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Superwetting Ag/α-Fe_(2)O_(3) anchored mesh with enhanced photocatalytic and antibacterial activities for efficient water purification 被引量:1
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作者 Jiakai Li Changpeng Lv +5 位作者 Jiajia Song Xiaoling Zhang Xizhen Huang Yingzhuo Ma Haijie Cao Na Liu 《Green Energy & Environment》 SCIE EI CAS CSCD 2024年第1期89-103,共15页
Superwetting materials have drawn unprecedented attention in the treatment of oily wastewater due to their preferable anti-fouling property and selective oil/water separation.However,it is still a challenge to fabrica... Superwetting materials have drawn unprecedented attention in the treatment of oily wastewater due to their preferable anti-fouling property and selective oil/water separation.However,it is still a challenge to fabricate multifunctional and environmentally friendly materials,which can be stably applied to purify the actual complicated wastewater.Here,a Ag/Ag/α-Fe_(2)O_(3) heterostructure anchored copper mesh was intentionally synthesized using a facile two-step hydrothermal method.The resultant mesh with superhydrophilicity and underwater superoleophobicity was capable of separating various oil/water mixtures with superior separation efficiency and high permeationflux driven by gravity.Benefiting from the joint effects of the smaller band gap of Ag/α-Fe_(2)O_(3) heterojunction,inherent antibacterial capacity of Ag/α-Fe_(2)O_(3) and Ag nanoparticles,favorable conductive substrate,as well as the hierarchical structure with superwettability,such mesh presented remarkably enhanced degradation capability toward organic dyes under visible light irradiation and antibacterial activity against both Escherichia coli(E.coli)and Staphylococcus aureus(S.aureus)compared with the pure Ag/α-Fe_(2)O_(3) coated mesh.Impressively,the mesh exhibited bifunctional water purification performance,in which organic dyes were eliminated simultaneously from water during oil/water separation in onefiltration process.More importantly,this mesh behaved exceptional chemical resistance,mechanical stability and long-term reusability.Therefore,this material with multifunctional integration may hold promising potential for steady water purification in practice. 展开更多
关键词 Superwetting Ag/α-Fe_(2)O_(3)heterostructure Enhanced photocatalytic and antibacterial activities Water purification long-term reusability
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Taking Comprehensive Practice Activities as the Carrier to Improve College English Teaching Efficiency
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作者 Wang Chengdong 《International English Education Research》 2015年第3期35-37,共3页
The so-called comprehensive practice activities refer to that under teachers' guidance, students conduct independent comprehensive learning activities, and in activities, students can train practice ability, organica... The so-called comprehensive practice activities refer to that under teachers' guidance, students conduct independent comprehensive learning activities, and in activities, students can train practice ability, organically combining theory knowledge and practice knowledge together, in order to have a learning and practice effect. In current college English teaching, it exists module, single and dogmatic and a series of disadvantage trends, taking comprehensive practice activities as the carrier to improve college English teaching efficiency, which has a multiplier effect. This paper first analyzes the importance of comprehensive practical activities in college English teaching activities, and then it proposes a set of practicable activity strategies, hoping to play a valuable role. 展开更多
关键词 comprehensive practice activities college English teaching IMPORTANCE suggestions
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On the Essence of Translating Activities——from the Perspective of Marxism's Practice Viewpoint
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作者 丁菲菲 《海外英语》 2014年第9X期151-153,共3页
What is the essence of translating activities?Up to now,many scholars or translators have conducted this study.This thesis aims to study the essence of translating activities from a new perspective—Marxism’s Practic... What is the essence of translating activities?Up to now,many scholars or translators have conducted this study.This thesis aims to study the essence of translating activities from a new perspective—Marxism’s Practice Viewpoint.Translating is a kind of language activity of reproduction,using another language to retell the content of the original accurately and completely.The author also makes his comments on the debate as to whether translating is a science or an art.The conclusion is that translating is neither an art nor a science.It is an activity marked by artistic creativity and scientific creativity,a scientific and artistic unity. 展开更多
关键词 Marxism’s practice VIEWPOINT TRANSLATING activitie
