materials and environmental research;and mechanistic studies on aggregates.

Laser ablation for small hepatocellular carcinoma: State of the art and future perspectives

During the last two decades, various local thermal ablative techniques for the treatment of unresectable hepatocellular carcinoma(HCC) have been developed. According to internationally endorsed guidelines, percutaneous thermal ablation is the mainstay of treatment in patients with small HCC who are not candidates for surgical resection or transplantation. Laser ablation(LA) represents one of currently available loco-ablative techniques. In this article, the general principles, technique, image guidance, and patient selection are reported. Primary effectiveness, long-term outcome, and complications are also discussed. A review of published data suggests that LA is equivalent to the more popular and widespread radiofrequency ablation in both local tumor control and long-term outcome in the percutaneous treatment of early HCC. In addition, the LA technique using multiple thin laser fibres allows improved ablative effectiveness in HCCs greater than 3 cm. Reference centres should be equipped with all the available techniques so as to be able to use the best and the most suitable procedure for each type of lesion for each patient.

The characteristics of confined ablation in laser propulsion

Compared with direct ablation, confined ablation provides an effective way to obtain a large target momentum and a high coupling coefficient. By using a transparent glass layer to cover the target surface, the coupling coefficient is enhanced by an order of magnitude. With the increase of the gap width between the target surface and the cover layer, the coupling coefficient exponentially decreases. It is found that the coupling coefficient is also related to the thickness of the cover layer.

Laser-induced microjet-assisted ablation for high-quality microfabrication

Liquid-assisted laser ablation has the advantage of relieving thermal effects of common laser ablation processes, whereas the light scattering and shielding effects by laser-induced cavitation bubbles, suspended debris, and turbulent liquid flow generally deteriorate laser beam transmission stability, leading to low energy efficiency and poor surface quality. Here, we report that a continuous and directional high-speed microjet will form in the laser ablation zone if laser-induced primary cavitation bubbles asymmetrically collapse sequentially near the air-liquid interface under a critical thin liquid layer. The laser-induced microjet can instantaneously and directionally remove secondary bubbles and ablation debris around the laser ablation region, and thus a very stable material removal process can be obtained. The shadowgraphs of high-speed camera reveal that the average speed of laser-induced continuous microjet can be as high as 1.1 m sin its initial 500 μm displacement. The coupling effect of laser ablation, mechanical impact along with the collapse of cavitation bubbles and flushing of high-speed microjet helps achieve a high material removal rate and significantly improved surface quality. We name this uncovered liquid-assisted laser ablation process as laser-induced microjet-assisted ablation(LIMJAA) based on its unique characteristics. High-quality microgrooves with a large depth-to-width ratio of 5.2 are obtained by LIMJAA with a single-pass laser scanning process in our experiments. LIMJAA is capable of machining various types of difficult-to-process materials with high-quality arrays of micro-channels, square and circle microscale through-holes. The results and disclosed mechanisms in our work provide a deep understanding of the role of laser-induced microjet in improving the processing quality of liquid-assisted laser micromachining.

A New Synthetical Model of High-Power Pulsed Laser Ablation

We develop a new synthetical model of high-power pulsed laser ablation,which considers the dynamicabsorptance,vaporization,and plasma shielding.And the corresponding heat conduction equations with the initial andboundary conditions are given.The numerical solutions are obtained under the reasonable technical parameter condi-tions by taking YBa_2Cu_3O_7 target for example.The space-dependence and time-dependence of temperature in targetat a certain laser fluence are presented,then,the transmitted intensity through plasma plume,space-dependence oftemperature and ablation rate for different laser fluences are significantly analyzed.As a result,the satisfactorily goodagreement between our numerical results and experimental results indicates that the influences of the dynamic absorp-tance,vaporization,and plasma shielding cannot be neglected.Taking all the three mechanisms above simultaneouslyinto account for the first time,we cause the present model to be more practical.

