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Enhanced structural damage behavior of liquid-filled tank by reactive material projectile impact 被引量:1
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作者 Jianwen Xie Yuanfeng Zheng +4 位作者 Zhenyang Liu Chengzhe Liu Aoxin Liu Pengwan Chen Haifu Wang 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第1期211-229,共19页
A series of ballistic experiments were performed to investigate the damage behavior of high velocity reactive material projectiles(RMPs) impacting liquid-filled tanks,and the corresponding hydrodynamic ram(HRAM) was s... A series of ballistic experiments were performed to investigate the damage behavior of high velocity reactive material projectiles(RMPs) impacting liquid-filled tanks,and the corresponding hydrodynamic ram(HRAM) was studied in detail.PTFE/Al/W RMPs with steel-like and aluminum-like densities were prepared by a pressing/sintering process.The projectiles impacted a liquid-filled steel tank with front aluminum panel at approximately 1250 m/s.The corresponding cavity evolution characteristics and HRAM pressure were recorded by high-speed camera and pressure acquisition system,and further compared to those of steel and aluminum projectiles.Significantly different from the conical cavity formed by the inert metal projectile,the cavity formed by the RMP appeared as an ellipsoid with a conical front.The RMPs were demonstrated to enhance the radial growth velocity of cavity,the global HRAM pressure amplitude and the front panel damage,indicating the enhanced HRAM and structural damage behavior.Furthermore,combining the impact-induced fragmentation and deflagration characteristics,the cavity evolution of RMPs under the combined effect of kinetic energy impact and chemical energy release was analyzed.The mechanism of enhanced HRAM pressure induced by the RMPs was further revealed based on the theoretical model of the initial impact wave and the impulse analysis.Finally,the linear correlation between the deformation-thickness ratio and the non-dimensional impulse for the front panel was obtained and analyzed.It was determined that the enhanced near-field impulse induced by the RMPs was the dominant reason for the enhanced structural damage behavior. 展开更多
关键词 Reactive material projectile Hydrodynamic ram Enhanced structural damage liquid-filled tank Impact
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Meningeal lymphatic vessel crosstalk with central nervous system immune cells in aging and neurodegenerative diseases
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作者 Minghuang Gao Xinyue Wang +5 位作者 Shijie Su Weicheng Feng Yaona Lai Kongli Huang Dandan Cao Qi Wang 《Neural Regeneration Research》 SCIE CAS 2025年第3期763-778,共16页
Meningeal lymphatic vessels form a relationship between the nervous system and periphery, which is relevant in both health and disease. Meningeal lymphatic vessels not only play a key role in the drainage of brain met... Meningeal lymphatic vessels form a relationship between the nervous system and periphery, which is relevant in both health and disease. Meningeal lymphatic vessels not only play a key role in the drainage of brain metabolites but also contribute to antigen delivery and immune cell activation. The advent of novel genomic technologies has enabled rapid progress in the characterization of myeloid and lymphoid cells and their interactions with meningeal lymphatic vessels within the central nervous system. In this review, we provide an overview of the multifaceted roles of meningeal lymphatic vessels within the context of the central nervous system immune network, highlighting recent discoveries on the immunological niche provided by meningeal lymphatic vessels. Furthermore, we delve into the mechanisms of crosstalk between meningeal lymphatic vessels and immune cells in the central nervous system under both homeostatic conditions and neurodegenerative diseases, discussing how these interactions shape the pathological outcomes. Regulation of meningeal lymphatic vessel function and structure can influence lymphatic drainage, cerebrospinal fluid-borne immune modulators, and immune cell populations in aging and neurodegenerative disorders, thereby playing a key role in shaping meningeal and brain parenchyma immunity. 展开更多
关键词 central nervous system meningeal lymphatic vessels IMMUNITY myeloid cells lymphatic cells neurodegenerative disease
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Attitude maneuver of liquid-filled spacecraft with a flexible appendage by momentum wheel 被引量:6
