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Perianal Giant Condyloma Acuminatum:A Case Report
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作者 张晨光 罗儒卓 宁回中 《Chinese Journal of Cancer Research》 SCIE CAS CSCD 2007年第3期227-229,共3页
Rare giant condyloma acuminatum (CA) reported by this paper is an interesting unusual case in China. Giant CA is a tumor that primarily affects the genital and perianal areas. Its feature is the high rate of local r... Rare giant condyloma acuminatum (CA) reported by this paper is an interesting unusual case in China. Giant CA is a tumor that primarily affects the genital and perianal areas. Its feature is the high rate of local recurrence and transformation into squamous cell carcinoma. Making choice of wide surgical excision and using interferon as antiviral and immunoenhancement for CA after operation, we obtain satisfactory functional and cosmetic results. 展开更多
关键词 Giant condyloma acuminatum Skin Lesion feature Operation Immunizator
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Clinical Profile and Significance of Mucocutaneous Lesions of Primary Sjogren's Syndrome: A Large Cross-sectional Study with 874 Patients 被引量:2
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作者 Lei Xuan Yi-Dong Zhang +4 位作者 Li Li Yue-Ping Zeng Hao-Ze Zhang Jing Wang Zhen-Hua Dong 《Chinese Medical Journal》 SCIE CAS CSCD 2017年第20期2423-2428,共6页
Background: Mucocutaneous lesions are common features of primary Sjogren's syndrome (pSS), but only a few studies have focused on them. To demonstrate the profile ofmucocutaneous lesions ofpSS and further explore ... Background: Mucocutaneous lesions are common features of primary Sjogren's syndrome (pSS), but only a few studies have focused on them. To demonstrate the profile ofmucocutaneous lesions ofpSS and further explore their potential clinical significance, we perfermed a cross-sectional study on 874 patients. Methods: Demographic data, clinical manifestations, and laboratory results of 874 pSS patients were collected. Patients were divided into two groups according to the presence of mucocutaneous lesions. Differences in primary symptoms and systemic impairments between the two groups were analyzed. Results of laboratory tests were also compared alter excluding those who had taken corticosteroid from both groups. One-year follow-up was done, and occurrences of various new complications were compared. Results: Among the 874 pSS patients, 181 patients had mucocutaneous lesions, accounting for 20.7%. Multiple mucocutaneous manifestations were displayed, and the top four most common types of lesions were purpuric eruptions (39.8%), urticaria (23.8%), Raynaud's phenomenon (14.9%), and angular stomatitis (9.9%). Incidences of pulmonary interstitial fibrosis, pulmonary bullae, leukopenia, and anemia were significantly higher among patients with mucocutaneous lesions (P 〈 0.05). Increase in lgG and decrease in C4 among patients with mucocutaneous lesions displayed statistical significance after excluding patients from both groups who had taken corticosteroid (P 〈 0.05). Alter one-year follow-up, patients with mucocutaneous lesions presented a slightly higher incidence of new complications compared to those without. Conclusions: Mucocutaneous manifestations ofpSS patients were common and diverse. Patients with mucocutaneous manifestations had more systemic damages, higher level of IgG, and lower level of serum C4, suggesting a higher activity of the primary disease. 展开更多
关键词 Clinical features: Clinical Significance: Mucocutaneous lesions Primary Sjogren's Syndrome
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