期刊文献+
共找到384篇文章
< 1 2 20 >
每页显示 20 50 100
Observation of Low-Level Jets in the Eastern Tropical Indian Ocean Based on Shipborne Coherent Doppler Lidar
1
作者 WANG Haiyuan LIU Lin +10 位作者 FAN Mengqi YANG Yang YANG Guang DUAN Yongliang LIU Baochao SU Qinglei ZHANG Binbin WANG Fengjun SHI Xuliang LI Qiuchi ZENG Ai 《Journal of Ocean University of China》 SCIE CAS CSCD 2024年第5期1163-1172,共10页
In contrast to the Pacific and Atlantic Oceans,the Indian Ocean has lacked in-situ observations of wind profiles over open sea areas for decades.In 2021,a shipborne coherent Doppler lidar(CDL)was used to observe in-si... In contrast to the Pacific and Atlantic Oceans,the Indian Ocean has lacked in-situ observations of wind profiles over open sea areas for decades.In 2021,a shipborne coherent Doppler lidar(CDL)was used to observe in-situ wind profiles in the eastern tropical Indian Ocean.This equipment successfully captured low-level jets(LLJs)in the region,and their characteristics were thoroughly analyzed.Results reveal that the observed wind speed of LLJs in the eastern Indian Ocean ranges from 6 m s^(-1) to 10 m s^(-1) during the boreal winter and spring seasons,showing a height range of 0.6 to 1 km and two peak times at 0800 and 2000 UTC.This wind shear is weaker than that in land or offshore areas,ranging from 0 s^(-1) to 0.006 s^(-1).Moreover,the accuracy of the CDL data is compared to that of ERA5 data in the study area.The results indicate that the zonal wind from ERA5 data significantly deviated from the CDL measurement data,and the overall ERA5 data are substantially weaker than the in-situ observations.Notably,ERA5 underestimates northwestward LLJs. 展开更多
关键词 low-level jets coherent Doppler lidar ERA5 RADIOSONDE eastern Indian Ocean
下载PDF
The Roles of Low-level Jets in “21·7” Henan Extremely Persistent Heavy Rainfall Event 被引量:14
2
作者 Yuhan LUO Yu DU 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2023年第3期350-373,共24页
An extremely heavy rainfall event lasting from 17 to 22 July 2021 occurred in Henan Province of China, with accumulated precipitation of more than 1000 mm over a 6-day period that exceeded its mean annual precipitatio... An extremely heavy rainfall event lasting from 17 to 22 July 2021 occurred in Henan Province of China, with accumulated precipitation of more than 1000 mm over a 6-day period that exceeded its mean annual precipitation. The present study examines the roles of persistent low-level jets(LLJs) in maintaining the precipitation using surface station observations and reanalysis datasets. The LLJs triggered strong ascending motions and carried moisture mainly from the outflow of Typhoon In-fa(2021). The varying directions of the LLJs well corresponded to the meridional shifts of the rainfall. The precipitation rate reached a maximum during 20-21 July as the LLJs strengthened and expanded vertically into double LLJs, including synoptic-weather-system-related LLJs(SLLJs) at 850–700 hPa and boundary-layer jets(BLJs)at ~950 hPa. The coupling of the SLLJ and BLJ provided strong mid-and low-level convergence on 20 July, whereas the SLLJ produced mid-level divergence at its entrance that coupled with low-level convergence at the terminus of the BLJ on21 July. The formation mechanisms of the two types of LLJs are further examined. The SLLJs and the low-pressure vortex(or inverted trough) varied synchronously as a whole and were affected by the southwestward movement of the WPSH in the rainiest period. The persistent large total pressure gradient force at low levels also maintained the strength of low-level geostrophic winds, thus sustaining the BLJs on the synoptic scale. The results based on a Du-Rotunno 1D model show that the Blackadar and Holton mechanisms jointly governed the BLJ dynamics on the diurnal scale. 展开更多
关键词 extremely persistent heavy rainfall low-level jet dynamic and thermodynamic effect diurnal cycle
下载PDF
A novel method for gamma spectrum analysis of low-level and intermediate-level radioactive waste 被引量:2
3
作者 Hui Yang Xin-Yu Zhang +4 位作者 Wei-Guo Gu Bing Dong Xue-Zhi Jiang Wen-Tao Zhou De-Zhong Wang 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2023年第6期199-213,共15页
