A PVA-GAG-COL composite scaffold is fabricated by polyvinyl alcohol (PVA), glyeosaminoglycan (GAG) and collagen (COL). Laser surface modification technology is used to make holes on the surface of the scaffolds....A PVA-GAG-COL composite scaffold is fabricated by polyvinyl alcohol (PVA), glyeosaminoglycan (GAG) and collagen (COL). Laser surface modification technology is used to make holes on the surface of the scaffolds. Inside and outside interconnection micro-porous structure is obtained. Bioeompatibility test of the scaffolds shows that PVA-GAG-COL scaffold can promote the adhesion and proliferation of the fibroblast. Also, fibroblast can grow normally on the scaffolds with pore diameter from 115 um to 255 um and pore distance from 500 um to 2000 um. PVA-GAG-COL scaffolds possess excellent cell biocompatibility. The porous structure is suitable for cell culture in tissue engineering.展开更多
The present work explored effects of laser surface melting on microstructure and surface topography evolution in AZ31B magnesium alloy.Thermokinetic effects experienced by the material during laser surface melting wer...The present work explored effects of laser surface melting on microstructure and surface topography evolution in AZ31B magnesium alloy.Thermokinetic effects experienced by the material during laser surface melting were simulated using a multiphysics finite element model.Microstructure and phase evolution were examined using scanning electron microscopy,X-ray diffraction,and electron back scatter diffraction.Surface topography was evaluated using white light interferometry.The interaction of surface melted samples with simulated body fluid was monitored by contact angle measurements and immersion studies up to 7 days.Laser surface melting led to formation of a refined microstructure with predominantly basal crystallographic texture.Concurrently,the amount ofβphase(Mg_(17)Al_(12))increased with an increase in the laser fluence.βphase preferentially decorated the cell boundaries.In terms of topography,the surface became progressively rougher with an increase in laser fluence.As a result,upon immersion in simulated body fluid,the laser surface melted samples showed an improved wettability,corrosion resistance,and precipitation of mineral having composition closer to the hydroxyapatite bone mineral compared to the untreated sample.展开更多
Metal superhydrophobic surfaces with anisotropic wettability and adhesion have become more and more important due to their promising applications. Herein, we report a new fabrication strategy through a combination of ...Metal superhydrophobic surfaces with anisotropic wettability and adhesion have become more and more important due to their promising applications. Herein, we report a new fabrication strategy through a combination of pulsed laser ablation and low-temperature annealing post-processing. An inclined cone structure array is made on stainless steel surfaces, and then 120 °C low-temperature annealing is applied. Such surface displays excellent mechanical durability and anisotropic superhydrophobicity. It is demonstrated experimentally that the contact angle of water droplets on the surface is different along the parallel(167° ±2°) and perpendicular directions(157° ±2°) of the inclined cone structure. The sliding behaviors of water droplets and mechanical durability of the inclined cone structures are studied. These surfaces obtained in a short time with environmentally friendly fabrication can be applied in industries for water harvesting, droplet manipulation, and pipeline transportation.展开更多
Surface crack of components of the cast nickel base superalloy was repaired with twin laser beams under proper technological conditions. One laser beam was used to melt the substrate material of crack, and the other t...Surface crack of components of the cast nickel base superalloy was repaired with twin laser beams under proper technological conditions. One laser beam was used to melt the substrate material of crack, and the other to fill in powder material to the crack region. The experimental results show that the surface crack with the width of 0.1 ~ 0.3?mm could be repaired under the laser power of 3?kW and the scanning speed of 6 ~ 8?mm/s. The repaired deepness of crack region is below 6.5?mm. The microstructure of repaired region is the cellular crystal, columnar crystal dendrite crystal from the transition region to the top filled layer. The phases in repaired region mainly consisted of supersaturated α Co with plenty of Ni, some Cr and Al, Cr 23 C 6, Co 2B, Co Ni Mo, Ni 4B 3, TiSi and VSi. The hardness of filled layer in repaired region ranged from HV 0.2 450 to HV 0.2 500, and the hardness decreases gradually from the filled layer to joined zone.展开更多
Late in-stent thrombus and restenosis still represent two major challenges in stents’design.Surface treatment of stent is attracting attention due to the increasing importance of stenting intervention for coronary ar...Late in-stent thrombus and restenosis still represent two major challenges in stents’design.Surface treatment of stent is attracting attention due to the increasing importance of stenting intervention for coronary artery diseases.Several surface engineering techniques have been utilised to improve the biological response in vivo on a wide range of biomedical devices.As a tailorable,precise,and ultra-fast process,laser surface engineering offers the potential to treat stent materials and fabricate various 3D textures,including grooves,pillars,nanowires,porous and freeform structures,while also modifying surface chemistry through nitridation,oxidation and coatings.Laser-based processes can reduce the biodegradable materials’degradation rate,offering many advantages to improve stents’performance,such as increased endothelialisation rate,prohibition of SMC proliferation,reduced platelet adhesion and controlled corrosion and degradation.Nowadays,adequate research has been conducted on laser surface texturing and surface chemistry modification.Laser texturing on commercial stents has been also investigated and a promotion of performance of laser-textured stents has been proved.In this critical review,the influence of surface texture and surface chemistry on stents performance is firstly reviewed to understand the surface characteristics of stents required to facilitate cellular response.This is followed by the explicit illustration of laser surface engineering of stents and/or related materials.Laser induced periodic surface structure(LIPSS)on stent materials is then explored,and finally the application of laser surface modification techniques on latest generation of stent devices is highlighted to provide future trends and research direction on laser surface engineering of stents.展开更多
基金863 Program grant number: 2077AA09Z436+1 种基金Guangdong Province '211' Fund for Biomaterials and Tissue Engineering grantnumber: 50621030
文摘A PVA-GAG-COL composite scaffold is fabricated by polyvinyl alcohol (PVA), glyeosaminoglycan (GAG) and collagen (COL). Laser surface modification technology is used to make holes on the surface of the scaffolds. Inside and outside interconnection micro-porous structure is obtained. Bioeompatibility test of the scaffolds shows that PVA-GAG-COL scaffold can promote the adhesion and proliferation of the fibroblast. Also, fibroblast can grow normally on the scaffolds with pore diameter from 115 um to 255 um and pore distance from 500 um to 2000 um. PVA-GAG-COL scaffolds possess excellent cell biocompatibility. The porous structure is suitable for cell culture in tissue engineering.
