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An Investigation of Lighting Levels and Sleep Quality
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作者 Kathy Sexton-Radek Amina Mira 《Health》 2024年第9期794-800,共7页
Sleep quality in young adults is compromised. Instead of the recommended 7 hours, young adults’ schedule interruptions disturb sleep to a typical six and a half hours, with common disturbances in falling asleep and s... Sleep quality in young adults is compromised. Instead of the recommended 7 hours, young adults’ schedule interruptions disturb sleep to a typical six and a half hours, with common disturbances in falling asleep and staying asleep. Recent literature has identified an association between academic performance, negative mood state and low activity level in young adults with sleep disturbances. Young adulthood is a time for the installation of sleep health. Both individual and schedule impositions to the young adults’ sleep schedule are to be modified to obtain Sleep Health. Recent research has identified daytime light effects on sleep such as blue light from electronics as alerting and low level light for relaxation. The aim of this study was to identify sleep quality effects with varying light exposures. It was hypothesized that bright (>450 lux) light conditions would be considered focusing and low light (<220 lux) would be considered calming. We hypothesized that sleep quality would improve by 5% with the introduction of a calm light condition. Undergraduates from a small midwestern university were invited to participate in the study in exchange for a gift card. Six participants completed the study, two males, four females all between 21 - 24 years old. Both hypotheses were supported by qualitative analysis. 展开更多
关键词 LIGHT Sleep Quality lighting Sleep Disturbance
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Analysis of Current Research and Future Development Trends of Applying Solar Energy in Street Lighting
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作者 Liyan Zhang Qingying Zhou +1 位作者 Yueming Zhan Hu Guo 《Journal of Electronic Research and Application》 2024年第3期191-197,共7页
In the context of promoting green energy transition and addressing climate change globally,solar energy,as a clean and renewable energy source,has gradually become a hot topic for research.Solar streetlight systems re... In the context of promoting green energy transition and addressing climate change globally,solar energy,as a clean and renewable energy source,has gradually become a hot topic for research.Solar streetlight systems realize energy self-sufficiency and environment-friendly lighting by integrating photovoltaic power generation technology and efficient LED lighting technology.By comprehensively analyzing the current status of the application of solar streetlights at home and abroad,this paper discusses its technical advantages,market penetration,and challenges in its development.In terms of technical characteristics,this paper focuses on analyzing the key technologies such as energy conversion efficiency and intelligent control systems of solar streetlights. 展开更多
关键词 Solar streetlights Green energy Photovoltaic power generation LED lighting Intelligent control system
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Application Strategies of Automatic Addressable Single-Lamp Control Technology in Tunnel Lighting
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作者 Huiyan Yang 《Journal of World Architecture》 2024年第2期90-95,共6页
The article mainly studies the application strategy of automatic addressable single-lamp control technology in tunnel lighting.It encompasses an introduction to this technology,an analysis of the tunnel lighting syste... The article mainly studies the application strategy of automatic addressable single-lamp control technology in tunnel lighting.It encompasses an introduction to this technology,an analysis of the tunnel lighting system using automatic addressable single-lamp control technology,and outlines the main development direction for this technology in modern tunnel lighting.The aim is to offer insights that can inform the rational deployment of this technology,thereby enhancing the lighting control effectiveness in modern tunnels and meeting their specific lighting requirements more effectively. 展开更多
关键词 Tunnel lighting Automatic addressable single-lamp control technology System design Cascade control
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Application of Intelligent Technology in Building Electrical Lighting Project
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作者 Yingling Dai Qinghua Zhao 《Journal of Electronic Research and Application》 2024年第3期112-117,共6页
