Artificial nanomotors are nanoscale machines capable of converting surrounding other energy into mechanical motion and thus entering the tissues and cells of organisms.They hold great potential to revolutionize the di...Artificial nanomotors are nanoscale machines capable of converting surrounding other energy into mechanical motion and thus entering the tissues and cells of organisms.They hold great potential to revolutionize the diagnosis and treatment of diseases by actively targeting the lesion location,though there are many new challenges that arise with decreasing the size to nanoscale.This review sum-marizes and comments on the state-of-the-art artificial nanomotors with ad-vantages and limitations.It starts with the fabrication methods,including common physical vapor deposition and colloidal chemistry methods,followed by the locomotion characterization and motion manipulation.Then,the in vitro and in vivo biomedical applications are introduced in detail.The challenges and future prospects are discussed at the end.展开更多
基金This study was financially supported by the National Natural Science Foundation of China(22075222,21705123,and 51521001)the National Key R&D Program of China(2021YFA1201400).
文摘Artificial nanomotors are nanoscale machines capable of converting surrounding other energy into mechanical motion and thus entering the tissues and cells of organisms.They hold great potential to revolutionize the diagnosis and treatment of diseases by actively targeting the lesion location,though there are many new challenges that arise with decreasing the size to nanoscale.This review sum-marizes and comments on the state-of-the-art artificial nanomotors with ad-vantages and limitations.It starts with the fabrication methods,including common physical vapor deposition and colloidal chemistry methods,followed by the locomotion characterization and motion manipulation.Then,the in vitro and in vivo biomedical applications are introduced in detail.The challenges and future prospects are discussed at the end.