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作者 Dan-Dan Yang Bao-Zeng Yue +2 位作者 Wen-Jun Wu Xiao-Juan Song Le-Mei Zhu 《Acta Mechanica Sinica》 SCIE EI CAS CSCD 2012年第2期543-550,共8页
Attitude maneuver of liquid-filled spacecraft with an appendage as a cantilever beam by momentum wheel is studied. The dynamic equations are derived by conserva- tion of angular momentum and force equilibrium principl... Attitude maneuver of liquid-filled spacecraft with an appendage as a cantilever beam by momentum wheel is studied. The dynamic equations are derived by conserva- tion of angular momentum and force equilibrium principle. A feedback control strategy of the momentum wheel is ap- plied for the attitude maneuver. The residual nutation of the spacecraft in maneuver process changes with some chosen parameters, such as steady state time, locations of the liq- uid container and the appendage, and appendage parame- ters. The results indicate that locations in the second and fourth quadrants of the body-fixed coordinate system and the second quadrant of the wall of the main body are better choices for.placing the liquid containers and the appendage than other locations if they can be placed randomly. Higher density and thicker cross section are better for lowering the residual nutation if they can be changed. Light appendage can be modeled as a rigid body, which results in a larger residual nutation than a flexible model though. The resid- ual nutation decreases with increasing absolute value of the initial sloshing angular height. 展开更多
关键词 liquid-filled spacecraft Appendage Attitude maneuver Momentum wheel Steady state time Residual nutation
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Laboratory-scale investigation of response characteristics of liquid-filled rock joints with different joint inclinations under dynamic loading 被引量:5
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作者 Jin Huang Xiaoli Liu +3 位作者 Danqing Song Jian Zhao Enzhi Wang Jianmin Zhang 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2022年第2期396-406,共11页
In underground rock engineering,water-bearing faults may be subjected to dynamic loading,resulting in the coupling of hydraulic and dynamic hazards.Understanding the interaction mechanism between the stress waves indu... In underground rock engineering,water-bearing faults may be subjected to dynamic loading,resulting in the coupling of hydraulic and dynamic hazards.Understanding the interaction mechanism between the stress waves induced by dynamic loadings and liquid-filled rock joints is therefore crucial.In this study,an auxiliary device for simulating the liquid-filled layer was developed to analyze the dynamic response characteristics of liquid-filled rock joints in laboratory.Granite and polymethyl methacrylate(PMMA)specimens were chosen for testing,and high-amplitude shock waves induced by a split Hopkinson pressure bar(SHPB)were used to produce dynamic loadings.Impact loading tests were conducted on liquid-filled rock joints with different joint inclinations.The energy propagation coefficient and peak liquid pressure were proposed to investigate the energy propagation and attenuation of waves propagating across the joints,as well as the dynamic response characteristics of the liquid in the liquid-filled rock joints.For the inclination angle range considered herein,the experimental results showed that the energy propagation coefficient gently diminished with increasing joint inclination,and smaller coefficient values were obtained for granite specimens compared with PMMA specimens.The peak liquid pressure exhibited a gradually decreasing trend with increasing joint inclination,and the peak pressure for granite specimens was slightly higher than that for PMMA specimens.Overall,this paper may provide a considerably better method for studying liquid-filled rock joints at the laboratory scale,and serves as a guide for interpreting the underlying mechanisms for interactions between stress waves and liquid-filled rock joints. 展开更多
关键词 liquid-filled rock joint Stress wave Laboratory investigation Wave propagation characteristics Liquid dynamic response
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Growth model of cavity generated by the projectile impacting liquid-filled tank 被引量:3
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作者 Bei-lei Zhao Ji-guang Zhao +2 位作者 Cun-yan Cui Yong-sheng Duan Yan Wang 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2020年第3期609-616,共8页