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Taking Comprehensive Practice Activities as the Carrier to Improve College English Teaching Efficiency
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作者 Wang Chengdong 《Journal of Zhouyi Research》 2014年第6期35-37,共3页
关键词 综合实践活动 大学英语教学 教学效率 载体 自主学习 实践能力 教学活动 学生
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Taking Comprehensive Practice Activities as the Carrier to Improve College English Teaching Efficiency
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作者 Wang Chengdong 《Journal of Zhouyi Research》 2014年第5期3-5,共3页
关键词 综合实践活动 大学英语教学 教学效率 载体 学习活动 实践能力 教学活动 行独立
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Effects of Long-Term Combined Application of Organic and Mineral Fertilizers on Microbial Biomass,Soil Enzyme Activities and Soil Fertility 被引量:52
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作者 LI Juan ZHAO Bing-qiang +2 位作者 LI Xiu-ying JIANG Rui-bo So Hwat Bing 《Agricultural Sciences in China》 CAS CSCD 2008年第3期336-343,共8页
Soil health is important for the sustainable development of terrestrial ecosystem. In this paper, we studied the relationship between soil quality and soil microbial properties such as soil microbial biomass and soil ... Soil health is important for the sustainable development of terrestrial ecosystem. In this paper, we studied the relationship between soil quality and soil microbial properties such as soil microbial biomass and soil enzyme activities in order to illustrate the function of soil microbial properties as bio-indicators of soil health. In this study, microbial biomass C and N contents (Cmic & Nmic), soil enzyme activities, and soil fertility with different fertilizer regimes were carried out based on a 15-year long-term fertilizer experiment in Drab Fluvo-aquic soil in Changping County, Beijing, China. At this site, 7 different treatments were established in 1991. They were in a wheat-maize rotation receiving either no fertilizer (CK), mineral fertilizers (NPK), mineral fertilizers with wheat straw incorporated (NPKW), mineral fertilizers with incremental wheat straw incorporated (NPKW+), mineral fertilizers plus swine manure (NPKM), mineral fertilizers plus incremental swine manure (NPKM+) or mineral fertilizers with maize straw incorporated (NPKS). In different fertilization treatments Cmic changed from 96.49 to 500.12 mg kg^-1, and Nmic changed from 35.89 to 101.82 mg kg^-1. Compared with CK, the other treatments increased Cmic & Nmic, Cmic/Corg (organic C) ratios, Cmic/Nmic, urease activity, soil organic matter (SOM), soil total nitrogen (STN), and soil total phosphorus (STP). All these properties in treatment with fertilizers input NPKM+ were the highest. Meantime, long-term combined application of mineral fertilizers with organic manure or crop straw could significantly decrease the soil pH in Fluvo-aquic soil (the pH around 8.00 in this experimental soil). Some of soil microbial properties (Cmic/Nmic, urease activity) were positively correlated with soil nutrients. Cmic/Nmic was significantly correlated with SOM and STN contents. The correlation between catalase activity and soil nutrients was not significant. In addition, except of catalase activity, the soil pH in this experiment was negatively correlated with soil microbial properties. In conclusion, soil microbial properties reflect changes of soil quality and thus can be used as bio-indicators of soil health. 展开更多
关键词 long-term fertilizer experiment soil microbial biomass soil enzyme activities soil fertility
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Changes in brain activation in stroke patients after mental practice and physical exercise: a functional MRI study 被引量:5
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作者 Hua Liu Luping Song Tong Zhang 《Neural Regeneration Research》 SCIE CAS CSCD 2014年第15期1474-1484,共11页
Mental practice is a new rehabilitation method that reters to the mental rehearsal ot motor imagery content with the goal of improving motor performance. However, the relationship between activated regions and motor r... Mental practice is a new rehabilitation method that reters to the mental rehearsal ot motor imagery content with the goal of improving motor performance. However, the relationship between activated regions and motor recovery after mental practice training is not well understood. In this study, 15 patients who suffered a firstever subcortical stroke with neurological deficits affecting the right hand, but no significant cognitive impairment were recruited. 10 patients underwent mental practice combined with physical practice training, and 5 patients only underwent physical practice training. We observed brain activation regions after 4 weeks of training, and explored the correlation of activation changes with functional recovery of the affected hands. The results showed that, after 4 weeks of mental practice combined with physical training, the Fugl-Meyer assessment score for the affected right hand was significantly increased than that after 4 weeks of practice training alone. Functional MRI showed enhanced activation in the left primary somatosensory cortex, attenuated activation intensity in the right primary motor cortex, and enhanced right cerebellar activation observed during the motor imagery task using the affected right hand after mental practice training. The changes in brain cortical activity were related to functional recovery of the hand. Experimental findings indicate that cortical and cerebellar functional reorganization following mental practice contributed to the improvement of hand function. 展开更多
