A 1.34 GHz-1=60 MHz low noise amplifier (LNA) designed in a 0.35 pm SiGe process is presented. The designed LNA exhibits a power gain of 21.46 dB and a noise figure (NF) of 1.27 dB at 1.34 GHz. The linearity is im...A 1.34 GHz-1=60 MHz low noise amplifier (LNA) designed in a 0.35 pm SiGe process is presented. The designed LNA exhibits a power gain of 21.46 dB and a noise figure (NF) of 1.27 dB at 1.34 GHz. The linearity is improved with an active biasing technique. The post-layout simulation shows an input referred 1-dB compression point (IPldn) of-11.52 dBm. Compared with the recent reported high gain LNAs, the proposed LNA has a much better linearity without degrading other performance. The LNA draws 10 mA current from a 3.3 V power supply.展开更多
A typical biological cell lives in a small volmne at room temperature; the noise effect on the cell signal transduction pathway may play an important role in its dynamics. Here, using the transforming growth factor-β...A typical biological cell lives in a small volmne at room temperature; the noise effect on the cell signal transduction pathway may play an important role in its dynamics. Here, using the transforming growth factor-β signal transduction pathway as an example, we report our stochastic simulations of the dynamics of the pathway and introduce a linear noise approximation method to calculate the transient intrinsic noise of pathway components. We compare the numerical solutions of the linear noise approximation with the statistic results of chemical Langevin equations, and find that they are quantitatively in agreement with the other. When transforming growth factor-β dose decreases to a low level, the time evolution of noise fluctuation of nuclear Smad2-Smad4 complex indicates the abnormal enhancement in the transient signal activation process.展开更多
Feed-forward gene transcriptional regulatory networks, as a set of common signal motifs, are widely distributed in the biological systems. In this paper, the noise characteristics and propagation mechanism of various ...Feed-forward gene transcriptional regulatory networks, as a set of common signal motifs, are widely distributed in the biological systems. In this paper, the noise characteristics and propagation mechanism of various feed-forward gene transcriptional regulatory loops are investigated, including (i) coherent feed-forward loops with AND-gate, (ii) coherent feed-forward loops with OR-gate logic, and (iii) incoherent feed-forward loops with AND-gate logic. By introducing logarithmic gain coefficient and using linear noise approximation, the theoretical formulas of noise decomposition are derived and the theoretical results are verified by Gillespie simulation. From the theoretical and numerical results of noise decomposition algorithm, three general characteristics about noise transmission in these different kinds of feed-forward loops are observed, i) The two-step noise propagation of upstream factor is negative in the incoherent feed-forward loops with AND-gate logic, that is, upstream factor can indirectly suppress the noise of downstream factors, ii) The one-step propagation noise of upstream factor is non-monotonic in the coherent feed-forward loops with OR-gate logic, iii) When the branch of the feed-forward loop is negatively controlled, the total noise of the downstream factor monotonically increases for each of all feed-forward loops. These findings are robust to variations of model parameters. These observations reveal the universal rules of noise propagation in the feed-forward loops, and may contribute to our understanding of design principle of gene circuits.展开更多
A new architecture of CMOS low voltage downconve rsion mixer is presented.With 1.452GHz LO input and 1.45GHz RF input,simulation results show that the conversion gain is 15dB,IIP3 is -4.5dBm,NF is 17dB,the maximum tra...A new architecture of CMOS low voltage downconve rsion mixer is presented.With 1.452GHz LO input and 1.45GHz RF input,simulation results show that the conversion gain is 15dB,IIP3 is -4.5dBm,NF is 17dB,the maximum transient power dissipation is 9.3mW,and DC power dissipation is 9.2mW.The mixer’s noise and linearity analyses are also presented.展开更多
