The Late Quaternary slip rate along the Maqu segment of the eastern Kunlun Fault was estimated using a combination of high-resolution remote sensing imagery interpretation, field observations and differential Global P...The Late Quaternary slip rate along the Maqu segment of the eastern Kunlun Fault was estimated using a combination of high-resolution remote sensing imagery interpretation, field observations and differential Global Positioning System（GPS） measurements of offset river terraces, and 14 C dating of snail shells collected from offset risers. The results show that the left-slip rate along the segment is 3–5 mm/a, and that the vertical slip rate is 0.3–0.5 mm/a. Both the horizontal and vertical slips on the segment remain consistent over a distance of ~100 km. It means that no slip gradient as previously suggested occurred along the Maqu segment, and which thus might behave as an independent seismogenic fault. Judging from multiple relationships among young terrace offsets, we infer that co-seismic surface rupture produced by a characteristic earthquake with a magnitude of Ms7.0–7.5 on the Maqu fault could generate a horizontal slip of 4.5–5 m and a vertical slip of 0.45–0.5 m, with a corresponding ratio（Dh/Dv） of about 9. Two surface rupture events must have occurred over the past 3300 years, the latest one possibly between 1485 cal BP and 1730 cal BP.展开更多
On the basis of accelerator mass spectrometer radiocarbon （AMS ^14C） dating, sedimentation rates of 11 cores collected from the northern to southern Okinawa Trough are discussed. The sedimentation rates in the Okina...On the basis of accelerator mass spectrometer radiocarbon （AMS ^14C） dating, sedimentation rates of 11 cores collected from the northern to southern Okinawa Trough are discussed. The sedimentation rates in the Okinawa Trough roughly range from 11 to 39cm/ka, and the average is 23.0cm/ka. China＇s continental matter is the main sediment source of the middle Okinawa Trough and has important contribution to the northern and southern Okinawa Trough. The sedimentation rates during the marine oxygen isotope （MIS） 2 are uniformly higher than those during MIS 1 in the northern and middle Okinawa Trough while they are on the contrary in the southern Okinawa Trough. Sedimentation rates in the Okinawa Trough can be one of the proxies of sediment source and an indicator of cooling events.展开更多
The I ingwu fault is in the eastern boundary of the southern section of Yinchuan graben. It hasa close relation to seismicity in the Lingwu-Wuzhong region.Few researches have been done.In this Paper,on the basis of te...The I ingwu fault is in the eastern boundary of the southern section of Yinchuan graben. It hasa close relation to seismicity in the Lingwu-Wuzhong region.Few researches have been done.In this Paper,on the basis of tee data obtained from field investigation,the activity features inLate Quaternary have been discussed.The vertical displacement and its slip rate have been alsoestimated.The fault is 48km in length,being divided into 3 segments according to geologicaland topographical characteristics.The last rupture along its northern and middle segments wasoccurred in late of Late Pleistocene or early Holocene while that along the southern segmentwas occurred in midle Holocene.The vertical slip rate is estimated as 0.23～025mm/a sinceabout 66ka B.P.based on the vertical displacements of terracesⅠ,Ⅱ and Ⅲ and their ages.展开更多
