Objective:To study the antimicrobial activity of Enicostemma littorale(E.littorale) using different solvents.Methods:Chloroform,methanol and acetone extracts of different parts of E.littorale(leaf,stem and root) were ...Objective:To study the antimicrobial activity of Enicostemma littorale(E.littorale) using different solvents.Methods:Chloroform,methanol and acetone extracts of different parts of E.littorale(leaf,stem and root) were evaluated for antimicrobial activity using disc diffusion method against some gram-negative species such as Escherichia coli,Klebsiella pnemoniae, Pseudomonas aeruginosa,Salmonella typhi and gram-positive species Staphylococcus aureus, Bacillus cereus,Bacillus subtilis and two fugal species viz.,Aspergillus fumigates and Aspergillus flavus.Results:The chloroform extracts showed the highest antibacterial activity.Among leaf, stem and root extracts,the stem extracts showed maximum antibacterial activity.All of the used extracts had no significant antifungal activity against Aspergillus fumigates and Aspergillus flavus.The chloroform stem extract showed highest activity(about 20 mm inhibition zone) against Bacillus subtilis(at 500 tng/mL) followed by the methanolic stem extract which showed highest activity against the same organism.The lowest antibacterial activity was observed by the acetone leaf extract(about 8 mm inhibition zone) against Escherichia coli.Conclusions:The findings of the study indicate littorale could also be a new source for antibiotics discovery.展开更多
Traditional medicine system of India comprised varieties of plants which are playing a significant role in curing diseases from ancient times.Among them,Enicostemma littorale blume(E.littorale)a perennial herb of the ...Traditional medicine system of India comprised varieties of plants which are playing a significant role in curing diseases from ancient times.Among them,Enicostemma littorale blume(E.littorale)a perennial herb of the family Gentianaceae is cosmopolitan in occurrence in India.The bittery natured plant acts as a laxative,helps in curing fever,rheumatism,skin diseases,abdominal disorders,snake bite,obesity and helps to regulate blood sugar levels.The plant constituents have been reported for possessing antimicrobial,antioxidant,antiulcer,antiinflammatory,hypolipidaemic,hepatoprotective and hypoglycemic properties.This review provides a bird's eye view about geographical distribution,physicochemical parameters,phvtoconstituents and pharmacological properties of E.littorale.展开更多
基金finacially supported by Department of Science and Technologypart of project work under "Innovation in Scientific Pursuit for Inspired Research programme"(INSPIRE)Department of Science and Technology(DST),Government of India,New Delhi awarded to the first author
文摘Objective:To study the antimicrobial activity of Enicostemma littorale(E.littorale) using different solvents.Methods:Chloroform,methanol and acetone extracts of different parts of E.littorale(leaf,stem and root) were evaluated for antimicrobial activity using disc diffusion method against some gram-negative species such as Escherichia coli,Klebsiella pnemoniae, Pseudomonas aeruginosa,Salmonella typhi and gram-positive species Staphylococcus aureus, Bacillus cereus,Bacillus subtilis and two fugal species viz.,Aspergillus fumigates and Aspergillus flavus.Results:The chloroform extracts showed the highest antibacterial activity.Among leaf, stem and root extracts,the stem extracts showed maximum antibacterial activity.All of the used extracts had no significant antifungal activity against Aspergillus fumigates and Aspergillus flavus.The chloroform stem extract showed highest activity(about 20 mm inhibition zone) against Bacillus subtilis(at 500 tng/mL) followed by the methanolic stem extract which showed highest activity against the same organism.The lowest antibacterial activity was observed by the acetone leaf extract(about 8 mm inhibition zone) against Escherichia coli.Conclusions:The findings of the study indicate littorale could also be a new source for antibiotics discovery.
文摘Traditional medicine system of India comprised varieties of plants which are playing a significant role in curing diseases from ancient times.Among them,Enicostemma littorale blume(E.littorale)a perennial herb of the family Gentianaceae is cosmopolitan in occurrence in India.The bittery natured plant acts as a laxative,helps in curing fever,rheumatism,skin diseases,abdominal disorders,snake bite,obesity and helps to regulate blood sugar levels.The plant constituents have been reported for possessing antimicrobial,antioxidant,antiulcer,antiinflammatory,hypolipidaemic,hepatoprotective and hypoglycemic properties.This review provides a bird's eye view about geographical distribution,physicochemical parameters,phvtoconstituents and pharmacological properties of E.littorale.
