Recent Progress of Aerosol Light-scattering Enhancement Factor Studies in China

Assessment of the radiative forcing of aerosols in models still lacks sufficient input data for aerosol hygroscopicity. The light scattering enhancement factor [ f(RH, λ)] is a crucial parameter for describing aerosol hygroscopic growth properties.In this paper, we provide a survey of f(RH, λ) studies in China for the past seven years, including instrument developments of humidified nephelometers, ambient f(RH, λ) measurements in China, f(RH, λ) parameterization schemes, and f(RH, λ)applications in aerosol measurements. Comparisons of different f(RH, λ) parameterizations are carried out to check their performance in China using field measurement datasets. We also summary the parameterization schemes for predicting f(RH, λ)with aerosol chemical compositions. The recently developed methods to observe other aerosol properties using f(RH, λ)measurements, such as calculating the aerosol hygroscopicity parameter, cloud condensation nuclei number concentration,aerosol liquid water content, and aerosol asymmetry factor, are introduced. Suggestions for further research on f(RH, λ) in China are given.

Stimulated Brillouin Scattering Enhancement Factor Improvement in a 11.6-GHz-Linewidth 1.5-kW Yb-Doped Fiber Amplifier

The stimulated Brillouin scattering （SBS） threshold enhancement factor in a pure white noise linewidth broad- ening Yb-doped fiber amplifier （YDFA） with a short large mode area fiber is theoretically and experimentally studied. We demonstrate a 1064.08nm, 11.6 GHz finewidth, 1.5 k W output power YDFA with an SBS threshold enhancement of -57 （26 W SBS threshold with single frequency seed）. The output beam is near-diffraction lim- ited with a beam quality factor elM2 = 1.15 and a slope efficiency of up to 87%. No SBS or stimulated Raman scattering effects are observed in the whole power range. Further power sealing is limited by the available pump power in our system.

Enhancement Factors in Ozone Absorption Based on the Surface Renewal Model and its Application

Based on the Danckwerts surface renewal model, a simple explicit expression of the enhancement factor in ozone absorption with a first order ozone self-decomposition and parallel second order ozonation reactions has been derived. The results are compared with our previous work based on the film theory. The 2,4-dichlorophenol destruction rate by ozonation is predicted using the enhancement factor model in this paper.

CFD simulation with enhancement factor of sulfur dioxide absorption in the spray scrubber

A model describing the absorption process of SO2 into limestone slurry with a spray scrubber is presented. Both the physical performance of the spray liquid in the scrubber and the involved chemical reactions are analyzed in the model. A con- tinuous concentration change of H+ was solved by iterative coupling using Matlab, and it was found that there was a remarkable influence on the concentration of the other elements in the process of SO2 absorption. The calculations show that the enhancement factor exponentially grows with an increasing value of pH and logarithmically decays with an increasing value of the driving force. To verify the accuracy of the model, experiments were also carried out, and the results suggest that the model, after combining the physical performance of the spray and the enhancement factor, can more precisely describe SO2 absorption in a spray scrubber. Furthermore, a commercial computational fluid dynamics (CFD) tool is used to perform several simulations which describe and clarify the effects of variables on SO2 absorption. The results of numerical simulation can provide a basis for further design and optimization of the scrubber.

Factors associated with failure of enhanced recovery after surgery program in patients undergoing pancreaticoduodenectomy

