The clear,tranquil,turquoise-colored Chixiang Tso Lake lies in a picturesque land.About noon,the sunlight sparkles on the lake.One of the vehicles' coming to a stop inside the government compound of Barling Town,w...The clear,tranquil,turquoise-colored Chixiang Tso Lake lies in a picturesque land.About noon,the sunlight sparkles on the lake.One of the vehicles' coming to a stop inside the government compound of Barling Town,we finally feel comforted by observing the serene and blue-colored lake.After half a day of traveling,at last we can relax.展开更多
In this paper,the local fractional natural decomposition method(LFNDM)is used for solving a local fractional Poisson equation.The local fractional Poisson equation plays a significant role in the study of a potential ...In this paper,the local fractional natural decomposition method(LFNDM)is used for solving a local fractional Poisson equation.The local fractional Poisson equation plays a significant role in the study of a potential field due to a fixed electric charge or mass density distribution.Numerical examples with computer simulations are presented in this paper.The obtained results show that LFNDM is effective and convenient for application.展开更多
To combine localized drug release with multimodal therapy for malignant tumor, a composite hydrogel as an integrative drug delivery system was facilely prepared. The system contains spinach extract （SE）, reduced gra...To combine localized drug release with multimodal therapy for malignant tumor, a composite hydrogel as an integrative drug delivery system was facilely prepared. The system contains spinach extract （SE）, reduced graphene oxide （rGO） and gold nanocages （AuNCs）. SE conduces to the formation of hydrogel, and also serves as a green material for improving the biocompatibility of hydrogel, and a natural pho- tosensitizer for killing tumor cells under laser radiation （fi60 nm）. AuNts show obvious photothermy and can enhance the generation of cytotoxic singlet oxygen （102）. The composite hydrogel shell on tumor cells exhibits several competitive advantages including enhanced antitumor effect by retaining the high con- centration of drugs around cancer cell, excellent PDT/FFr compatibility as well as high loading and controllable release of fluorouracil （5-FU） for synergetic multimodal treatment. The survival rate of HeLa cells incubated with 5-FU loaded hydrogel under NIR radiation for 10 min sharply decreases to 1.2%, in- dicating remarkably improved antitumor effects. These results demonstrate that the hydrogel is an excellent delivery carrier for localizable, NIR-responsive and combined PTT/PDT/Chemo synergetic antitumor.展开更多
文摘The clear,tranquil,turquoise-colored Chixiang Tso Lake lies in a picturesque land.About noon,the sunlight sparkles on the lake.One of the vehicles' coming to a stop inside the government compound of Barling Town,we finally feel comforted by observing the serene and blue-colored lake.After half a day of traveling,at last we can relax.
文摘In this paper,the local fractional natural decomposition method(LFNDM)is used for solving a local fractional Poisson equation.The local fractional Poisson equation plays a significant role in the study of a potential field due to a fixed electric charge or mass density distribution.Numerical examples with computer simulations are presented in this paper.The obtained results show that LFNDM is effective and convenient for application.
基金supported by the National Natural Science Foundation of China (Nos. 21171001, 51372004, 21571002 and 21371003)the Anhui Province Key Laboratory of Environmentfriendly Polymer Materials+1 种基金the Anhui Provincial College Student Innovation Fund Project (No. 201510375048)Key Project of the Natural Science Foundation of the Provincial Education Department (No. KJ2016A679)
文摘To combine localized drug release with multimodal therapy for malignant tumor, a composite hydrogel as an integrative drug delivery system was facilely prepared. The system contains spinach extract （SE）, reduced graphene oxide （rGO） and gold nanocages （AuNCs）. SE conduces to the formation of hydrogel, and also serves as a green material for improving the biocompatibility of hydrogel, and a natural pho- tosensitizer for killing tumor cells under laser radiation （fi60 nm）. AuNts show obvious photothermy and can enhance the generation of cytotoxic singlet oxygen （102）. The composite hydrogel shell on tumor cells exhibits several competitive advantages including enhanced antitumor effect by retaining the high con- centration of drugs around cancer cell, excellent PDT/FFr compatibility as well as high loading and controllable release of fluorouracil （5-FU） for synergetic multimodal treatment. The survival rate of HeLa cells incubated with 5-FU loaded hydrogel under NIR radiation for 10 min sharply decreases to 1.2%, in- dicating remarkably improved antitumor effects. These results demonstrate that the hydrogel is an excellent delivery carrier for localizable, NIR-responsive and combined PTT/PDT/Chemo synergetic antitumor.