文摘The present work explored effects of laser surface melting on microstructure and surface topography evolution in AZ31B magnesium alloy.Thermokinetic effects experienced by the material during laser surface melting were simulated using a multiphysics finite element model.Microstructure and phase evolution were examined using scanning electron microscopy,X-ray diffraction,and electron back scatter diffraction.Surface topography was evaluated using white light interferometry.The interaction of surface melted samples with simulated body fluid was monitored by contact angle measurements and immersion studies up to 7 days.Laser surface melting led to formation of a refined microstructure with predominantly basal crystallographic texture.Concurrently,the amount ofβphase(Mg_(17)Al_(12))increased with an increase in the laser fluence.βphase preferentially decorated the cell boundaries.In terms of topography,the surface became progressively rougher with an increase in laser fluence.As a result,upon immersion in simulated body fluid,the laser surface melted samples showed an improved wettability,corrosion resistance,and precipitation of mineral having composition closer to the hydroxyapatite bone mineral compared to the untreated sample.
基金Project(A19C2a0019) supported by the Advanced Remanufacturing and Technology Centre (ARTC) under its RIE2020 Advanced Manufacturing and Engineering (AME) IAF PP,Singapore。
文摘Metal superhydrophobic surfaces with anisotropic wettability and adhesion have become more and more important due to their promising applications. Herein, we report a new fabrication strategy through a combination of pulsed laser ablation and low-temperature annealing post-processing. An inclined cone structure array is made on stainless steel surfaces, and then 120 °C low-temperature annealing is applied. Such surface displays excellent mechanical durability and anisotropic superhydrophobicity. It is demonstrated experimentally that the contact angle of water droplets on the surface is different along the parallel(167° ±2°) and perpendicular directions(157° ±2°) of the inclined cone structure. The sliding behaviors of water droplets and mechanical durability of the inclined cone structures are studied. These surfaces obtained in a short time with environmentally friendly fabrication can be applied in industries for water harvesting, droplet manipulation, and pipeline transportation.
文摘Surface crack of components of the cast nickel base superalloy was repaired with twin laser beams under proper technological conditions. One laser beam was used to melt the substrate material of crack, and the other to fill in powder material to the crack region. The experimental results show that the surface crack with the width of 0.1 ~ 0.3?mm could be repaired under the laser power of 3?kW and the scanning speed of 6 ~ 8?mm/s. The repaired deepness of crack region is below 6.5?mm. The microstructure of repaired region is the cellular crystal, columnar crystal dendrite crystal from the transition region to the top filled layer. The phases in repaired region mainly consisted of supersaturated α Co with plenty of Ni, some Cr and Al, Cr 23 C 6, Co 2B, Co Ni Mo, Ni 4B 3, TiSi and VSi. The hardness of filled layer in repaired region ranged from HV 0.2 450 to HV 0.2 500, and the hardness decreases gradually from the filled layer to joined zone.
文摘Late in-stent thrombus and restenosis still represent two major challenges in stents’design.Surface treatment of stent is attracting attention due to the increasing importance of stenting intervention for coronary artery diseases.Several surface engineering techniques have been utilised to improve the biological response in vivo on a wide range of biomedical devices.As a tailorable,precise,and ultra-fast process,laser surface engineering offers the potential to treat stent materials and fabricate various 3D textures,including grooves,pillars,nanowires,porous and freeform structures,while also modifying surface chemistry through nitridation,oxidation and coatings.Laser-based processes can reduce the biodegradable materials’degradation rate,offering many advantages to improve stents’performance,such as increased endothelialisation rate,prohibition of SMC proliferation,reduced platelet adhesion and controlled corrosion and degradation.Nowadays,adequate research has been conducted on laser surface texturing and surface chemistry modification.Laser texturing on commercial stents has been also investigated and a promotion of performance of laser-textured stents has been proved.In this critical review,the influence of surface texture and surface chemistry on stents performance is firstly reviewed to understand the surface characteristics of stents required to facilitate cellular response.This is followed by the explicit illustration of laser surface engineering of stents and/or related materials.Laser induced periodic surface structure(LIPSS)on stent materials is then explored,and finally the application of laser surface modification techniques on latest generation of stent devices is highlighted to provide future trends and research direction on laser surface engineering of stents.