Background: The enhanced recovery after surgery (ERAS) protocol is an evidence-based perioperative care program aimed at reducing surgical stress response and accelerating recovery. However, a small propor- tion of patients fail to bene t from the ERAS program following pancreaticoduodenectomy. This study aimed to identify the risk factors associated with failure of ERAS program in pancreaticoduodenectomy. Methods: Between May 2014 and December 2017, 176 patients were managed with ERAS program fol-lowing pancreaticoduodenectomy. ERAS failure was indicated by prolonged hospital stay, unplanned read- mission or unplanned reoperation. Demographics, postoperative recovery and compliance were compared of those ERAS failure groups to the ERAS success group. Results: ERAS failure occurred in 59 patients, 33 of whom had prolonged hospital stay, 18 were readmitted to hospital within 30 days after discharge, and 8 accepted reoperation. Preoperative American Society of Anesthesiologists (ASA) score of ≥III (OR = 2.736;95% CI: 1.276 6.939;P=0.028) and albumin (ALB) level of <35g/L (OR=3.589;95% CI: 1.403 9.181;P=0.008) were independent risk factors associated with prolonged hospital stay. Elderly patients (>70 years) were on a high risk of unplanned reoperation (62.5% vs. 23.1%, P=0.026). Patients with prolonged hospital stay and unplanned reoperation had delayed intake and increased intolerance of oral foods. Prolonged stay patients got off bed later than ERAS success patients did (65h vs. 46h, P =0.012). Unplanned reoperation patients tended to experience severer pain than ERAS success patients did (3 score vs. 2 score, P =0.035). Conclusions: Patients with high ASA score, low ALB level or age >70 years were at high risk of ERAS failure in pancreaticoduodenectomy. These preoperative demographic and clinical characteristics are important determinants to obtain successful postoperative recovery in ERAS program.

Role of neurotrophic factors in enhancing linear axonal growth of ganglionic sensory neurons in vitro

Neurotrophins play a major role in the regulation of neuronal growth such as neurite sprouting or regeneration in response to nerve injuries. The role of nerve growth factor, neurotrophin-3, and brain-derived neurotrophic factor in maintaining the survival of peripheral neurons remains poorly understood. In regenerative medicine, different modalities have been investigated for the delivery of growth factors to the injured neurons, in search of a suitable system for clinical applications. This study was to investigate the influence of nerve growth factor, neurotrophin-3 and brain-derived neurotrophic factor on the growth of neurites using two in vitro models of dorsal root ganglia explants and dorsal root ganglia-derived primary cell dissociated cultures. Quantitative data showed that the total neurite length and tortuosity were differently influenced by trophic factors. Nerve growth factor and, indirectly, brain-derived neurotrophic factor stimulate the tortuous growth of sensory fibers and the formation of cell clusters. Neurotrophin-3, however, enhances neurite growth in terms of length and linearity allowing for a more organized and directed axonal elongation towards a peripheral target compared to the other growth factors. These findings could be of considerable importance for any clinical application of neurotrophic factors in peripheral nerve regeneration. Ethical approval was obtained from the Regione Piemonte Animal Ethics Committee ASLTO1(file # 864/2016-PR) on September 14, 2016.

Experimental and Theoretical Studies of CO2 Absorption Enhancement by Nano-Al203 and Carbon Nanotube Particles

The influence of nano-particles on CO2absorption was studied experimentally in a stirred thermostatic reactor.Nano-Al2O3and carbon nanotube(CNT) particles which showed different hydrophobic properties were chosen for the investigation.The experimental results were compared with that of micron-size activated carbon(AC)and Al2O3particles.From the results,no enhancement by micron-size Al2O3was found,and with the increase of Al2O3concentration,the enhancement factor decreased.However,nano-Al2O3showed a weak enhancement for the CO2absorption.AC and CNT particles all intensified the gas-liquid mass transfer effectively,yet the trend of the enhancement factor with stirring speed for the two particles was different.With increasing stirring speed,the enhancement factor of AC particles was decreased,whereas in CNT suspensions it was increased.The experimental phenomena demonstrated a difference in enhancement mechanism for different size particles.For nano-particles,besides the influence of adsorbability and hydrophobicity,the micro-convection caused by Brownian motion should be also taken into account.Considering the micro-convection effect,a theoretical model was developed to shed light on the absorption enhancement by nano-particles.

Interaction between the Wilms tumour factor-1 element in the promoter of Amh and a downstream enhancer is required for a strong expression of the gene in pre-pubertal sertoli cells

Amh (anti-Müllerian hormone) is a single copy gene which is expressed strongly in Sertoli cells in the foetal testis and participates in the onset of sexual differentiation. Its promoter driving the expression of a reporter gene (d2EGFP) has been used to analyse the role of certain defined putative elements and a downstream enhancer element in gene expression. These experiments were carried out in vitro using a line of pre-pubertal mouse Sertoli cells, transienly transfected with circular DNA constructs with variously mutated promoter elements. A downstream enhancer element, situated immediately 3’ of the polyadenylation (PA) signal for Amh, has been inserted in an equivalent position in the d2EGFP construct. When the Amh promoter is unmodified, the downstream enhancer (DE) is positively associated with a large increase in EGFP expression. This is at least partly the consequence of an increased rate of expression by individual cells. Experiments using variously truncated Amh promoters indicate that an upstream region (-214 to -336) may play a minor role in facilitating enhancement. However mutation of the Wilms tumour factor-1 element, situated between the tata box and the start of translation, results in an almost complete suppression of enhancement.

