Breast cancer(BC) in men represents between 0.5% and 1% of all BC diagnosed each year. We report a case of advanced BC in a 62-year-old male treated at our interdisciplinary Breast Cancer Center. The patient presented...Breast cancer(BC) in men represents between 0.5% and 1% of all BC diagnosed each year. We report a case of advanced BC in a 62-year-old male treated at our interdisciplinary Breast Cancer Center. The patient presented with a newly diagnosed large, symptomatic mass in his left breast. Clinical examination showed a not movable mass of 16 cm diameter, deforming the whole breast; the overlying skin was livid and hypervascularized. Enlarged lymph nodes were palpable in the axillary pit. He had no concomitant diseases at time of presentation. He denied any first- or second degree family medical history of cancer of any type and he never received radiotherapy. Ultrasound guided minimal-invasive 14-gauge core biopsy revealed a moderately differentiated encapsulated papillary carcinoma with high expression of estrogen and progesterone receptors(both > 80%, IRS 12) and HER2-negative. Because of the tumor size a mastectomy with axillary dissection and chest wall reconstruction using a latissimus dorsi flap was performed. Histological analysis showed invasive growth besides typical(non-invasive) papillary carcinoma and was classified as invasive solid papillary carcinoma; p T3(10 cm), p N0(0/15), M0,R0; Oncotype DX Recurrence Score indicated low risk(RS: 2). After discussion in the interdisciplinary tumor board meeting, radiation therapy and tamoxifen were recommended. The patient had an uneventful recovery and is disease-free after two years of follow-up. Male BC is typically diagnosed at an advanced stage, most likely due to a lack of awareness that men can develop BC. Therefore, in case of a large tumor, a flap-based thoracic reconstruction may be required.展开更多
Background： The latissimus dorsi （LD） flap procedure remains a popular and useful breast reconstrtlction tool in China and Western countries, and donor site seroma formation is the main complication. This study was...Background： The latissimus dorsi （LD） flap procedure remains a popular and useful breast reconstrtlction tool in China and Western countries, and donor site seroma formation is the main complication. This study was conducted in Chinese patients to determine whether stable cases of seromas would resolve without treatment. Methods： A retrospective review of 45 consecutive cases of immediate breast reconstruction with LD flap from April 2012 to February 2017 was conducted. The scope of the seroma was demarcated with a marker pen, and cases that remained stable over time （i.e. the size of the seroma did not increase） were observed without treatment. The measured outcomes included the incidence ofseromas, the volume and duration of postoperative wound drainage, and other demographic characteristics. Results： Twenty-four patients （53.3%） developed a seroma at the donor site. Of these, 21 patients （87.5%） did not require treatment, and the seroma resolved over time. The mean duration of a sustained serol-na was 6.8 ± 1.4 weeks （range： 4-9 weeks）. Conclusions： This study observed the scope and progression of the seromas and found that seromas at the LD donor sites resolved over time without treatnlent.展开更多
Aim:Permanent expanders allow for breast reconstruction as a single stage.These prostheses are more expensive than conventional tissue expanders,but this excess cost is markedly offset as only one operation is require...Aim:Permanent expanders allow for breast reconstruction as a single stage.These prostheses are more expensive than conventional tissue expanders,but this excess cost is markedly offset as only one operation is required.However,if the revision rate is sufficiently high,then this effect is negated.We aim to compare costs of one-stage vs.two-stage reconstruction at a single center,taking into account explantation and unexpected admissions following complications.Methods:A retrospective review was carried out on all patients who underwent one-stage and two-stage reconstruction over a 5-year period by a single surgeon.A cost analysis was performed taking into account,explantation and additional admissions.Results:One hundred and forty-three one-stage and 45 two-stage procedures were included.The explantation rate for one-stage procedures is 36%,at a mean of 12.9 months postimplantation,the majority of which were exchanged for silicone implants to improve cosmesis.Four(9%)of the two-stage procedures were explanted a mean of 18 months postreconstruction.Overall,one-stage reconstructions were significantly more expensive than the two-stage group(P=0.016).Conclusion:There are many benefits of one-stage breast reconstruction.However,it does not appear to be cost-effective when additional admissions for explantation surgery are taken into account.展开更多