The high-speed impact of a projectile on a liquid-filled tank causes the hydraulic ram,in which a cavity is formed.To study the growth characteristics of the cavity,the formation mechanism of the cavity is analyzed.Th... The high-speed impact of a projectile on a liquid-filled tank causes the hydraulic ram,in which a cavity is formed.To study the growth characteristics of the cavity,the formation mechanism of the cavity is analyzed.The effect of Reynolds number and Mach number on drag coefficient is considered,the axial and radial growth models of the cavity are established respectively.The relative errors between the cavity length calculated by the axial growth model,the cavity diameter calculated by the radial growth model and Ma L.Y.test results are less than 20%,which verifies the effectiveness of the axial and radial growth models.Finally,numerical simulation is carried out to study the growth characteristics of the cavity caused by the projectile impacting the satellite tank at the velocity of 4000 m/s.The cavity length and diameter calculated by the axial and radial growth models agree well with those obtained by simulation results,indicating that the cavity length and diameter in satellite tank can be accurately calculated by the axial and radial growth models. 展开更多
关键词 PROJECTILE Impact liquid-filled tank CAVITY Axial growth model Radial growth model
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Coupling dynamic analysis of a liquid-filled spherical container subject to arbitrary excitation 被引量:4
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作者 Jing Lü Shimin Wang Tianshu Wang 《Acta Mechanica Sinica》 SCIE EI CAS CSCD 2012年第4期1154-1162,共9页
Using spherical coordinates, the coupling nonlinear dynamic system of a liquid-filled spherical tank, which can be excited discretionarily, is deduced by the H-O varia- tional principle, and the viscous damping is int... Using spherical coordinates, the coupling nonlinear dynamic system of a liquid-filled spherical tank, which can be excited discretionarily, is deduced by the H-O varia- tional principle, and the viscous damping is introduced via the liquid dissipation function. The kinetic equations of the coupling system are deduced by the relationship between the velocity of liquid particles and the disturbed liquid surface equation. Normal differential equations are obtained through the Galerkin method. An equivalent mechanical model is developed for liquid sloshing in a spherical tank subject to arbitrary excitation. The fixed and slosh masses, as well as the spring and damping constants, are determined in such a way as to satisfy the principle of equivalence. Numerical simulations illustrate the theoretical results in this paper as well. 展开更多
关键词 liquid-filled spherical tank. Coupling nonlinear system Arbitrary excitation Equivalent mechanical model Spherical coordinates
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Dynamic response of liquid-filled rectangular tank with elastic appendages under pitching excitation 被引量:2
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作者 吕敬 李俊峰 王天舒 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI 2007年第3期351-359,共9页
Nonlinear dynamics of liquid-filled rectangular tank with elastic appendages are studied. Based on the assumption of ideal fluid, the coupling dynamic equations of rigid tank, elastic appendages and liquid fuel are de... Nonlinear dynamics of liquid-filled rectangular tank with elastic appendages are studied. Based on the assumption of ideal fluid, the coupling dynamic equations of rigid tank, elastic appendages and liquid fuel are derived using H-O principle. In the case of pitch excitation, the modified potential function and wave height function are introduced to describe the moving boundary of fluid, then Galerkin's method is used to discretize the dynamic equations into ordinary differential equations. The natural frequencics of the coupling system are formulated in liquid depth, the length of the tank, etc. The formulae are confirmed by numerical simulations, which also show that the effects of liquid and elastic appendages on the attitude angular of rigid. 展开更多
关键词 liquid-filled rectangular tank elastic appendage nonlinear dynamics natural frequency PITCH
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EXPERIMENTAL INVESTIGATION AND COMPUTER SIMULATION ON DYNAMIC BUCKLING BEHAVIOR OF LIQUID-FILLED CYLINDRICAL SHELLS UNDER AXIAL IMPACT 被引量:2