New clinical approaches are imperative beyond the widely adopted National Comprehensive Cancer Network (NCCN) guidelines, utilized by prominent cancer institutions. Cancer is the leading cause of death among individua...New clinical approaches are imperative beyond the widely adopted National Comprehensive Cancer Network (NCCN) guidelines, utilized by prominent cancer institutions. Cancer is the leading cause of death among individuals younger than 85 years within the United States. Despite significant technological advances, including the expenditure of hundreds of billions, treatment outcomes and overall survival have not notably improved for most types of advanced cancer over the last several decades. Over the past 24 years, Envita Medical Centers has pioneered a unique form of personalized treatment approach for late-stage and refractory cancer patients, introducing groundbreaking innovations in the field. Our integrated algorithm utilizes advanced genomics, transcriptomics, and highly tailored immunotherapy, resulting in remarkable outcome improvements. This study presents Envita’s innovative personalized treatment algorithms and examines the response outcomes of 199 late-stage cancer patients treated at Envita Medical Centers over a two-year period. Compared to standard of care and palliative chemotherapy, Envita’s treatment demonstrated a remarkable 35-fold improvement in overall response rates (Figure 1). Moreover, 88% of the patients, the majority presenting with Stage 3 or 4 cancer, experienced a 43-fold improvement in quality of life with minimal side effects, as compared to standard of care chemotherapy and palliative care. This revolutionary success is attributed to Envita’s personalized therapeutic algorithms, which incorporate customized immunotherapy. Envita’s precision care approach has also achieved a 100% better response rate compared to over 65 global chemotherapy clinical trials with more than 2700 patients. The results from this study suggest that a wider utilization of Envita’s personalized approach can significantly benefit patients with late-stage and refractory cancer.展开更多
Phurejas potatoes (Solanum phureja Juz et Buk) are cultivated in very restricted areas of the Bolivian Andes. Late blight caused by Phytophthora infestans is a destructive, endemic disease that affects the survival an...Phurejas potatoes (Solanum phureja Juz et Buk) are cultivated in very restricted areas of the Bolivian Andes. Late blight caused by Phytophthora infestans is a destructive, endemic disease that affects the survival and cultivation of this crop. The aim of this study was to determine the resistance characteristics of phurejas potato varieties to P. infestans in a traditional area of cultivation. An experimental plot was prepared in the locality of Chojchoni (3200 m) and planted with different phurejas varieties: 1) Chojllu Phureja (Sste);2) Phureja Amarilla (Sphu);3) Polo Phureja (Sphu);4) Phureja Roja (Sphu);5) Phureja Negra (Sphu) and 6) Waych’a Pacena (Sadg), a susceptible control. Severity was assessed according to the criteria of the Centro Internacional dela Papa, determining the area under the disease progress curve (AUDPC). Regression analysis (logN disease severity against time) was performed using the logistic model [ln(y/1 - y)] to determine infection rates. The different varieties showed different levels of resistance. The disease progress curve, the AUDPC and the linear regression results revealed the varieties Chojllu Phureja, Phureja Amarilla and Polo Phureja to likely have larger copy numbers of minor resistance genes against P. infestans than Phureja Roja or Phureja Negra. Late blight caused by P. infestans could cause the long-term loss of some phurejas varieties through farmers selecting others less severely affected by the disease.展开更多
