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Effect of psychological nursing interventions on effectiveness and quality of life in schizophrenia patients receiving modified electroconvulsive therapy
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作者 Jing Lu 《World Journal of Clinical Cases》 SCIE 2024年第16期2751-2757,共7页
BACKGROUND Schizophrenia is a common and severe mental disorder characterized by severe thought disturbances,hallucinations,delusions,and emotional instability.For some patients,conventional treatment methods may not ... BACKGROUND Schizophrenia is a common and severe mental disorder characterized by severe thought disturbances,hallucinations,delusions,and emotional instability.For some patients,conventional treatment methods may not effectively alleviate symptoms,necessitating the use of alternative therapeutic approaches.Modified electroconvulsive therapy(MECT)is an effective treatment modality for schizophrenia,inducing anti-depressive and antipsychotic effects through the stimulation of brain electrical activity.AIM To explore the impact of psychological nursing intervention(PNI)before and after MECT on the efficacy and quality of life of patients with schizophrenia.METHODS Eighty patients with schizophrenia who received MECT treatment from 2021 to 2023 were randomly divided into two groups:The intervention group(n=40)and the control group(n=40).The intervention group received PNI before and after MECT,while the control group received routine nursing care.The efficacy of MECT was evaluated by the Positive and Negative Syndrome Scale(PANSS)and the Clinical Global Impression Scale(CGI)before and after the treatment.The quality of life was assessed by the Short Form 36 Health Survey(SF-36)after the treatment.RESUITS The intervention group had significantly lower scores of PANSS and CGI than the control group after the treatment(P<0.05).The intervention group also had significantly higher scores of SF-36 than the control group in all domains except physical functioning(P<0.05).CONCLUSION PNI before and after MECT can improve the efficacy and quality of life of patients with schizophrenia.It is suggested that nurses should provide individualized and comprehensive psychological care for patients undergoing MECT to enhance their recovery and well-being. 展开更多
关键词 Psychological nursing interventions Modified electroconvulsive therapy SCHIZOPHRENIA EFFICACY quality of life Positive and negative syndrome scale
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Development of the Scale of Quality of Life for Diseases with Visual Impairment
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作者 Qiang Yu, Shaozhen Li, Henian Chen, Tiancai Ye, Jingjing AoZhongzhan Ophthalmic center, Sun Yat-sen University of Medical Sciences, Guangzhou 510060, China The First Millitary Medical University, Guangzhou 510515,China. 《Eye Science》 CAS 1996年第1期36-39,共4页
Purpose :To describe the development of the of scale quality of life which can measure the quality of life of Chinese patients with visual impairment. Methods: Based on a thorough literature search and consultation wi... Purpose :To describe the development of the of scale quality of life which can measure the quality of life of Chinese patients with visual impairment. Methods: Based on a thorough literature search and consultation with ophthalmologists and public health professionals, 20 items were selected to create a scale. Fifty-seven cataract patients with vision impairment and 60 glaucoma patients with vision impairment and visual field loss were measured by the scale to evaluate the validity, reliability and responsiveness of the scale.Results: The scale covered four domains of the quality of life(QOL). The criterion related validity of the scale: r = 0. 6865 (P=0. 001). The test-retest reliability of the scale: r = 0. 8959(P = 0. 001). Coronback’s alpha was 0. 9359. The variance ratio (VR) of intra-individual variance to inter- individual variance was 0. 0551 for overall scores. The correlation coefficient of split-half method was 0. 9553. The responsiveness; T-test, T = 5. 95 (P = 0. 001), effect size 展开更多
关键词 quality of life scale CATARACT GLAUCOMA
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Quality of life in adult intermittent exotropia and the risk factors 被引量:2
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作者 Bo-Wen Zhao Jing Fu +5 位作者 Jing-Hui Wang Hai-Xia Bai Pei-Pei Liu Ya-Nan Guo Rong-Han Zhang Han Su 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2021年第3期442-447,共6页