Hierarchical microstructures with high spatial frequency laser induced periodic surface structures possessing different orientations created by femtosecond laser ablation of silicon in liquids

High spatial frequency laser induced periodic surface structures(HSFLs)on silicon substrates are often developed on flat surfaces at low fluences near ablation threshold of 0.1 J/cm2,seldom on microstructures or microgrooves at relatively higher fluences above 1 J/cm^2.This work aims to enrich the variety of HSFLs-containing hierarchical microstructures,by femtosecond laser(pulse duration:457 fs,wavelength:1045 nm,and repetition rate:100 kHz)in liquids(water and acetone)at laser fluence of 1.7 J/cm^2.The period of Si-HSFLs in the range of 110–200 nm is independent of the scanning speeds(0.1,0.5,1 and 2 mm/s),line intervals(5,15 and 20μm)of scanning lines and scanning directions(perpendicular or parallel to light polarization direction).It is interestingly found that besides normal HSFLs whose orientations are perpendicular to the direction of light polarization,both clockwise or anticlockwise randomly tilted HSFLs with a maximal deviation angle of 50°as compared to those of normal HSFLSs are found on the microstructures with height gradients.Raman spectra and SEM characterization jointly clarify that surface melting and nanocapillary waves play important roles in the formation of Si-HSFLs.The fact that no HSFLs are produced by laser ablation in air indicates that moderate melting facilitated with ultrafast liquid cooling is beneficial for the formation of HSFLs by LALs.On the basis of our findings and previous reports,a synergistic formation mechanism for HSFLs at high fluence was proposed and discussed,including thermal melting with the concomitance of ultrafast cooling in liquids,transformation of the molten layers into ripples and nanotips by surface plasmon polaritons(SPP)and second-harmonic generation(SHG),and modulation of Si-HSFLs direction by both nanocapillary waves and the localized electric field coming from the excited large Si particles.

Focal ablation therapy presents promising results for selectively localized prostate cancer patients

Due to its lower risk of consequences when compared to a radical approach, focal treatment is a viable and minimally invasive option for treating specific localized prostate cancer. Although several recent good nonrandomized trials have suggested that focused therapy may be an alternative choice for some patients, additional high-quality evidence is needed before it can be made widely available as a conventional treatment. As a result, we have summarized the most recent findings from the 38th Annual European Association of Urology Congress, one of the most renowned annual conferences in the area of urology, regarding focal ablation therapy for patients with localized prostate cancer. Additionally, we also provided clinical trials in progress for researchers to better understand the current research status of this field.

Laser ablation in situ U-Pb dating and its application to diagenesis-porosity evolution of carbonate reservoirs

Through the development and calibration of a reference material which is 209.8 Ma old using a newly-developed Laser Ablation(LA)Multi-Collector Inductively Coupled Plasma Mass Spectrometry(MC-ICP-MS)technique,we successfully overcome the difficulty in sampling and dating ultra-low U-Pb ancient marine carbonates,which was previously untenable by isotope dilution(ID)methods.We developed the LA-MC-ICP-MS in situ U-Pb dating technique for ancient marine carbonates for the study of diagenesis-porosity evolution history in Sinian Dengying Formation,Sichuan Basin.By systematically dating of dolomitic cements from vugs,matrix pores and fractures,we found that the burial and diagenetic process of dolomite reservoirs in Sinian Dengying Formation was characterized by progressive filling-up of primary pores and epigenic dissolution vugs.The filling of vugs happened in three stages,early Caledonian,late Hercynian-Indosinian and Yanshanian-Himalayan,while the filling of matrix pores mainly took place in early Caledonian.The unfilled residual vugs,pores and fractures constitute the main reservoir sapce.Based on the above knowledge,we established the diagenesis-porosity evolution history of the dolomite reservoir in Sinian Dengying Formation,Sichuan Basin.These findings are highly consistent with the tectonic-burial and basin thermal histories of the study area.Our study confirmed the reliability of this in situ U-Pb dating technique,which provides an effective way for the investigation of diagenesis-porosity evolution history and evaluation of porosity in ancient marine carbonate reservoirs before hydrocarbon migration.

Time-resolved shadowgraphs and morphology analyses of aluminum ablation with multiple femtosecond laser pulses

Aluminum ablation by multiple femtosecond laser pulses is investigated via time-resolved shadowgraphs and scanning electron microscope （SEM） images of the ablation spot. The spatial distribution of the ejected material and the radius of the shock wave generated during the ablation are found to vary with the increase in the number of pulses. In the initial two pulses, nearly concentric and semicircular stripes within the shock wave front are observed, unlike in subsequent pulses. Ablation by multiple femtosecond pulses exhibits different characteristics compared with the case induced by single femtosecond pulse because of the changes to the aluminum target surface induced by the preceding pulses.