目的探讨三维可视技术在腔镜乳腺癌保乳并一期转移背阔肌瓣乳房重建中的指导价值。方法 2015年1月~2016年5月期间,我院临床30例志愿要求行背阔肌瓣转移重建乳房的患者纳入实验组,术前采集256排螺旋CT动脉期、静脉期的DICOM数据,导入自...目的探讨三维可视技术在腔镜乳腺癌保乳并一期转移背阔肌瓣乳房重建中的指导价值。方法 2015年1月~2016年5月期间,我院临床30例志愿要求行背阔肌瓣转移重建乳房的患者纳入实验组,术前采集256排螺旋CT动脉期、静脉期的DICOM数据,导入自主研发的医学图像三维可视化系统对患者CTA图像中的乳房、乳腺肿瘤、背阔肌及胸背动脉等进行分割及三维重建,再导入三维可视化手术平台中进行手术研究,指导临床腔镜乳腺癌保乳并一期转移背阔肌瓣乳房重建手术方案的制定和实施。术后6个月随访患者,进行美学评价。对照2014年1月~2014年12月期间18例在我院行腔镜背阔肌瓣乳房重建患者(术前未应用三维可视技术)的手术时间、术中出血量、术后6月乳房的美学评价等数据。结果实验组30例患者,三维可视技术能准确反映其乳房及肿瘤、背阔肌及胸背血管等解剖结构及其三维毗邻关系。30例患者手术顺利,中位手术时间为226 min(205~253 min),术中中位出血量为95 m L(73~132 m L)。乳房美学评价,22例优,6例良,2例一般。对照组18例患者,中位手术时间为283 min(256~313 min),中位出血量为107 m L(79~147 m L)。乳房美学评价,10例优,4例良,4例一般。结论三维可视技术能很好的显示背阔肌形态及胸背动脉走行,可计算乳房体积及背阔肌体积,指导背阔肌切取范围,避免误伤背阔肌瓣蒂部血管,缩短手术时间,减少术中出血,术后乳房重建效果良好。展开更多
文摘Breast cancer(BC) in men represents between 0.5% and 1% of all BC diagnosed each year. We report a case of advanced BC in a 62-year-old male treated at our interdisciplinary Breast Cancer Center. The patient presented with a newly diagnosed large, symptomatic mass in his left breast. Clinical examination showed a not movable mass of 16 cm diameter, deforming the whole breast; the overlying skin was livid and hypervascularized. Enlarged lymph nodes were palpable in the axillary pit. He had no concomitant diseases at time of presentation. He denied any first- or second degree family medical history of cancer of any type and he never received radiotherapy. Ultrasound guided minimal-invasive 14-gauge core biopsy revealed a moderately differentiated encapsulated papillary carcinoma with high expression of estrogen and progesterone receptors(both > 80%, IRS 12) and HER2-negative. Because of the tumor size a mastectomy with axillary dissection and chest wall reconstruction using a latissimus dorsi flap was performed. Histological analysis showed invasive growth besides typical(non-invasive) papillary carcinoma and was classified as invasive solid papillary carcinoma; p T3(10 cm), p N0(0/15), M0,R0; Oncotype DX Recurrence Score indicated low risk(RS: 2). After discussion in the interdisciplinary tumor board meeting, radiation therapy and tamoxifen were recommended. The patient had an uneventful recovery and is disease-free after two years of follow-up. Male BC is typically diagnosed at an advanced stage, most likely due to a lack of awareness that men can develop BC. Therefore, in case of a large tumor, a flap-based thoracic reconstruction may be required.
文摘Background： The latissimus dorsi （LD） flap procedure remains a popular and useful breast reconstrtlction tool in China and Western countries, and donor site seroma formation is the main complication. This study was conducted in Chinese patients to determine whether stable cases of seromas would resolve without treatment. Methods： A retrospective review of 45 consecutive cases of immediate breast reconstruction with LD flap from April 2012 to February 2017 was conducted. The scope of the seroma was demarcated with a marker pen, and cases that remained stable over time （i.e. the size of the seroma did not increase） were observed without treatment. The measured outcomes included the incidence ofseromas, the volume and duration of postoperative wound drainage, and other demographic characteristics. Results： Twenty-four patients （53.3%） developed a seroma at the donor site. Of these, 21 patients （87.5%） did not require treatment, and the seroma resolved over time. The mean duration of a sustained serol-na was 6.8 ± 1.4 weeks （range： 4-9 weeks）. Conclusions： This study observed the scope and progression of the seromas and found that seromas at the LD donor sites resolved over time without treatnlent.
文摘Aim:Permanent expanders allow for breast reconstruction as a single stage.These prostheses are more expensive than conventional tissue expanders,but this excess cost is markedly offset as only one operation is required.However,if the revision rate is sufficiently high,then this effect is negated.We aim to compare costs of one-stage vs.two-stage reconstruction at a single center,taking into account explantation and unexpected admissions following complications.Methods:A retrospective review was carried out on all patients who underwent one-stage and two-stage reconstruction over a 5-year period by a single surgeon.A cost analysis was performed taking into account,explantation and additional admissions.Results:One hundred and forty-three one-stage and 45 two-stage procedures were included.The explantation rate for one-stage procedures is 36%,at a mean of 12.9 months postimplantation,the majority of which were exchanged for silicone implants to improve cosmesis.Four(9%)of the two-stage procedures were explanted a mean of 18 months postreconstruction.Overall,one-stage reconstructions were significantly more expensive than the two-stage group(P=0.016).Conclusion:There are many benefits of one-stage breast reconstruction.However,it does not appear to be cost-effective when additional admissions for explantation surgery are taken into account.
文摘目的探讨三维可视技术在腔镜乳腺癌保乳并一期转移背阔肌瓣乳房重建中的指导价值。方法 2015年1月~2016年5月期间,我院临床30例志愿要求行背阔肌瓣转移重建乳房的患者纳入实验组,术前采集256排螺旋CT动脉期、静脉期的DICOM数据,导入自主研发的医学图像三维可视化系统对患者CTA图像中的乳房、乳腺肿瘤、背阔肌及胸背动脉等进行分割及三维重建,再导入三维可视化手术平台中进行手术研究,指导临床腔镜乳腺癌保乳并一期转移背阔肌瓣乳房重建手术方案的制定和实施。术后6个月随访患者,进行美学评价。对照2014年1月~2014年12月期间18例在我院行腔镜背阔肌瓣乳房重建患者(术前未应用三维可视技术)的手术时间、术中出血量、术后6月乳房的美学评价等数据。结果实验组30例患者,三维可视技术能准确反映其乳房及肿瘤、背阔肌及胸背血管等解剖结构及其三维毗邻关系。30例患者手术顺利,中位手术时间为226 min(205~253 min),术中中位出血量为95 m L(73~132 m L)。乳房美学评价,22例优,6例良,2例一般。对照组18例患者,中位手术时间为283 min(256~313 min),中位出血量为107 m L(79~147 m L)。乳房美学评价,10例优,4例良,4例一般。结论三维可视技术能很好的显示背阔肌形态及胸背动脉走行,可计算乳房体积及背阔肌体积,指导背阔肌切取范围,避免误伤背阔肌瓣蒂部血管,缩短手术时间,减少术中出血,术后乳房重建效果良好。