The rapid development of intelligent technology has led to its introduction into the field of electrical lighting in buildings.It provides more technical support for system design,use,and management,and creates a comf... The rapid development of intelligent technology has led to its introduction into the field of electrical lighting in buildings.It provides more technical support for system design,use,and management,and creates a comfortable and safe living environment.The adoption of intelligent technology enables the creation of an intelligent management system,where controllers and sensors are used to adjust the light source within the building,monitor and manage the lighting system in real time,monitor the energy consumption and safety of the system,and achieve the goal of energy saving and emission reduction.This paper briefly discusses the application and significance of intelligent technology in electrical lighting and puts forward design ideas to optimize electrical lighting and measures for lighting system management. 展开更多
关键词 Intelligent technology BUILDINGS Electric lighting
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The Application of Intelligent Lighting in Thermal Power Plants
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作者 Xiaozhong Kang Shuangqiang Liu +1 位作者 Guoqing Hu Haibin Huang 《Journal of Electronic Research and Application》 2024年第4期180-185,共6页
With the rapid development of electronic information technology,the Internet of Things(IoT),Internet technology,and modern communication technology,people are demanding higher standards for the building environment.Es... With the rapid development of electronic information technology,the Internet of Things(IoT),Internet technology,and modern communication technology,people are demanding higher standards for the building environment.Especially in modern large-scale buildings with high levels of industrialization,lighting systems should also be optimized accordingly.This article explores the application path of intelligent lighting in thermal power plants for reference. 展开更多
关键词 Intelligent lighting Thermal power plants Application path
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Application of Smart Streetlights in Urban Road Lighting
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作者 Huiyan Yang 《Journal of Electronic Research and Application》 2024年第3期83-88,共6页
The construction and installation of street lighting is an important element in the modernization of China’s cities.Besides,it also plays an important role in raising the living standards of the people.In recent year... The construction and installation of street lighting is an important element in the modernization of China’s cities.Besides,it also plays an important role in raising the living standards of the people.In recent years,with the technological and economic development,smart street lighting has gradually emerged.Key functions of smart street lighting include road illumination,cultural promotion,meteorological monitoring,public broadcasting,and 5G micro-base stations.The overall quality of smart street lighting construction directly impacts the effectiveness of urban development and the city’s comprehensive growth.This paper analyzes the concept of smart street lighting,its advantages and disadvantages,the functionalities of smart street light systems,and the application of smart street lighting in urban road illumination. 展开更多
关键词 Smart streetlights Urban street lighting LED streetlights
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Application of Landscape Smart Lighting in Construction Projects
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作者 Yingling Dai Qinghua Zhao 《Journal of World Architecture》 2024年第2期78-83,共6页
Currently,to effectively construct high-quality smart cities and achieve comprehensive governance goals,various industries must embrace the transformation and upgrading of traditional management methods through the in... Currently,to effectively construct high-quality smart cities and achieve comprehensive governance goals,various industries must embrace the transformation and upgrading of traditional management methods through the integration of new technologies.Among these,landscape smart lighting serves as a crucial tool for advancing smart city development.By judiciously applying this technology,it is possible to enhance traditional lighting methods and offer people novel experiences in their daily lives.Recognizing this importance,this article analyzes and organizes the content of landscape smart lighting,delves into its system characteristics,and summarizes its principles and practices in the field of architectural engineering as practical references for application scenarios. 展开更多
关键词 Landscape smart lighting Smart city Construction engineering
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Strategies for Applying LED Lights in Night Space Lighting for Bridges
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作者 Yingling Dai Qinghua Zhao 《Journal of World Architecture》 2024年第3期57-62,共6页