The uncertainty of nuclide libraries in the analysis of the gamma spectra of low-and intermediate-level radioactive waste(LILW)using existing methods produces unstable results.To address this problem,a novel spectral ... The uncertainty of nuclide libraries in the analysis of the gamma spectra of low-and intermediate-level radioactive waste(LILW)using existing methods produces unstable results.To address this problem,a novel spectral analysis method is proposed in this study.In this method,overlapping peaks are located using a continuous wavelet transform.An improved quadratic convolution method is proposed to calculate the widths of the peaks and establish a fourth-order filter model to estimate the Compton edge baseline with the overlapping peaks.Combined with the adaptive sensitive nonlinear iterative peak,this method can effectively subtracts the background.Finally,a function describing the peak shape as a filter is used to deconvolve the energy spectrum to achieve accurate qualitative and quantitative analyses of the nuclide without the aid of a nuclide library.Gamma spectrum acquisition experiments for standard point sources of Cs-137 and Eu-152,a segmented gamma scanning experiment for a 200 L standard drum,and a Monte Carlo simulation experiment for triple overlapping peaks using the closest energy of three typical LILW nuclides(Sb-125,Sb-124,and Cs-134)are conducted.The results of the experiments indicate that(1)the novel method and gamma vision(GV)with an accurate nuclide library have the same spectral analysis capability,and the peak area calculation error is less than 4%;(2)compared with the GV,the analysis results of the novel method are more stable;(3)the novel method can be applied to the activity measurement of LILW,and the error of the activity reconstruction at the equivalent radius is 2.4%;and(4)The proposed novel method can quantitatively analyze all nuclides in LILW without a nuclide library.This novel method can improve the accuracy and precision of LILW measurements,provide key technical support for the reasonable disposal of LILW,and ensure the safety of humans and the environment. 展开更多
关键词 HPGe detector low-level and intermediate-level radioactive waste Gamma spectrum analysis method Deconvolution method Continuous wavelet transform
下载PDF
Axial length shortening in myopic children with Stickler syndrome after repeated low-level red-light therapy 被引量:1
4
作者 Xiang-Hua Tang Meng-Ting Yu +2 位作者 Yin Hu Ming-Guang He Xiao Yang 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2023年第10期1712-1717,共6页
AIM:To report the myopia-controlling effect of repeated low-level red-light(RLRL)therapy in patients with Stickler syndrome(STL),an inherited collagenic disease typically presenting with early onset myopia.METHODS:Thr... AIM:To report the myopia-controlling effect of repeated low-level red-light(RLRL)therapy in patients with Stickler syndrome(STL),an inherited collagenic disease typically presenting with early onset myopia.METHODS:Three STL children,aged 3,7,and 11y,received RLRL therapy throughout the follow-up period of 17,3,and 6mo,respectively after exclusion of fundus anomalies.Data on best-corrected visual acuity(BCVA),intraocular pressure,cycloplegic subjective refraction,ocular biometrics,scanning laser ophthalmoscope,optical coherence tomography,genetic testing,systemic disease history,and family history were recorded.RESULTS:At the initiation of the RLRL therapy,the spherical equivalent(SE)of 6 eyes from 3 patients ranged from-3.75 to-20.38 D,axial length(AL)were from 23.88 to 30.68 mm,and BCVA were from 0.4 to 1.0(decimal notation).Myopia progression of all six eyes slowed down after RLRL therapy.AL in five out of the six eyes shortened-0.07 to-0.63 mm.No side effects were observed.CONCLUSION:Three cases of STL whose progression of myopic shift and AL elongation are successfully reduced and even reversed after RLRL therapy. 展开更多
关键词 Stickler syndrome axial length shortening MYOPIA repeated low-level red-light therapy
下载PDF
Formation of Low-Level Jets over Southern China in the Mei-yu Season
5
作者 Xuanyu LIU Guixing CHEN +1 位作者 Sijia ZHANG Yu DU 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2023年第10期1731-1748,共18页