AIM: To study the quality of life of adult patients with intermittent exotropia(IXT) in China and analyze the factors affecting the quality of life in IXT patients.METHODS: Total y 109 cases of normal eye(control grou... AIM: To study the quality of life of adult patients with intermittent exotropia(IXT) in China and analyze the factors affecting the quality of life in IXT patients.METHODS: Total y 109 cases of normal eye(control group), 77 cases of IXT(IXT group) and 115 cases of strabismus control group(except IXT) were collected. The quality of life of the patients was assessed by Chinese version of adult strabismus patient’s quality of life scale(CAS-20). The differences of general characteristics, visual function and quality of life were analyzed, and the effects of individual factors and visual function on quality of life of patients with IXT were analyzed.RESULTS: The IXT group had a high proportion of patients with family history, low proportion of patients with amblyopia compared with strabismus control group. The proportion with normal near and far stereopsis of IXT group were lower than that of normal control group. The best corrected visual acuity of IXT group was higher than that of strabismus control group, but lower than the control group. In addition, the median strabismus degree in IXT group was higher than that in other strabismus control group. The median psychosocial scores and median visual function scores of the IXT group was lower than that of the normal control group, but not different from strabismus control group. Occupation status, course of disease, far stereopsis and near stereopsis significantly affected the quality of life in IXT patients.CONCLUSION: Adult IXT patients in China have a certain proportion of family history and lower quality of life, The main factors affecting the quality of life of IXT patients is stereopsis, course of disease and occupation status. 展开更多
关键词 intermittent exotropia quality of life scale binocular function
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Health-related quality of life in Parkinson's disease patients in northeastern Sicily, Italy An ecological perspective 被引量:1
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作者 Letteria Spadaro Lilla Bonanno +2 位作者 Giuseppe Di Lorenzo Placido Bramanti Silvia Marino 《Neural Regeneration Research》 SCIE CAS CSCD 2013年第17期1615-1622,共8页
Parkinson's disease has a negative impact on health-related quality of life in Parkinson's disease patients. Depression, cognitive impairment, coping strategies, dyskinesia, gait disorders and complications of dopam... Parkinson's disease has a negative impact on health-related quality of life in Parkinson's disease patients. Depression, cognitive impairment, coping strategies, dyskinesia, gait disorders and complications of dopaminergic drugs are the variables that most affect health-related quality of life. The ecological model of human development focuses attention on both individual and social environmental factors as targets for health interventions. From this perspective, the aim of this cross-sectional survey was to evaluate the influence of gender, family size and perceived autonomy on health-related quality of life in Parkinson's disease patients in nOrtheastern Sicily, Italy. Ninety Parkinson's disease patients, attending the Movement Disorders Clinic at IRCCS Centro Neurolesi "Bonino-Pulejo" (Messina), were consecutively enrolled. The Unified Parkinson Disease Rating Scale motor subscale (UPDRS-Ⅲ) scores, the Parkinson Disease Questionnaire-39 Item scores (as a disease-specific measure of health-related quality of life), scores on the Short Form (36) Health Survey Questionnaire (as a generic measure), and answers to a brief checklist were recorded. A total of 85 Parkinson's disease patients (49% males and 51% females; mean age 70.8 ± 8.6 years mean UPDRS-Ⅲ 24.15 ± 6.55; mean disease duration 5.52 ± 4.65 years) completed the booklet of questionnaires. In the multivariate regression analysis, we included clinical and social variables as independent predictors of health-related quality of life. Our results suggest a potential compounding effect of ecological intrapersonal and interpersonal levels on health-related quality of life outcomes. Gender, self-evaluated autonomy and family size significantly impacted health-related quality of life. If quality of life is used as an indicator of treatment outcomes, an ecological perspective of the case history will be important to disclose relevant prognostic information and trigger personalized health care interventions. 展开更多
关键词 neural regeneration neurodegenerative disease health-related quality of life Parkinson's disease ecological model Parkinson's Disease Questionnaire-39 Items social variables the UnifiedParkinson Disease Rating scale motor subscales CAREGIVER grants-supported paper
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Health Related Quality of Life and Mental Health in ICU Survivors: Post-Intensive Care Syndrome Follow-Up and Correlations between the 36-Item Short Form Health Survey (SF-36) and the General Health Questionnaire (GHQ-28) 被引量:1
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作者 Stefano Tugnoli Savino Spadaro +3 位作者 Francesca Dalla Corte Giorgia Valpiani Carlo Alberto Volta Stefano Caracciolo 《Health》 CAS 2022年第5期477-506,共30页