LED lights have been widely used in urban night space lighting in recent years as they are small,energy-saving,and efficient.This article explores the use of LEDs in bridge night space lighting and their application s... LED lights have been widely used in urban night space lighting in recent years as they are small,energy-saving,and efficient.This article explores the use of LEDs in bridge night space lighting and their application strategies.The aim is to offer valuable insights and references for urban planners and bridge lighting designers in China.By advancing the application of LED technology in bridge night lighting,the goal is to enhance the city’s nighttime ambiance,making the bridge an iconic landmark and a defining feature of the city. 展开更多
关键词 Bridge night space lighting LED application Color band and gradient Artistic value Online publication:July 11 2024
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Short-term night lighting disrupts lipid and glucose metabolism in Zebra Finches:Implication for urban stopover birds
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作者 Na Zhu Jing Shang Shuping Zhang 《Avian Research》 SCIE CSCD 2023年第4期663-670,共8页
Night lighting has been shown to affect wild animals.To date,the effects of night lighting on the metabolic homeostasis of birds that spend short time in urban environments remain unclear.Using model bird species Zebr... Night lighting has been shown to affect wild animals.To date,the effects of night lighting on the metabolic homeostasis of birds that spend short time in urban environments remain unclear.Using model bird species Zebra Finch(Taeniopygia guttata),we investigated the effects of short-term night lighting on liver transcriptome,blood glucose,triglyceride,and thyroxine(T4 and T3)levels in birds exposed to two different night lighting duration periods(three days and six days).After three days of night lighting exposure,the expression of genes involved in fat synthesis in the liver was upregulated while the expression of genes involved in fatty acid oxidation and triglyceride decomposition was downregulated.There was also a reduction in blood triglyceride,glucose,and T3 concentrations.However,after six days of night lighting,the expression of genes associated with fatty acid decomposition and hyperglycemia in the liver was upregulated,while the expression of genes involved in fat synthesis was downregulated.Simultaneously,blood glucose levels and T3 concentration increased.These findings indicate that short-term exposure to night lighting can disrupt the lipid and glucose metabolism of small passerine birds,and longer stopovers in urban area with intense night lighting may cause birds to consume more lipid energy. 展开更多
关键词 BIRDS Glucose LIPID Metabolism Night lighting SHORT-TERM
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Intelligent System Application to Monitor the Smart City Building Lighting
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作者 Tzu-Chia Chen Ngakan Ketut Acwin Dwijendra +2 位作者 Saurabh Singhal R.Sivaraman Amr Mamdouh 《Computers, Materials & Continua》 SCIE EI 2023年第5期3159-3169,共11页
A smart city incorporates infrastructure methods that are environmentally responsible,such as smart communications,smart grids,smart energy,and smart buildings.The city administration has prioritized the use of cuttin... A smart city incorporates infrastructure methods that are environmentally responsible,such as smart communications,smart grids,smart energy,and smart buildings.The city administration has prioritized the use of cutting-edge technology and informatics as the primary strategy for enhancing service quality,with energy resources taking precedence.To achieve optimal energy management in themultidimensional system of a city tribe,it is necessary not only to identify and study the vast majority of energy elements,but also to define their implicit interdependencies.This is because optimal energy management is required to reach this objective.The lighting index is an essential consideration when evaluating the comfort indicators.In order to realize the concept of a smart city,the primary objective of this research is to create a system for managing and monitoring the lighting index.It is possible to identify two distinct phaseswithin the intelligent system.Once data collection concludes,the monitoring system will be activated.In the second step,the operation of the control system is analyzed and its effect on the performance of the numerical model is determined.This evaluation is based on the proposed methodology.The optimized resultswere deemed satisfactory because they maintained the brightness index value(79%)while consuming less energy.The intelligent implementation system generated satisfactory outcomes,which were observed 1.75 times on average. 展开更多
关键词 Smart city lighting index residential building energy consumption
