BACKGROUND Obstructive sleep apnea-hypopnea syndrome(OSAHS)is primarily caused by airway obstruction due to narrowing and blockage in the nasal and nasopha-ryngeal,oropharyngeal,soft palate,and tongue base areas.The m...BACKGROUND Obstructive sleep apnea-hypopnea syndrome(OSAHS)is primarily caused by airway obstruction due to narrowing and blockage in the nasal and nasopha-ryngeal,oropharyngeal,soft palate,and tongue base areas.The mid-frequency anti-snoring device is a new technology based on sublingual nerve stimulation.Its principle is to improve the degree of oropharyngeal airway stenosis in OSAHS patients under mid-frequency wave stimulation.Nevertheless,there is a lack of clinical application and imaging evidence.METHODS We selected 50 patients diagnosed with moderate OSAHS in our hospital between July 2022 and August 2023.They underwent a 4-wk treatment regimen involving the mid-frequency anti-snoring device during nighttime sleep.Following the treatment,we monitored and assessed the sleep apnea quality of life index and Epworth Sleepiness Scale scores.Additionally,we performed computed tomo-graphy scans of the oropharynx in the awake state,during snoring,and while using the mid-frequency anti-snoring device.Cross-sectional area measurements in different states were taken at the narrowest airway point in the soft palate posterior and retrolingual areas.RESULTS Compared to pretreatment measurements,patients exhibited a significant reduction in the apnea-hypopnea index,the percentage of time with oxygen saturation below 90%,snoring frequency,and the duration of the most prolonged apnea event.The lowest oxygen saturation showed a notable increase,and both sleep apnea quality of life index and Epworth Sleepiness Scale scores improved.Oropharyngeal computed tomography scans revealed that in OSAHS patients cross-sectional areas of the oropharyngeal airway in the soft palate posterior area and retrolingual area decreased during snoring compared to the awake state.Conversely,during mid-frequency anti-snoring device treatment,these areas increased compared to snoring.CONCLUSION The mid-frequency anti-snoring device demonstrates the potential to enhance various sleep parameters in patients with moderate OSAHS,thereby improving their quality of life and reducing daytime sleepiness.These therapeutic effects are attributed to the device’s ability to ameliorate the narrowing of the oropharynx in OSAHS patients.展开更多
The wave-based method （WBM） has been applied for the prediction of mid-frequency vibrations of fiat plates. The scaling factors, Gauss point selection rule and truncation rule are introduced to insure the wave model...The wave-based method （WBM） has been applied for the prediction of mid-frequency vibrations of fiat plates. The scaling factors, Gauss point selection rule and truncation rule are introduced to insure the wave model to converge. Numerical results show that the prediction tech- nique based on WBM is with higher accuracy and smaller computational effort than the one on FEM, which implies that this new technique on WBM can be applied to higher-frequency range.展开更多
The present paper reviews the vibro-acoustic modelling of extruded aluminium train floor structures including the state-of-the-art of its industrial applications, as well as the most recent developments on mid-frequen...The present paper reviews the vibro-acoustic modelling of extruded aluminium train floor structures including the state-of-the-art of its industrial applications, as well as the most recent developments on mid-frequency mod- elling techniques in general. With the common purpose to predict mid-frequency vibro-acoustic responses of stiffened panel structures to an acceptable accuracy at a reasonable computational cost, relevant techniques are mainly based on one of the following three types of mid-frequency vibro- acoustic modelling principles： （1） enhanced deterministic methods, （2） enhanced statistical methods, and （3） hybrid deterministic/statistical methods. It is shown that, although recent developments have led to a significant step forward in industrial applicability, mature and adequate prediction tech- niques, however, are still very much required for solving sound transmission through, and radiation from, extruded aluminium panels used on high-speed trains. Due to their great potentials for predicting mid-frequency vibro-acoustics of stiffened panel structures, two of recently developed mid-frequency modelling approaches, i.e. the so-called hybrid finite element-statistical energy analysis （FE-SEA） and hybrid wave-based method- statistical energy analysis （WBM-SEA）, are then recapitulated.展开更多
Mid-frequency wavefront errors can be of the most importance for some optical components, but they're not explicitly covered by corresponding international standards such as ISO 10110. The testing methods for the ...Mid-frequency wavefront errors can be of the most importance for some optical components, but they're not explicitly covered by corresponding international standards such as ISO 10110. The testing methods for the errors also have a lot of aspects to be improved. This paper gives an overview of the specifications especially of PSD. NIF, developed by America, and XMM, developed by Europe, have both discovered some new testing methods.展开更多
Objective:To study the effect of mid-frequency pulse therapy combined with external fixation on bone metabolism, inflammatory response and oxidative stress in patients with osteoporotic distal radial fractures.Methods...Objective:To study the effect of mid-frequency pulse therapy combined with external fixation on bone metabolism, inflammatory response and oxidative stress in patients with osteoporotic distal radial fractures.Methods: A total of 72 patients with osteoporotic distal radial fractures who were treated in the hospital between September 2015 and January 2017 were collected and divided into control group (n=36) and observation group (n=36) according to the random number table method. Control group received routine external fixation, and observation group received mid-frequency pulse therapy combined with external fixation. The differences in serum levels of bone metabolism indexes, inflammatory factors and oxidative stress indexes were compared between two groups of patients before and after treatment.Results: Before treatment, differences in serum levels of bone metabolism indexes, inflammatory factors and oxidative stress indexes were not statistically significant between the two groups. After 1 month of treatment, serum BGP, TAC and SOD levels of both groups of patients were higher than those before treatment whileβ-CTX, AKP, TRAP, CRP, IL-1β, IL-6 and MDA levels were lower than those before treatment, and serum BGP, TAC and SOD levels of observation group were higher than those of control group whileβ-CTX, AKP, TRAP, CRP, IL-1β, IL-6 and MDA levels were lower than those of control group.Conclusion: Mid-frequency pulse therapy combined with external fixation can promote fracture healing and reduce postoperative inflammatory response and oxidative stress response in patients with osteoporotic distal radial fracture.展开更多
