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A Low-Power-Consumption 9bit 10MS/s Pipeline ADC for CMOS Image Sensors 被引量:1
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作者 朱天成 姚素英 李斌桥 《Journal of Semiconductors》 EI CAS CSCD 北大核心 2007年第12期1924-1929,共6页
A low-power-consumption 9bit 10MS/s pipeline ADC,used in a CMOS image sensor,is proposed. In the design, the decrease of power consumption is achieved by applying low-power-consumption and large-output-swing amplifier... A low-power-consumption 9bit 10MS/s pipeline ADC,used in a CMOS image sensor,is proposed. In the design, the decrease of power consumption is achieved by applying low-power-consumption and large-output-swing amplifiers with gain boost structure, and biasing all the cells with the same voltage bias source, which requires careful layout design and large capacitors. In addition,capacitor array DAC is also applied to reduce power consumption,and low threshold voltage MOS transistors are used to achieve a large signal processing range. The ADC was implemented in a 0.18μm 4M-1 P CMOS process,and the experimental results indicate that it consumes only 7mW, which is much less than general pipeline ADCs. The ADC was used in a 300000 pixels CMOS image sensor. 展开更多
关键词 pipeline ADC low power design CMOS image sensor large signal processing range
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On-Chip Micro Temperature Controllers Based on Freestanding Thermoelectric Nano Films for Low-Power Electronics
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作者 Qun Jin Tianxiao Guo +4 位作者 Nicolas Perez Nianjun Yang Xin Jiang Kornelius Nielsch Heiko Reith 《Nano-Micro Letters》 SCIE EI CAS CSCD 2024年第7期98-108,共11页
Multidimensional integration and multifunctional com-ponent assembly have been greatly explored in recent years to extend Moore’s Law of modern microelectronics.However,this inevitably exac-erbates the inhomogeneity ... Multidimensional integration and multifunctional com-ponent assembly have been greatly explored in recent years to extend Moore’s Law of modern microelectronics.However,this inevitably exac-erbates the inhomogeneity of temperature distribution in microsystems,making precise temperature control for electronic components extremely challenging.Herein,we report an on-chip micro temperature controller including a pair of thermoelectric legs with a total area of 50×50μm^(2),which are fabricated from dense and flat freestanding Bi2Te3-based ther-moelectric nano films deposited on a newly developed nano graphene oxide membrane substrate.Its tunable equivalent thermal resistance is controlled by electrical currents to achieve energy-efficient temperature control for low-power electronics.A large cooling temperature difference of 44.5 K at 380 K is achieved with a power consumption of only 445μW,resulting in an ultrahigh temperature control capability over 100 K mW^(-1).Moreover,an ultra-fast cooling rate exceeding 2000 K s^(-1) and excellent reliability of up to 1 million cycles are observed.Our proposed on-chip temperature controller is expected to enable further miniaturization and multifunctional integration on a single chip for microelectronics. 展开更多
关键词 Temperature control low-power electronics On-chip micro temperature controller Freestanding thermoelectric nano films Temperature-sensitive components
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Low-power system model for quantum entangled photon-pair source
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作者 FENG Tianxuan ZHANG Hanyi +3 位作者 FAN Rong MA Honghao DONG Mengcheng LI Lijing 《Journal of Systems Engineering and Electronics》 SCIE CSCD 2024年第5期1287-1294,共8页
The quantum entangled photon-pair source,as an essential component of optical quantum systems,holds great potential for applications such as quantum teleportation,quan-tum computing,and quantum imaging.The current wor... The quantum entangled photon-pair source,as an essential component of optical quantum systems,holds great potential for applications such as quantum teleportation,quan-tum computing,and quantum imaging.The current workhorse technique for preparing photon pairs involves performing spon-taneous parametric down conversion(SPDC)in bulk nonlinear crystals.However,the current power consumption and cost of preparing entangled photon-pair sources are relatively high,pos-ing challenges to