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作者 Zhang, SY Lei, JP +2 位作者 Zhao, LM Cheng, GQ Lu, GY 《Acta Mechanica Solida Sinica》 SCIE EI 2000年第2期166-172,共7页
This article reports an experimental investigation on the axial impact buckling of thin metallic cylindrical shells fully filled with water. Low velocity impact tests are carried out by DHR-9401 drop hammer rig. The w... This article reports an experimental investigation on the axial impact buckling of thin metallic cylindrical shells fully filled with water. Low velocity impact tests are carried out by DHR-9401 drop hammer rig. The whole process of dynamic buckling is simulated using LS-DYNA computer code. The consistency between experimental observation and numerical simulation is quite satisfactory. The investigation indicates that quite high internal hydrodynamic pressure occurs inside the shell during the impact process. Under the combined action of the high internal pressure and axial compression plastic buckling occurs easily in the thin-walled shells and buckling modes take on regular and axisymmetric wrinkles. 展开更多
关键词 liquid-filled cylindrical shell impact buckling experimental investigation computer simulation
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Improved frequency modeling and solution for parallel liquid-filled pipes considering both fluid-structure interaction and structural coupling 被引量:3
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作者 Xumin GUO Chunliang XIAO +3 位作者 Hui MA Hui LI Xufang ZHANG Bangchun WEN 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI CSCD 2022年第8期1269-1288,共20页
The dynamic characteristics of a single liquid-filled pipe have been broadly studied in the previous literature.The parallel liquid-filled pipe(PLFP)system is also widely used in engineering,and its structure is more ... The dynamic characteristics of a single liquid-filled pipe have been broadly studied in the previous literature.The parallel liquid-filled pipe(PLFP)system is also widely used in engineering,and its structure is more complex than that of a single pipe.However,there are few reports about the dynamic characteristics of the PLFPs.Therefore,this paper proposes improved frequency modeling and solution for the PLFPs,involving the logical alignment principle and coupled matrix processing.The established model incorporates both the fluid-structure interaction(FSI)and the structural coupling of the PLFPs.The validity of the established model is verified by modal experiments.The effects of some unique parameters on the dynamic characteristics of the PLFPs are discussed.This work provides a feasible method for solving the FSI of multiple pipes in parallel and potential theoretical guidance for the dynamic analysis of the PLFPs in engineering. 展开更多
关键词 parallel liquid-filled pipe(PLFP) dynamic analysis improved frequency modeling and solution fluid-structure interaction(FSI) structure coupling
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Study on liquid-filled structure target with shaped charge vertical penetration 被引量:1
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作者 Min Guo Xu-dong Zu +1 位作者 Xiao-jun Shen Zheng-xiang Huang 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2019年第6期861-867,共7页
Based on the characteristic expanded hole of a shaped charge jet(SCJ) for target penetration and the reflow characteristics of liquids,the liquid-filled structure of a target disturbs the stability of the SCJ acquired... Based on the characteristic expanded hole of a shaped charge jet(SCJ) for target penetration and the reflow characteristics of liquids,the liquid-filled structure of a target disturbs the stability of the SCJ acquired in two independent parts.The interference jet speed interval,the escape jet speed interval,and the surplus depth are calculated on the basis of the virtual origin theory.The experimental results,including the velocity of the escaped jet tip and the surplus depth of penetration,are consistent with the theoretical results.Experiments show that the theory can describe the interaction process of the target with a shaped charge jet. 展开更多
关键词 Shaped charge liquid-filled structure target Disturbed jet Escape jet
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Parameter design of a liquid-filled sloshing system
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作者 钟顺 陈予恕 《Chinese Physics B》 SCIE EI CAS CSCD 2012年第12期298-304,共7页