为解决长江流域稻油茬口矛盾,提高冬闲田利用率,亟须迟播油菜(10月25日之后播种)配套技术研究。本研究以早熟品种‘华油杂137’为材料,在湖北武汉进行2年播种期(10月25日至11月15日间,各播种期间隔3 d,用S1~S8表示)和播种量(2.5、5.0、...为解决长江流域稻油茬口矛盾,提高冬闲田利用率,亟须迟播油菜(10月25日之后播种)配套技术研究。本研究以早熟品种‘华油杂137’为材料,在湖北武汉进行2年播种期(10月25日至11月15日间,各播种期间隔3 d,用S1~S8表示)和播种量(2.5、5.0、7.5、10.0和12.5 kg hm^(-2),用R1~R5表示)单因素试验,考察生育期、成苗动态、农艺性状、产量和倒伏指标,统计有效积温,通过线性回归和平滑曲线拟合分析,优化播种期和播种量的配置参数,为迟播油菜生产提供技术支撑。结果表明,(1)播种期推迟,迟播油菜的生育期缩短、根颈粗降低、分枝数减少、产量降低且茎秆倒伏指数增加;4个生育期中,苗期和花期有效积温与产量呈极显著正相关。(2)播种量增加,各生育期成苗数和收获密度提高,但生育期缩短、有效积温减少,角果层厚度降低、倒伏指数先降后增、产量呈先增后降趋势。(3)2年不同播种期产量数据回归分析表明,播种期推迟至S3~S4时,越冬前有效积温保持在317.1℃以上,苗期有效积温达401.1℃,终花35 d收获产量可达2700.0 kg hm^(-2),倒伏指数为1.5左右;2年不同播种量产量数据平滑曲线拟合分析表明,不同播种量下收获密度与产量呈抛物线关系,收获密度为64.2×10^(4)株hm^(-2)时终花35 d收获产量达峰值,为2948.5 kg hm^(-2),而倒伏指数为1.6。综上,配置7.5~10.0 kg hm^(-2)的播种量确保收获密度达64.2×10^(4)株hm^(-2),抢时播种确保冬前有效积温达317.1℃,可显著提高迟播油菜产量与抗倒性。展开更多
祁连山东段发育了多条大型活动断裂,如近东西向展布的天桥沟-黄羊川断裂及北西西向展布的金强河断裂、毛毛山断裂、老虎山断裂等,在马雅雪山北麓、宝泉山隆起北缘还发育了一条整体呈北西-北西西向展布的马雅雪山断裂。其中,前人已对天桥...祁连山东段发育了多条大型活动断裂,如近东西向展布的天桥沟-黄羊川断裂及北西西向展布的金强河断裂、毛毛山断裂、老虎山断裂等,在马雅雪山北麓、宝泉山隆起北缘还发育了一条整体呈北西-北西西向展布的马雅雪山断裂。其中,前人已对天桥沟-黄羊川断裂、金强河断裂、毛毛山断裂、老虎山断裂的晚第四纪活动开展了大量的研究,相比而言,马雅雪山断裂的研究程度还较低,其最新构造活动特征及其与区域主干活动断裂之间的关系等尚不清楚。马雅雪山断裂构成了天祝盆地与南部山体、丘陵的分界线,迹线清晰,断层三角面、断层槽谷多见,局部冲洪积阶地可见线性展布的断层陡坎,显示出断裂在晚第四纪有一定的活动。本研究对马雅雪山断裂西部的金强河段开展了实地调查,重点对马营沟及小黑刺沟2处的阶地断层陡坎开展了高精度地形地貌测量及阶地地貌面定年,对滑动速率进行了厘定。研究结果表明,马雅雪山断裂金强河段晚第四纪活动显著,断裂最近强震活动发生在8.21~3.43 ka BP,晚更新世晚期以来的垂直滑动速率为0.45~0.63 mm/a。展开更多
目的:探讨水囊引产与米索前列醇引产对足月妊娠孕妇的影响。方法:选取2022年1月—2023年6月厦门莲花医院收治的100例足月妊娠孕妇。根据随机数表法将其分为对照组和观察组,各50例。对照组采用米索前列醇引产,观察组采用水囊引产。比较...目的:探讨水囊引产与米索前列醇引产对足月妊娠孕妇的影响。方法:选取2022年1月—2023年6月厦门莲花医院收治的100例足月妊娠孕妇。根据随机数表法将其分为对照组和观察组,各50例。对照组采用米索前列醇引产,观察组采用水囊引产。比较两组促宫颈成熟效果、相关指标、分娩产程、分娩方式、并发症及满意度。结果:观察组促宫颈成熟总有效率高于对照组,差异有统计学意义(P<0.05)。观察组临产时间早于对照组,产后24 h出血量少于对照组,新生儿5 min Apgar评分高于对照组,差异有统计学意义(P<0.05)。观察组阴道分娩率高于对照组,第一产程、第二产程、第三产程均短于对照组,差异有统计学意义(P<0.05)。两组并发症发生率比较,差异无统计学意义(P>0.05)。观察组总满意度高于对照组,差异有统计学意义(P<0.05)。结论:水囊引产较米索前列醇引产更利于宫颈成熟,可缩短产程,降低剖宫产率,提高孕妇满意度。展开更多
基金support of the Natural Science Foundation of China(41472178)the China Geological Survey projects(1212011120167,12120114002211)
文摘The Late Quaternary slip rate along the Maqu segment of the eastern Kunlun Fault was estimated using a combination of high-resolution remote sensing imagery interpretation, field observations and differential Global Positioning System（GPS） measurements of offset river terraces, and 14 C dating of snail shells collected from offset risers. The results show that the left-slip rate along the segment is 3–5 mm/a, and that the vertical slip rate is 0.3–0.5 mm/a. Both the horizontal and vertical slips on the segment remain consistent over a distance of ~100 km. It means that no slip gradient as previously suggested occurred along the Maqu segment, and which thus might behave as an independent seismogenic fault. Judging from multiple relationships among young terrace offsets, we infer that co-seismic surface rupture produced by a characteristic earthquake with a magnitude of Ms7.0–7.5 on the Maqu fault could generate a horizontal slip of 4.5–5 m and a vertical slip of 0.45–0.5 m, with a corresponding ratio（Dh/Dv） of about 9. Two surface rupture events must have occurred over the past 3300 years, the latest one possibly between 1485 cal BP and 1730 cal BP.
基金This study was supported by the National Natural Science Foundation of China under contract Nos 40176018,40421150011 and 49776292the Ministry of Science and Technology,State Oceanic Administration,China,and IFR EMER,France.
