BACKGROUND Limb body wall complex(LBWC)is a fatal malformation characterized by major defects in the fetal abdominal or thoracic wall,visceral herniation,significant scoliosis or spina bifida,limb deformities,craniofa...BACKGROUND Limb body wall complex(LBWC)is a fatal malformation characterized by major defects in the fetal abdominal or thoracic wall,visceral herniation,significant scoliosis or spina bifida,limb deformities,craniofacial deformities,and umbilical cord abnormalities(short or absent umbilical cord).Early diagnosis of this condition is of great clinical significance for clinical intervention and pregnancy decision-making.With the rapid development of fetal ultrasound medicine,early pregnancy(11-13+6 wk)standardized prenatal ultrasound examinations have been widely promoted and applied.AIM To explore the value of prenatal ultrasound in the diagnosis of fetal LBWC syndrome during early pregnancy.METHODS The ultrasonographic data and follow-up results of 18 cases of fetal LBWC diagnosed by prenatal ultrasound during early pregnancy(11-13+6 wk)were retrospectively analyzed,and their ultrasonographic characteristics were analyzed.RESULTS Among the 18 fetuses with limb wall abnormalities,there were spinal dysplasia(18/18,100%),varying degrees of thoracoschisis and gastroschisis(18/18,100%),limb dysplasia in 6 cases(6/18,33%),craniocerebral malformations in 4 cases(4/18,22%),thickening of the transparent layer of the neck in 5 cases(5/18,28%),and umbilical cord abnormalities in 18 cases(18/18,100%),single umbilical artery in 5 cases.CONCLUSION Prenatal ultrasound in early pregnancy can detect LBWC as early as possible,and correct prenatal evaluation provides important guidance value for pregnancy decision-making and early intervention.展开更多
为研究真实工况下人员在爆炸冲击波作用下的动态响应特性,开展某型云爆弹静爆作用下工事内仿人形装置(Anthropomorphic Test Device,ATD)和绵羊的毁伤试验研究。采用爆炸测试装置和简易假人作为研究对象,通过6发爆炸试验分析爆炸冲击波...为研究真实工况下人员在爆炸冲击波作用下的动态响应特性,开展某型云爆弹静爆作用下工事内仿人形装置(Anthropomorphic Test Device,ATD)和绵羊的毁伤试验研究。采用爆炸测试装置和简易假人作为研究对象,通过6发爆炸试验分析爆炸冲击波在ATD表面传播规律,开展2种人员损伤预测模型的对比分析。研究结果表明:在本试验工况下,冲击波和崩落的混凝土碎块是主要的毁伤元;爆炸冲击波在ATD表面首先发生反射,随后绕射至其他部位,压力曲线表现出非典型冲击波特征,反射叠加效应明显;在典型冲击波特征正压作用时间区间内,由于Axelsson损伤模型线性阻尼项的影响,求解的胸壁运动速度呈现出先增大至峰值后降低的现象;Axelsson损伤模型与UFC 3-340-02规范相比,在人员损伤预测方面相对保守。所得研究结果可为工程应用及毁伤评估提供参考。展开更多
文摘BACKGROUND Limb body wall complex(LBWC)is a fatal malformation characterized by major defects in the fetal abdominal or thoracic wall,visceral herniation,significant scoliosis or spina bifida,limb deformities,craniofacial deformities,and umbilical cord abnormalities(short or absent umbilical cord).Early diagnosis of this condition is of great clinical significance for clinical intervention and pregnancy decision-making.With the rapid development of fetal ultrasound medicine,early pregnancy(11-13+6 wk)standardized prenatal ultrasound examinations have been widely promoted and applied.AIM To explore the value of prenatal ultrasound in the diagnosis of fetal LBWC syndrome during early pregnancy.METHODS The ultrasonographic data and follow-up results of 18 cases of fetal LBWC diagnosed by prenatal ultrasound during early pregnancy(11-13+6 wk)were retrospectively analyzed,and their ultrasonographic characteristics were analyzed.RESULTS Among the 18 fetuses with limb wall abnormalities,there were spinal dysplasia(18/18,100%),varying degrees of thoracoschisis and gastroschisis(18/18,100%),limb dysplasia in 6 cases(6/18,33%),craniocerebral malformations in 4 cases(4/18,22%),thickening of the transparent layer of the neck in 5 cases(5/18,28%),and umbilical cord abnormalities in 18 cases(18/18,100%),single umbilical artery in 5 cases.CONCLUSION Prenatal ultrasound in early pregnancy can detect LBWC as early as possible,and correct prenatal evaluation provides important guidance value for pregnancy decision-making and early intervention.
文摘为研究真实工况下人员在爆炸冲击波作用下的动态响应特性,开展某型云爆弹静爆作用下工事内仿人形装置(Anthropomorphic Test Device,ATD)和绵羊的毁伤试验研究。采用爆炸测试装置和简易假人作为研究对象,通过6发爆炸试验分析爆炸冲击波在ATD表面传播规律,开展2种人员损伤预测模型的对比分析。研究结果表明:在本试验工况下,冲击波和崩落的混凝土碎块是主要的毁伤元;爆炸冲击波在ATD表面首先发生反射,随后绕射至其他部位,压力曲线表现出非典型冲击波特征,反射叠加效应明显;在典型冲击波特征正压作用时间区间内,由于Axelsson损伤模型线性阻尼项的影响,求解的胸壁运动速度呈现出先增大至峰值后降低的现象;Axelsson损伤模型与UFC 3-340-02规范相比,在人员损伤预测方面相对保守。所得研究结果可为工程应用及毁伤评估提供参考。