Mass Transfer Enhancement of Propane Absorption into Dodecane-Water Emulsions

A one-dimensional unsteady heterogeneous parallel mass transfer(ODUHPMT) model was developed for the absorption enhancement of volatile organic compounds(VOC) by the dispersed droplets.An analytical solution for enhancement factor was obtained based on surface renewal theory and the Laplace domain transformation. The absorption rate of propane into water at different stirring speeds with the added micro dodecane droplets was investigated experimentally in a thermostatic stirred tank.The mass transfer flux across the gas-liquid interface and the enhancement factor were measured.The results showed that the dodecane has an obvious enhancement effect on propane absorption into water,the maximum enhancement factor reached 11.The enhancement factor increased with increasing dodecane volume fraction and decreased with increasing stirring speed.The experiment data agreed well with the model predictions and showed high prediction accuracy of ODUHPMT model.

Controlling factors of remaining oil distribution after water flooding and enhanced oil recovery methods for fracturecavity carbonate reservoirs in Tahe Oilfield

Based on comprehensive analysis of core, well logging, seismic and production data, the multi-scale reservoir space, reservoir types, spatial shape and distribution of fractures and caves, and the configuration relationship with production wells in fracture-cavity carbonate reservoirs were studied systematically, the influence of them on the distribution of residual oil was analyzed, and the main controlling factors mode of residual oil distribution after water flooding was established. Enhanced oil recovery methods were studied considering the development practice of Tahe oilfield. Research shows that the main controlling factors of residual oil distribution after water flooding in fracture-cavity carbonate reservoirs can be classified into four categories: local high point, insufficient well control, flow channel shielding and weak hydrodynamic. It is a systematic project to improve oil recovery in fracture-cavity carbonate reservoirs. In the stage of natural depletion, production should be well regulated to prevent bottom water channeling. In the early stage of waterflooding, injection-production relationship should be constructed according to reservoir type, connectivity and spatial location to enhance control and producing degree of waterflooding and minimize remaining oil. In the middle and late stage, according to the main controlling factors and distribution characteristics of remaining oil after water flooding, remaining oil should be tapped precisely by making use of gravity differentiation and capillary force imbibition, enhancing well control, disturbing the flow field and so on. Meanwhile, backup technologies of reservoir stimulation, new injection media, intelligent optimization etc. should be developed, smooth shift from water injection to gas injection should be ensured to maximize oil recovery.

Mass Transfer Enhancement of Gas Absorption by Adding the Dispersed Organic Phases

由增加一个驱散的器官的阶段的煤气的吸收的集体转移改进在这个工作被学习了。各种各样的驱散的器官的阶段(heptanol， octanol， isoamyl 白酒， heptane，辛烷，和异辛烷) 在实验分别地被测试。根据理论模型和试验性的数据的意见，全面容量的集体转移系数和改进因素在不同驱散的器官的阶段卷部分和激动人心的速度下面被获得。试验性的结果显示煤气液体的集体转移被增加一个驱散的器官的阶段在不同水平提高。改进的最好的表演与驱散的器官的阶段被完成 5% 并且在 670 r 慭整楲污 ? 硥楨楢? 硥散汬湥 ?敭档湡捩污瀠潲数瑲敩 s

The Enhancement of CO2 Chemical Absorption by K2CO3 Aqueous Solution in the Presence of Activated Carbon Particles