文摘On the basis of accelerator mass spectrometer radiocarbon （AMS ^14C） dating, sedimentation rates of 11 cores collected from the northern to southern Okinawa Trough are discussed. The sedimentation rates in the Okinawa Trough roughly range from 11 to 39cm/ka, and the average is 23.0cm/ka. China＇s continental matter is the main sediment source of the middle Okinawa Trough and has important contribution to the northern and southern Okinawa Trough. The sedimentation rates during the marine oxygen isotope （MIS） 2 are uniformly higher than those during MIS 1 in the northern and middle Okinawa Trough while they are on the contrary in the southern Okinawa Trough. Sedimentation rates in the Okinawa Trough can be one of the proxies of sediment source and an indicator of cooling events.
基金This project was sponsored by the Joint Earthquake Seience Foundation (197013) and the Commission of Science and Technology, Ningxia Hui Autonomous Region, China.
文摘The I ingwu fault is in the eastern boundary of the southern section of Yinchuan graben. It hasa close relation to seismicity in the Lingwu-Wuzhong region.Few researches have been done.In this Paper,on the basis of tee data obtained from field investigation,the activity features inLate Quaternary have been discussed.The vertical displacement and its slip rate have been alsoestimated.The fault is 48km in length,being divided into 3 segments according to geologicaland topographical characteristics.The last rupture along its northern and middle segments wasoccurred in late of Late Pleistocene or early Holocene while that along the southern segmentwas occurred in midle Holocene.The vertical slip rate is estimated as 0.23～025mm/a sinceabout 66ka B.P.based on the vertical displacements of terracesⅠ,Ⅱ and Ⅲ and their ages.
文摘New clinical approaches are imperative beyond the widely adopted National Comprehensive Cancer Network (NCCN) guidelines, utilized by prominent cancer institutions. Cancer is the leading cause of death among individuals younger than 85 years within the United States. Despite significant technological advances, including the expenditure of hundreds of billions, treatment outcomes and overall survival have not notably improved for most types of advanced cancer over the last several decades. Over the past 24 years, Envita Medical Centers has pioneered a unique form of personalized treatment approach for late-stage and refractory cancer patients, introducing groundbreaking innovations in the field. Our integrated algorithm utilizes advanced genomics, transcriptomics, and highly tailored immunotherapy, resulting in remarkable outcome improvements. This study presents Envita’s innovative personalized treatment algorithms and examines the response outcomes of 199 late-stage cancer patients treated at Envita Medical Centers over a two-year period. Compared to standard of care and palliative chemotherapy, Envita’s treatment demonstrated a remarkable 35-fold improvement in overall response rates (Figure 1). Moreover, 88% of the patients, the majority presenting with Stage 3 or 4 cancer, experienced a 43-fold improvement in quality of life with minimal side effects, as compared to standard of care chemotherapy and palliative care. This revolutionary success is attributed to Envita’s personalized therapeutic algorithms, which incorporate customized immunotherapy. Envita’s precision care approach has also achieved a 100% better response rate compared to over 65 global chemotherapy clinical trials with more than 2700 patients. The results from this study suggest that a wider utilization of Envita’s personalized approach can significantly benefit patients with late-stage and refractory cancer.
文摘Phurejas potatoes (Solanum phureja Juz et Buk) are cultivated in very restricted areas of the Bolivian Andes. Late blight caused by Phytophthora infestans is a destructive, endemic disease that affects the survival and cultivation of this crop. The aim of this study was to determine the resistance characteristics of phurejas potato varieties to P. infestans in a traditional area of cultivation. An experimental plot was prepared in the locality of Chojchoni (3200 m) and planted with different phurejas varieties: 1) Chojllu Phureja (Sste);2) Phureja Amarilla (Sphu);3) Polo Phureja (Sphu);4) Phureja Roja (Sphu);5) Phureja Negra (Sphu) and 6) Waych’a Pacena (Sadg), a susceptible control. Severity was assessed according to the criteria of the Centro Internacional dela Papa, determining the area under the disease progress curve (AUDPC). Regression analysis (logN disease severity against time) was performed using the logistic model [ln(y/1 - y)] to determine infection rates. The different varieties showed different levels of resistance. The disease progress curve, the AUDPC and the linear regression results revealed the varieties Chojllu Phureja, Phureja Amarilla and Polo Phureja to likely have larger copy numbers of minor resistance genes against P. infestans than Phureja Roja or Phureja Negra. Late blight caused by P. infestans could cause the long-term loss of some phurejas varieties through farmers selecting others less severely affected by the disease.