The nonlinear governing equations of the liquid sloshing modals in a cylindrical storage tank are established. Through analytical analysis, the analytical expressions of the solutions of this kind of system are obtain... The nonlinear governing equations of the liquid sloshing modals in a cylindrical storage tank are established. Through analytical analysis, the analytical expressions of the solutions of this kind of system are obtained. With different parameters, the dynamical behaviors of the solutions are different from the trivial ones. To prevent system instability, two selection principles that the stiffness equations are positive-definite and the nonlinear terms of the system are not regenerative elements are given. Meanwhile, numerical simulations are also given, which confirm the analytical results. 展开更多
关键词 liquid-filled system analytical analysis selection principle INSTABILITY
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Axial power flow distributions of ultrasonic guided waves in viscous liquid-filled pipes
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作者 TA Dean (Department of Electronic Engineering, Fudan University, Shanghai 200433, China) 《声学技术》 CSCD 2004年第S1期18-22,共5页
The axial power flow (APF) magnitude and attenuation distributions of ultrasonic longitudinal guided waves in viscous liquid-filled elastic pipes are investigated. The optimal location, optimal mode and its frequency-... The axial power flow (APF) magnitude and attenuation distributions of ultrasonic longitudinal guided waves in viscous liquid-filled elastic pipes are investigated. The optimal location, optimal mode and its frequency-thickness product (fd) for the test of pipes filled with viscous liquid are chosen according to APF and attenuation distributions. The results show that the APF magnitude distribution is an important parameter in choosing the modes and parameters. A particular mode has weak dispersion in ranges of fd values with large group velocity, while other modes with smaller group velocity in the same fd ranges have stronger dispersion. It has been observed that, within these ranges, the chosen mode has a larger APF on the (pipe’s) wall. Therefore, in the region of fd values where a particular mode has a large group velocity, this mode will be effective to be used in testing elastic pipes filled with viscous liquid. The results obtained from both the APF analysis and attenuation distribution are consistent. 展开更多
关键词 guided waves VISCOUS liquid-filled elastic PIPES AXIAL power flow (APF) ATTENUATION
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A dark hollow beam from a selectively liquid-filled photonic crystal fibre
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作者 张美艳 李曙光 +2 位作者 姚艳艳 付博 张磊 《Chinese Physics B》 SCIE EI CAS CSCD 2010年第4期339-344,共6页
This paper reports that, based on the electromagnetic scattering theory of the multipole method, a high-quality hollow beam is produced through a selectively liquid-filled photonic crystal fibre. Instead of a doughnut... This paper reports that, based on the electromagnetic scattering theory of the multipole method, a high-quality hollow beam is produced through a selectively liquid-filled photonic crystal fibre. Instead of a doughnut shape, a typical hollow beam is produced by other methods; the mode-field images of the hollow-beam photonic crystal fibre satisfy sixth-order rotation symmetry, according to the symmetry of the photonic crystal fibre (PCF) structure. A dark spot size of the liquid-filled photonic crystal fibre-generated hollow beam can be tuned by inserting liquid into the cladding region and varying the photonic crystal fibre structure parameters. The liquid-filled PCF makes a convenient and flexible tool for the guiding and trapping of atoms and the creation of all-fibre optical tweezers. 展开更多
关键词 liquid-filled photonic crystal fibre fundamental mode dark hollow beam
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Nonlinear dynamic model and control of three-axis stabilized liquid-filled spacecraft attitude system
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作者 张龙 段广仁 张永安 《Journal of Harbin Institute of Technology(New Series)》 EI CAS 2012年第5期107-112,共6页