关键词 nerve regeneration brain activation cortical activation somatosensory cortex corticalreorganization STROKE mental practice functional recovery motor imagery neural regeneration
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Practical Student-centered Activities of Communicative Language Teaching——Unit 2 Text A :Animals(21st Century College English Book II)
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作者 孙丽敏 冯敏敏 《海外英语》 2015年第4期113-115,共3页
English plays a very important role in our daily life and has been a world language for decades, as the global economy is developing so fast nowadays, the learners of English have already realized that the main purpos... English plays a very important role in our daily life and has been a world language for decades, as the global economy is developing so fast nowadays, the learners of English have already realized that the main purpose to learn English is to communicate properly in their real life with the people from other culture, but not to memorize those boring grammar rules and terrible vocabularies which will appear in their English examinations. Consequently, it has become an important task for English teachers to think about how to develop students' language abilities for real communication. Nowadays, Communicative Language Teaching(CLT) has become a very popular teaching approach in China. CLT pays a lot attention to the social and functional elements in language daily use. 展开更多
关键词 COMMUNICATIVE Language Teaching(CLT) COMMUNICATIVE competence practicAL activities
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Changes in Soil Microbial Activity and Community Composition as a Result of Selected Agricultural Practices 被引量:2
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作者 Martyna Glodowska Malgorzata Wozniak 《Agricultural Sciences》 2019年第3期330-351,共22页
For a constantly growing human population, healthy and productive soil is critical for sustainable delivery of agricultural products. The soil microorganisms play a crucial role in soil structure and functioning. They... For a constantly growing human population, healthy and productive soil is critical for sustainable delivery of agricultural products. The soil microorganisms play a crucial role in soil structure and functioning. They are responsible for soil formation, ecosystem biogeochemistry, cycling of nutrients and degradation of plant residues and xenobiotics. Certain agricultural treatments, such as fertilizers and pesticides applications, crop rotation, or soil amendment addition, influence the composition, abundance and function of bacteria and fungi in the soil ecosystems. Some of these practices have rather negative effects;others can help soil microorganisms by creating a friendlier habitat or providing nutrients. The changes in microbial community structure cannot be fully captured with traditional methods that are limited only to culturable organisms, which represent less than 1% of the whole population. The use of new molecular techniques such as metagenomics offers the possibility to better understand how agriculture affects soil microbiota. Therefore, the main goal of this review is to discuss how common farming practices influence microbial activity in the soil, with a special focus on pesticides, fertilizers, heavy metals and crop rotation. Furthermore, potential practices to mitigate the negative effects of some treatments are suggested and treatments that can beneficially influence soil microbiota are pointed out. Finally, application of metagenomics technique in agriculture and perspectives of developing efficient molecular tools in order to assess soil condition in the context of microbial activities are underlined. 展开更多
关键词 Agricultural practices Microbial activity Soil Microorganisms
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Influence Factors of Mobility-Related Activities of Daily Living in Chronic Dialysis Patients Needing Long-Term Care: Analysis of Long-Term Care Eligibility Assessment Survey Data
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作者 Utako Shimizu Hagiko Aoki +2 位作者 Masaru Nakamura Haruo Yamanouchi Kohei Akazawa 《Health》 2014年第16期2174-2183,共10页
