[Objectives]To study the protective effect of Mongolian medicine Youning Bawei Powder on liver injury induced by carbon tetrachloride(CCl_(4))in mice.[Methods]The experimental mice were divided into 5 groups:normal gr...[Objectives]To study the protective effect of Mongolian medicine Youning Bawei Powder on liver injury induced by carbon tetrachloride(CCl_(4))in mice.[Methods]The experimental mice were divided into 5 groups:normal group,model group,positive control group,low-dose group and high-dose group of Mongolian medicine Youning Bawei Powder.The model group was induced by CCl_(4),the positive control group was treated with liver-protecting tablet,and the Mongolian medicine group was treated with Youning Bawei Powder for one month.The liver tissue injury of mice in each group was observed by HE staining,and the levels of serum ALT,AST,SOD and MDA were detected.[Results]Mongolian medicine Youning Bawei Powder significantly improved the pathological liver injury induced by CCl_(4),significantly decreased the content of ALT,AST and MDA in serum of mice with CCl_(4) liver injury,and significantly increased the activity of serum SOD.[Conclusions]Youning Bawei Powder,a Mongolian medicine,has a protective effect on liver injury induced by CCl_(4) in mice.展开更多
This study explored how bitter melon powder （BMP） alters the colonic microenvironment during the development of obesity-associated fatty liver in rats. We observed that BMP effectively inhibited the body weight gain...This study explored how bitter melon powder （BMP） alters the colonic microenvironment during the development of obesity-associated fatty liver in rats. We observed that BMP effectively inhibited the body weight gain and lipid accumulation in the liver, ameliorated glucose intolerance, and increased the colon weight after an 8-week treatment compared to that in the high-fat diet （HFD） group. BMP significantly decreased fecal water toxicity towards HT-29 cells, as revealed by the cell counting kit （CCK）-8 assay results, and the mRNA expression of Toll-like receptor 4 （TLR4） in colon mucosa. Additionally, gut permeability in the BMP group was restored to normal levels. Finally, BMP alleviated the inflammatory state of the rat colon mucosa and liver tissues as well as the systemic inflammation.展开更多
Fluorine in mold powder is known as harmful to human health and the environment. Being the advocate of green production, Baosteel developed an environmentally friendly mold powder without fluorine. The main problem of...Fluorine in mold powder is known as harmful to human health and the environment. Being the advocate of green production, Baosteel developed an environmentally friendly mold powder without fluorine. The main problem of fluorine-free flux film is small heat resistance and thus the heat transfer intensity of the mold is too large, which to some extent hinders the increase of the casting speed. With the heat flow simulation equipment, controlling precipitation of crystal in flux and solidification temperature properly, fluorine-free mold powder for low carbon steel,which substitutes F with B203 ,was successfully developed and applied in industrial production. The production results show that, by using boronic fluorine-free mold powder,the boron increment in molten steel is less than 1.3ppm for conventional aluminium killed low carbon steel.展开更多
To improve the economic and social benefits of mining and backfill,it is necessary to find the backfill materials suitable for mineral mining,improve the various properties of the filling materials,and develop low cos...To improve the economic and social benefits of mining and backfill,it is necessary to find the backfill materials suitable for mineral mining,improve the various properties of the filling materials,and develop low cost,high performance new filling materials.Portland cement is neither environmentally friendly nor economical.Currently,we have begun to study and apply some industrial waste,such as slag,fly ash,and other solid wastes,with certain activities as the primary component of cementing material that will not only meet the technical requirements of filling,but also comprehensively utilize industrial waste and possess a benign,sustainable lifecycle for environmental protection.This study expounds the composition and reaction mechanism of alkali-activated binder powder used for cemented paste backfill material,summarizes the research and application status of alkaliactivated binder powders,including mechanics,durability,economic and environmental,and discusses future development directions for mine binder powders.It needs to continue to expand the utilization range of solid waste and improve the utilization rate of solid waste in the future.The development and research of this binder powder plays an important role in the progress of filling technologies.Hence,the research about alkali-activated binder powder contains great development potential and broad prospects.展开更多
Due to large volume and high hardness of thermal insulation materials mostly used in high temperature fields, a composite cooling powder and its thixotropic hydrogel for thermal protection are presented. The core of c...Due to large volume and high hardness of thermal insulation materials mostly used in high temperature fields, a composite cooling powder and its thixotropic hydrogel for thermal protection are presented. The core of composite cooling material powder is super absorbent polymer, composing with metal salt, polysaccharide hydrosol and inorganic particles and other modifiers through a series of composite process, which can be easily stored for a long time. When needed, the powder can be mixed with water to obtain a kind of thixotropic hydrogel in a very short time. Experimental results show this thermal protection technology with thixotropic ability has excellent thermal protection performance, meanwhile flexible, adhesive and low cost, which exerts instantaneous cooling, efficient thermal protection and long-lasting flame-retardant protection.展开更多
基金the Fourth Batch of National Excellent Talents Research and Training Project of Traditional Chinese Medicine(Minority Medicine)[GuoZhongYiYaoRenJiaoHan(2019)28]National Key Research and Development Program of China(2017YFC1703900).