The fuel slosh in the storage tanks affects the attitude dynamics of the liquid-filled spacecraft during orbit transferring. To describe the interactions between the fuel slosh dynamics and the spacecraft attitude dyn... The fuel slosh in the storage tanks affects the attitude dynamics of the liquid-filled spacecraft during orbit transferring. To describe the interactions between the fuel slosh dynamics and the spacecraft attitude dynamics, a novel nonlinear dynamic model for three-axis liquid-filled spacecraft is presented, and in this paper, the multi-body dynamics method is utilized. In this model, the fuel slosh is represented by the motions of an equivalent sphere pendulum, and the fuel slosh is underactuated. The proposed dynamics model meets the demand of attitude controller design of liquid-filled spacecraft. Then, a nonlinear proportional-plus-derivative (PD) type controller is designed for the proposed model based on the Lyapunov direct approach. This controller can suppress the fuel slosh and stabilize the attitude of the liquid-filled spacecraft. Numerical simulations are presented to verify the effectiveness of the proposed nonlinear dynamic model and the designed underactuated controller when compared with the conventional control scheme. 展开更多
关键词 liquid-filled spacecraft nonlinear dynamics fuel slosh underactuated control attitude control
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Blood-brain barrier pathology in cerebral small vessel disease 被引量:5
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作者 Ruxue Jia Gemma Solé-Guardia Amanda J.Kiliaan 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第6期1233-1240,共8页
Cerebral small vessel disease is a neurological disease that affects the brain microvasculature and which is commonly observed among the elderly.Although at first it was considered innocuous,small vessel disease is no... Cerebral small vessel disease is a neurological disease that affects the brain microvasculature and which is commonly observed among the elderly.Although at first it was considered innocuous,small vessel disease is nowadays regarded as one of the major vascular causes of dementia.Radiological signs of small vessel disease include small subcortical infarcts,white matter magnetic resonance imaging hyperintensities,lacunes,enlarged perivascular spaces,cerebral microbleeds,and brain atrophy;however,great heterogeneity in clinical symptoms is observed in small vessel disease patients.The pathophysiology of these lesions has been linked to multiple processes,such as hypoperfusion,defective cerebrovascular reactivity,and blood-brain barrier dysfunction.Notably,studies on small vessel disease suggest that blood-brain barrier dysfunction is among the earliest mechanisms in small vessel disease and might contribute to the development of the hallmarks of small vessel disease.Therefore,the purpose of this review is to provide a new foundation in the study of small vessel disease pathology.First,we discuss the main structural domains and functions of the blood-brain barrier.Secondly,we review the most recent evidence on blood-brain barrier dysfunction linked to small vessel disease.Finally,we conclude with a discussion on future perspectives and propose potential treatment targets and interventions. 展开更多
关键词 blood-brain barrier dysfunction cerebral blood flow cerebral hypoperfusion endothelial dysfunction HYPERTENSION inflammation magnetic resonance imaging neurovascular unit oxidative stress small vessel disease tight junctions TRANSCYTOSIS
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Repeatability,interocular correlation and agreement of optic nerve head vessel density in healthy eyes:a sweptsource optical coherence tomographic angiography study 被引量:1
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作者 Dan-Qi Fang Da-Wei Yang +2 位作者 Xiao-Ting Mai Carol Y Cheung Hao-Yu Chen 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2024年第5期896-903,共8页
AIM:To assess the repeatability,interocular correlation,and agreement of quantitative swept-source optical coherence tomography angiography(OCTA)optic nerve head(ONH)parameters in healthy subjects.METHODS:Thir ty-thre... AIM:To assess the repeatability,interocular correlation,and agreement of quantitative swept-source optical coherence tomography angiography(OCTA)optic nerve head(ONH)parameters in healthy subjects.METHODS:Thir ty-three healthy subjects were enrolled.The ONH of both eyes were imaged four times by a swept-source-OCTA using a 3 mm×3 mm scanning protocol.Images of the radial peripapillary capillary were analyzed by a customized Matlab program,and the vessel density,fractal dimension,and vessel diameter index were measured.The repeatability of the four scans was determined by the intraclass correlation coefficient(ICC).The most well-centered optic disc from the four repeated scans was then selected for the interocular correlation and agreement analysis using the Pearson correlation coefficient,ICC and