This study examines the diversity of low-level jet(LLJ)formation and related physical processes over southern China.A total of 171 LLJ formation events with enhanced daily southwesterlies and early-morning maximum win... This study examines the diversity of low-level jet(LLJ)formation and related physical processes over southern China.A total of 171 LLJ formation events with enhanced daily southwesterlies and early-morning maximum wind speeds were observed during the mei-yu seasons of 1989–2018.The LLJs can be further categorized into four types based on the increases in the daily mean and diurnal amplitude of the low-level winds.Analysis of the synoptic-scale disturbances shows that the two types of LLJ formation(Q1 and Q4),which feature large increases of daily southerly wind components,are mainly induced by west-east dipole patterns of pressure change,in association with the enhanced southwest vortex and/or the western Pacific subtropical high(WPSH).In contrast,the other two types(Q2 and Q3),which feature relatively large increases in their daily westerly components,are related to a northwest-southeast dipole pattern of pressure change due to the mid-latitude trough and the WPSH.We further analyze the considerable variations in the diurnal thermal forcing among the LLJ formation events.The strong(weak)daytime heating of solar radiation leads to relatively large(small)increases in the diurnal amplitude of low-level winds in Q1 and Q2(Q3 and Q4)types.Therefore,different combinations of synopticscale disturbances and diurnal thermal forcings are found to account for the diversity in LLJ formation and associated differences in downstream rainfall patterns.These results help to improve our understanding and prediction of the formation of LLJs. 展开更多
关键词 low-level jets formation processes diurnal variations synoptic-scale disturbances
下载PDF
A Visit by Personages of the Liberal International
6
作者 Li Qingzhen 《International Understanding》 1997年第2期12-13,共2页
AVisitbyPersonagesoftheLiberalInternationalbyLiQingzhenAttheinvitationoftheChineseAssociationforInternationa... AVisitbyPersonagesoftheLiberalInternationalbyLiQingzhenAttheinvitationoftheChineseAssociationforInternationalUnderstanding(CA... 展开更多
关键词 A Visit by personages of the Liberal International
下载PDF
Thermodynamics and Microphysical Characteristics of an Extreme Rainfall Event Under the Influence of a Low-level Jet over the South China Coast
7
作者 徐碧裕 黎慧琦 +7 位作者 叶朗明 刘显通 饶晓娜 肖辉 徐加民 林青 蒲义良 黄青兰 《Journal of Tropical Meteorology》 SCIE 2023年第2期216-235,共20页
In this paper,the data of Automatic Weather Stations(AWSs),ERA5 reanalysis,sounding,wind profile radar,and dual-polarization radar are used to study an extreme rainfall event in the south China Coast on 11 to 12 May 2... In this paper,the data of Automatic Weather Stations(AWSs),ERA5 reanalysis,sounding,wind profile radar,and dual-polarization radar are used to study an extreme rainfall event in the south China Coast on 11 to 12 May 2022 from the aspects of thermodynamics and microphysical characteristics under the influence of low-level jets(LLJs).Results show that:(1)The extreme rainfall event can be divided into two stages:the first stage(S1)from 0000 to 0600 LST on May 12 and the second stage(S2)from 0700 to 1700 LST on the same day.During S1,the rainfall is mainly caused by the upper-level shortwave trough and the boundary layer jet(BLJ),characterized by strong upward motion on the windward side of mountains.In S2,the combined influence of the BLJ and synoptic-system-related low-level jet(SLLJ)increases the vertical wind shear and vertical vorticity,strengthening the rainstorm.In combination with the effect of topography,a warm and humid southwest flow continuously transports water vapor to farther north,resulting in a significant increase in rainfall over the study area(on the terrain’s windward slope).From S1 to S2,the altitude of a divergence center in the upper air decreases obviously.