We investigated the relationship between health-related quality of life (HRQOL) and psychological distress in intensive care unit (ICU) survivors 12 months after ICU discharge. The purpose of this study, conducted and... We investigated the relationship between health-related quality of life (HRQOL) and psychological distress in intensive care unit (ICU) survivors 12 months after ICU discharge. The purpose of this study, conducted and completed before the onset of the COVID-19 pandemic, was to find correlations among psychiatric symptoms detected by a screening tool as the General Health Questionnaire-28 (GHQ-28) and the different domains of HRQOL measured with the SF-36 health survey (SF-36), in order to identify ICU survivors with Post-Intensive Care Syndrome (PICS) who need a specific psychiatric intervention to improve their HRQOL. Among 298 ICU survivors who stayed in the ICU for at least 72 hours, 48 patients were enrolled one year after discharge undergoing a clinical interview to assess their functional impairment (Barthel index), mental health (GHQ-28), and health-related quality of life (SF-36). 19% of those subjects had a GHQ-28 ≥ 5 and were identified as “psychiatric cases”, and they were older and experienced a greater impairment in HRQOL. Anxiety, insomnia, and depressive symptoms seemed to be particularly involved in the impairment of HRQOL. A negative correlation between GHQ-28 total scores and subscales and SF-36 subscales was found. Our findings highlighted that psychological distress in ICU survivors may negatively impact physical health recovery and quality of life;conversely, physical impairment and functional disability may trigger the onset of psychiatric symptoms after discharge. The present study is firstly to investigate the correlations between HRQOL and psychological distress in ICU survivors through the GHQ-28, and then affirms the need to carry out follow-up checks for psychiatric symptoms in ICU survivors. 展开更多
关键词 ICU Survivors Psychological Distress Health-Related quality of life SF-36 Health Survey scaled General Health Questionnaire (GHQ-28)
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Italian Psychometric Validation of the Multidimensional Students’ Health-Promoting Lifestyle Profile Scale
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作者 Giulia Savarese Luna Carpinelli +1 位作者 Pierpaolo Cavallo Maria Prosperina Vitale 《Health》 2018年第11期1554-1575,共22页
The present study examines the factorial structure and assesses the psychometric properties of the adapted multidimensional Health-Promoting Lifestyle Profile II Scale, considering a sample of Italian university stude... The present study examines the factorial structure and assesses the psychometric properties of the adapted multidimensional Health-Promoting Lifestyle Profile II Scale, considering a sample of Italian university students who participated to an online survey. The original 52-items Scale showed a high overall internal consistency. Four of the six subscales were associated with good values of the Cronbach’s α coefficient, whereas two subscales had lower values. Hence corrected item-total correlation was calculated and 26 items that decreased the scale’s reliability were deleted. The remaining 26 items were first subjected to Principal Component Analysis that suggested a conceptually meaningful five-factor model. This result was further supported by the first-order confirmatory factor analysis, in which all the factor loadings were statistically significant. The internal consistency and the composite reliability for the reduced version of the Scale and its subscales have shown a good reliability for the measurement models. The multidimensionality of the scale was also confirmed by a second-order factor model. 展开更多
关键词 scale Reliability and Validity Confirmatory Factor Analysis HEALTH PROMOTION and quality of life University STUDENTS
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Parents’ Perceptions and Judgment Formation Process of Their Infants’ Quality of Life
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作者 Mari Ikeda Iori Sato +4 位作者 Takafumi Soejima Ami Setoyama Kyoko Kobayashi Rieko Fukuzawa Kiyoko Kamibeppu 《Open Journal of Nursing》 2020年第12期1219-1232,共14页
<strong>Purpose:</strong> We explored parents’ perceptions and judgment formation processes concerning their infants’ health-related quality of life (HRQOL). <strong>Method:</strong> The Peds... <strong>Purpose:</strong> We explored parents’ perceptions and judgment formation processes concerning their infants’ health-related quality of life (HRQOL). <strong>Method:</strong> The PedsQL<sup>TM</sup> Infant Scales—an instrument specifically designed for infants aged 1 - 24 months—were translated into Japanese. Forward and backward translations were performed, evaluating the semantic and conceptual equivalencies. Parents with infants younger than two-years-old were recruited and interviewed using think-aloud and probing techniques. Participants completed the questionnaire while speaking aloud about what came to their mind, what they thought each question meant, and how they reached each answer. <strong>Results:</strong> Seven