Background: In the near future in Japan, chronic dialysis patients will likely face a situation where the aging and the lengthening of hemodialysis treatment periods will adversely affect the mobility-related activiti... Background: In the near future in Japan, chronic dialysis patients will likely face a situation where the aging and the lengthening of hemodialysis treatment periods will adversely affect the mobility-related activities of daily living (MR-ADL). The aim of this study was to investigate chronological change in MR-ADL among chronic dialysis patients in need of long-term care and the effect of admission to long-term care facilities on their MR-ADL. Methods: Data were analyzed from a long-term care eligibility assessment survey conducted in late March 2009 of 1000 individuals residing in Niigata City, Japan who were approved to receive long-term care. Then data from those individuals who had undergone the assessment survey ≥4 times over a period of ≥4 years were statistically evaluated. To reveal change in MR-ADL, this study performed a three-way analysis of variance with mean survey scores from assessment categories 2 - 5 containing questions related to MR-ADL as the independent variable and the number of eligibility assessment surveys (within-subjects factor), facility admission, and dialysis therapy (between-subjects factors) as dependent variables. Results: We observed the effect of facility admission in individuals aged >70 years for categories 2 - 5, and observed the effect of the number of assessment surveys taken only in women ≥80 years for categories 2 and 5. Regarding the effect of dialysis therapy, female dialysis patients aged ≥80 years and in need of long-term care scored significantly higher on survey items for transferring, grooming, toileting, eating, and instrumental activities of daily living, all of which are indicators of a moderate decline in ADL. Conclusions: Because dialysis is often initiated in women aged around 80 years, ADL in this group of individuals can be improved by the initiation and proper provision of dialysis. 展开更多
关键词 Chronic DIALYSIS PATIENTS activities of Daily Living long-term CARE INSURANCE long-term CARE INSURANCE Facility
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Evidence-Based Practice and Job Satisfaction of Nurses in Long-Term Care
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作者 Hyunwook Kang 《Open Journal of Nursing》 2016年第12期977-986,共10页
Purpose: The purpose of this study was to identify the relationship between evidence-based practice (EBP) and job satisfaction among nurses working in long-term care facilities. Methods: The study used a descriptive c... Purpose: The purpose of this study was to identify the relationship between evidence-based practice (EBP) and job satisfaction among nurses working in long-term care facilities. Methods: The study used a descriptive cross-sectional design. A total of 146 nurses working in 6 long-term care facilities in South Korea self-reported their perception of EBP implementation, barriers to research utilization, and job satisfaction. Results: The level of job satisfaction was higher in nurses who were single, older, more experienced, and had a higher income. Lower perceived barriers to research utilization were associated with greater job satisfaction. However, there was no significant relationship between a level of EBP implementation and job satisfaction. Factors influencing job satisfaction included lower barriers to the organization and communication domains of research utilization, being unmarried and older. Conclusion: Decreasing barriers to research utilization may improve the job satisfaction of nurses working in long-term care facilities. 展开更多
关键词 Evidence-Based practice Job Satisfaction long-term Care NURSE
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Practical Activities for Developing Speaking Skills of Chinese Middle School Students
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作者 Xinhai Zhang 《Sino-US English Teaching》 2004年第4期47-53,共7页
In order to develop the speaking skills of Chinese middle school students, Chinese middle school English teachers must guide the students to speak through practical speaking activities that arouse the students' inter... In order to develop the speaking skills of Chinese middle school students, Chinese middle school English teachers must guide the students to speak through practical speaking activities that arouse the students' interest, encourage the use of real language and be used with large classes. 展开更多
关键词 middle school English speaking skills practical activities
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How to identify long-term changes in groundwater caused by human activities
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《Global Geology》 1998年第1期101-101,共1页
关键词 How to identify long-term changes in groundwater caused by human activities
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Active fraction combination from Liuwei Dihuang decoction(LW-AFC) ameliorates corticosterone-induced long-term potentiation impairment in mice in vivo 被引量:4