(2)The rainfalls in the two stages are both associated with the mesoscale convergence line(MCL)on the surface,and the wind field from the mesoscale outflow boundary(MOB)in S1 is in the same direction as the environmental winds.Due to a small area of convergence that is left behind the MOB,convection moves eastward quickly and causes a short duration of heavy rainfall.In S2,the convergence along the MOB is enhanced,which strengthens the rainfall and leads to strong outflows,further enhancing the surface convergence near the MOB and forming a positive feedback mechanism.It results in a slow motion of convection and a long duration of heavy rainfall.(3)In terms of microphysics,the center of a strong echo in S1 is higher than in S2.The warm-rain process of the oceanic type characterizes both stages,but the convective intensity in S2 is significantly stronger than that in S1,featuring bigger drop sizes and lower concentrations.It is mainly due to the strengthening of LLJs,which makes small cloud droplets lift to melting levels,enhancing the ice phase process(riming process),producing large amounts of graupel particles and enhancing the melting and collision processes as they fall,resulting in the increase of liquid water content(LWC)and the formation of large raindrops near the surface. 展开更多
关键词 low-level jet THERMODYNAMICS MICROPHYSICS heavy rain south China coast
下载PDF
Analysis of the Characteristics of the Low-level Jets in the Middle Reaches of the Yangtze River during the Mei-yu Season
8
作者 Chunguang CUI Wen ZHOU +5 位作者 Hao YANG Xiaokang WANG Yi DENG Xiaofang WANG Guirong XU Jingyu WANG 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2023年第4期711-724,共14页
Here,we analyze the characteristics and the formation mechanisms of low-level jets(LLJs)in the middle reaches of the Yangtze River during the 2010 mei-yu season using Wuhan station radiosonde data and the fifth genera... Here,we analyze the characteristics and the formation mechanisms of low-level jets(LLJs)in the middle reaches of the Yangtze River during the 2010 mei-yu season using Wuhan station radiosonde data and the fifth generation of the European Centre for Medium-Range Weather Forecasts(ERA5)reanalysis dataset.Our results show that the vertical structure of LLJs is characterized by a predominance of boundary layer jets(BLJs)concentrated at heights of 900-1200 m.The BLJs occur most frequently at 2300 LST(LST=UTC+8 hours)but are strongest at 0200 LST,with composite wind velocities>14 m s^(-1).Synoptic-system-related LLJs(SLLJs)occur most frequently at 0800 LST but are strongest at 1100LST,with composite wind velocities>12 m s^(-1).Both BLJs and SLLJs are characterized by a southwesterly wind direction,although the wind direction of SLLJs is more westerly,and northeasterly SLLJs occur more frequently than northeasterly BLJs.When Wuhan is south of the mei-yu front,the westward extension of the northwest Pacific subtropical high intensifies,and the low-pressure system in the eastern Tibetan Plateau strengthens,favoring the formation of LLJs,which are closely related to precipitation.The wind speeds on rainstorm days are greater than those on LLJ days.Our analysis of four typical heavy precipitation events shows the presence of LLJs at the center of the precipitation and on its southern side before the onset of heavy precipitation.BLJs were shown to develop earlier than SLLJs. 展开更多
关键词 mei-yu front boundary layer jets synoptic low-level jets heavy rainfall middle reaches of the Yangtze River
下载PDF
Personage Column: GONG Feili
9
《The Chinese-German Journal of Clinical Oncology》 CAS 2003年第4期5-5,共1页
Prof. Gong Feili was born and raised in Shanghai, China. He attended Sun Yat-sen Medical College, Guang zhou during 1962 to 1968, and received his M.D. degree there in 1968. After graduation, he worked as a physician ... Prof. Gong Feili was born and raised in Shanghai, China. He attended Sun Yat-sen Medical College, Guang zhou during 1962 to 1968, and received his M.D. degree there in 1968. After graduation, he worked as a physician in the Department of Internal Medicine of the Wugang Hospital, Wuhan, from 1968 to 1980. During that period of time, cases of leukemia drew his attention, and made 展开更多
关键词 in of been for GONG Feili personage Column
全文增补中
Effects of Kangfuxin Solution (康复新液) Combined with Low-level Laser on Cytokines and Immune Function in Patients with Radiation-induced Oral Mucositis