文摘[Objectives]To study the protective effect of Mongolian medicine Youning Bawei Powder on liver injury induced by carbon tetrachloride(CCl_(4))in mice.[Methods]The experimental mice were divided into 5 groups:normal group,model group,positive control group,low-dose group and high-dose group of Mongolian medicine Youning Bawei Powder.The model group was induced by CCl_(4),the positive control group was treated with liver-protecting tablet,and the Mongolian medicine group was treated with Youning Bawei Powder for one month.The liver tissue injury of mice in each group was observed by HE staining,and the levels of serum ALT,AST,SOD and MDA were detected.[Results]Mongolian medicine Youning Bawei Powder significantly improved the pathological liver injury induced by CCl_(4),significantly decreased the content of ALT,AST and MDA in serum of mice with CCl_(4) liver injury,and significantly increased the activity of serum SOD.[Conclusions]Youning Bawei Powder,a Mongolian medicine,has a protective effect on liver injury induced by CCl_(4) in mice.
基金supported by the National Natural Science Foundation of China(31371760)the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)
文摘This study explored how bitter melon powder （BMP） alters the colonic microenvironment during the development of obesity-associated fatty liver in rats. We observed that BMP effectively inhibited the body weight gain and lipid accumulation in the liver, ameliorated glucose intolerance, and increased the colon weight after an 8-week treatment compared to that in the high-fat diet （HFD） group. BMP significantly decreased fecal water toxicity towards HT-29 cells, as revealed by the cell counting kit （CCK）-8 assay results, and the mRNA expression of Toll-like receptor 4 （TLR4） in colon mucosa. Additionally, gut permeability in the BMP group was restored to normal levels. Finally, BMP alleviated the inflammatory state of the rat colon mucosa and liver tissues as well as the systemic inflammation.
文摘Fluorine in mold powder is known as harmful to human health and the environment. Being the advocate of green production, Baosteel developed an environmentally friendly mold powder without fluorine. The main problem of fluorine-free flux film is small heat resistance and thus the heat transfer intensity of the mold is too large, which to some extent hinders the increase of the casting speed. With the heat flow simulation equipment, controlling precipitation of crystal in flux and solidification temperature properly, fluorine-free mold powder for low carbon steel,which substitutes F with B203 ,was successfully developed and applied in industrial production. The production results show that, by using boronic fluorine-free mold powder,the boron increment in molten steel is less than 1.3ppm for conventional aluminium killed low carbon steel.
基金This work was financially supported by the Beijing Municipal Natural Science Foundation(No.2204087)This research was also supported by grants from the National Natural Science Foundation of China(No.51834001).
文摘To improve the economic and social benefits of mining and backfill,it is necessary to find the backfill materials suitable for mineral mining,improve the various properties of the filling materials,and develop low cost,high performance new filling materials.Portland cement is neither environmentally friendly nor economical.Currently,we have begun to study and apply some industrial waste,such as slag,fly ash,and other solid wastes,with certain activities as the primary component of cementing material that will not only meet the technical requirements of filling,but also comprehensively utilize industrial waste and possess a benign,sustainable lifecycle for environmental protection.This study expounds the composition and reaction mechanism of alkali-activated binder powder used for cemented paste backfill material,summarizes the research and application status of alkaliactivated binder powders,including mechanics,durability,economic and environmental,and discusses future development directions for mine binder powders.It needs to continue to expand the utilization range of solid waste and improve the utilization rate of solid waste in the future.The development and research of this binder powder plays an important role in the progress of filling technologies.Hence,the research about alkali-activated binder powder contains great development potential and broad prospects.
文摘Due to large volume and high hardness of thermal insulation materials mostly used in high temperature fields, a composite cooling powder and its thixotropic hydrogel for thermal protection are presented. The core of composite cooling material powder is super absorbent polymer, composing with metal salt, polysaccharide hydrosol and inorganic particles and other modifiers through a series of composite process, which can be easily stored for a long time. When needed, the powder can be mixed with water to obtain a kind of thixotropic hydrogel in a very short time. Experimental results show this thermal protection technology with thixotropic ability has excellent thermal protection performance, meanwhile flexible, adhesive and low cost, which exerts instantaneous cooling, efficient thermal protection and long-lasting flame-retardant protection.
