Severe lithium intoxication requires intensive and prolonged hemodialysis as a definitive therapeutic measure. Such an aggressive stand is often needed to prevent the post-dialytic rebound in plasma lithium levels as ...Severe lithium intoxication requires intensive and prolonged hemodialysis as a definitive therapeutic measure. Such an aggressive stand is often needed to prevent the post-dialytic rebound in plasma lithium levels as a result of the drug＇s relatively slow equilibration across cellular membranes. Use of a conventional, phosphorus-free, bicarbonate-based dialysis solution in the course of a dialytic treatment may engender hypophosphatemia in these individuals.展开更多
文摘Severe lithium intoxication requires intensive and prolonged hemodialysis as a definitive therapeutic measure. Such an aggressive stand is often needed to prevent the post-dialytic rebound in plasma lithium levels as a result of the drug＇s relatively slow equilibration across cellular membranes. Use of a conventional, phosphorus-free, bicarbonate-based dialysis solution in the course of a dialytic treatment may engender hypophosphatemia in these individuals.