10
作者 董克臣 张萌 李松 《World Journal of Integrated Traditional and Western Medicine》 2023年第1期23-28,共6页
Objective:To investigate the effect of Kangfuxin Solution(康复新液)combined with low-level laser therapy(LLLT)on cytokines and immune function in patients with radiation-induced oral mucositis.Methods:There were 84 na... Objective:To investigate the effect of Kangfuxin Solution(康复新液)combined with low-level laser therapy(LLLT)on cytokines and immune function in patients with radiation-induced oral mucositis.Methods:There were 84 nasopharyngeal carcinoma patients with oral mucositis after intensity-modulated radiation therapy(IMRT)were randomly divided into the control group(CG)and the observation group(OG),with 42 cases in each group.The CG was given LLLT,and the OG was treated with Kangfuxin Solution in addition to LLLT for 10 consecutive days.The healing time of oral mucosa,mucositis grading,oral pain scores,cytokines(interleukin-6,interleukin-1βand tumor necrosis factor-α)and T lymphocyte subsets were compared between the 2 groups before and after treatment.Results:The healing time of oral mucosa in the OG was(6.8±1.4)d,which was significantly shorter than(8.6±1.9)d in the CG(t=4.943,P<0.01).After treatment,the grading of oral mucositis in the OG was better than that in the CG,with a statistically significant difference(Z=2.942,P<0.05).The oral pain scores of the OG was lower than that in the CG at different time points after treatment,and the difference was statistically significant(t=8.207,11.017,P<0.01).After treatment,the levels of IL-6,IL-1βand TNF-αin peripheral blood of the OG were significantly lower than those in the CG(t=5.217,2.775,4.053,P<0.01).There were statistically significant differences in CD4+,CD8+and CD4+/CD8+between the OG and the CG after treatment(t=5.692,6.093,3.658,P<0.01).Conclusion:Kangfuxin Solution combined with LLLT can significantly shorten the healing time of oral mucosal,reduce the grading of oral mucositis,relieve oral pain,reduce inflammatory response and improve the immune function of patients. 展开更多
关键词 Radiation-induced oral mucositis Nasopharyngeal carcinoma Kangfuxin Solution low-level laser therapy CYTOKINES Immune function
下载PDF
Assessment of Wet Season Precipitation in the Central United States by the Regional Climate Simulation of the WRFG Member in NARCCAP and Its Relationship with Large-Scale Circulation Biases 被引量:1
11
作者 Yating ZHAO Ming XUE +2 位作者 Jing JIANG Xiao-Ming HU Anning HUANG 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2024年第4期619-638,共20页
Assessment of past-climate simulations of regional climate models(RCMs)is important for understanding the reliability of RCMs when used to project future regional climate.Here,we assess the performance and discuss pos... Assessment of past-climate simulations of regional climate models(RCMs)is important for understanding the reliability of RCMs when used to project future regional climate.Here,we assess the performance and discuss possible causes of biases in a WRF-based RCM with a grid spacing of 50 km,named WRFG,from the North American Regional Climate Change Assessment Program(NARCCAP)in simulating wet season precipitation over the Central United States for a period when observational data are available.The RCM reproduces key features of the precipitation distribution characteristics during late spring to early summer,although it tends to underestimate the magnitude of precipitation.This dry bias is partially due to the model’s lack of skill in simulating nocturnal precipitation related to the lack of eastward propagating convective systems in the simulation.Inaccuracy in reproducing large-scale circulation and environmental conditions is another contributing factor.The too weak simulated pressure gradient between the Rocky Mountains and the Gulf of Mexico results in weaker southerly winds in between,leading to a reduction of warm moist air transport from the Gulf to the Central Great Plains.The simulated low-level horizontal convergence fields are less favorable for upward motion than in the NARR and hence,for the development of moist convection as well.Therefore,a careful examination of an RCM’s deficiencies and the identification of the source of errors are important when using the RCM to project precipitation changes in future climate scenarios. 展开更多