由 K2CO3/H2O 吸收剂的 CO2 的化学吸收的改进面对激活的碳(交流) ，粒子被调查。煤气的吸收评估的结果表演能面对交流粒子，和最大的改进因素显著地被提高 3.7 在低激动人心的紧张被观察。改进因素很快增加了，固体在吸收的起始的时期期间装载然后对最大的价值逐渐地变得温和。液体固体接触区域和住在煤气液体的接口的稳固的粒子的概率随粒子尺寸的增加减少了，导致集体转移的改进上的否定效果。煤气的吸收上的粒子的影响与反应率减少了。激动人心的速度变化了死液体方面上并且因而的界面的范围和集体转移率影响了在气体和液体阶段之间的集体转移；改进因素与激动人心的紧张减少了。一个异构的二地区的模型为预言改进因素被建议，计算结果与试验性的数据同意了很好。

Enhancement of CO2 Absorption under Taylor Flow in the Presence of Fine Particles

The physical absorption of CO2 in water containing different types of particles was studied in a microchannel operated under Taylor flow.The maximum enhancement factors of 1.43 2.15 were measured for activated carbon (AcC) particles.The analysis shows that the enhancement effect can be attributed to the shuttle mechanism.Considering the separate contributions of mass transfer from bubble cap and liquid film,a heterogeneous enhancement model is developed.According to this model,the enhancement factors E Cap,E Film and E Ov are mainly determined by mass transfer coefficient KL (KL,Cap and KL,Film),adsorptive capacity of particles m,and coverage fraction of particles at gas-liquid interface ζ.With both effects of particle-to-interface adhesion and apparent viscosity included,the model predicts the enhancement effect of AcC particles reasonably well.

xperimental Study of Heat Transfer Enhancement and Friction Loss Induced by Inserted Rotor-assembled Strand （I） Water

The single-phase pressure drop and heat transfer in a rotor-assembled strand inserted tube were measured using water as the working fluid.Experiment using a smooth tube was carried out to calibrate the experimental system and the data reduction method.In the experiment,fixed mounts were used to eliminate the entrance effect. The experimental results of smooth tube show that employment of fixed mounts leads to a visible bias of friction factor at relative low Reynolds numbers,although it does not significantly affect the Nusselt numbers.The measured data of inserted tube reveal that rotor-assembled strand can significantly improve heat transfer with the Nusselt number increased by 101.6%-106.6%and the overall heat transfer coefficient increased by 58.1%-67.4%within the Reynolds number range of 20000 to 36000.Meanwhile,friction factor increases by 52.2%-84.2%within the same Reynolds number range.The correlations of Nusselt number and friction factor as function of the Reynolds number and Prandtl number were determined through multivariant linear normal regression.

Experimental Study of Heat Transfer Enhancement and Friction Loss Induced by Inserted Rotor-assembled Strand （II） Lubricant Oil 22

纸通过试管描述了热转移和单相的压力落下的试验性的调查，不同装配转子的海滨作为工作液体与润滑剂在 8009000 的雷纳兹数字范围插入了。在实验，修理了山被采用消除入口效果。当它不能显著地影响 Nusselt 数字时，试验性的结果证明固定的山的雇用在 laminar 政体导致了磨擦因素的可见偏爱。为与装配转子的海滨插入的试管的实验证明为有 Nusselt 数字的热转移的显著改进在过渡政体在 laminar 政体和 125%160% 由 200%225% 增加了。同时，磨擦因素在雷纳兹数字的一样的范围以内由 200%300% 不可避免地增加了。不同装配转子的海滨的比较插入了试管，平凡试管证明热转移与一样的铅和装配转子的海滨的铅的减少一起得益于装配转子的海滨的直径的增加，磨擦因素也一样。把线性正常回归方法基于试验性的数据和彻底的 multivariant，平均 Nusselt 数字的关联和磨擦因素被建立。

Overexpression of GATA binding protein 4 and myocyte enhancer factor 2C induces differentiation of mesenchymal stem cells into cardiac-like cells