文摘BACKGROUND Obstructive sleep apnea-hypopnea syndrome(OSAHS)is primarily caused by airway obstruction due to narrowing and blockage in the nasal and nasopha-ryngeal,oropharyngeal,soft palate,and tongue base areas.The mid-frequency anti-snoring device is a new technology based on sublingual nerve stimulation.Its principle is to improve the degree of oropharyngeal airway stenosis in OSAHS patients under mid-frequency wave stimulation.Nevertheless,there is a lack of clinical application and imaging evidence.METHODS We selected 50 patients diagnosed with moderate OSAHS in our hospital between July 2022 and August 2023.They underwent a 4-wk treatment regimen involving the mid-frequency anti-snoring device during nighttime sleep.Following the treatment,we monitored and assessed the sleep apnea quality of life index and Epworth Sleepiness Scale scores.Additionally,we performed computed tomo-graphy scans of the oropharynx in the awake state,during snoring,and while using the mid-frequency anti-snoring device.Cross-sectional area measurements in different states were taken at the narrowest airway point in the soft palate posterior and retrolingual areas.RESULTS Compared to pretreatment measurements,patients exhibited a significant reduction in the apnea-hypopnea index,the percentage of time with oxygen saturation below 90%,snoring frequency,and the duration of the most prolonged apnea event.The lowest oxygen saturation showed a notable increase,and both sleep apnea quality of life index and Epworth Sleepiness Scale scores improved.Oropharyngeal computed tomography scans revealed that in OSAHS patients cross-sectional areas of the oropharyngeal airway in the soft palate posterior area and retrolingual area decreased during snoring compared to the awake state.Conversely,during mid-frequency anti-snoring device treatment,these areas increased compared to snoring.CONCLUSION The mid-frequency anti-snoring device demonstrates the potential to enhance various sleep parameters in patients with moderate OSAHS,thereby improving their quality of life and reducing daytime sleepiness.These therapeutic effects are attributed to the device’s ability to ameliorate the narrowing of the oropharynx in OSAHS patients.
基金Project supported by the National Natural Science Foundation of China (No.10472035).
文摘The wave-based method （WBM） has been applied for the prediction of mid-frequency vibrations of fiat plates. The scaling factors, Gauss point selection rule and truncation rule are introduced to insure the wave model to converge. Numerical results show that the prediction tech- nique based on WBM is with higher accuracy and smaller computational effort than the one on FEM, which implies that this new technique on WBM can be applied to higher-frequency range.
基金sponsored by the NationalNatural foundation of China(Grant Nos.U1434201 and 51175300)
文摘The present paper reviews the vibro-acoustic modelling of extruded aluminium train floor structures including the state-of-the-art of its industrial applications, as well as the most recent developments on mid-frequency mod- elling techniques in general. With the common purpose to predict mid-frequency vibro-acoustic responses of stiffened panel structures to an acceptable accuracy at a reasonable computational cost, relevant techniques are mainly based on one of the following three types of mid-frequency vibro- acoustic modelling principles： （1） enhanced deterministic methods, （2） enhanced statistical methods, and （3） hybrid deterministic/statistical methods. It is shown that, although recent developments have led to a significant step forward in industrial applicability, mature and adequate prediction tech- niques, however, are still very much required for solving sound transmission through, and radiation from, extruded aluminium panels used on high-speed trains. Due to their great potentials for predicting mid-frequency vibro-acoustics of stiffened panel structures, two of recently developed mid-frequency modelling approaches, i.e. the so-called hybrid finite element-statistical energy analysis （FE-SEA） and hybrid wave-based method- statistical energy analysis （WBM-SEA）, are then recapitulated.
文摘Mid-frequency wavefront errors can be of the most importance for some optical components, but they're not explicitly covered by corresponding international standards such as ISO 10110. The testing methods for the errors also have a lot of aspects to be improved. This paper gives an overview of the specifications especially of PSD. NIF, developed by America, and XMM, developed by Europe, have both discovered some new testing methods.
文摘Objective:To study the effect of mid-frequency pulse therapy combined with external fixation on bone metabolism, inflammatory response and oxidative stress in patients with osteoporotic distal radial fractures.Methods: A total of 72 patients with osteoporotic distal radial fractures who were treated in the hospital between September 2015 and January 2017 were collected and divided into control group (n=36) and observation group (n=36) according to the random number table method. Control group received routine external fixation, and observation group received mid-frequency pulse therapy combined with external fixation. The differences in serum levels of bone metabolism indexes, inflammatory factors and oxidative stress indexes were compared between two groups of patients before and after treatment.Results: Before treatment, differences in serum levels of bone metabolism indexes, inflammatory factors and oxidative stress indexes were not statistically significant between the two groups. After 1 month of treatment, serum BGP, TAC and SOD levels of both groups of patients were higher than those before treatment whileβ-CTX, AKP, TRAP, CRP, IL-1β, IL-6 and MDA levels were lower than those before treatment, and serum BGP, TAC and SOD levels of observation group were higher than those of control group whileβ-CTX, AKP, TRAP, CRP, IL-1β, IL-6 and MDA levels were lower than those of control group.Conclusion: Mid-frequency pulse therapy combined with external fixation can promote fracture healing and reduce postoperative inflammatory response and oxidative stress response in patients with osteoporotic distal radial fracture.
