A patient with advanced lung adenocarcinoma who was unable to tolerate chemotherapy was controlled after combined treatment with apatinib.This case provides a basis for the treatment of this disease using this method....A patient with advanced lung adenocarcinoma who was unable to tolerate chemotherapy was controlled after combined treatment with apatinib.This case provides a basis for the treatment of this disease using this method.Methods:The diagnosis of patients with lung adenocarcinoma stageⅣperiod,age,detection of EGFR mutations,line for treatment in September there progress,a large number of pleural effusions,the right lung neoplasm,cisplatin and interleukin-2 pleural perfusion chemotherapy,line again.Assessment of the EGFR gene exon 20 single did not identify a missense mutation(T790M not mutation).Patients with high collar,poor health,refused chemotherapy.Subsequently,we administered oral treatment of apatinib at 250 mg/day.Conclusion:Apatinib combined with EGFR-TKI targeted therapy is effective for lung adenocarcinoma.Moreover,adverse reactions can be controlled.展开更多
文摘A patient with advanced lung adenocarcinoma who was unable to tolerate chemotherapy was controlled after combined treatment with apatinib.This case provides a basis for the treatment of this disease using this method.Methods:The diagnosis of patients with lung adenocarcinoma stageⅣperiod,age,detection of EGFR mutations,line for treatment in September there progress,a large number of pleural effusions,the right lung neoplasm,cisplatin and interleukin-2 pleural perfusion chemotherapy,line again.Assessment of the EGFR gene exon 20 single did not identify a missense mutation(T790M not mutation).Patients with high collar,poor health,refused chemotherapy.Subsequently,we administered oral treatment of apatinib at 250 mg/day.Conclusion:Apatinib combined with EGFR-TKI targeted therapy is effective for lung adenocarcinoma.Moreover,adverse reactions can be controlled.