mothers and three fathers participated. The median age was 33.4 (28 - 43) years. Four had infants younger than six-months-old. All infants were healthy. Parents’ perceptions of their infants’ HRQOL varied across their ages. Some parents with infants younger than six months experienced difficulty discussing “emotional functioning” and “cognitive functioning” because their infants were too young to articulate the actions mentioned in the items. In those cases, the parents responded, “never a problem”. Seventy-five percent of parents recalled their infants’ daily “physical functioning”, while only 58% recalled “physical symptoms”. Some parents’ perceptions and judgment formation were compromised by their own perceptions. For example, they answered “often a problem” when the items were problematic to themselves instead of to their child. However, many distinguished their infants’ HRQOL from their own perceptions, indicating they understood the intention of the questionnaire. <strong>Conclusion:</strong> Parents’ formed judgement may compromise by their own perceptions. The result of this study will be helpful in improving healthcare communication and interpreting parents’ judgments of their infants’ HRQOL in future studies. 展开更多
关键词 Health-Related quality of life INFANT Judgment Formation Perception scale Translation
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Application of Quality of Life Scale in Hematological Disease Research
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作者 Zongyan Du Wenling Yao +1 位作者 Min Li Ping Li 《Journal of Clinical and Nursing Research》 2019年第5期29-33,共5页
Quality of life research is an emerging and rapidly developing health measurement technology.Quality of life assessment is performed using scales.Accurate quality of life assessment provides comprehensive information ... Quality of life research is an emerging and rapidly developing health measurement technology.Quality of life assessment is performed using scales.Accurate quality of life assessment provides comprehensive information of patient which allows clinicians to put emphasis on overall quality of life(Total QOL)of patient.Quality of life scales have been applied for analysis of diseases such as leukemia and immune thrombocytopenia.This article reviews the use of commonly used quality of life scales for hematological diseases. 展开更多
关键词 quality of life scale HEMATOLOGICAL DISEASE
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Quality of life and emotional change for middle -aged and elderly patients with diabetic retinopathy 被引量:8
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作者 Yao Yu Lie Feng +4 位作者 Yi Shao Ping Tu He-Ping Wu Xun Ding Wei-Hua Xiao 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2013年第1期71-74,共4页
AIM:To evaluate the SF-36, Diabetes Specificity Quality of Life Scale (DSQL) and anxiety and depression symptoms and investigate its changes in proliferative diabetic retinopathy (PDR) by vitrectomy interventions. MET... AIM:To evaluate the SF-36, Diabetes Specificity Quality of Life Scale (DSQL) and anxiety and depression symptoms and investigate its changes in proliferative diabetic retinopathy (PDR) by vitrectomy interventions. METHODS:The present study included 108 diabetic retinopathy (DR) patients:54 with PDR and 54 with non-proliferative diabetic retinopathy (NPDR). Each healthy control group (n =54) sociodemographically matched to DR groups was established respectively. The quality of life, anxiety and depression symptoms were evaluated and analyzed on preoperative and postoperative month 1 using SF-36, DSQL and Hospital Anxiety and Depression Scale (HADS). · RESULTS:DR patients described impaired HRQL (Health Related Quality of life, SF -36) in 6 out of 8 subscales, including ‘Body Health’, ‘Body RoleFunction’,‘General Health’,‘Society Function’,‘Emotion Role Function’and‘Mental Health’. Compared with controls, DR patients (NPDR and PDR) suffered from statistically significantly impaired HRQL (SF-36 Summary score) (P【 0.05). By surgical intervention, the anxiety and depression score were significantly reduced, while the health and quality of life (SF-36 Summary scores and DSQL scores) was improved in patients with PDR (P 【0.05). CONCLUSION:DR patients were affected in mentation and quality of life. Surgery interventions can improve SF-36, DSQL, anxiety and depression in PDR patients. 展开更多
关键词 diabetic retinopathy SF-36 diabetes specificity quality of life scale hospital anxiety and depression scale VITRECTOMY
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Defecation function and quality of life in patients with slow-transit constipation after colectomy 被引量:15
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作者 Yue Tian Li Wang +6 位作者 Jing-Wang Ye Yong Zhang Hui-Chao Zheng Hao-De Shen Fan Li Bao-Hua Liu Wei-Dong Tong 《World Journal of Clinical Cases》 SCIE 2020年第10期1897-1907,共11页