their integration and scalability.In this paper,we propose a low-power system model for the quantum entan-gled photon-pair source based on SPDC theory and phase matching technology.This model allows us to analyze the per-formance of each module and the influence of component cha-racteristics on the overall system.In our experimental setup,we utilize a 5 mW laser diode and a typical type-II barium metabo-rate(BBO)crystal to prepare an entangled photon-pair source.The experimental results are in excellent agreement with the model,indicating a significant step towards achieving the goal of low-power and low-cost entangled photon-pair sources.This achievement not only contributes to the practical application of quantum entanglement lighting,but also paves the way for the widespread adoption of optical quantum systems in the future. 展开更多
关键词 low-power system model optical quantum system entangled photon-pair source spontaneous parametric down conversion
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Low-power SiPM readout BETA ASIC for space applications
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作者 Anand Sanmukh Sergio Gómez +9 位作者 Albert Comerma Joan Mauricio Rafel Manera Andreu Sanuy Daniel Guberman Roger Catala Albert Espinya Marina Orta Oscar de la Torre David Gascon 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2024年第3期153-169,共17页
The BETA application-specific integrated circuit(ASIC)is a fully programmable chip designed to amplify,shape and digitize the signal of up to 64 Silicon photomultiplier(SiPM)channels,with a power consumption of approx... The BETA application-specific integrated circuit(ASIC)is a fully programmable chip designed to amplify,shape and digitize the signal of up to 64 Silicon photomultiplier(SiPM)channels,with a power consumption of approximately~1 mW/channel.Owing to its dual-path gain,the BETA chip is capable of resolving single photoelectrons(phes)with a signal-to-noise ratio(SNR)>5 while simultaneously achieving a dynamic range of~4000 phes.Thus,BETA can provide a cost-effective solution for the readout of SiPMs in space missions and other applications with a maximum rate below 10 kHz.In this study,we describe the key characteristics of the BETA ASIC and present an evaluation of the performance of its 16-channel version,which is implemented using 130 nm technology.The ASIC also contains two discriminators that can provide trigger signals with a time jitter down to 400 ps FWHM for 10 phes.The linearity error of the charge gain measurement was less than 2%for a dynamic range as large as 15 bits. 展开更多
关键词 Radiation detectors Silicon photomultipliers Photon sensors Front-end electronics Mixed-mode ASICs Space technology
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Force and impulse multi-sensor based on flexible gate dielectric field effect transistor
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作者 Chao Tan Junling Lü +3 位作者 Chunchi Zhang Dong Liang Lei Yang Zegao Wang 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CAS 2025年第1期214-220,共7页
Nowadays,force sensors play an important role in industrial production,electronic information,medical health,and many other fields.Two-dimensional material-based filed effect transistor(2D-FET)sensors are competitive ... Nowadays,force sensors play an important role in industrial production,electronic information,medical health,and many other fields.Two-dimensional material-based filed effect transistor(2D-FET)sensors are competitive with nano-level size,lower power consumption,and accurate response.However,few of them has the capability of impulse detection which is a path function,expressing the cumulative effect of the force on the particle over a period of time.Herein we fabricated the flexible polymethyl methacrylate(PMMA)gate dielectric MoS_(2)-FET for force and impulse sensor application.We systematically investigated the responses of the sensor to constant force and varying forces,and achieved the conversion factors of the drain current signals(I_(ds))to the detected impulse(I).The applied force was detected and recorded by I_(ds)with a low power consumption of~30 nW.The sensitivity of the device can reach~8000%and the 4×1 sensor array is able to detect and locate the normal force applied on it.Moreover,there was almost no performance loss for the device as left in the air for two months. 展开更多