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Effects of Variable Lighting Intensity on Growth Characteristics and Nutritional Quality of Hydroponically Grown Arugula(Eruca sativa Mill.)
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作者 Sun Ming-han Zhou Fu-jun +1 位作者 Liu He Zhao Jing 《Journal of Northeast Agricultural University(English Edition)》 CAS 2023年第1期85-96,共12页
Arugula(Eruca sativa Mill.),as an edible medicinal vegetable of peculiar flavor,is served as uncooked dish.The influence of variable lighting intensity(LI)on the growth characteristics and nutritional quality of hydro... Arugula(Eruca sativa Mill.),as an edible medicinal vegetable of peculiar flavor,is served as uncooked dish.The influence of variable lighting intensity(LI)on the growth characteristics and nutritional quality of hydroponically grown arugula was investigated by using light-emitting diodes(LEDs)to light the hydroponically grown arugula for a reference for industrialized arugula production.The dynamic demands of arugula for LI in the seedling stage,initial growth stage and vigorous growth stage were tested under two light quality conditions including a red/blue light ratio of 7:1 and a light/dark photoperiod of 12 h/12 h.Then,the curves of variable LI-induced changes in the growth indices of arugula in different development periods were drawn.Next,the influence of variable LI on the growth characteristics and nutritional quality of arugula was investigated by measuring the dry/fresh weight ratio,chlorophyll content,vitamin C content and soluble protein content.Variable LI significantly increased the height,stem diameter,leaf width,dry/fresh weight ratio,chlorophyll content and soluble protein content of arugula plant.Plant height,stem diameter,dry/fresh weight ratio,chlorophyll content and soluble protein content were the highest in the group exposed to LI of 200,300 and 300μmol•m^(-2)•s^(-1)during the seedling stage,initial growth stage and vigorous growth stage,respectively.The greatest leaf width was achieved at LI of 100,250 and 350μmol•m^(-2)•s^(-1),respectively.High intensity LI markedly repressed the synthesis of vitamin C. 展开更多
关键词 arugula LED lighting intensity growth characteristics nutritional quality plant factory
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Controlled LED Lighting for Horticulture: A Review
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作者 Emmanouil D. Fylladitakis 《Open Journal of Applied Sciences》 CAS 2023年第2期175-188,共14页
As energy gradually becomes a more valuable commodity, the desire for reduced energy losses strengthens. Lighting is a critical field on this matter, as it accounts for a large percentage of the global electricity con... As energy gradually becomes a more valuable commodity, the desire for reduced energy losses strengthens. Lighting is a critical field on this matter, as it accounts for a large percentage of the global electricity consumption and modern lighting systems are greatly more efficient than incandescent, discharge, and fluorescent lights. Previous research has proven that plants do not require the entire visible spectrum but react only to specific wavelengths, making it possible to control their growth and yield via artificial lighting. The flexibility of control of Light Emitting Diode (LED) lights allows for the combination of great energy losses reduction and controlled plant growth, achieving the improvement of two major parameters in a single action. This review paper summarizes the current research on the effect different light wavelengths have on specific plant species and discusses the applications of LED lighting for horticulture, yield storage, and disease protection. 展开更多
关键词 Horticulture lighting Agriculture lighting Controlled LED Light Light Wavelength Effects Light Spectrum VEGETABLES CROPS PHOTORECEPTORS
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Research on the Application of Green Lighting Technology in Sports Lighting
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作者 Lizhi Liu Jingshuo Huang Xuanmin Zhu 《Journal of Environmental Protection》 2023年第10期781-788,共8页
With China’s continued development of society and economy, the importance of ecological environmental protection is growing. This protection has become an indispensable part of social development. The use of various ... With China’s continued development of society and economy, the importance of ecological environmental protection is growing. This protection has become an indispensable part of social development. The use of various green environmental protection equipment can effectively promote ecological environmental protection and reduce the adverse effects of human activities on the environment. In the field of sports lighting equipment in China, traditional lighting methods constitute an inherent danger to the environment, leading to a