BACKGROUND Although total or subtotal colectomy for slow-transit constipation(STC)has been proven to be a definite treatment,the associated defecation function and quality of life(QOL)are rarely studied.AIM To evaluat... BACKGROUND Although total or subtotal colectomy for slow-transit constipation(STC)has been proven to be a definite treatment,the associated defecation function and quality of life(QOL)are rarely studied.AIM To evaluate the effectiveness of surgery for STC regarding defecation function and QOL.METHODS From March 2013 to September 2017,30 patients undergoing surgery for STC in our department were analyzed.Preoperative,intra-operative,and postoperative 3-mo,6-mo,1-year,and 2-year follow-up details were recorded.Defecation function was assessed by bowel movements,abdominal pain,bloating,straining,laxative,enema use,diarrhea,and the Wexner constipation and incontinence scales.QOL was evaluated using the gastrointestinal QOL index and the 36-item short form survey.RESULTS The majority of patients(93.1%,27/29)stated that they benefited from the operation at the 2-year follow-up.At each time point of the follow-up,the number of bowel movements per week significantly increased compared with that of the preoperative conditions(P<0.05).Similarly,compared with the preoperative values,a marked decline was observed in bloating,straining,laxative,and enema use at each time point of the follow-up(P<0.05).Postoperative diarrhea could be controlled effectively and notably improved at the 2-year follow-up.The Wexner incontinence scores at 6-mo,1-year,and 2-year were notably lower than those at the 3-mo follow-up(P<0.05).Compared with those of the preoperative findings,the Wexner constipation scores significantly decreased following surgery(P<0.05).Thus,it was reasonable to find that the gastrointestinal QOL index scores clearly increase(P<0.05)and that the 36-item short form survey results displayed considerable improvements in six spheres(role physical,role emotional,physical pain,vitality,mental health,and general health)following surgery.CONCLUSION Total or subtotal colectomy for STC is not only effective in alleviating constipation-related symptoms but also in enhancing patients’QOL. 展开更多
关键词 Slow-transit constipation COLECTOMY Defecation function Wexner constipation and incontinence scales quality of life Gastrointestinal quality of life index
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Eleven influential factors for quality of life in adults with epilepsy
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作者 Tongge Wang Hao Wang Jianhua Cheng 《Neural Regeneration Research》 SCIE CAS CSCD 2008年第4期422-426,共5页
BACKGROUND: Research focused on the quality of life of epileptic patients began only very recently in China; in particular, most research has focused on children, but less on epileptic adults. OBJECTIVE: To survey a... BACKGROUND: Research focused on the quality of life of epileptic patients began only very recently in China; in particular, most research has focused on children, but less on epileptic adults. OBJECTIVE: To survey and analyze 11 influential factors for quality of life in adults with epilepsy by using quality of life epilepsy-31 scale. DESIGN: Cross-sectional study. SETTING: Department of Neurology, First Hospital Affiliated to Jinan University; Department of Neurology, First Affiliated Hospital of Wenzhou Medical College. PARTICIPANTS: A total of 107 adults with epilepsy for longer than one year were selected from Department of Neurology, First Hospital Affiliated to Jinan University between March 2004 and December 2006. The included patients met the Classification and Diagnostic Criteria of Epileptic Attack published by International Anti-Epilepsy League in 1981, and they provided informed consent. METHODS: General states, including course, attack frequency, marriage status, educational level, occupational types, economic status, attack types, drug types, and drug amount, were recorded. There were seven aspects in the Quality of Life Epilepsy-31 scale, including attack worry, life satisfaction, emotion, vigor/tiredness, drug influence, cognitive function, and social function. The scores positively correlated with the quality of life. Possible influential factors for quality of life were analyzed by one-way ANOVA and multivariate regression analysis. MAIN OUTCOME MEASURES: Course, attack frequency, marriage status, educational level, occupational types, economic status, attack types, drug types, drug amount, age, and sex. RESULTS: A total of 107 epileptic patients were included in the final analysis. Influential factors for quality of life in epileptic adults included attack frequency, educational level, economic status, attack types, drug amount, age, and course of disease (P 〈 0.05). Among them, attack frequency negatively correlated with attack worry, life satisfaction, emotion, vigor/tiredness, cognitive function, social function, and total scores (P 〈 0.05); economic status positively correlated with emotion, social function, life satisfaction, and total scores (P 〈 0.05); educational level positively correlated with attack worry, cognitive function, and total scores (P 〈 0.05); course of disease negatively correlated with social function (P 〈 0.05); and age negatively correlated with life satisfaction (P 〈 0.05). Scores from partial seizures in cognitive function and drug influence were significantly higher than scores of general seizures (P 〈 0.05), and scores of single drug treatment compared to life satisfaction were also significantly higher than scores of multi-drug treatments (P 〈 0.05). CONCLUSION: Attack frequency, attack type, economic status, educational level, drug amount, age, and course of disease are influence factors for quality of life in epileptic adults. 展开更多
