AIM:To investigate the efficiency of Cox proportional hazard model in detecting prognostic factors for gastric cancer.METHODS:We used the log-normal regression model to evaluate prognostic factors in gastric cancer an...AIM:To investigate the efficiency of Cox proportional hazard model in detecting prognostic factors for gastric cancer.METHODS:We used the log-normal regression model to evaluate prognostic factors in gastric cancer and compared it with the Cox model.Three thousand and eighteen gastric cancer patients who received a gastrectomy between 1980 and 2004 were retrospectively evaluated.Clinic-pathological factors were included in a log-normal model as well as Cox model.The akaike information criterion (AIC) was employed to compare the efficiency of both models.Univariate analysis indicated that age at diagnosis,past history,cancer location,distant metastasis status,surgical curative degree,combined other organ resection,Borrmann type,Lauren's classification,pT stage,total dissected nodes and pN stage were prognostic factors in both log-normal and Cox models.RESULTS:In the final multivariate model,age at diagnosis,past history,surgical curative degree,Borrmann type,Lauren's classification,pT stage,and pN stage were significant prognostic factors in both log-normal and Cox models.However,cancer location,distant metastasis status,and histology types were found to be significant prognostic factors in log-normal results alone.According to AIC,the log-normal model performed better than the Cox proportional hazard model (AIC value:2534.72 vs 1693.56).CONCLUSION:It is suggested that the log-normal regression model can be a useful statistical model to evaluate prognostic factors instead of the Cox proportional hazard model.展开更多
During the process of coal prospecting and exploration, different measurement time, different logging instruments and series can lead to systematic errors in well logs. Accordingly, all logging curves need to be norma...During the process of coal prospecting and exploration, different measurement time, different logging instruments and series can lead to systematic errors in well logs. Accordingly, all logging curves need to be normalized in the mining area. By studying well-logging normalization methods, and focusing on the characteristics of the coalfield, the frequency histogram method was used in accordance with the condition of the Guqiao Coal Mine. In this way, the density and sonic velocity at marker bed in the non-key well were made to close to those in the key well, and were eventually equal. Well log normalization was completed when this method was applied to the entire logging curves. The results show that the scales of logging data were unified by normalizing coal logging curves, and the logging data were consistent with wave impedance inversion data. A satisfactory inversion effect was obtained.展开更多
Modeling time headways between vehicles has attracted increasing interest in the traffic flow research field recently, because the corresponding statistics help to reveal the intrinsic interactions governing the vehic...Modeling time headways between vehicles has attracted increasing interest in the traffic flow research field recently, because the corresponding statistics help to reveal the intrinsic interactions governing the vehicle dynamics. However, most previous micro-simulation models cannot yield the observed log-normal distributed headways. This paper designs a new car-following model inspired by the Galton board to reproduce the observed time-headway distributions as well as the complex traffic phenomena. The consistency between the empirical data and the simulation results indicates that this new car-following model provides a reasonable description of the car-following behaviours.展开更多
Due to differences in the distribution of scores for different trials, the performance of a speaker verification system will be seriously diminished if raw scores are directly used for detection with a unified thresho...Due to differences in the distribution of scores for different trials, the performance of a speaker verification system will be seriously diminished if raw scores are directly used for detection with a unified threshold value. As such, the scores must be normalized. To tackle the shortcomings of score normalization methods, we propose a speaker verification system based on log-likelihood normalization (LLN). Without a priori knowledge, LLN increases the separation between scores of target and non-target speaker models, so as to improve score aliasing of “same-speaker” and “different-speaker” trials corresponding to the same test speech, enabling better discrimination and decision capability. The experiment shows that LLN is an effective method of scoring normalization.展开更多
In this paper, we study the connectivity of multihop wireless networks under the log-normal shadowing model by investigating the precise distribution of the number of isolated nodes. Under such a realistic shadowing m...In this paper, we study the connectivity of multihop wireless networks under the log-normal shadowing model by investigating the precise distribution of the number of isolated nodes. Under such a realistic shadowing model, all previous known works on the distribution of the number of isolated nodes were obtained only based on simulation studies or by ignoring the important boundary effect to avoid the challenging technical analysis, and thus cannot be applied to any practical wireless networks. It is extremely challenging to take the complicated boundary effect into consideration under such a realistic model because the transmission area of each node is an irregular region other than a circular area. Assume that the wireless nodes are represented by a Poisson point process with densitynover a unit-area disk, and that the transmission power is properly chosen so that the expected node degree of the network equals lnn + ξ (n), where ξ (n) approaches to a constant ξ as n →?∞. Under such a shadowing model with the boundary effect taken into consideration, we proved that the total number of isolated nodes is asymptotically Poisson with mean e$ {-ξ}. The Brun’s sieve is utilized to derive the precise asymptotic distribution. Our results can be used as design guidelines for any practical multihop wireless network where both the shadowing and boundary effects must be taken into consideration.展开更多