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作者 HUANG Yan LI Dong +3 位作者 CHENG Bin LIU Gang ZHANG Yong-xiang ZHOU Wen-xia 《中国药理学与毒理学杂志》 CAS 北大核心 2019年第6期436-437,共2页
Liuwei Dihuang decoction(LW), a classic formula in traditional Chinese medicine(TCM), has been used for nearly one thousand years for various diseases with characteristic features of kidney yin deficiency. LW consists... Liuwei Dihuang decoction(LW), a classic formula in traditional Chinese medicine(TCM), has been used for nearly one thousand years for various diseases with characteristic features of kidney yin deficiency. LW consists of 6herbs including Dihuang[prepared root of Rehmannia glutinosa(Gaertn) DC], Shanyao(rhizome of Dioscorea polystachya Turcz), Shanzhuyu(fruit of Cornus officinalis Siebold Zucc), Mudanpi(root bark of Paeonia × suffruticosa Andrews),Zexie(rhizome of Alisma plantago-aquatica L) and Fuling(scleorotia of Wolfiporia extensa(Peck) Ginns)LW-active fraction combination(LW-AFC) is extracted from LW, it is effective for the treatment of kidney yin deficiency in many animal models. There are 3 fractions in LW-AFC, a polysaccharide fraction(LWB-B), a glycoside fraction(LWD-b) and an oligosaccharide fraction(CA-30). Our previous results indicate that LW-AFC has similar pharmacological effects to LW, modulating the balance of the NIM network. LW-AFC has positive effects in many animal models of kidney deficiency or disturbance of the NIM network. LW-AFC could improve the cognitive ability in Alzheimer′s disease(AD) animal models(APP/PS1, SAMP8), where modulating immune function and balancing the NIM network may play an important role in its cognition improving effects. Our study also showed that LW-AFC had protective effects on stress-induced disturbances of the NIM network. However, the underlying mechanisms remain elusive and need further investigation. OBJECTIVE This study evaluated the effects of LW-AFC and the active fractions(polysaccharide, LWB-B;glycoside, LWD-b;oligosaccharide,CA-30) on corticosterone(Cort)-induced long-term potentiation(LTP) impairment in vivo. METHODS LTP was used to evaluate the synaptic plasticity. LW-AFC was orally administered for seven days. The active fractions were given by either chronic administration(ig, ip, 7 d) or single administration(icv, ig, ip). Cort was injected subcutaneously 1 h before the high-frequency stimulation(HFS) to induce LTP impairment. Moreover, in order to research on the possible effective pathways, an antibiotic cocktail and an immunosuppressant were also used. RESULTS Chronic administration(ig) of LW-AFC and its three active fractions could ameliorate Cort-induced LTP impairment. Single administration(icv, ig, ip) of any of the active fractions had no effect on Cort-induced LTP impairment, while chronic administration(ig, ip) of LWB-B or LWD-b showed positive effects against Cort. Interestingly, CA-30 only showed protective effects via ig administration,and there was little effect when CA-30 was administered ip In addition, when the intestinal microbiota was disrupted by application of the antibiotic cocktail, CA-30 showed little protective effects against Cort. The effects of LW-AFC were also abolished when the immune function was inhibited. In the hippocampal tissue, Cort treatment increased corticosterone and glutamate, and LW-AFC could inhibit the Cort-induced elevation of corticosterone and glutamate;there was little change in D-serine in Cort-treated animals, but LW-AFC could increase the D-serine levels. CONCLUSION LW-AFC and its three active fractions could ameliorate Cort-induced LTP impairment. Their protective effects are unlikely by a direct way, and immune modulation might be the common pathway. CA-30 could protect LTP from impairment via modulating the intestinal microbiota. Decreasing corticosterone and glutamate and increasing D-serine in the Cort-treated animals’ hippocampal tissue might be one of the mechanisms for the neural protective effects of LW-AFC. Further study is needed to understand the underlying mechanisms. 展开更多
关键词 LW-active fraction COMBINATION activE FRACTIONS CORTICOSTERONE long-term POTENTIATION SYNAPTIC plasticity stress
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Effects of Long-term Fertilization on Soil M icrobial Com m unity Structure,Labile Organic Carbon and Nitrogen and Enzym e Activity in Paddy Field and Upland 被引量:4
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作者 Wang Guiyue Su Ting +3 位作者 Han Hailiang Tan Heping Bao Fei Zhao Fucheng 《Meteorological and Environmental Research》 CAS 2019年第5期105-111,共7页