BACKGROUND Heart diseases are the primary cause of death all over the world.Following myocardial infarction,billions of cells die,resulting in a huge loss of cardiac function.Stem cell-based therapies have appeared as a new area to support heart regeneration.The transcription factors GATA binding protein 4(GATA-4)and myocyte enhancer factor 2C(MEF2C)are considered prominent factors in the development of the cardiovascular system.AIM To explore the potential of GATA-4 and MEF2C for the cardiac differentiation of human umbilical cord mesenchymal stem cells(hUC-MSCs).METHODS hUC-MSCs were characterized morphologically and immunologically by the presence of specific markers of MSCs via immunocytochemistry and flow cytometry,and by their potential to differentiate into osteocytes and adipocytes.hUC-MSCs were transfected with GATA-4,MEF2C,and their combination to direct the differentiation.Cardiac differentiation was confirmed by semiquant itative real-time polymerase chain reaction and immunocytochemistry.RESULTS hUC-MSCs expressed specific cell surface markers CD105,CD90,CD44,and vimentin but lack the expression of CD45.The transcription factors GATA-4 and MEF2C,and their combination induced differentiation in hUC-MSCs with significant expression of cardiac genes i.e.,GATA-4,MEF2C,NK2 homeobox 5(NKX2.5),MHC,and connexin-43,and cardiac proteins GATA-4,NKX2.5,cardiac troponin T,and connexin-43.CONCLUSION Transfection with GATA-4,MEF2C,and their combination effectively induces cardiac differentiation in hUC-MSCs.These genetically modified MSCs could be a promising treatment option for heart diseases in the future.

Heat Transfer Enhancement Using R1234yf Refrigerants in Micro-Ribbed Tubes in a Two-Phase Flow Regime

Experiments about heat transfer in the presence of a two-phase flow due to the condensation of a R1234yf refrigerant have been performed considering a smooth tube and two micro-fin tubes.The following experimental conditions have been considered:Condensation temperatures of 40℃,43℃ and 45℃,mass fluxes of 500–900 kg/(m^(2)·s),vapor qualities at the inlet and outlet of the heat transfer tube in the ranges 0.8–0.9 and 0.2–0.3,respectively.These tests have shown that:(1)The heat transfer coefficient increases with decreasing the condensation temperature and on increasing the mass flux;(2)The heat transfer coefficient inside the micro-fin tube is larger than that for the smooth tube;(3)The heat transfer enhancement factors for the micro-fin tube with a fin helical angle of 8°and 15°are 2.51–2.89 and 3.11–3.57,respectively;both are higher than the area increase ratio.These experimental results have been compared with correlations available in the literature:the Cavallini et al.correlation has the highest accuracy in predicting the heat transfer coefficient inside the smooth tube,the related percentage error and the average prediction error are±8%and 0.56%,respectively;for the micro-fin tube these become±25%and 6%,respectively.

Chemical Enhancement of the Surface Enhanced Raman Scattering Signals of Anilines via Their <i>Ortho</i>-Substituents

While Raman spectroscopy is a useful method for analyzing many organic compounds, it is limited by relatively low sensitivity. Therefore, Surface Enhanced Raman Spectroscopy (SERS) based on the adsorption of organic analytes onto gold or silver nanostructures has been used to enhance the signal of chemicals presented at very low concentrations. Although the plasmonic effect of SERS has been shown to play a large role in signal enhancement, the significance of the chemical effect due to the analyte chemisorption on the gold or silver surface is less well understood. In this study, the role of aniline substituents is examined by probing the SERS intensities of various anilines in silver and gold colloids using a Raman spectrometer with an excitation wavelength of 785 nm. The SERS enhancement factors and detection limits for aniline and its mono- and di-substituted ortho derivatives are determined and compared. Both the steric requirements of chemisorption and the inductive effects of electron-withdrawal due to the substituents affect the signal intensities of various vibrational modes of the amino group and the aromatic ring. The degree of enhancement is also related to the methods for preparing the silver and gold colloids, which are characterized by probing the nanoparticle morphology and its degree of aggregation using transmission electron microscopy (TEM).

Gas Absorption Enhancement of Carbon Dioxide into Ca(OH)_2 Slurries

Chemical absorption of CO2 into aqueous slurries of Ca(OH)2 was studied in a stirred thermostatic reactor. The influence of solid loading and stirring speed on absorption rate were investigated experimentally, and the results show that the enhancement factor increases with particle content due to the increase of reactive particles in the gas-liquid interfacial region. The absorption process was controlled by the diffusion of gas molecules in slurry. The influence of stirring intensity on enhancement factor is an integration of gas-liquid and liquid-solid mass transfer variation. A novel prediction model of enhancement factors was proposed with the partition of interface into two various zones, and the prediction values by the presented model are in agreement with the experimental data.