Radiation-induced 1/f noise degradation in the LM117 bipolar linear voltage regulator is studied. Based on the radiation-induced degradation mechanism of the output voltage, it is suggested that the band-gap reference...Radiation-induced 1/f noise degradation in the LM117 bipolar linear voltage regulator is studied. Based on the radiation-induced degradation mechanism of the output voltage, it is suggested that the band-gap reference subcircuit is the critical component which leads to the 1/f noise degradation of the LM117. The radiation makes the base surface current of the bipolar junction transistors of the band-gap reference subcircuit increase, which leads to an increase in the output 1/f noise of the LM117. Compared to the output voltage, the 1/f noise parameter is more sensitive, it may be used to evaluate the radiation resistance capability of LM117.展开更多
In this paper, we reviewed our common phase error (CPE) and intercarrier interference (ICI) compensation methods for coherent optical orthogonal frequency division multiplexing (CO-OFDM) system. We first present...In this paper, we reviewed our common phase error (CPE) and intercarrier interference (ICI) compensation methods for coherent optical orthogonal frequency division multiplexing (CO-OFDM) system. We first presented a unified CPE estimation framework combining decision-aided (DA), pilot-aided (PA) and decision feed- back (DF) algorithms. The DA method is used to estimate the CPE of the current OFDM symbol based on the decision statistics of the previous symbol. DA + PA helps increase the phase noise tolerance of DA and reduce the overhead of PA, while DA + DF reduces the overhead to zero, achieving best performance with one more step of estimation, compensation and demodulation. We also described a modified time-domain blind intercarrier interference (BL-ICI) mitigation algorithm over non- constant amplitude formats. The new algorithm is derived from the BL-ICI algorithm over constant amplitude format for wireless networks. A new power estimation scheme was proposed for the BL-ICI algorithm to adapt to non- constant amplitude format. It has the same order of complexity with frequency domain decision-aided ICI (DA-ICI) compensation method and does not suffer from symbol decision errors. The effectiveness of both CPE and ICI compensation algorithms were demonstrated in a simulated 56-Gbit/s CO-OFDM system with various modulation formats.展开更多
A voltage-controlled oscillator(VCO) with dual stages of accumulation mode varactors for a multimode global navigation satellite system(GNSS) application,which adopts sigma-delta fractional-N technology in the syn...A voltage-controlled oscillator(VCO) with dual stages of accumulation mode varactors for a multimode global navigation satellite system(GNSS) application,which adopts sigma-delta fractional-N technology in the synthesizer,is presented.The structure is selected to optimize the frequency coverage and tuning linearity, based on a general analysis of the parasitic capacitance in the coarse tuning switch bank cells,which cover the global positioning system(GPS) and Beidou(BD) bands.The VCO implemented in the 0.18μm CMOS process can cover the GPS L1,BD B1,B2 and B3 bands with sufficient margin,and exhibits low phase noise by using this tuning curve linearization technique.The equalized K_(vco),characteristic behavior further offers a wide voltage tuning range and improves the stability of the closed loop.展开更多
文摘A 1.34 GHz-1=60 MHz low noise amplifier (LNA) designed in a 0.35 pm SiGe process is presented. The designed LNA exhibits a power gain of 21.46 dB and a noise figure (NF) of 1.27 dB at 1.34 GHz. The linearity is improved with an active biasing technique. The post-layout simulation shows an input referred 1-dB compression point (IPldn) of-11.52 dBm. Compared with the recent reported high gain LNAs, the proposed LNA has a much better linearity without degrading other performance. The LNA draws 10 mA current from a 3.3 V power supply.
基金Project supported by the National Natural Science Foundation of China (Grant No. 10721403)the National Basic Research Program of China (Grant No. 2009CB918500)
文摘A typical biological cell lives in a small volmne at room temperature; the noise effect on the cell signal transduction pathway may play an important role in its dynamics. Here, using the transforming growth factor-β signal transduction pathway as an example, we report our stochastic simulations of the dynamics of the pathway and introduce a linear noise approximation method to calculate the transient intrinsic noise of pathway components. We compare the numerical solutions of the linear noise approximation with the statistic results of chemical Langevin equations, and find that they are quantitatively in agreement with the other. When transforming growth factor-β dose decreases to a low level, the time evolution of noise fluctuation of nuclear Smad2-Smad4 complex indicates the abnormal enhancement in the transient signal activation process.