关键词 NARCCAP Central United States PRECIPITATION low-level jet large-scale environment diurnal variation
下载PDF
智媒时代网络人士互联网行为的柔性治理研究
12
作者 李建飞 刘念 《陕西行政学院学报》 2024年第2期29-33,共5页
智媒技术语境下,国内外舆论环境日益复杂、社会表达日趋多样,探讨如何强化网络人士群体的互联网行为柔性治理建设,是有效维护社会稳定与国家主流意识形态安全,不断推进新时代一线统战工作深入向前的重要议题。当前网络人士互联网行为的... 智媒技术语境下,国内外舆论环境日益复杂、社会表达日趋多样,探讨如何强化网络人士群体的互联网行为柔性治理建设,是有效维护社会稳定与国家主流意识形态安全,不断推进新时代一线统战工作深入向前的重要议题。当前网络人士互联网行为的总体特征已显现,从主场优势遭消解、话语权威受冲击、实践效果减弱和引领力度受削减等维度分析,网络统战工作面临诸多复杂的舆论风险与现实困境。智媒时代复杂舆论环境下,网络人士的互联网统战工作面临着传播方式上“宣传有余,互动不足”、传播内容上“同质化有余,吸引力不足”、传播对象上“宽广度有余,精准度不足”以及考核指标上“问责性有余,激励性不足”等问题。应从思想政治引领、丰富组织活动、创新管理体制、坚持内容为王、紧抓技术红利和完善考核机制等层面,强化智媒时代复杂舆论环境下网络人士互联网统战工作的具体治理措施。 展开更多
关键词 智媒时代 网络人士 互联网 柔性治理
下载PDF
统一战线深化服务全过程人民民主的若干对策性思考
13
作者 程竹汝 刘自勋 《上海市社会主义学院学报》 2024年第3期83-91,共9页
党的二十大报告将“巩固和发展最广泛的爱国统一战线”作为发展全过程人民民主的内在要求和战略布局之一,蕴含着统一战线与发展全过程人民民主之间深刻的内在联系,以坚实的大团结大联合的统战优势服务全过程人民民主,正是这种内在联系... 党的二十大报告将“巩固和发展最广泛的爱国统一战线”作为发展全过程人民民主的内在要求和战略布局之一,蕴含着统一战线与发展全过程人民民主之间深刻的内在联系,以坚实的大团结大联合的统战优势服务全过程人民民主,正是这种内在联系的规律性内涵和实践要求。统一战线深化服务全过程人民民主之实践,应着力激发民主党派作为中国特色社会主义参政党的功能;提升新的社会阶层人士政治参与的能力和参与度;夯实民营企业家作为社会主义建设者的政治地位;同时,强化基层统战和网络统战,拓展统一战线服务全过程人民民主的多维渠道。 展开更多
关键词 统一战线 全过程人民民主 民主党派 新的社会阶层人士 非公经济人士
下载PDF
论《世说新语》的“语料体小说”性质
14
作者 陶成涛 《渭南师范学院学报》 2024年第1期79-84,共6页
《世说新语》是中国古代“志人小说”的代表。相比于其他“志人小说”,《世说新语》具有独特的玄学文化特征。自东晋中期开始,世族阶层纯粹的思辨性的谈玄活动逐渐被其他形式的玄学活动取代,这个短暂的文化变迁时期和后来的文化追怀时... 《世说新语》是中国古代“志人小说”的代表。相比于其他“志人小说”,《世说新语》具有独特的玄学文化特征。自东晋中期开始,世族阶层纯粹的思辨性的谈玄活动逐渐被其他形式的玄学活动取代,这个短暂的文化变迁时期和后来的文化追怀时期合称为“后玄学时代”。在“后玄学时代”,谢灵运的山水诗成为新的内容,而比谢灵运稍早,一种在世族中风靡的具有语料传播功能的作品应需而生,《语林》《郭子》正是这类作品的代表。这些“语料”迅速成为世族子弟领会玄学精神、学习名士风范的指南。《世说新语》正是对这种文化风尚的总结。结合现代文学意义的“小说”定义,《世说新语》可称为“语料体小说”。 展开更多
关键词 《世说新语》 志人小说 语料体 文化生成
下载PDF
New therapeutic options for persistent low-level viremia in patients with chronic hepatitis B virus infection:Increase of entecavir dosage 被引量:18
15
作者 Guo-Qing Yin Jun Li +2 位作者 Bei Zhong Yong-Fong Yang Mao-Rong Wang 《World Journal of Gastroenterology》 SCIE CAS 2021年第8期666-676,共11页
Chronic hepatitis B virus(HBV)infection(CHB)is a public health concern worldwide.Current therapies utilizing nucleos(t)ide analogs(NA)have not resulted in a complete cure for CHB.Furthermore,patients on long-term NA t... Chronic hepatitis B virus(HBV)infection(CHB)is a public health concern worldwide.Current therapies utilizing nucleos(t)ide analogs(NA)have not resulted in a complete cure for CHB.Furthermore,patients on long-term NA treatment often develop low-level viremia(LLV).Persistent LLV,in addition to causing the progression of liver disease or hepatocellular carcinoma,may shed light on the current plight of NA therapy.Here,we review the literature on LLV,NA treatment,and various doses of entecavir to find a strategy for improving the efficacy of this antiviral agent.For LLV patients,three therapeutic options are available,switching to another antiviral monotherapy,interferon-αswitching therapy,and continuing monotherapy.In real-world clinical practice,entecavir overdose has been used in antiviral therapy for CHB patients with NA refractory and persistent LLV,which encouraged us to conduct further in-depth literature survey on dosage and duration related entecavir studies.The studies of pharmacodynamics and pharmacokinetics show that entecavir has the maximal selected index for safety,and has great potential in inhibiting HBV replication,in all of the NAs.In the particular section of the drug approval package published by the United States Food and Drug Administration,entecavir doses 2.5-20 mg/d do not increase adverse events,and entecavir doses higher than 1.0 mg/d might improve the antiviral efficacy.The literature survey led us to two suggestions:(1)Increasing entecavir dose to 1.0 mg/d for the treatment of NA naïve patients with HBV DNA>2×106 IU/mL is feasible and would provide better prognosis;and(2)Further research is needed to assess the long-term toxic effects of higher entecavir doses(2.5 and 5.0 mg/d),which may prove beneficial in treating patients with prior NA treatment,partial virological response,or LLV state. 展开更多