To investigate the effects of long-term fertilization systems on soil microbial community structure,labile organic carbon and nitrogen and enzyme activity in yellow sand paddy field and upland,a field experiment was c... To investigate the effects of long-term fertilization systems on soil microbial community structure,labile organic carbon and nitrogen and enzyme activity in yellow sand paddy field and upland,a field experiment was conducted at the experimental station of Dongyang Institute of Maize Research in Zhejiang Province,China in 2009.The experiment consisted of six treatments with three replicates,and they were arranged in a completely randomized design,including no fertilization in paddy field (PCK),conventional fertilization in paddy field (PCF),formulated fertilization by soil testing in paddy field (PSTF),formulated fertilization by soil testing with organic manure in paddy field (PSTF+OF),conventional fertilization on upland (DCF),and formulated fertilization by soil testing with organic manure on upland (DSTF+OF).Soil nutrients,enzyme activity,microbial biomass and community structure were determined in 2015.The results showed that compared with no fertilization in paddy field (PCK),fertilization increased soil phosphorus and potassium content,and decreased pH value.No fertilization in paddy field (PCK) had no significant effect on soil culturable microorganisms in paddy field and upland,but formulated fertilization by soil testing with organic manure on upland (DSTF+OF) significantly increased the number of fungi.Formula fertilization by soil testing with organic manure (PSTF+OF) also significantly increased soil microbial biomass carbon and nitrogen in paddy field and upland.Moreover,fertilization had no significant effect on soil cellulase activity,but formula fertilization by soil testing with organic manure (PSTF+OF) significantly increased soil dehydrogenase and catalase activity.Therefore,long-term application of chemical fertilizer with organic fertilizer can effectively improve soil fertility. 展开更多
关键词 long-term fertilization Paddy field UPLAND Microbial community STRUCTURE SOIL enzyme activITY
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Long-term adenosine A1 receptor activation-induced sortilin expression promotes α-synuclein upregulation in dopaminergic neurons 被引量:5
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作者 Yun-Cheng Lv An-Bo Gao +7 位作者 Jing Yang Li-Yuan Zhong Bo Jia Shu-Hui Ouyang Le Gui Tian-Hong Peng Sha Sun Francisco S.Cayabyab 《Neural Regeneration Research》 SCIE CAS CSCD 2020年第4期712-723,共12页
Prolonged activation of adenosine A1 receptor likely leads to damage of dopaminergic neurons and subsequent development of neurodegenerative diseases.However,the pathogenesis underlying long-term adenosine A1 receptor... Prolonged activation of adenosine A1 receptor likely leads to damage of dopaminergic neurons and subsequent development of neurodegenerative diseases.However,the pathogenesis underlying long-term adenosine A1 receptor activation-induced neurodegeneration remains unclear.In this study,rats were intraperitoneally injected with 5 mg/kg of the adenosine A1 receptor agonist N6-cyclopentyladenosine(CPA)for five weeks.The mobility of rats was evaluated by forced swimming test,while their cognitive capabilities were evaluated by Y-maze test.Expression of sortilin,α-synuclein,p-JUN,and c-JUN proteins in the substantia nigra were detected by western blot analysis.In addition,immunofluorescence staining of sortilin andα-synuclein was performed to detect expression in the substantia nigra.The results showed that,compared with adenosine A1 receptor antagonist 8-cyclopentyl-1,3-dipropylxanthine(5 mg/kg)+CPA co-treated rats,motor and memory abilities were reduced,surface expression of sortin andα-synuclein in dopaminergic neurons was reduced,and total sortilin and totalα-synuclein were increased in CPA-treated rats.MN9D cells were incubated with 500 nM CPA alone or in combination with 10μM SP600125(JNK inhibitor)for 48 hours.Quantitative real-time polymerase chain reaction analysis of sortilin andα-synuclein mRNA levels in MN9D cells revealed upregulated sortilin expression in MN9D cells cultured with CPA alone,but the combination of CPA and SP600125 could inhibit this expression.Predictions made using Jasper,PROMO,and Alibaba online databases identified a highly conserved sequence in the sortilin promoter that was predicted to bind JUN in both humans and rodents.A luciferase reporter assay of sortilin promoter plasmid-transfected HEK293T cells confirmed this prediction.After sortilin expression was inhibited by sh-SORT1,expression of p-JUN and c-JUN was detected by western blot analysis.Long-term adenosine A1 receptor activation levels upregulatedα-synuclein expression at the post-transcriptional level by affecting sortilin expression.The online tool Raptor-X-Binding and Discovery Studio 4.5 prediction software predicted that sortilin can bind toα-synuclein.Co-immunoprecipitation revealed an interaction between sortilin andα-synuclein in MN9D cells.Our findings indicate that suppression of prolonged adenosine A1 receptor activation potently inhibited sortilin expression andα-synuclein accumulation,and dramatically improved host cognition and kineticism.This study was approved by the University Committee of Animal Care and Supply at the University of Saskatchewan(approval No.AUP#20070090)in March 2007 and the Animals Ethics Committee of University of South China(approval No.LL0387-USC)in June 2017. 展开更多