基金Project supported by the Fundamental Research Funds for the Central Universities,China(Grant Nos.2662015QC041 and 2662014BQ069)the Huazhong Agricultural University Scientific&Technological Self-innovation Foundation,China(Grant No.2015RC021)the National Natural Science Foundation of China(Grant Nos.11675060,91730301,11547244,and 11474117)
文摘Feed-forward gene transcriptional regulatory networks, as a set of common signal motifs, are widely distributed in the biological systems. In this paper, the noise characteristics and propagation mechanism of various feed-forward gene transcriptional regulatory loops are investigated, including (i) coherent feed-forward loops with AND-gate, (ii) coherent feed-forward loops with OR-gate logic, and (iii) incoherent feed-forward loops with AND-gate logic. By introducing logarithmic gain coefficient and using linear noise approximation, the theoretical formulas of noise decomposition are derived and the theoretical results are verified by Gillespie simulation. From the theoretical and numerical results of noise decomposition algorithm, three general characteristics about noise transmission in these different kinds of feed-forward loops are observed, i) The two-step noise propagation of upstream factor is negative in the incoherent feed-forward loops with AND-gate logic, that is, upstream factor can indirectly suppress the noise of downstream factors, ii) The one-step propagation noise of upstream factor is non-monotonic in the coherent feed-forward loops with OR-gate logic, iii) When the branch of the feed-forward loop is negatively controlled, the total noise of the downstream factor monotonically increases for each of all feed-forward loops. These findings are robust to variations of model parameters. These observations reveal the universal rules of noise propagation in the feed-forward loops, and may contribute to our understanding of design principle of gene circuits.
文摘A new architecture of CMOS low voltage downconve rsion mixer is presented.With 1.452GHz LO input and 1.45GHz RF input,simulation results show that the conversion gain is 15dB,IIP3 is -4.5dBm,NF is 17dB,the maximum transient power dissipation is 9.3mW,and DC power dissipation is 9.2mW.The mixer’s noise and linearity analyses are also presented.
基金Project supported by the National Natural Science Foundation of China(Nos.61076101,61204092)
文摘Radiation-induced 1/f noise degradation in the LM117 bipolar linear voltage regulator is studied. Based on the radiation-induced degradation mechanism of the output voltage, it is suggested that the band-gap reference subcircuit is the critical component which leads to the 1/f noise degradation of the LM117. The radiation makes the base surface current of the bipolar junction transistors of the band-gap reference subcircuit increase, which leads to an increase in the output 1/f noise of the LM117. Compared to the output voltage, the 1/f noise parameter is more sensitive, it may be used to evaluate the radiation resistance capability of LM117.
文摘In this paper, we reviewed our common phase error (CPE) and intercarrier interference (ICI) compensation methods for coherent optical orthogonal frequency division multiplexing (CO-OFDM) system. We first presented a unified CPE estimation framework combining decision-aided (DA), pilot-aided (PA) and decision feed- back (DF) algorithms. The DA method is used to estimate the CPE of the current OFDM symbol based on the decision statistics of the previous symbol. DA + PA helps increase the phase noise tolerance of DA and reduce the overhead of PA, while DA + DF reduces the overhead to zero, achieving best performance with one more step of estimation, compensation and demodulation. We also described a modified time-domain blind intercarrier interference (BL-ICI) mitigation algorithm over non- constant amplitude formats. The new algorithm is derived from the BL-ICI algorithm over constant amplitude format for wireless networks. A new power estimation scheme was proposed for the BL-ICI algorithm to adapt to non- constant amplitude format. It has the same order of complexity with frequency domain decision-aided ICI (DA-ICI) compensation method and does not suffer from symbol decision errors. The effectiveness of both CPE and ICI compensation algorithms were demonstrated in a simulated 56-Gbit/s CO-OFDM system with various modulation formats.
文摘A voltage-controlled oscillator(VCO) with dual stages of accumulation mode varactors for a multimode global navigation satellite system(GNSS) application,which adopts sigma-delta fractional-N technology in the synthesizer,is presented.The structure is selected to optimize the frequency coverage and tuning linearity, based on a general analysis of the parasitic capacitance in the coarse tuning switch bank cells,which cover the global positioning system(GPS) and Beidou(BD) bands.The VCO implemented in the 0.18μm CMOS process can cover the GPS L1,BD B1,B2 and B3 bands with sufficient margin,and exhibits low phase noise by using this tuning curve linearization technique.The equalized K_(vco),characteristic behavior further offers a wide voltage tuning range and improves the stability of the closed loop.