The Effect of Breathing Route on Heart Rate Variability—A within Subject Comparative Study

Background: The effect of traffic related emissions on Heart Rate Variability (HRV) has been previously demonstrated. However, the results of different studies on the relationship between ambient pollutants and specifically carbon monoxide (CO) on HRV are inconclusive and appear to reflect personal differences. The differences in methodology including breathing style and participants under study can possibly attribute to this variability. The aim of the present study is to assess the effect of the breathing route (Nasal/Oral) on the relationship between CO concentration and HRV. Methodology: Forty healthy participants (25 females, 15 males) between the ages of 15 - 50 years were included in the study. The participants strolled in a central bus station, staying for 10 minutes in three designated locations alternating nasal and oral breathing. CO concentration and HRV were continuously monitored. Frequency (LnLF, LnHF, LnLF/HF) and time domain (LnSDNN, LnRMSSD) HRV indices were computed. Analysis: MANCOVA, with HRV indices being the dependent variables and CO, gender and age being the independent variables was employed. Results: Significant interaction effects between breathing route and CO, and breathing route and gender on HRV (LnLF/HF) were found (p = 0.04 and 0.01 respectively). Both CO and age were found to affect LnSDNN and LnRMSSD. Conclusion: Breathing route emerges as a possible modifier of the relationship between air pollution and HRV and thus contributes to interpersonal differences obtained in studies investigating the effect of environmental pollution and HRV.

39例抑郁症患者短程心率变异性临床分析

[背景]探讨抑郁症患者的植物神经功能特点.[病例报告]对39例中、重度抑郁症患者及41例健康对照者进行短程心率变异性(HRV)频谱分析,对获得的HRV指标进行比较.与健康对照组比较,抑郁症组HRV时域指标及频域指标均明显下降,尤以交感/副交感平衡指标(LF/HF)降低明显(P<0.05).[讨论]抑郁症患者植物神经功能下降,副交感神经兴奋性升高,引起交感神经和副交感神经平衡失常.

短程心率变异与长程心率变异对比分析

目的 探讨短程心率变异在临床应用的价值。方法 短程心率变异性测试采用床旁一分钟的测试方法 ,即受测试者佩带Holter记录盒后立即卧床 ,深呼吸 ,用心电图机连续描记一分钟的心电图 ,测试RR间期 ,如果RR间期所对应的快慢心率相差 10次以上为正常 ,低于或等于 10次为异常。结果 (1)正常人短程心率变异性与高血压冠心病患者短程心率变异有显著差异 ;(2 )正常人长程心率变异时域指标分析与唐海沁等健康人心率变异时域法正常值分析结果相符 ;(3)短程与长程心率变异异常发生率无显著性差异 (P >0 0 5 )。

短程心率变异性的临床应用

目的探讨短程心率变异的临床应用价值。方法测定高血压冠心病病人和正常对照组短程和长程心率变异的时域指标，并进行比较分析。短程心率变异性测试采用床边1min的测试方法，即受测试者佩带24h动态心电监测（Holter）记录盒后立即卧床，深呼吸，用心电图机连续描记1min的心电图。测试RR间期，如果RR间期所对应的快慢心率相差10次以上为正常，≤10次为异常。结果正常人短程心率变异性与高血压冠心病患者短程心率变异差异有统计学意义；短程和长程心率变异异常发生率差异无统计学意义；正常人短程心率变异与长程心率变异缺乏对比性。结论短程HRV有一定的临床应用价值意义。