Bland-Altman plots.RESULTS:All swept-source-OCTA ONH parameters exhibited certain repeatability,with ICC>0.760 and coefficient of variation(CoV)≤7.301%.The obvious interocular correlation was observed for papillary vessel density(ICC=0.857),vessel diameter index(ICC=0.857)and fractal dimension(ICC=0.906),while circumpapillary vessel density exhibited moderate interocular correlation(ICC=0.687).Bland-Altman plots revealed an agreement range of-5.26%to 6.21%for circumpapillary vessel density.CONCLUSION:OCTA ONH parameters demonstrate good repeatability in healthy subjects.The interocular correlations of papillary vessel density,fractal dimension and vessel diameter index are high,but the correlation for circumpapillary vessel density is moderate. 展开更多
关键词 interocular correlation REPEATABILITY optic nerve head optical coherence tomography angiography vessel density
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Cognitive impairment in cerebral small vessel disease induced by hypertension 被引量:2
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作者 Weipeng Wei Denglei Ma +1 位作者 Lin Li Lan Zhang 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第7期1454-1462,共9页
Hypertension is a primary risk factor for the progression of cognitive impairment caused by cerebral small vessel disease,the most common cerebrovascular disease.Howeve r,the causal relationship between hypertension a... Hypertension is a primary risk factor for the progression of cognitive impairment caused by cerebral small vessel disease,the most common cerebrovascular disease.Howeve r,the causal relationship between hypertension and cerebral small vessel disease remains unclear.Hypertension has substantial negative impacts on brain health and is recognized as a risk factor for cerebrovascular disease.Chronic hypertension and lifestyle factors are associated with risks for stro ke and dementia,and cerebral small vessel disease can cause dementia and stroke.Hypertension is the main driver of cerebral small vessel disease,which changes the structure and function of cerebral vessels via various mechanisms and leads to lacunar infarction,leukoaraiosis,white matter lesions,and intracerebral hemorrhage,ultimately res ulting in cognitive decline and demonstrating that the brain is the to rget organ of hypertension.This review updates our understanding of the pathogenesis of hypertensioninduced cerebral small vessel disease and the res ulting changes in brain structure and function and declines in cognitive ability.We also discuss drugs to treat cerebral small vessel disease and cognitive impairment. 展开更多
关键词 blood-brain barrier cerebral small vessel disease cognitive impairment DEMENTIA endothelial dysfunction enlarged perivascular space HYPERTENSION lacunar infarction NEUROINFLAMMATION TREATMENT white matter high signal intensity
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Bio-Inspired Screwed Conduits from the Microfluidic Rope-Coiling Effect for Microvessels and Bronchioles
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作者 Rui Liu Jiahui Guo +3 位作者 Bin Kong Yunru Yu Yuanjin Zhao Lingyun Sun 《Engineering》 SCIE EI CAS CSCD 2024年第10期172-178,共7页
Tubular microfibers have recently attracted extensive interest for applications in tissue engineering.However,the fabrication of tubular fibers with intricate hierarchical structures remains a major challenge.Here,we ... Tubular microfibers have recently attracted extensive interest for applications in tissue engineering.However,the fabrication of tubular fibers with intricate hierarchical structures remains a major challenge.Here,we present a novel one-step microfluidic spinning method to generate bio-inspired screwed conduits(BSCs).Based on the microfluidic rope-coiling effect,a viscous hydrogel precursor is first curved into a helix stream in the channel,and then consecutively packed as a hollow structured stream and gelated into a screwed conduit(SC)via ionic and covalent crosslinking.By taking advantage of the excellent fluid-controlling ability of microfluidics,various tubes with diverse structures are fabricated via simple control over fluid velocities and multiple microfluidic device designs.The perfusability and permeability results,as well as the encapsulation and culture of human umbilical vein endothelial cells(HUVECs),human pulmonary alveolar epithelial cells(HPAs),and myogenic cells(C2C12),demonstrate that these SCs have good perfusability and permeability and the ability to induce the formation of functional biostructures.These features support the uniqueness and potential applications of these BSCs as biomimetic blood vessels and bronchiole tissues in combination with tissue microstructures,with likely application possibilities in biomedical engineering. 展开更多