关键词 cognitive dysfunction DOPAMINERGIC neuron DYSKINESIA JNK/c-JUN pathway long-term adenosine A1 receptor activation neural regeneration NEURODEGENERATIVE diseases SORTILIN Α-SYNUCLEIN
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Long-Term Trends in Photosynthetically Active Radiation in Beijing 被引量:1
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作者 胡波 王跃思 刘广仁 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2010年第6期1380-1388,共9页
A long-term dataset of photosynthetically active radiation (Qp) is reconstructed from a broadband global solar radiation (Rs) dataset through an all-weather reconstruction model. This method is based on four years... A long-term dataset of photosynthetically active radiation (Qp) is reconstructed from a broadband global solar radiation (Rs) dataset through an all-weather reconstruction model. This method is based on four years' worth of data collected in Beijing. Observation data of Rs and Qp from 2005-2008 are used to investigate the temporal variability of Qp and its dependence on the clearness index and solar zenith angle. A simple and effcient all-weather empirically derived reconstruction model is proposed to reconstruct Qp from Rs. This reconstruction method is found to estimate instantaneous Qp with high accuracy. The annual mean of the daily values of Qp during the period 1958-2005 period is 25.06 mol m-2 d-1. The magnitude of the long-term trend for the annual averaged Qp is presented (-0.19 mol m-2 yr-1 from 1958-1997 and -0.12 mol m-2 yr-1 from 1958-2005). The trend in Qp exhibits sharp decreases in the spring and summer and more gentle decreases in the autumn and winter. 展开更多
关键词 photosynthetically active radiation historical data reconstruction long-term trends
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Safety and Quality of Care Evaluation in Japanese Long-Term Facilities Focused on the Activity Condition and Cognitive Function of Residents 被引量:1
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作者 Sayuri Kaneko 《Open Journal of Nursing》 2020年第2期131-142,共12页
Objective: Currently, standards for evaluating long-term care facilities do not exist in Japan. This study aimed to evaluate the quality of healthcare services in Japan’s long-term care facilities and identify the st... Objective: Currently, standards for evaluating long-term care facilities do not exist in Japan. This study aimed to evaluate the quality of healthcare services in Japan’s long-term care facilities and identify the structural and process indicators associated with the facilities’ outcome indicators. Methods: This retrospective study assessed changes in residents’ abilities to participate in physical activities, their cognitive function, and their vulnerability to injuries. From 2012 to 2013, we collected information on the healthcare services at 1067 long-term care facilities registered with Japan’s Welfare, Health and Medical Care Information Network in the Welfare and Medical Service Agency. We examined 12 structural indicators, 26 process indicators, and 7 outcome indicators. We used multivariate linear regression models adjusted to analyze relationships between outcome indicators and structural or process indicators. Results: Residents’ activity and cognitive function indicators either improved by 80% - 90% or were maintained for one year. The Geriatric Functional Independence Measures, the Barthel Index, and holding conferences related to care were all considered activities of daily living. Three adverse events—tumbles and falls, behavioral problems, and aimless wandering or leaving the facility without permission—were factors that restricted residents’ behavior and number of residents per care staff member. Conclusions: Maintaining or improving levels of independence and cognition in daily living requires a care process system that enables ongoing monitoring of residents’ activities of daily living and cognitive functioning. Ensuring the safety of residents and improving the quality of care in long-term care facilities without securing adequate care staff are not possible. 展开更多
关键词 activity CONDITION Cognitive Function long-term CARE Facility SAFETY Quality of CARE
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LW-AFC and its active components ameliorate corticosterone-induced long-term potentiation impairment in mice
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作者 Yan HUANG Dong LI +1 位作者 Wen-xia ZHOU Yong-xiang ZHANG 《中国药理学与毒理学杂志》 CAS CSCD 北大核心 2017年第10期989-990,共2页