关键词 flexible gate dielectric transistor force sensor impulse sensor force sensor array
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A Low-Power CMOS Analog Front-End IC with Adjustable On-Chip Filters for Biosensors
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作者 Donald Y. C. Lie Vighnesh Das +2 位作者 Weibo Hu Yenting Liu Tam Nguyen 《Open Journal of Applied Biosensor》 2013年第4期104-111,共8页
This paper presents a low-power CMOS analog front-end (AFE) IC designed with a selectable on-chip dual AC/DC- coupled paths for bio-sensor applications. The DC-coupled path can be selected to sense a biosignal with us... This paper presents a low-power CMOS analog front-end (AFE) IC designed with a selectable on-chip dual AC/DC- coupled paths for bio-sensor applications. The DC-coupled path can be selected to sense a biosignal with useful DC information, and the AC-coupled path can be selected for sensing the AC content of the biosignal by attenuating the unwanted DC component. The AFE IC includes a DC-coupled instrumentation amplifier (INA), two variable-gain 1st-order low pass filters (LPF) with tunable cut-off frequencies, a fixed gain 2nd-order Sallen-Key high-pass filter (HPF) with tunable cut-off frequencies, a buffer and an 8-bit differential successive approximation register (SAR) ADC. The entire AFE channel is designed and fabricated in a proprietary 0.35-μm CMOS technology. Excluding an external buffer needed to properly drive the ADC, the measured AFE IC consumes only 2.37 μA/channel with an input referred noise of ~40 μVrms in [1 Hz, 1 kHz], and successfully displays proper ECG (electrocardiogram) and electrogram (EGM) waveforms for QRS peaks detection. We expect that the low-power dual-path design of this AFE IC can enable it to periodically record both the AC and the DC signals for proper sensing and calibration for various bio-sensing applications. 展开更多
关键词 low-power CMOS Bio-sensor Applications DC-COUPLED
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Design of low-offset low-power CMOS amplifier for biosensor application
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作者 Jin-Yong Zhang Lei Wang Bin Li 《Journal of Biomedical Science and Engineering》 2009年第7期538-542,共5页
A compacted and low-offset low-power CMOS am- plifier for biosensor application is presented in this paper. It includes a low offset Op-Amp and a high precision current reference. With a novel continuous-time DC offse... A compacted and low-offset low-power CMOS am- plifier for biosensor application is presented in this paper. It includes a low offset Op-Amp and a high precision current reference. With a novel continuous-time DC offset rejection scheme, the IC achieves lower offset voltage and lower power consumption compared to previous designs. This configuration rejects large DC offset and drift that exist at the skin-electrode interface without the need of external components. The proposed amplifier has been implemented in SMIC 0.18-μm 1P6M CMOS technol-ogy, with an active silicon area of 100 μm by 120 μm. The back-annotated simulation results demonstrated the circuit features the systematic offset voltage less than 80 μV, the offset drift about 0.27 μV/℃ for temperature ranging from –30℃ to 100℃ and the total power dissipation consumed as low as 37.8 μW from a 1.8 V single supply. It dedicated to monitor low amplitude biomedical signals recording. 展开更多
关键词 BIOMEDICAL Integrated CIRCUIT CMOS Ampli- fier Low-Offset and low-power DC OFFSET REJECTION Bio-medical sensor
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Bioinspired Passive Tactile Sensors Enabled by Reversible Polarization of Conjugated Polymers
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作者 Feng He Sitong Chen +3 位作者 Ruili Zhou Hanyu Diao Yangyang Han Xiaodong Wu 《Nano-Micro Letters》 SCIE EI CAS 2025年第1期361-377,共17页
