Earthquake has a significant impact on operation safety of the high speed railway,and for Jakarta-Bandung High Speed Railway(HSR)in Indonesia where it is earthquake-prone,it is necessary to establish an earthquake ear...Earthquake has a significant impact on operation safety of the high speed railway,and for Jakarta-Bandung High Speed Railway(HSR)in Indonesia where it is earthquake-prone,it is necessary to establish an earthquake early warning system to strengthen its earthquake resistance.Based on the principle and technical characteristics of China's high speed railway earthquake early warning system and combining the actual situations of Jakarta-Bandung HSR in Indonesia,this paper describes how to implement China's high speed railway earthquake early warning system in Jakarta-Bandung HSR.It focuses on optimizations in environmental adaptation design and seismic network interface design,earthquake attenuation model parameter adjustment and terminal software interface adjustment,so as to make the system better suit the local situations,and meet operation requirements and guarantee safe operation of Jakarta-Bandung HSR.展开更多
Jakarta-Bandung HSR in Indonesia is the first“go global”project of China's high speed railway with a whole system,all elements and a whole industry chain,as well as the first overseas project adopting a complete...Jakarta-Bandung HSR in Indonesia is the first“go global”project of China's high speed railway with a whole system,all elements and a whole industry chain,as well as the first overseas project adopting a complete set of Chinese standards.This paper sorts out the differences between relevant standards in China and Indonesia,including those in concrete raw materials,rebar standards and other main material standards,and those in external interface standards,train operation direction requirements,project approval requirements,special acceptance requirements,etc.,and summarizes the realization methods and specific achievements of localized application of Chinese standards during the implementation of Jakarta-Bandung HSR Project,to provide reference for localized application of Chinese standards in overseas projects in the future.展开更多
Periodontitis is an inflammatory autoimmune disease. Treatment should alleviate inflammation, regulate the immune reaction and promote periodontal tissue regeneration. Icariin is the main active ingredient of Epimedii...Periodontitis is an inflammatory autoimmune disease. Treatment should alleviate inflammation, regulate the immune reaction and promote periodontal tissue regeneration. Icariin is the main active ingredient of Epimedii Folium, and it is a promising compound for the enhancement of mesenchymal stem cell function, promotion of bone formation, inhibition of bone resorption, alleviation of inflammation and regulation of immunity. The study investigated the effect of icariin on periodontal tissue regeneration in a minipig model of periodontitis. The minipig model of periodontitis was established. Icariin was injected locally. The periodontal clinical assessment index, a computed tomography(CT) scan, histopathology and enzyme-linked immune sorbent assay(ELISA)were used to evaluate the effects of icariin. Quantitative analysis results 12 weeks post-injection demonstrated that probing depth,gingival recession, attachment loss and alveolar bone regeneration values were(3.72 ± 1.18) mm vs.(6.56 ± 1.47) mm,(1.67 ± 0.59)mm vs.(2.38 ± 0.61) mm,(5.56 ± 1.29) mm vs.(8.61 ± 1.72) mm, and(25.65 ± 5.13) mm3 vs.(9.48 ± 1.78) mm3 in the icariin group and0.9% NaCl group, respectively. The clinical assessment, CT scan, and histopathology results demonstrated significant enhancement of periodontal tissue regeneration in the icariin group compared to the 0.9% NaCl group. The ELISA results suggested that the concentration of interleukin-1 beta(IL-1β) in the icariin group was downregulated compared to the 0.9% NaCl group, which indicates that local injection of icariin relieved local inflammation in a minipig model of periodontitis. Local injection of icariin promoted periodontal tissue regeneration and exerted anti-inflammatory and immunomodulatory function. These results support the application of icariin for the clinical treatment of periodontitis.展开更多
文摘Earthquake has a significant impact on operation safety of the high speed railway,and for Jakarta-Bandung High Speed Railway(HSR)in Indonesia where it is earthquake-prone,it is necessary to establish an earthquake early warning system to strengthen its earthquake resistance.Based on the principle and technical characteristics of China's high speed railway earthquake early warning system and combining the actual situations of Jakarta-Bandung HSR in Indonesia,this paper describes how to implement China's high speed railway earthquake early warning system in Jakarta-Bandung HSR.It focuses on optimizations in environmental adaptation design and seismic network interface design,earthquake attenuation model parameter adjustment and terminal software interface adjustment,so as to make the system better suit the local situations,and meet operation requirements and guarantee safe operation of Jakarta-Bandung HSR.
文摘Jakarta-Bandung HSR in Indonesia is the first“go global”project of China's high speed railway with a whole system,all elements and a whole industry chain,as well as the first overseas project adopting a complete set of Chinese standards.This paper sorts out the differences between relevant standards in China and Indonesia,including those in concrete raw materials,rebar standards and other main material standards,and those in external interface standards,train operation direction requirements,project approval requirements,special acceptance requirements,etc.,and summarizes the realization methods and specific achievements of localized application of Chinese standards during the implementation of Jakarta-Bandung HSR Project,to provide reference for localized application of Chinese standards in overseas projects in the future.
基金supported by grants from the National Natural Science Foundation of China (grant number 81625005 to Z.F.)High-level Talents of the Beijing Health System (grant number 2014-3-080 to F.Z.)the program for Beijing Science and Technology of Chinese Medicine (grant number JJ2013-11 to F.Z.)
文摘Periodontitis is an inflammatory autoimmune disease. Treatment should alleviate inflammation, regulate the immune reaction and promote periodontal tissue regeneration. Icariin is the main active ingredient of Epimedii Folium, and it is a promising compound for the enhancement of mesenchymal stem cell function, promotion of bone formation, inhibition of bone resorption, alleviation of inflammation and regulation of immunity. The study investigated the effect of icariin on periodontal tissue regeneration in a minipig model of periodontitis. The minipig model of periodontitis was established. Icariin was injected locally. The periodontal clinical assessment index, a computed tomography(CT) scan, histopathology and enzyme-linked immune sorbent assay(ELISA)were used to evaluate the effects of icariin. Quantitative analysis results 12 weeks post-injection demonstrated that probing depth,gingival recession, attachment loss and alveolar bone regeneration values were(3.72 ± 1.18) mm vs.(6.56 ± 1.47) mm,(1.67 ± 0.59)mm vs.(2.38 ± 0.61) mm,(5.56 ± 1.29) mm vs.(8.61 ± 1.72) mm, and(25.65 ± 5.13) mm3 vs.(9.48 ± 1.78) mm3 in the icariin group and0.9% NaCl group, respectively. The clinical assessment, CT scan, and histopathology results demonstrated significant enhancement of periodontal tissue regeneration in the icariin group compared to the 0.9% NaCl group. The ELISA results suggested that the concentration of interleukin-1 beta(IL-1β) in the icariin group was downregulated compared to the 0.9% NaCl group, which indicates that local injection of icariin relieved local inflammation in a minipig model of periodontitis. Local injection of icariin promoted periodontal tissue regeneration and exerted anti-inflammatory and immunomodulatory function. These results support the application of icariin for the clinical treatment of periodontitis.