关键词 EPILEPSY quality of life ADULTS scale neural regeneration
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Ocular manifestations and quality of life in patients after hematopoietic stem cell transplantation
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作者 Shu-Xian Fan Wen-Hui Wang +5 位作者 Peng Zeng Ke-Zhi Huang Yu-Xin Hu Jing Wang Yi-Qing Li Jian-Hui Xiao 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2023年第7期1138-1144,共7页
AIM:To explore the relationship between ocular and systemic conditions and the impact of ocular complications on the quality of life(QOL)in patients after allogeneic hematopoietic stem cell transplantation(ALLO-HSCT).... AIM:To explore the relationship between ocular and systemic conditions and the impact of ocular complications on the quality of life(QOL)in patients after allogeneic hematopoietic stem cell transplantation(ALLO-HSCT).METHODS:Forty-four patients with severe hematopoietic disease were enrolled after ALLO-HSCT at our center from July 2018 to October 2020.They completed two questionnaires:the Ocular Surface Disease Index(OSDI)and the quality-of-life scale for Chinese patients with visual impairment(SQOL-DV1).Ocular conditions and systemic conditions were also assessed.RESULTS:Eye damage was correlated with total bilirubin(P=0.005),and gamma-glutamyl transferase(GGT)(P=0.021).There was no significant correlation between the overall QOL score and OSDI(P=0.8226)or SQOLDV1(P=0.9526)scores.The OSDI and the overall QOL score were not correlated with ocular conditions,including best-corrected visual acuity(BCVA),intraocular pressure,Schirmer tear test II,sodium fluorescein staining,tear film breakup time,and tear meniscus height.SQOLDV1 was correlated with BCVA(P=0.0007),sodium fluorescein staining(P=0.007),and tear film breakup time(P=0.0146).CONCLUSION:In some patients,early ocular symptoms are not evident after ALLO-HSCT,while ocular surface complications can be observed after a comprehensive ophthalmological examination.Especially for those with elevated total bilirubin or GGT,regular ophthalmic follow-up visits are essential to diagnose and treat ocular graft versus host disease(o GVHD),especially for patients with elevated total bilirubin or GGT. 展开更多
关键词 allogeneic stem cell transplantation ocular graft versus host disease ocular surface disease quality of life quality-of-life scale for Chinese patients with visual impairment Ocular Surface Disease Index
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Effect of ultra-low frequency repetitive transcranial magnetic stimulation on dysphagia in elderly patients with acute cerebral infarction and quality of life
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作者 Yun-Feng Yang Ju-Hua Liu +1 位作者 Li Liu Wen-Ju Dong 《Journal of Hainan Medical University》 2020年第3期54-59,共6页
Objective:To investigate the clinical effect of ultra-low frequency repetitive transcranial magnetic stimulation on dysphagia in elderly patients with acute cerebral infarction and its impact on quality of life.Method... Objective:To investigate the clinical effect of ultra-low frequency repetitive transcranial magnetic stimulation on dysphagia in elderly patients with acute cerebral infarction and its impact on quality of life.Methods:60 elderly patients with dysphagia caused by acute cerebral infarction were randomly divided into rTMS group and control group,30 cases in each group.Both groups received routine drug therapy and swallowing function training.rTMS group was additionally treated by ultra-low frequency(10mHZ)repetitive transcranial magnetic stimulation for 14 days.The changes of NIHSS score andADL score and NSE serum level and Wa Tian drinking water experiment and Fujishima Ichiro dysphagia scale score and SWAL-QOL score and SF-36 score were observed between the two groups before and after treatment.The clinical effect was evaluated by Wa Tian drinking water experiment.Results:After treatment,The clinical effective rate in rTMS group was significantly higher compared with that in the control group(P<0.05),NIHSS score and serum NSE level were significantly lower compared with the control group(P<0.05),ADL score and Fujishima Ichiro dysphagia score and SWAL-QOL score and SF-36 scores were significantly higher compared with the control group(P<0.05).After treatment,SF-36 total score(or SWAL-QOL Score)was negatively correlated with NSE serum level and NIHSS score,which was positively correlated with ADL score and Fujishima Ichiro dysphagia scale score score.Conclusion:Ultra-low frequency rTMS therapy can reduce NSE level,effectively improve dysphagia in elderly patients with acute cerebral infarction and significantly improve the elderly patients'life quality. 展开更多