Tactile perception plays a vital role for the human body and is also highly desired for smart prosthesis and advanced robots.Compared to active sensing devices,passive piezoelectric and triboelectric tactile sensors c... Tactile perception plays a vital role for the human body and is also highly desired for smart prosthesis and advanced robots.Compared to active sensing devices,passive piezoelectric and triboelectric tactile sensors consume less power,but lack the capability to resolve static stimuli.Here,we address this issue by utilizing the unique polarization chemistry of conjugated polymers for the first time and propose a new type of bioinspired,passive,and bio-friendly tactile sensors for resolving both static and dynamic stimuli.Specifically,to emulate the polarization process of natural sensory cells,conjugated polymers(including poly(3,4-ethylenedioxythiophen e):poly(styrenesulfonate),polyaniline,or polypyrrole)are controllably polarized into two opposite states to create artificial potential differences.The controllable and reversible polarization process of the conjugated polymers is fully in situ characterized.Then,a micro-structured ionic electrolyte is employed to imitate the natural ion channels and to encode external touch stimulations into the variation in potential difference outputs.Compared with the currently existing tactile sensing devices,the developed tactile sensors feature distinct characteristics including fully organic composition,high sensitivity(up to 773 mV N^(−1)),ultralow power consumption(nW),as well as superior bio-friendliness.As demonstrations,both single point tactile perception(surface texture perception and material property perception)and two-dimensional tactile recognitions(shape or profile perception)with high accuracy are successfully realized using self-defined machine learning algorithms.This tactile sensing concept innovation based on the polarization chemistry of conjugated polymers opens up a new path to create robotic tactile sensors and prosthetic electronic skins. 展开更多
关键词 Passive tactile sensors Reversible polarization of conjugated polymers Tactile perception Machine learning algorithm Object recognition
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A low-power high-quality CMOS image sensor using 1.5 V 4T pinned photodiode and dual-CDS column-parallel single-slope ADC
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作者 Wenjing Xu Jie Chen +3 位作者 Zhangqu Kuang Li Zhou Ming Chen Chengbin Zhang 《Journal of Semiconductors》 EI CAS CSCD 2022年第8期53-59,共7页
This paper presents a low-power high-quality CMOS image sensor(CIS)using 1.5 V 4T pinned photodiode(4T-PPD)and dual correlated double sampling(dual-CDS)column-parallel single-slope ADC.A five-finger shaped pixel layer... This paper presents a low-power high-quality CMOS image sensor(CIS)using 1.5 V 4T pinned photodiode(4T-PPD)and dual correlated double sampling(dual-CDS)column-parallel single-slope ADC.A five-finger shaped pixel layer is proposed to solve image lag caused by low-voltage 4T-PPD.Dual-CDS is used to reduce random noise and the nonuniformity between columns.Dual-mode counting method is proposed to improve circuit robustness.A prototype sensor was fabricated using a 0.11μm CMOS process.Measurement results show that the lag of the five-finger shaped pixel is reduced by 80%compared with the conventional rectangular pixel,the chip power consumption is only 36 mW,the dynamic range is 67.3 dB,the random noise is only 1.55 e^(-)_(rms),and the figure-of-merit is only 1.98 e^(-)·nJ,thus realizing low-power and high-quality imaging. 展开更多
关键词 CMOS image sensor 4T pinned photodiode single-slope ADC correlated double sample counting method
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Key Environmental Factors Monitoring System of Low-power Greenhouse Based on WSN Technology
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作者 柳军 陶建平 吕晓兰 《Agricultural Science & Technology》 CAS 2016年第2期449-452,共4页
A low-power environmental monitoring system based on WSN technology is proposed to effectively monitor the environmental status and ensure the healthy growth of greenhouse crops in the greenhouse. The system performs ... A low-power environmental monitoring system based on WSN technology is proposed to effectively monitor the environmental status and ensure the healthy growth of greenhouse crops in the greenhouse. The system performs dynamic mon- itoring on the environmental data of temperature, humidity, illumination, soil tempera- ture and humidity of the greenhouse, and it reduces the energy consumption by us- ing solar energy and lithium battery as the power supply mode and dynamic power management algorithm combined with improved routing protocol. Stable and reliable, the system could effectively monitor the key environmental factors in the green- house, making it of certain promotion value. 展开更多