关键词 Chronic hepatitis B virus infection low-level viremia Therapeutic options ENTECAVIR DOSE Efficacy
下载PDF
Role of the Nocturnal Low-level Jet in the Formation of the Morning Precipitation Peak over the Dabie Mountains 被引量:16
16
作者 Peiling FU Kefeng ZHU +2 位作者 Kun ZHAO Bowen ZHOU Ming XUE 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2019年第1期15-28,共14页
The diurnal variation of precipitation over the Dabie Mountains(DBM) in eastern China during the 2013 mei-yu season is investigated with forecasts of a regional convection-permitting model. Simulated precipitation is ... The diurnal variation of precipitation over the Dabie Mountains(DBM) in eastern China during the 2013 mei-yu season is investigated with forecasts of a regional convection-permitting model. Simulated precipitation is verified against surface rain-gauge observations. The observed morning precipitation peak on the windward(relative to the prevailing synoptic-scale wind) side of the DBM is reproduced with good spatial and temporal accuracy. The interaction between the DBM and a nocturnal boundary layer low-level jet(BLJ) due to the inertial oscillation mechanism is shown to be responsible for this precipitation peak. The BLJ is aligned with the lower-level southwesterly synoptic-scale flow that carries abundant moisture.The BLJ core is established at around 0200 LST upwind of the mountains. It moves towards the DBM and reaches maximum intensity at about 70 km ahead of the mountains. When the BLJ impinges upon the windward side of the DBM in the early morning, mechanical lifting of moist air leads to condensation and subsequent precipitation. 展开更多
关键词 nocturnal boundary layer low-level jet diurnal variation PRECIPITATION Dabie Mountains meiyu season
下载PDF
Integration of Low-level Waste Heat Recovery and Liquefied Nature Gas Cold Energy Utilization 被引量:16
17
作者 白菲菲 张早校 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2008年第1期95-99,共5页
Two novel thermal cycles based on Brayton cycle and Rankine cycle are proposed, respectively, which integrate the recovery of low-level waste heat and Liquefied Nature Gas (LNG) cold energy utilization for power gen... Two novel thermal cycles based on Brayton cycle and Rankine cycle are proposed, respectively, which integrate the recovery of low-level waste heat and Liquefied Nature Gas (LNG) cold energy utilization for power generation. Cascade utilization of energy is realized in the two thermal cycles, where low-level waste heat,low-temperature exergy and pressure exergy of LNG are utilized efficiently through the system synthesis. The simulations are carried out using the commercial Aspen Plus 10.2, and the results are analyzed. Compared with the conventional Brayton cycle and Rankine cycle, the two novel cycles bring 60.94% and 60% in exergy efficiency, respectively and 53.08% and 52.31% in thermal efficiency, respectively. 展开更多
关键词 recovery of low-level waste heat LNG cold energy utilization power generation cascade utilization
下载PDF
Nocturnal Low-levelWinds and Their Impacts on Particulate Matter over the Beijing Area 被引量:2
18
作者 Yong CHEN Junling AN +5 位作者 Yele SUN Xiquan WANG Yu QU Jingwei ZHANG Zifa WANG Jing DUAN 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2018年第12期1455-1468,共14页
Three-month wind profiles, 260 m PM_1 concentrations [i.e., particulate matter(PM) with an aerodynamic diameter ≤1μm], and carrier-to-noise ratio data at two Beijing sites 55 km apart(urban and suburban) were collec... Three-month wind profiles, 260 m PM_1 concentrations [i.e., particulate matter(PM) with an aerodynamic diameter ≤1μm], and carrier-to-noise ratio data at two Beijing sites 55 km apart(urban and suburban) were collected to analyze the characteristics of low-level nocturnal wind and PM in autumn and winter. Three mountain-plain wind events with wind shear were selected for analysis. The measurements indicated that the maximum wind speeds of the northerly weak low-level jet(LLJ) below 320 m at the suburban site were weaker than those at the urban site, and the LLJ heights and depths at the suburban site were lower than those at the urban site. The nocturnal 140 m mean vertical velocities and the variations in vertical velocity at the urban site were larger than those at the suburban site. A nocturnal breeze with a weak LLJ of ~3 m s^(-1) noticeably offset nocturnal PM transport due to southerly flow and convergence within the northern urban area of Beijing. Characteristics of the nocturnal LLJ, such as start-up time, structure, intensity, and duration, were important factors in determining the decrease in the nocturnal horizontal range and site-based low-level variations in PM. 展开更多