Liquid vortexes and flows induced by femtosecond laser ablation in liquid governing formation of circular and crisscross LIPSS

Orientations of laser induced periodic surface structures(LIPSS)are usually considered to be governed by the laser polarization state.In this work,we unveil that fluid dynamics induced by femtosecond(fs)laser ablation in liquid(fs-LAL)can easily break this polarization restriction to produce irregular circular-LIPSS(CLIPPS)and crisscross-LIPSS(CCLIPSS).Fs laser ablation of silicon in water shows formation of diverse LIPSS depending on ablation conditions.At a high power of 700 mW(repetition rate of 100 kHz,pulse duration of 457 fs and wavelength of 1045 nm),single/twin CLIPSS are produced at the bottom of macropores of several microns in diameter due to the formation of strong liquid vortexes and occurrence of the vortex shedding effect.Theoretical simulations validate our speculation about the formation of liquid vortex with an ultrahigh static pressure,which can induce the microstructure trenches and cracks at the sidewalls for fs-LAL of Si and tungsten(W)in water,respectively.At a low power of 50 mW,weak liquid vortexes are produced,which only give birth to curved LIPSS in the valleys of grooves.Consequently,it is deduced that liquid vortex plays a crucial role in the formation of macropores.Mountain-like microstructures induce complex fluid dynamics which can cause the formation of CCLIPSS on them.It is believed that liquid vortexes and fluid dynamics presented in this work open up new possibilities to diversify the morphologies of LIPSS formed by fs-LAL.

In-situ surface decoration of RuO_(2) nanoparticles by laser ablation for improved oxygen evolution reaction activity in both acid and alkali solutions

Improving the OER activity of noble metal-based materials is of profound importance to minimize the usage of noble metals and lower the cost.Here,we report considerable improvement on the catalytic activity of RuO_(2) particles for OER in both alkali and acid environments.The RuO_(2) nanoparticles were treated with a method of pulse laser ablation.Numerous Ru and RuO_(2) clusters were generated at the surface of RuO_(2) nanoparticles after the laser ablation,forming a lychee-shaped morphology.The larger pulse energy RuO_(2) nanoparticles are treated with,the better the OER activity can be.DFT calculations shows that the surface tension induced by the lychee-shaped morphology benefits the OER performance.Our best sample gives an overpotential of 172 mV(at 10 mA cm^(-2))and a Tafel slope of 53.5 mV dec^(-1) in KOH,while an overpotential of 219 mV and a Tafel slope of 44.9 mV dec^(-1) in H_(2)SO_(4),which are of topclass results.This work may inspire a new way to develop high-performance electrocatalysts for OER.

Disruption mitigation using laser ablation of high-Z impurities in HL-1M tokamak

A preliminary experiment triggering a plasma current quench by laser ablation of high-Z impurities has been performed in the HL-1M tokamak. The injection of impurities with higher electric charges into tokamak plasmas can increase the radiation cooling of the plasma. Resistive, highly radiating plasma formed prior to the thermal quench can dissipate both the thermal and magnetic energies, which is possibly a simple and potential approach to reducing significantly the plasma thermal energy and magnetic energy before a disruption thereby a safe plasma termination is obtained.

Microwave Ablation versus Laser Ablation in Occluding Lateral Veins in Goats

Increasing number of endovenous techniques are available for the treatment of saphenous vein reflux and endovenous laser ablation（EVLA） is a frequently used method. A newly developed alternative, based on thermal therapy, is endovenous microwave ablation（EMA）. This study evaluated the effect of the two procedures, in terms of coagulation and histological changes, in occluding lateral veins in goats. Twelve animals were randomized into two group, with 6 treated with EMA（EMA group）, and the rest 6 with EVLA（EVLA group）. Results of coagulation, including coagulation, fibrinolysis and platelet activation, were assessed at three or four different time points： before, immediately after, 24 h（and 48 h） after ablation. The diameter change, a measure of efficacy, was ultrasonographically measured before and 1 month after the ablation. Histological changes were grossly and microscopically evaluated immediately, 1 and 3 month（s） after the ablation. The length of the ablated vein and preoperative average diameter were comparable between the two groups. In both EMA and EVLA groups, several coagulation parameters, fibrinolysis and platelet activation parameters only underwent slight changes. Ultrasound imaging displayed that the diameter reduction of the veins treated by EMA was significantly larger than by EVLA, in consistent with the results of macroscopic examination. Microscopic examination revealed necrosis and thickening of the vein wall, and occlusion of the lumen within 3 months after ablation in both EMA and EVLA groups. It is concluded that EMA is a minimally invasive therapy, which appears to be safe and effective for treatment of lateral veins in goats.