文摘为解决长江流域稻油茬口矛盾,提高冬闲田利用率,亟须迟播油菜(10月25日之后播种)配套技术研究。本研究以早熟品种‘华油杂137’为材料,在湖北武汉进行2年播种期(10月25日至11月15日间,各播种期间隔3 d,用S1~S8表示)和播种量(2.5、5.0、7.5、10.0和12.5 kg hm^(-2),用R1~R5表示)单因素试验,考察生育期、成苗动态、农艺性状、产量和倒伏指标,统计有效积温,通过线性回归和平滑曲线拟合分析,优化播种期和播种量的配置参数,为迟播油菜生产提供技术支撑。结果表明,(1)播种期推迟,迟播油菜的生育期缩短、根颈粗降低、分枝数减少、产量降低且茎秆倒伏指数增加;4个生育期中,苗期和花期有效积温与产量呈极显著正相关。(2)播种量增加,各生育期成苗数和收获密度提高,但生育期缩短、有效积温减少,角果层厚度降低、倒伏指数先降后增、产量呈先增后降趋势。(3)2年不同播种期产量数据回归分析表明,播种期推迟至S3~S4时,越冬前有效积温保持在317.1℃以上,苗期有效积温达401.1℃,终花35 d收获产量可达2700.0 kg hm^(-2),倒伏指数为1.5左右;2年不同播种量产量数据平滑曲线拟合分析表明,不同播种量下收获密度与产量呈抛物线关系,收获密度为64.2×10^(4)株hm^(-2)时终花35 d收获产量达峰值,为2948.5 kg hm^(-2),而倒伏指数为1.6。综上,配置7.5~10.0 kg hm^(-2)的播种量确保收获密度达64.2×10^(4)株hm^(-2),抢时播种确保冬前有效积温达317.1℃,可显著提高迟播油菜产量与抗倒性。
文摘祁连山东段发育了多条大型活动断裂,如近东西向展布的天桥沟-黄羊川断裂及北西西向展布的金强河断裂、毛毛山断裂、老虎山断裂等,在马雅雪山北麓、宝泉山隆起北缘还发育了一条整体呈北西-北西西向展布的马雅雪山断裂。其中,前人已对天桥沟-黄羊川断裂、金强河断裂、毛毛山断裂、老虎山断裂的晚第四纪活动开展了大量的研究,相比而言,马雅雪山断裂的研究程度还较低,其最新构造活动特征及其与区域主干活动断裂之间的关系等尚不清楚。马雅雪山断裂构成了天祝盆地与南部山体、丘陵的分界线,迹线清晰,断层三角面、断层槽谷多见,局部冲洪积阶地可见线性展布的断层陡坎,显示出断裂在晚第四纪有一定的活动。本研究对马雅雪山断裂西部的金强河段开展了实地调查,重点对马营沟及小黑刺沟2处的阶地断层陡坎开展了高精度地形地貌测量及阶地地貌面定年,对滑动速率进行了厘定。研究结果表明,马雅雪山断裂金强河段晚第四纪活动显著,断裂最近强震活动发生在8.21~3.43 ka BP,晚更新世晚期以来的垂直滑动速率为0.45~0.63 mm/a。
文摘目的:探讨水囊引产与米索前列醇引产对足月妊娠孕妇的影响。方法:选取2022年1月—2023年6月厦门莲花医院收治的100例足月妊娠孕妇。根据随机数表法将其分为对照组和观察组,各50例。对照组采用米索前列醇引产,观察组采用水囊引产。比较两组促宫颈成熟效果、相关指标、分娩产程、分娩方式、并发症及满意度。结果:观察组促宫颈成熟总有效率高于对照组,差异有统计学意义(P<0.05)。观察组临产时间早于对照组,产后24 h出血量少于对照组,新生儿5 min Apgar评分高于对照组,差异有统计学意义(P<0.05)。观察组阴道分娩率高于对照组,第一产程、第二产程、第三产程均短于对照组,差异有统计学意义(P<0.05)。两组并发症发生率比较,差异无统计学意义(P>0.05)。观察组总满意度高于对照组,差异有统计学意义(P<0.05)。结论:水囊引产较米索前列醇引产更利于宫颈成熟,可缩短产程,降低剖宫产率,提高孕妇满意度。