waste of valuable resources and environmental pollution. This study involves a multi-tile-multifunctional-function controller, which effectively solves the control problem of the control light. In the sports lighting group, the high and low-level lighting of the sports lighting group, and adjust the light from the height highly effectively to adjust each height. The low-shot mode reduces the power consumption of the system by about 33% to 60%, which significantly helps energy saving. By optimizing the performance of the lighting system, promoting the preservation of power resources, reducing the adverse effects of pollution caused by equipment utilization and energy waste, and promoting the harmonious cohabitation of human and natural environment. . 展开更多
关键词 Parameters of Metal Z-Shaped Single-Ended Light Source Green lighting Practices Sports lighting System Lamp Model
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Application Strategy of PLC Technology in Energy-Saving Control of Tunnel Lighting
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作者 Yuling Zhang 《Journal of Electronic Research and Application》 2023年第3期7-12,共6页
In this study,we investigated on the application of planar lightwave circuit(PLC)technology in energy-saving control of tunnel lighting.The application status of PLC in the field of energy saving followed by the neces... In this study,we investigated on the application of planar lightwave circuit(PLC)technology in energy-saving control of tunnel lighting.The application status of PLC in the field of energy saving followed by the necessity of energy saving in tunnel lighting was analyzed.Finally,the application of PLC in tunnel lighting energy-saving control around the three dimensions of system overall architecture design,control scheme,and program control process was investigated.The results showed that the system meets the requirements of control effect,robustness,and visual effect after trial operation,and is suitable for practical applications. 展开更多
关键词 Energy-saving tunnel lighting PLC technology Control scheme Program control
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人LIGHT和HSV-TK-EGFP基因共转染的MSCs抗肿瘤免疫的体内研究
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作者 陈芬 江千秋 +1 位作者 焦兰 唐澍 《实用癌症杂志》 2024年第11期1744-1748,共5页
目的研究与单纯疱疹病毒的糖蛋白D竞争结合单纯疱疹病毒进入介导物(herpes virus entry mediator,HVEM)的淋巴毒素类似物(homologous to lymphotoxins,exhibits inducible expression,and competes with HSV glycoprotein D for HVEM,a ... 目的研究与单纯疱疹病毒的糖蛋白D竞争结合单纯疱疹病毒进入介导物(herpes virus entry mediator,HVEM)的淋巴毒素类似物(homologous to lymphotoxins,exhibits inducible expression,and competes with HSV glycoprotein D for HVEM,a receptor expressed by T lymphocytes,LIGHT)基因和单纯疱疹病毒胸苷激酶(herpes simplex virus thymidine kinase,HSV-TK)基因共转染的骨髓间充质干细胞(mesenchymal stem cells,MSCs)在体内的抗肿瘤免疫功能。方法将pIRES2-LIGHT基因和HSV-TK-EGFP基因共转染小鼠骨髓间充质干细胞(MSCs/LT组),以转染空载体和转染HSV-TK-EGFP基因的骨髓间充质干细胞作对照。流式细胞仪检测LIGHT分子和HSV-TK-EGFP分子在稳定转染的骨髓间充质干细胞上的表达。体内迁移实验观察MSCs/LT在小鼠体内迁移情况。观察更昔洛韦注射前后MSCs/LT对荷瘤小鼠体内肿瘤的治疗作用。ELISA法检测小鼠肿瘤组织中IFN-γ,IL-2和IL-10的水平。结果流式细胞仪检测发现,MSCs/LT能稳定高表达LIGHT分子。MSCs/LT有特异地向肿瘤组织趋化的特性。MSCs/LT和MSCs/T有较好的抑制肿瘤生长的能力,但在更昔洛韦诱导后,MSCs/LT的抗肿瘤效应下降甚至消失。同时,MSCs/LT可促使T细胞进入肿瘤组织,并促进T细胞分泌IL-2、IFN-γ,抑制IL-10分泌(P<0.05)。结论共转染人LIGHT和HSV-TK-EGFP基因的骨髓间充质干细胞能稳定高表达LIGHT分子,能特异性地向荷瘤小鼠体内肿瘤组织趋化并抑制肿瘤的生长,这种体内抗肿瘤功能可能与促进T淋巴细胞IL-2、IFN-γ等细胞因子的分泌,改善局部免疫抑制环境有关。 展开更多
关键词 抗肿瘤免疫 间充质干细胞 转染 LIGHT基因 HSV-TK-EGFP基因
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Effects of thinning on the understory light environment of different stands and the photosynthetic performance and growth of the reforestation species Phoebe bournei 被引量:2
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作者 Shicheng Su Nianqing Jin Xiaoli Wei 《Journal of Forestry Research》 SCIE EI CAS CSCD 2024年第1期12-28,共17页
Light levels determine regeneration in stands and a key concern is how to regulate the light environment of different stand types to the requirements of the understory.In this study,we selected three stands typical in... Light levels determine regeneration in stands and a key concern is how to regulate the light environment of different stand types to the requirements of the understory.In this study,we selected three stands typical in south China(a Cryptomeria japonica plantation,a Quercus acutissima plantation,and a mixed stand of both)and three thinning intensities to determine the best understory light environ-ment for 3-year-old Phoebe bournei seedlings.The canopy structure,understory light environment,and photosynthe-sis and growth indicators were assessed following thin-ning.Thinning improved canopy structure and understory light availability of each stand;species composition was the reason for differences in the understory light environ-ment.Under the same thinning intensity,the mixed stand had the greatest light radiation and most balanced spectral composition.P.bournei photosynthesis and growth were