In this paper, we propose a log-normal linear model whose errors are first-order correlated, and suggest a two-stage method for the efficient estimation of the conditional mean of the response variable at the original...In this paper, we propose a log-normal linear model whose errors are first-order correlated, and suggest a two-stage method for the efficient estimation of the conditional mean of the response variable at the original scale. We obtain two estimators which minimize the asymptotic mean squared error （MM） and the asymptotic bias （MB）, respectively. Both the estimators are very easy to implement, and simulation studies show that they are perform better.展开更多
We have observed weather clutter containing targets (ships) using an S-band radar with a frequency 3.05 GHz, a beam width 1.8°, and a pulsewidth 0.5 μs. To investigate the weather clutter amplitude statistics, w...We have observed weather clutter containing targets (ships) using an S-band radar with a frequency 3.05 GHz, a beam width 1.8°, and a pulsewidth 0.5 μs. To investigate the weather clutter amplitude statistics, we introduce the Akaike Information Criterion (AIC). We have found that the weather clutter amplitudes obey the log-normal, Weibull, and log-Weibull distributions with the shape parameters of 0.308 to 0.470, 4.42 to 4.51, and 15.91 to 16.44, respectively, for small data within the beam width of an antenna. We have proposed the log-normal/CFAR circuit modified a Cell-Averaging (CA) LOG/CFAR circuit. It is found that weather clutter is suppressed with improvement of 51.58 dB by log-normal/CFAR. As a result, we have showed that weather clutter observed by S-band radar does not obey the Rayleigh distribution and our log-normal/CFAR circuit has an effect on suppression of clutter and detection of target, while conventional LOG/CFAR circuit does not. In addition, if our circuit can be realized, we will have an advantage economically.展开更多
Medical research data are often skewed and heteroscedastic. It has therefore become practice to log-transform data in regression analysis, in order to stabilize the variance. Regression analysis on log-transformed dat...Medical research data are often skewed and heteroscedastic. It has therefore become practice to log-transform data in regression analysis, in order to stabilize the variance. Regression analysis on log-transformed data estimates the relative effect, whereas it is often the absolute effect of a predictor that is of interest. We propose a maximum likelihood (ML)-based approach to estimate a linear regression model on log-normal, heteroscedastic data. The new method was evaluated with a large simulation study. Log-normal observations were generated according to the simulation models and parameters were estimated using the new ML method, ordinary least-squares regression (LS) and weighed least-squares regression (WLS). All three methods produced unbiased estimates of parameters and expected response, and ML and WLS yielded smaller standard errors than LS. The approximate normality of the Wald statistic, used for tests of the ML estimates, in most situations produced correct type I error risk. Only ML and WLS produced correct confidence intervals for the estimated expected value. ML had the highest power for tests regarding β1.展开更多
基金Supported by the Gastric Cancer Laboratory and Pathology Department of Chinese Medical University,Shenyang,Chinathe Science and Technology Program of Shenyang,No. 1081232-1-00
文摘AIM:To investigate the efficiency of Cox proportional hazard model in detecting prognostic factors for gastric cancer.METHODS:We used the log-normal regression model to evaluate prognostic factors in gastric cancer and compared it with the Cox model.Three thousand and eighteen gastric cancer patients who received a gastrectomy between 1980 and 2004 were retrospectively evaluated.Clinic-pathological factors were included in a log-normal model as well as Cox model.The akaike information criterion (AIC) was employed to compare the efficiency of both models.Univariate analysis indicated that age at diagnosis,past history,cancer location,distant metastasis status,surgical curative degree,combined other organ resection,Borrmann type,Lauren's classification,pT stage,total dissected nodes and pN stage were prognostic factors in both log-normal and Cox models.RESULTS:In the final multivariate model,age at diagnosis,past history,surgical curative degree,Borrmann type,Lauren's classification,pT stage,and pN stage were significant prognostic factors in both log-normal and Cox models.However,cancer location,distant metastasis status,and histology types were found to be significant prognostic factors in log-normal results alone.According to AIC,the log-normal model performed better than the Cox proportional hazard model (AIC value:2534.72 vs 1693.56).CONCLUSION:It is suggested that the log-normal regression model can be a useful statistical model to evaluate prognostic factors instead of the Cox proportional hazard model.
基金Supported by the National Basic Research Program of China （2009CB219603, 2010CB226800） the National Natural Science Foundation of China （40874071, 40672104）
文摘During the process of coal prospecting and exploration, different measurement time, different logging instruments and series can lead to systematic errors in well logs. Accordingly, all logging curves need to be normalized in the mining area. By studying well-logging normalization methods, and focusing on the characteristics of the coalfield, the frequency histogram method was used in accordance with the condition of the Guqiao Coal Mine. In this way, the density and sonic velocity at marker bed in the non-key well were made to close to those in the key well, and were eventually equal. Well log normalization was completed when this method was applied to the entire logging curves. The results show that the scales of logging data were unified by normalizing coal logging curves, and the logging data were consistent with wave impedance inversion data. A satisfactory inversion effect was obtained.
