BACKGROUND:Polycythemia vera is defined as a chronic myeloproliferative disorder characterized by increased red blood cell count.There have been no reports on mesenteric thrombosis resulting from iatrogenic polycythem...BACKGROUND:Polycythemia vera is defined as a chronic myeloproliferative disorder characterized by increased red blood cell count.There have been no reports on mesenteric thrombosis resulting from iatrogenic polycythemia.METHODS:We present a patient with a history of non-small cell lung cancer undergoing maintenance oral chemotherapy on tarceva and adjunctive use of procrit.The patient presented to our emergency department with an acute abdomen and was found to have ischemic bowel from unmonitored procrit,which lead to hyperviscosity of blood and mesenteric infarction.RESULTS:The patient remained intubated with ventilator support.He refused a tracheostomy.He continued on feeding through the J port of the nasojejunal tube.His white cell count,and hematocrit and creatinine levels remained normal.Procrit use and chemotherapy were not restarted.He was transferred to a subacute nursing facility for further treatment.CONCLUSIONS:Procrit and other erythropoiesis stimulating drugs can cause significant morbidity and mortality with an increased risk of cardiovascular events,gastrointestinal bleeding,thromboembolism and stroke.This case report suggests that without closely monitoring hematocrit levels,epoetin may also be associated with an increased risk of mesenteric infarction.展开更多
Late vascular complications involving aorta are rare but devastating adversities following anterior thoracic spine operations are present.The current article describes our experience with one such patient who had an i...Late vascular complications involving aorta are rare but devastating adversities following anterior thoracic spine operations are present.The current article describes our experience with one such patient who had an iatrogenic pseudoaneurysm of the thoracic aorta,mimicking infection.The patient was treated successfully following concomitant efforts by multidisciplinary experts with shunting.We wish to highlight upon the significance of recognizing the possible sinister consequences of a dangerously prominent spinal implant and the role of a suspicious surgeon in identifying these menacing complications at the right time.展开更多
文摘BACKGROUND:Polycythemia vera is defined as a chronic myeloproliferative disorder characterized by increased red blood cell count.There have been no reports on mesenteric thrombosis resulting from iatrogenic polycythemia.METHODS:We present a patient with a history of non-small cell lung cancer undergoing maintenance oral chemotherapy on tarceva and adjunctive use of procrit.The patient presented to our emergency department with an acute abdomen and was found to have ischemic bowel from unmonitored procrit,which lead to hyperviscosity of blood and mesenteric infarction.RESULTS:The patient remained intubated with ventilator support.He refused a tracheostomy.He continued on feeding through the J port of the nasojejunal tube.His white cell count,and hematocrit and creatinine levels remained normal.Procrit use and chemotherapy were not restarted.He was transferred to a subacute nursing facility for further treatment.CONCLUSIONS:Procrit and other erythropoiesis stimulating drugs can cause significant morbidity and mortality with an increased risk of cardiovascular events,gastrointestinal bleeding,thromboembolism and stroke.This case report suggests that without closely monitoring hematocrit levels,epoetin may also be associated with an increased risk of mesenteric infarction.
文摘Late vascular complications involving aorta are rare but devastating adversities following anterior thoracic spine operations are present.The current article describes our experience with one such patient who had an iatrogenic pseudoaneurysm of the thoracic aorta,mimicking infection.The patient was treated successfully following concomitant efforts by multidisciplinary experts with shunting.We wish to highlight upon the significance of recognizing the possible sinister consequences of a dangerously prominent spinal implant and the role of a suspicious surgeon in identifying these menacing complications at the right time.