关键词 WEAK low-level jet WIND direction SHEAR WIND lidar low-level PM1
下载PDF
Low-Level Jets over Southeast China: The Warm Season Climatology of the Summer of 2003 被引量:5
19
作者 LIU Hong-Bo LI Li-Juan WANG Bin 《Atmospheric and Oceanic Science Letters》 2012年第5期394-400,共7页
The southwesterly low-level jet (LLJ) over southeast China in the summer of 2003 is analyzed in this study. The analysis is based on the National Centers for Environmental Prediction (NCEP) Final (FNL) operation... The southwesterly low-level jet (LLJ) over southeast China in the summer of 2003 is analyzed in this study. The analysis is based on the National Centers for Environmental Prediction (NCEP) Final (FNL) operational global analysis data on 1.0-1.0-degree grids at 6-h intervals. The major criteria for choosing the LLJ ineluded the following: a maximum wind speed equal to or greater than 12.0 m s-1, a wind direction of between 180° and 270°, and the height of wind maximum at 900-700 hPa, not confined to single pressure level. The results show that the LLJs over southeast China dominate at 850 and 800 hPa. These LLJs are closely associated with the topography of this area and tend to locate regions with large terrain gradients, including the northeastern and eastem Yunnan-Guizhou Plateau. Under the influence of mid-latitude westerly winds, the LLJs above 750 hPa move northward to the Yangtze-Huai River Basin. Com- pared to the ten-year (2000-2009) mean climate condi- tions, the LLJs in the warm season of summer 2003 were exceptionally active and strong, as reflected by the posi- tive anomalies of LLJ occurrence numbers and wind speed. In addition, the 2003 LLJs showed strong diurnal variation, especially at pressure levels below 800 hPa. The majority of the LLJs appeared between midnight and the early moming hours (before 8 a.m.). Finally, the summary of LLJ grid numbers indicates that more than 80% of LLJs in June and July 2003 occurred within the 33-d rainy period. Thus, these LLJs are directly related to the anomalously heavy rainfall in the Yangtze-Huai River Basin. 展开更多
关键词 low-level jet ANOMALY diurnal variation heavy rainfall
下载PDF
Advanced topics on RF amplitude and phase detection for low-level RF systems 被引量:4
20
作者 Zhe-Qiao Geng Roger Kalt 《Nuclear Science and Techniques》 SCIE CAS CSCD 2019年第10期9-20,共12页
Low-level radio frequency(LLRF)systems stabilize the electromagnetic field in the RF cavities used for beam acceleration in particle accelerators.Reliable,accurate,and precise detection of RF amplitude and phase is pa... Low-level radio frequency(LLRF)systems stabilize the electromagnetic field in the RF cavities used for beam acceleration in particle accelerators.Reliable,accurate,and precise detection of RF amplitude and phase is particularly important to achieve high field stability for pulsed accelerators of free-electron lasers(FEL).The digital LLRF systems employ analog-to-digital converters to sample the frequency down-converted RF signal and use digital demodulation algorithms to calculate the RF amplitude and phase.Different sampling strategies and demodulation algorithms have been developed for these purposes and are introduced in this paper.This article focuses on advanced topics concerning RF detection,including accurate RF transient measurement,wideband RF detection,and RF detection with an asynchronous trigger,local oscillator,or clock.The analysis is based on the SwissFEL measurements,but the algorithms introduced are general for RF signal detection in particle accelerators. 展开更多
关键词 low-level RADIO frequency RF detector RF TRANSIENT DETECTION ASYNCHRONOUS RF DETECTION
下载PDF
上一页 1 2 20 下一页 到第
使用帮助 返回顶部