OBJECTIVE LW-AFC is extracted from the classical traditional Chinese medicinal prescription-Liuwei Dihuang Decoction.Previous studies have showed that LW-AFC could improve learning&memory ability in amny animal mo... OBJECTIVE LW-AFC is extracted from the classical traditional Chinese medicinal prescription-Liuwei Dihuang Decoction.Previous studies have showed that LW-AFC could improve learning&memory ability in amny animal models.In this study,we focused on evaluating the effect of several main active components fromLW-AFC(B-B;loganin,LOG;morroniside,MOR;paeoniflorin,PF and stachyose,STA)on LTP.METHODS In vivo recording of LTP was used in this study to evaluate the effects of LW-AFC and it′s active components on coticorsterone(Cort)induced LTP impairment.RESULTS The results showed that LW-AFC could ameliorate Cort-induced LTP impairment.The effect of LW-AFC was abolished when the immune function was inhibited.Single administration(ig,ip,icv)of any of the components had no effect on Cort-induced LTP impairment.Consecutively intragastric administration or intraperitoneal injections(chronic administration)of B-B,LOG,MOR or PF for 7 d showed protective effect on Cort-induced LTP impairment.Intragastric administration of STA for 7 d protected LTP from impairment induced by Cort,while there was little improving effect when STA was administrated via intraperitoneal injection.In addition,when the intestinal microbiota was disrupted by applying the antibiotic cocktail,STA showed little protective effect against Cort.CONCLUSION In conclusion,LW-AFC and it′s components showed positive effects against cort induced LTP impairment,it seems that all displayed protective effects via indirectly,immune modulation might be the common pathway for all components;the exact pathways are different in each component,B-B,LOG,MOR and PF could be absorbed into the bloods tream and then modulate the peripheral immune function,while STA could not be absorbed and modulates the immune function via modulating intestinal microbiota.Further studies are needed to invesgate the underlying mechanisms and the synergetic effects of all components. 展开更多
关键词 LW-AFC active components synaptic plasticity long-term potentiation intestinal microbiota
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Mechanisms of active fraction combination from Liuwei Dihuang Decoction(LW-AFC) on long-term potentiation impairment in vivo
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作者 HUANG Yan LI Dong +3 位作者 CHENG Bin LIU Gang ZHANG Yong-xiang ZHOU Wen-xia 《中国药理学与毒理学杂志》 CAS 北大核心 2019年第9期665-665,共1页
OBJECTIVE Liuwei Dihuang Decoction(LW)-active fraction combination(LW-AFC,consist of 3 fractions polysaccharide,LWB-B;glycoside,LWD-b;oligosaccharide,CA-30)is extracted from LW,it is effective for the treatment of kid... OBJECTIVE Liuwei Dihuang Decoction(LW)-active fraction combination(LW-AFC,consist of 3 fractions polysaccharide,LWB-B;glycoside,LWD-b;oligosaccharide,CA-30)is extracted from LW,it is effective for the treatment of kidney yin deficiency in many animal models.This study evaluated the effects and mechanisms of LW-AFC and the active fractions on corticosterone(Cort)-induced long-term potentiation(LTP)impairment in vivo.METHODS LTP was used to evaluate the synaptic plasticity.LW-AFC was orally administered for seven days.The active fractions were given by either chronic administration(ig,ip,7 d)or single administration(icv,ig,ip).Cort was injected subcutaneously 1h before the high-frequency stimulation(HFS)to induce LTP impairment.Moreover,in order to research on the possible effective pathways,an antibiotic cocktail and an immunosuppressant were also used.RESULTS Chronic administration(ig)of LW-AFC and its three active fractions could ameliorate Cort-induced LTP impairment.Single administration(icv,ig,ip)of any of the active fractions had no effect on Cort-induced LTP impairment,while chronic administration(ig,ip)of LWB-B or LWD-b showed positive effects against Cort.Interestingly,CA-30 only showed protective effects via ig administration,and there was little effect when CA-30 was administered ip In addition,when the intestinal microbiota was disrupted by application of the antibiotic cocktail,CA-30 showed little protective effects against Cort.The effects of LW-AFC were also abolished when the immune function was inhibited.In the hippocampal tissue,Cort treatment increased Cort and glutamate,and LW-AFC could inhibit the Cort-induced elevation of Cort and glutamate;there was little change in D-serine in Cort-treated animals,but LW-AFC could increase the D-serine levels.CONCLUSION LW-AFC and its three active fractions could ameliorate Cort-induced LTP impairment.Their protective effects are unlikely by a direct way,and immune modulation might be the common pathway.CA-30 could protect LTP from impairment via modulating the intestinal microbiota.Decreasing Cort and glutamate and increasing D-serine in the Cort-treated animals'hippocampal tissue might be one of the mechanisms for the neural protective effects of LW-AFC.Further study is needed to understand the underlying mechanisms. 展开更多
关键词 LW-active fraction combination active fractions CORTICOSTERONE long-term potentiation synaptic plasticity stress
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