关键词 Ultra-low Frequency REPETITIVE TRANSCRANIAL Magnetic Stimulation the elderly patient Acute cerebral INFARCTION DYSPHAGIA NSE SF-36 scale life quality
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Technology Transfer as the Process of Pharmaceutical Quality System: Modelling Technology Transfer as a Process Strategy
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作者 Valeriy Nikityuk Eugene Shakin Tatiana Yamikh 《Journal of Pharmacy and Pharmacology》 2017年第6期299-313,共15页
The recent GMP (good medical practice) rules actualisation and its requirements introduction widened the GMP guidelines for every life cycle of medicinal products, including the stage of processes scaling and techno... The recent GMP (good medical practice) rules actualisation and its requirements introduction widened the GMP guidelines for every life cycle of medicinal products, including the stage of processes scaling and technology transfer. This requires the technology transfer process to be regulated as the part of pharmaceutical quality system and the following development of corresponding written procedures. The following publication is dedicated to the development of TTP (technology transfer process) and its accessible graphic formalisation alongside the definition of main stages and possible procedures limited by the offered model. According to the actualized GMP rules, the technology transfer is an essential part of pharmaceutical quality system at a modem pharmaceutical company. 展开更多
关键词 MEDICINE life cycle technology transfer process scaling pharmaceutical quality system quality system procedures.
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Key Social Determinants to Narrow the Gap between Health-adjusted Life Expectancy and Life Expectancy in Megacities
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作者 XI Jun Yan CHEN Yuan Yuan +7 位作者 ZHANG Yu Qin LUO Ao DU Zhi Cheng LIANG Bo Heng DONG Hang LIN Xiao QIN Peng Zhe HAO Yuan Tao 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2022年第9期773-781,共9页
Objective Improvement in the quality of life is reflected in the narrowing of the gap between healthadjusted life expectancy(HALE)and life expectancy(LE).The effect of megacity expansion on narrowing the gap is rarely... Objective Improvement in the quality of life is reflected in the narrowing of the gap between healthadjusted life expectancy(HALE)and life expectancy(LE).The effect of megacity expansion on narrowing the gap is rarely reported.This study aimed to disclose this potential relationship.Methods Annual life tables were constructed from identified death records and population counts from multiple administrative sources in Guangzhou,China,from 2010 to 2020.Joinpoint regression was used to evaluate the temporal trend.Generalized principal component analysis and multilevel models were applied to examine the county-level association between the gap and social determinants.Results Although LE and HALE in megacities are increasing steadily,their gap is widening.Socioeconomic and health services are guaranteed to narrow this gap.Increasing personal wealth,a growing number of newborns and healthy immigrants,high urbanization,and healthy aging have helped in narrowing this gap.Conclusion In megacities,parallel LE and HALE growth should be highly considered to narrow their gap.Multiple social determinants need to be integrated as a whole to formulate public health plans. 展开更多
关键词 Generalized principal component analysis Health-adjusted life expectancy MEGACITIES quality of life Social determinants Temporal trend Urban expansion
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Development and Initial Validation of the Novel Scale for Assessing Quality of Life of Prostate Cancer Patients Receiving Androgen Deprivation Therapy 被引量:1
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作者 Yao-Jun Dun Hui-Xin Liu +5 位作者 Lu-Ping Yu Qing Li Xiao-Wei Zhang Xu Tang Cai-Peng Qin Tao Xu 《Chinese Medical Journal》 SCIE CAS CSCD 2017年第17期2082-2087,共6页
