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Breaking out from the neuroprotective logjam:combined treatment with remote ischemic conditioning and minocycline in the prehospital setting
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作者 Jung Mi Park David C.Hess 《Neural Regeneration Research》 SCIE CAS CSCD 2015年第4期537-539,共3页
The only two treatments effective for acute ischemic stroke are reperfusion therapies. Despite testing of hundreds of neuroprotective agents and treatments, tissue plasminogen activator (tPA), approved by the Food a... The only two treatments effective for acute ischemic stroke are reperfusion therapies. Despite testing of hundreds of neuroprotective agents and treatments, tissue plasminogen activator (tPA), approved by the Food and Drug Administration (FDA) in 1996, remains the only FDA-approved drug for the treatment of ischemic stroke. Recently, 展开更多
关键词 Breaking out from the neuroprotective logjam RIC
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Effects of logjams on river hydrodynamics under inundation conditions
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作者 Huai-jian Bao Ping Wang +2 位作者 Wei-jie Wang Yu-yan Liu Tian-jiao Feng 《Journal of Hydrodynamics》 SCIE EI 2024年第4期757-771,共15页
Large wood in rivers can lead to accumulations in the river channel, affecting local flow structures, aquatic habitats, and the river’s topography. This plays a crucial role in the ecological restoration of the river... Large wood in rivers can lead to accumulations in the river channel, affecting local flow structures, aquatic habitats, and the river’s topography. This plays a crucial role in the ecological restoration of the river. This paper presents flow field measurements downstream of six types of logjams at different flow velocities using acoustic Doppler velocimetry (ADV) for artificially designed engineered logjams. The results indicate that the presence of logjams reduces the flow velocity and increases the turbulent kinetic energy in the wake region, and as the distance downstream increases, the flow velocity and turbulence intensity in the wake region gradually return to the upstream level. The minimum values of normalized flow velocity under different conditions are located in the region of the bottommost logs. The differences in normalized flow velocity at various flow rates are not significant. Jets are less likely to be generated in logjams with larger and more concentrated projection areas, but the strength of the jet is influenced by the physical structure of the logjam (projection area, gap ratio). The flow distribution behind the logjam is primarily influenced by the proportion of the projected area in different regions. Changes in the vertical physical structure of the logjam have minimal effect on the lateral flow distribution. Flow velocity in the gap area (b0) at the bottom of different logjams is influenced by their physical structure. The larger the overall blockage area of the logjams, the larger the flow velocity in the bottom gap area will be. The flow velocity in the bottom gap area of a densely placed logjam is mainly influenced by the gap ratio. The velocity of flow in the gap area can impact the initiation and deposition of sediment near the logjam. However, the internal structure complexity of the logjam does not significantly affect river energy dissipation and flow attenuation. This study broadens the applicability of certain theoretical models and explores the impact of logjams on river ecology and channel geomorphology. The findings can serve as a theoretical foundation for ecological restoration, timber management, and logjam construction in rivers. 展开更多
关键词 Open channel flow engineered logjams nonuniform logs flow structure river ecological restoration
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漂木对山洪泥石流运动致灾影响研究进展 被引量:2
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作者 陈剑刚 费高高 +2 位作者 王喜安 陈华勇 陈晓清 《水利水电科技进展》 CSCD 北大核心 2022年第3期104-111,共8页
基于国内外研究现状,对漂木的补给、搬运堆积、聚集堵塞、溃决等动力过程进行了详细评述,总结出山洪泥石流中漂木致灾效应包括冲击破坏、堵塞淹没、堵塞冲刷、溃决冲刷4个方面,并着重阐述了现有研究的不足。为应对漂木致灾效应,提出工... 基于国内外研究现状,对漂木的补给、搬运堆积、聚集堵塞、溃决等动力过程进行了详细评述,总结出山洪泥石流中漂木致灾效应包括冲击破坏、堵塞淹没、堵塞冲刷、溃决冲刷4个方面,并着重阐述了现有研究的不足。为应对漂木致灾效应,提出工程措施与管理措施相结合的漂木防灾减灾措施。在此基础上,指出未来研究的主题包括:漂木补给定量评估、漂木运动停积堵塞溃决动力过程、漂木致灾效应与风险评估、漂木灾害调控与减灾措施。 展开更多
关键词 山洪 泥石流 漂木 堵塞 溃决放大
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