基金supported partly by the National Basic Research Program of China (Grant No. 2006CB705506)the National Hi-Tech Research and Development Program of China (Grant Nos. 2006AA11Z215 and 2007AA11Z222)the National Natural Science Foundation of China (Grant Nos. 50708055, 60774034 and 10872194)
文摘Modeling time headways between vehicles has attracted increasing interest in the traffic flow research field recently, because the corresponding statistics help to reveal the intrinsic interactions governing the vehicle dynamics. However, most previous micro-simulation models cannot yield the observed log-normal distributed headways. This paper designs a new car-following model inspired by the Galton board to reproduce the observed time-headway distributions as well as the complex traffic phenomena. The consistency between the empirical data and the simulation results indicates that this new car-following model provides a reasonable description of the car-following behaviours.
文摘Due to differences in the distribution of scores for different trials, the performance of a speaker verification system will be seriously diminished if raw scores are directly used for detection with a unified threshold value. As such, the scores must be normalized. To tackle the shortcomings of score normalization methods, we propose a speaker verification system based on log-likelihood normalization (LLN). Without a priori knowledge, LLN increases the separation between scores of target and non-target speaker models, so as to improve score aliasing of “same-speaker” and “different-speaker” trials corresponding to the same test speech, enabling better discrimination and decision capability. The experiment shows that LLN is an effective method of scoring normalization.
文摘In this paper, we study the connectivity of multihop wireless networks under the log-normal shadowing model by investigating the precise distribution of the number of isolated nodes. Under such a realistic shadowing model, all previous known works on the distribution of the number of isolated nodes were obtained only based on simulation studies or by ignoring the important boundary effect to avoid the challenging technical analysis, and thus cannot be applied to any practical wireless networks. It is extremely challenging to take the complicated boundary effect into consideration under such a realistic model because the transmission area of each node is an irregular region other than a circular area. Assume that the wireless nodes are represented by a Poisson point process with densitynover a unit-area disk, and that the transmission power is properly chosen so that the expected node degree of the network equals lnn + ξ (n), where ξ (n) approaches to a constant ξ as n →?∞. Under such a shadowing model with the boundary effect taken into consideration, we proved that the total number of isolated nodes is asymptotically Poisson with mean e$ {-ξ}. The Brun’s sieve is utilized to derive the precise asymptotic distribution. Our results can be used as design guidelines for any practical multihop wireless network where both the shadowing and boundary effects must be taken into consideration.
基金The NSF(11271155) of ChinaResearch Fund(20070183023) for the Doctoral Program of Higher Education
文摘In this paper, we propose a log-normal linear model whose errors are first-order correlated, and suggest a two-stage method for the efficient estimation of the conditional mean of the response variable at the original scale. We obtain two estimators which minimize the asymptotic mean squared error （MM） and the asymptotic bias （MB）, respectively. Both the estimators are very easy to implement, and simulation studies show that they are perform better.
文摘We have observed weather clutter containing targets (ships) using an S-band radar with a frequency 3.05 GHz, a beam width 1.8°, and a pulsewidth 0.5 μs. To investigate the weather clutter amplitude statistics, we introduce the Akaike Information Criterion (AIC). We have found that the weather clutter amplitudes obey the log-normal, Weibull, and log-Weibull distributions with the shape parameters of 0.308 to 0.470, 4.42 to 4.51, and 15.91 to 16.44, respectively, for small data within the beam width of an antenna. We have proposed the log-normal/CFAR circuit modified a Cell-Averaging (CA) LOG/CFAR circuit. It is found that weather clutter is suppressed with improvement of 51.58 dB by log-normal/CFAR. As a result, we have showed that weather clutter observed by S-band radar does not obey the Rayleigh distribution and our log-normal/CFAR circuit has an effect on suppression of clutter and detection of target, while conventional LOG/CFAR circuit does not. In addition, if our circuit can be realized, we will have an advantage economically.
文摘Medical research data are often skewed and heteroscedastic. It has therefore become practice to log-transform data in regression analysis, in order to stabilize the variance. Regression analysis on log-transformed data estimates the relative effect, whereas it is often the absolute effect of a predictor that is of interest. We propose a maximum likelihood (ML)-based approach to estimate a linear regression model on log-normal, heteroscedastic data. The new method was evaluated with a large simulation study. Log-normal observations were generated according to the simulation models and parameters were estimated using the new ML method, ordinary least-squares regression (LS) and weighed least-squares regression (WLS). All three methods produced unbiased estimates of parameters and expected response, and ML and WLS yielded smaller standard errors than LS. The approximate normality of the Wald statistic, used for tests of the ML estimates, in most situations produced correct type I error risk. Only ML and WLS produced correct confidence intervals for the estimated expected value. ML had the highest power for tests regarding β1.
基金Supported by the National Natural Science Foundation of China(12171335,12301603)the Science Development Project of Sichuan University(2020SCUNL201)the Scientific Foundation of Nanjing University of Posts and Telecommunications(NY221026)。