Background:There has been no a specific scale to measure quality of life (QOL) for prostate cancer patients receiving androgen deprivation therapy (ADT) to date.This study aimed to develop and initially validate ... Background:There has been no a specific scale to measure quality of life (QOL) for prostate cancer patients receiving androgen deprivation therapy (ADT) to date.This study aimed to develop and initially validate the scale to evaluate QOL for prostate cancer patients receiving ADT.Methods:The scale was developed following international recommendations.Moreover,the items were all generated through literature review and referenced questionnaires.After being reviewed by expert panelists,the revised scale was formed and then completed by a convenience sample of 200 prostate cancer patients from our hospital.Explore factor analysis (EFA) was applied to test the construct validity,then split-half reliability,Cronbach&#39;s alpha,and test-retest reliability were applied to assess the reliability and stability of the scale.Results:The revised scale contained 22 items and a total of 200 participants had completed the scale.One hundred participants were randomly selected from the total 200 participants to perform EFA with varimax rotation on the revised scale,and &quot;hot flashes&quot; item was deleted for low factor loading.We selected only 3 items from each factor,then,the final scale was formed with 18-items.We selected another 100 participants to perform the EFA again on the final scale.It was demonstrated that the structure with 6 factors explained 72.5% of total variance and factor loading value was above 0.40 in all items of the factors.Moreover,the split-half reliability coefficient,Cronbach&#39;s alpha,and test-retest reliability coefficient were calculated to be 0.74,0.63,and 0.89,respectively,exhibiting good reliability on the whole.Conclusions:The scale was identified to be a valid and reliable instrument to measure QOL for prostate cancer patients receiving ADT.Moreover,further research is needed to overcome the potential drawbacks. 展开更多
关键词 Androgen Deprivation therapy Exploratory Factor Analysis Prostate Cancer quality of life scale
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QOL Scale-AMILY在喉癌患者照顾者生活质量评价中的应用 被引量:23
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作者 刘益群 甘秀妮 +1 位作者 唐玮 李湘华 《中国全科医学》 CAS CSCD 北大核心 2009年第9期726-728,共3页
目的探讨由美国国家医学中心和贝克曼研究所研制的癌症患者照顾者生活质量量表(Quality of LifeFamily Version,QOLScale-FAMILY)用于中国喉癌患者照顾者生活质量测量的可能性,为喉癌患者照顾者生活质量的评定提供一个量化工具。方法通... 目的探讨由美国国家医学中心和贝克曼研究所研制的癌症患者照顾者生活质量量表(Quality of LifeFamily Version,QOLScale-FAMILY)用于中国喉癌患者照顾者生活质量测量的可能性,为喉癌患者照顾者生活质量的评定提供一个量化工具。方法通过对QOLScale-FAMILY量表的翻译、回译、文化调试制定出中文版的QOL Scale-FAMILY量表,并采用信访、电话访谈、面对面问卷访谈的方法,对100例喉癌患者照顾者(主要是患者配偶和子女)的生活质量进行测定,考核QOL Scale-FAMILY的可行性以及信度与效度。结果中文版的QOL Scale-FAMILY具有良好的内部一致性,总量表的Cronbach′sα系数为0.794,除了精神健康维度α=0.649外,其他3个维度满足群组比较的要求;重测信度γ=0.841。因子分析产生的4个公共因子与理论结构基本一致,结构效度的累积方差贡献率为60.2%。结论QOLScale-FAMILY中文版具有较好的信度和效度,对部分条目进行调整后,可以应用于喉癌患者照顾者生活质量的测定。 展开更多
关键词 QOL scale-FAMILY 喉癌患者照顾者 生活质量
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围绝经期评定量表Menopause Rating Scale(MRS)中文版信度及效度分析 被引量:11
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作者 黄琳 刘琴 刘月 《护理研究》 北大核心 2018年第21期3435-3437,共3页
[目的]测定围绝经期评定量表(MRS)中文版的信度和效度。[方法]应用MRS中文版对126例围绝经期女性进行测量,对测定结果进行信度和效度分析。[结果]MRS中文版总的Cronbach′sα系数为0.890,3个维度的Cronbach′sα系数为0.731~0.868;总... [目的]测定围绝经期评定量表(MRS)中文版的信度和效度。[方法]应用MRS中文版对126例围绝经期女性进行测量,对测定结果进行信度和效度分析。[结果]MRS中文版总的Cronbach′sα系数为0.890,3个维度的Cronbach′sα系数为0.731~0.868;总问卷的重测信度为0.887,3个维度的重测信度为0.661~0.883;探索性因子分析表明MRS中文版包括3个因子,共11个条目;3个因子可以解释总方差的73.68%;验证性因子分析显示数据拟合良好(χ2/df为1.170,近似误差均方根(RMSEA)为0.050,规范拟合指数(NFI)为0.894。[结论]MRS中文版具有良好的信度和效度,适合测量中国围绝经期妇女的生活质量。 展开更多
关键词 围绝经期 围绝经期评定量表(MRS) 生活质量 信度 效度
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中国西北地区老年高血压人群的健康相关生命质量研究
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作者 齐鸣瑞 王文娟 田利民 《中国全科医学》 CAS 北大核心 2025年第2期199-207,共9页
背景高血压在中国是一个日益严重的公共卫生问题,近年来越来越多的研究开始关注高血压老年人的生命质量,并探讨影响其生命质量的因素,对于制订有效的高血压健康管理计划意义重大。目的本研究旨在利用中文欧洲五维度量表(EQ-5D-5L)和中文... 背景高血压在中国是一个日益严重的公共卫生问题,近年来越来越多的研究开始关注高血压老年人的生命质量,并探讨影响其生命质量的因素,对于制订有效的高血压健康管理计划意义重大。目的本研究旨在利用中文欧洲五维度量表(EQ-5D-5L)和中文15D量表测量西北地区高血压老年人的健康效用值(HSU),评估健康相关生命质量(HRQoL),并探讨影响老年人HRQoL的主要因素。方法2021年在甘肃省兰州市随机招募2000名老年人,通过问卷调查、基础体检和实验室检查收集临床资料,采用EQ-5D-5L和15D量表测量HSU。采用亚组分析、Tobit回归和多元线性回归分析探究老年人HRQoL的影响因素。结果共有1784名老年人完整参与本次研究,其中50.9%的老年人血压正常,676名(37.9%)老年人为Ⅰ级高血压,152名(8.5%)为Ⅱ级高血压,48名(2.7%)为Ⅲ级高血压,这些患者的HSU在EQ-5D-5L中分别为0.949、0.942、0.933和0.921,在15D量表中分别为0.875、0.863、0.851和0.840。Tobit回归分析显示,在EQ-5D-5L中,性别、年龄、受教育年限、职业状态和年收入与老年人HSU相关(P<0.05),多元线性回归分析显示,在15D量表中,性别、年龄、受教育年限、高血压和饮酒与老年人HSU相关(P<0.05)。结论随着高血压分级的增加,EQ-5D-5L和15D量表的HSU均逐渐降低,表明HRQoL逐渐受损,影响老年人HRQoL的因素包括性别、年龄、高血压、受教育年限、婚姻状况、职业状态、年收入和饮酒。 展开更多
关键词 健康相关生命质量 老年人 高血压 EQ-5D-5L 15D量表
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基于自我决定理论的健康教育对肱骨远端骨折患者自我管理效能及患肢功能恢复的影响
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作者 简冬梅 吴海丽 +2 位作者 李丹 徐月圆 陶露 《护理实践与研究》 2025年第1期147-152,共6页
目的探究基于自我决定理论的健康教育对肱骨远端骨折患者自我管理效能及患肢功能恢复的影响。方法选取医院2020年1月—2023年1月收治的86例肱骨远端骨折患者为研究对象,按照组间基本资料具有可比性的原则分为对照组和观察组,各43例。对... 目的探究基于自我决定理论的健康教育对肱骨远端骨折患者自我管理效能及患肢功能恢复的影响。方法选取医院2020年1月—2023年1月收治的86例肱骨远端骨折患者为研究对象,按照组间基本资料具有可比性的原则分为对照组和观察组,各43例。对照组患者接受常规护理干预,观察组患者接受基于自我决定理论的健康教育。采用汉密顿抑郁量表(HAMD-17)、汉密顿焦虑量表(HAMA-14)评价两组患者的心理状态;采用自我效能量表(GSES)、自我护理能力测定量表(ESCA)分别评价两组患者的自我管理效能和自我护理能力;采用Mayo肘关节功能评分、健康调查简表(SF-36)分别评价两组患者的肘关节功能和生活质量。结果干预后,观察组患者HAMD-17、HAMA-14各评分均低于对照组,差异具有统计学意义(P<0.05);干预后,观察组患者GSES、ESCA、SF-36量表各维度评分均高于对照组,差异具有统计学意义(P<0.05)。结论针对肱骨远端骨折患者采用自我决定理论的健康教育方式,可改善患者心理状态,同时提高患者自我管理效能以及自我护理能力,改善患者肘关节功能以及生活质量。 展开更多
关键词 肱骨远端骨折 自我决定理论 健康教育 心理状态 自我管理效能 肘关节功能 生活质量
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