关键词 BIO-INSPIRED Microfluidics MICROFIBER Tissue engineering Bronchiole vessel
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An Efficient Long Short-Term Memory and Gated Recurrent Unit Based Smart Vessel Trajectory Prediction Using Automatic Identification System Data
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作者 Umar Zaman Junaid Khan +4 位作者 Eunkyu Lee Sajjad Hussain Awatef Salim Balobaid Rua Yahya Aburasain Kyungsup Kim 《Computers, Materials & Continua》 SCIE EI 2024年第10期1789-1808,共20页
Maritime transportation,a cornerstone of global trade,faces increasing safety challenges due to growing sea traffic volumes.This study proposes a novel approach to vessel trajectory prediction utilizing Automatic Iden... Maritime transportation,a cornerstone of global trade,faces increasing safety challenges due to growing sea traffic volumes.This study proposes a novel approach to vessel trajectory prediction utilizing Automatic Identification System(AIS)data and advanced deep learning models,including Long Short-Term Memory(LSTM),Gated Recurrent Unit(GRU),Bidirectional LSTM(DBLSTM),Simple Recurrent Neural Network(SimpleRNN),and Kalman Filtering.The research implemented rigorous AIS data preprocessing,encompassing record deduplication,noise elimination,stationary simplification,and removal of insignificant trajectories.Models were trained using key navigational parameters:latitude,longitude,speed,and heading.Spatiotemporal aware processing through trajectory segmentation and topological data analysis(TDA)was employed to capture dynamic patterns.Validation using a three-month AIS dataset demonstrated significant improvements in prediction accuracy.The GRU model exhibited superior performance,achieving training losses of 0.0020(Mean Squared Error,MSE)and 0.0334(Mean Absolute Error,MAE),with validation losses of 0.0708(MSE)and 0.1720(MAE).The LSTM model showed comparable efficacy,with training losses of 0.0011(MSE)and 0.0258(MAE),and validation losses of 0.2290(MSE)and 0.2652(MAE).Both models demonstrated reductions in training and validation losses,measured by MAE,MSE,Average Displacement Error(ADE),and Final Displacement Error(FDE).This research underscores the potential of advanced deep learning models in enhancing maritime safety through more accurate trajectory predictions,contributing significantly to the development of robust,intelligent navigation systems for the maritime industry. 展开更多
关键词 Trajectory prediction AIS data smart vessel deep learning LSTM GRU
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Research on Leak Location of Liquid-filled Pipe Based on Frequency Dispersion Characteristics
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作者 Lijun XIONG Ping LU +1 位作者 Yun YANG Li LI 《Mechanical Engineering Science》 2021年第1期19-27,共9页
Due to the material problems and force majeure factors,the leakage will be occurred on the liquid-filled pipe resulting in waste of resources,environmental pollution and even endangering safety.Acoustic wave detection... Due to the material problems and force majeure factors,the leakage will be occurred on the liquid-filled pipe resulting in waste of resources,environmental pollution and even endangering safety.Acoustic wave detection technology is widely used in buried pipeline leak detection,this technology mainly uses the wave(n=0,s=1)in the pipeline acoustic wave to locate the leak.When the leakage acoustic signal propagates along the liquid-filled pipe,the frequency dispersion characteristics can be obtained by wavelet decomposition.And there is a time delay(time difference)value between the leaky acoustic signals collected by the sensors at both ends of the leak.The outputs show that the results obtained by wavelet decomposition are in good agreement with the theoretical calculation results.Based on the obtained dispersion relation,the time delay values at different characteristic frequencies are analyzed by the cross-correlation method,and the leak location accuracy is discussed.This research content provides theoretical support and engineering application guidance for pipe leakage location technology. 展开更多
关键词 liquid-filled pipe Frequency dispersion characteristics Leak location Time delay estimation value
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