closely related to the light environment;all three stands required heavy thinning to create an effective and sustained understory light environment.In a suitable understory light environment,the efficiency of light interception,absorption,and use by seedlings was enhanced,resulting in a higher carbon assimilation the main limiting factor was stomatal conductance.As a shade-avoidance signal,red/far-red radia-tion is a critical factor driving changes in photosynthesis and growth of P.bournei seedlings,and a reduction increased light absorption and use capacity and height:diameter ratios.The growth advantage transformed from diameter to height,enabling seedlings to access more light.Our findings suggest that the regeneration of shade-tolerant species such as P.bournei could be enhanced if a targeted approach to thinning based on stand type was adopted. 展开更多
关键词 THINNING Understory light environment Phoebe bournei Photosynthetic performance Growth performance
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240 nm AlGaN-based deep ultraviolet micro-LEDs:size effect versus edge effect 被引量:2
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作者 Shunpeng Lu Jiangxiao Bai +6 位作者 Hongbo Li Ke Jiang Jianwei Ben Shanli Zhang Zi-Hui Zhang Xiaojuan Sun Dabing Li 《Journal of Semiconductors》 EI CAS CSCD 2024年第1期55-62,共8页
240 nm AlGaN-based micro-LEDs with different sizes are designed and fabricated.Then,the external quantum efficiency(EQE)and light extraction efficiency(LEE)are systematically investigated by comparing size and edge ef... 240 nm AlGaN-based micro-LEDs with different sizes are designed and fabricated.Then,the external quantum efficiency(EQE)and light extraction efficiency(LEE)are systematically investigated by comparing size and edge effects.Here,it is revealed that the peak optical output power increases by 81.83%with the size shrinking from 50.0 to 25.0μm.Thereinto,the LEE increases by 26.21%and the LEE enhancement mainly comes from the sidewall light extraction.Most notably,transversemagnetic(TM)mode light intensifies faster as the size shrinks due to the tilted mesa side-wall and Al reflector design.However,when it turns to 12.5μm sized micro-LEDs,the output power is lower than 25.0μm sized ones.The underlying mechanism is that even though protected by SiO2 passivation,the edge effect which leads to current leakage and Shockley-Read-Hall(SRH)recombination deteriorates rapidly with the size further shrinking.Moreover,the ratio of the p-contact area to mesa area is much lower,which deteriorates the p-type current spreading at the mesa edge.These findings show a role of thumb for the design of high efficiency micro-LEDs with wavelength below 250 nm,which will pave the way for wide applications of deep ultraviolet(DUV)micro-LEDs. 展开更多
关键词 ALGAN deep ultraviolet micro-LEDs light extraction efficiency size effect edge effect
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Association of accelerometer-measured sleep duration and different intensities of physical activity with incident type 2 diabetes in a population-based cohort study 被引量:2
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作者 Xinyi Jin Yilin Chen +8 位作者 Hongliang Feng Mingqing Zhou Joey W.Y.Chang Yaping Liu Alice Pik Shan Kong Xiao Tan Yun-Kwok Wing Yannis Yan Liang Jihui Zhang 《Journal of Sport and Health Science》 SCIE CAS CSCD 2024年第2期222-232,共11页
Purpose:The aim of the current study was to investigate the association of accelerometer-measured sleep duration and different intensities of physical activity(PA)with the risk of incident type 2 diabetes in a populat... Purpose:The aim of the current study was to investigate the association of accelerometer-measured sleep duration and different intensities of physical activity(PA)with the risk of incident type 2 diabetes in a population-based prospective cohort study.Methods:Altogether,88,000 participants(mean age=62.2±7.9 years,mean±SD)were included from the UK Biobank.Sleep duration(short:<6 h/day;normal:6-8 h/day;long:>8 h/day)and PA of different intensities were measured using a wrist-won accelerometer over a 7-day period between 2013 and 2015.PA was classified according to the median or World Health Organization-recommendation:total volume of PA(high,low),moderate-to-vigorous PA(MVPA)(recommended,not recommended),and light-intensity PA(high,low).Incidence of type 2diabetes was ascertained using hospital records or death registries.Results:During a median follow-up of 7.0 years,1615 incident type 2 diabetes cases were documented.Compared with normal sleep duration,short(hazard ratio(HR)=1.21,95%confidence interval(95%CI):1.03-1.41)but not long sleep duration(HR=1.01,95%CI:0.89-1.15)was associated with excessive type 2 diabetes risk.This increased risk among short sleepers seems to be protected against by PA.Compared with normal sleepers with high or recommended PA,short sleepers with low volume of PA(HR=1.81,95%CI:1.46-2.25),not recommended(below the World Health Organization-recommended level of)MVPA(HR=1.92,95%CI:1.55-2.36),or low light-intensity PA(HR=1.49,95%CI:1.13-1.90)had a higher risk of type 2 diabetes,while short sleepers with a high volume of PA(HR=1.14,95%CI:0.88-1.49),recommended MVPA(HR=1.02,95%CI:0.71-1.48),or high light-intensity PA(HR=1.14,95%CI:0.92-1.41)did not.Conclusion:Accelerometer-measured short but not long sleep duration was associated with a higher risk of incident type 2 diabetes.A higher level of PA,regardless of intensity,potentially ameliorates this excessive risk. 展开更多
关键词 Light physical activity Sleep duration Triaxial accelerometer Type 2 diabetes UK Biobank
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A novel mechanism of PHB2-mediated mitophagy participating in the development of Parkinson's disease 被引量:3
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作者 Yongjiang Zhang Shiyi Yin +4 位作者 Run Song Xiaoyi Lai Mengmeng Shen Jiannan Wu Junqiang Yan 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第8期1828-1834,共7页
Endoplasmic reticulum stress and mitochondrial dysfunction play important roles in Parkinson s disease,but the regulato ry mechanism remains elusive.Prohibitin-2(PHB2)is a newly discove red autophagy receptor in the m... Endoplasmic reticulum stress and mitochondrial dysfunction play important roles in Parkinson s disease,but the regulato ry mechanism remains elusive.Prohibitin-2(PHB2)is a newly discove red autophagy receptor in the mitochondrial inner membrane,and its role in Parkinson’s disease remains unclear.Protein kinase R(PKR)-like endoplasmic reticulum kinase(PERK)is a factor that regulates cell fate during endoplasmic reticulum stress.Parkin is regulated by PERK and is a target of the unfolded protein response.It is unclear whether PERK regulates PHB2-mediated mitophagy thro ugh Parkin.In this study,we established a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine(MPTP)-induced mouse model of Parkinson’s disease.We used adeno-associated virus to knockdown PHB2 expression.Our res ults showed that loss of dopaminergic neurons and motor deficits were aggravated in the MPTP-induced mouse model of Parkinson’s disease.Ove rexpression of PHB2 inhibited these abnormalities.We also established a 1-methyl-4-phenylpyridine(MPP+)-induced SH-SY5Y cell model of Parkinson’s disease.We found that ove rexpression of Parkin increased co-localization of PHB2 and microtubule-associated protein 1 light chain 3,and promoted mitophagy.In addition,MPP+regulated Parkin involvement in PHB2-mediated mitophagy through phosphorylation of PERK.These findings suggest that PHB2 participates in the development of Parkinson’s disease by intera cting with endoplasmic reticulum stress and Parkin. 展开更多
关键词 endoplasmic reticulum dopaminergic neuron microtubule-associated protein 1 light chain 3 MITOPHAGY oxidative stress PARKIN Parkinson’s disease PKR-like endoplasmic reticulum kinase reactive oxygen species prohibitin-2
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Cu/TiO_(2) Photocatalysts for CO_(2) Reduction: Structure and Evolution of the Cocatalyst Active Form 被引量:2
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作者 Andrey A.Saraev Anna Yu.Kurenkova +3 位作者 Denis D.Mishchenko Alexandr L.Trigub Evgeniy Yu.Gerasimov Ekaterina A.Kozlova 《Transactions of Tianjin University》 EI CAS 2024年第2期140-151,共12页
Extensive work on a Cu-modified TiO_(2) photocatalyst for CO_(2) reduction under visible light irradiation was conducted. The structure of the copper cocatalyst was established using UV-vis diff use refl ectance spect... Extensive work on a Cu-modified TiO_(2) photocatalyst for CO_(2) reduction under visible light irradiation was conducted. The structure of the copper cocatalyst was established using UV-vis diff use refl ectance spectroscopy, high-resolution transmis- sion electron microscopy, X-ray absorption spectroscopy, and X-ray photoelectron spectroscopy. It was found that copper exists in different states (Cu 0 , Cu^(+) , and Cu^(2+) ), the content of which depends on the TiO_(2) calcination temperature and copper loading. The optimum composition of the cocatalyst has a photocatalyst based on TiO_(2) calcined at 700℃ and modified with 5 wt% copper, the activity of which is 22 μmol/(h·g cat ) (409 nm). Analysis of the photocatalysts after the photocatalytic reaction disclosed that the copper metal on the surface of the calcined TiO_(2) was gradually converted into Cu_(2) O during the photocatalytic reaction. Meanwhile, the metallic copper on the surface of the noncalcined TiO_(2) did not undergo any trans- formation during the reaction. 展开更多
关键词 PHOTOCATALYSIS Photocatalytic CO_(2)conversion Visible light Titanium dioxide Copper Copper oxides Methane formation Photocatalyst transformation
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