关键词 Environmental monitoring GREENHOUSE Wireless sensor network WSN technology Key factor
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A kind of low-power 10 Gbit/s CMOS 1∶4 demultiplexer 被引量:1
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作者 蒋俊洁 冯军 +2 位作者 李有慧 胡庆生 熊明珍 《Journal of Southeast University(English Edition)》 EI CAS 2006年第1期1-4,共4页
A 10 Gbit/s 1:4 demultiplexer(DEMUX) fabricated in 0. 18 μm CMOS (complementary metal-oxidesemiconductor transistor) technology for optical-fiber-link is presented. The system is constructed in tree-type structu... A 10 Gbit/s 1:4 demultiplexer(DEMUX) fabricated in 0. 18 μm CMOS (complementary metal-oxidesemiconductor transistor) technology for optical-fiber-link is presented. The system is constructed in tree-type structure and it includes a high-speed 1 : 2 DEMUX, two low-speed 1 : 2 DEMUXs, a divider, and input and output buffers for data and dock. To improve the circuit performance and reduce the power consumption, a latch structure with a common-gate topology and a single clock phase is employed in the high-speed 1 : 2 DEMUX and the 5 GHz 1 : 2 on-chip frequency divider, while dynamic CMOS logic is adopted in the low-speed l : 2 DEMUXs. Measured results at 10 Gbit/s by 23^31 -1 pseudo random bit sequences (PRBS) via on-wafer testing indicate that it can work well with a power dissipation of less than 100 mW at 1.8 V supply voltage. The die area of the DEMUX is 0. 65 mm × 0. 75 mm. 展开更多
关键词 optical communication CMOS demultiplexer (DEMUX) low-power
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A 2.4-GHz-Low-Power CMOS RF Transmitter for IEEE 802.15.4 Standard 被引量:2
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作者 Mohen Nasri Amina Msolli +1 位作者 Abdelhamid Helali Hassen Maaref 《Wireless Sensor Network》 2012年第6期173-176,共4页
This paper presents the experimental results of a low-power RF transmitter for 2.4-GHz-band IEEE 802.15.4 standard in 0.18-μm CMOS technology. In order to make an adaptive RF transmitter, several factors must be cons... This paper presents the experimental results of a low-power RF transmitter for 2.4-GHz-band IEEE 802.15.4 standard in 0.18-μm CMOS technology. In order to make an adaptive RF transmitter, several factors must be considered. The most important factors are performances, power consumption, output power, noise factor, and cost. The RF transmitter comprises a quadrature passive mixer, and a power amplifier. The proposed RF transmitter consumes only 10.8-mW under a supply voltage of 1.8-V. 展开更多
关键词 IEEE 802.15.4 TRANSMITTER CMOS LOW COST LOW Power Wireless sensor Network
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Low-power laser irradiation promotes the proliferation and osteogenic differentiation of human periodontal ligament cells via cyclic adenosine monophosphate 被引量:5
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作者 Jyun-Yi Wu Chia-Hsin Chen +3 位作者 Li-Yin Yeh Ming-Long Yeh Chun-Chan Ting Yan-Hsiung Wang 《International Journal of Oral Science》 SCIE CAS CSCD 2013年第2期85-91,共7页
Retaining or improving periodontal ligament (PDL) function is crucial for restoring periodontal defects. The aim of this study was to evaluate the physiological effects of low-power laser irradiation (LPLI) on the... Retaining or improving periodontal ligament (PDL) function is crucial for restoring periodontal defects. The aim of this study was to evaluate the physiological effects of low-power laser irradiation (LPLI) on the proliferation and osteogenic differentiation of human PDL (hPDL) cells. Cultured hPDL cel Is were irradiated (660 nm) daily with doses of O, 1, 2 or 4 J .cm-2. Cell proliferation was evaluated by the 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide (MTT) assay, and the effect of LPLI on osteogenic differentiation was assessed by Alizarin Red S staining and alkaline phosphatase (ALP) activity. Additionally, osteogenic marker gene expression was confirmed by real-time reverse transcription-polymerase chain reaction (RT-PCR). Our data showed that LPLI at a dose of 2 J.cm-2 significantly promoted hPDL cell proliferation at days 3 and 5. In addition, LPLI at energy doses of 2 and 4 J.cm-2 showed potential osteogenic capacity, as it stimulated ALP activity, calcium deposition, and osteogenic gene expression. We also showed that cyclic adenosine monophosphate (cAMP) is a critical regulator of the LPLI-mediated effects on hPDL cells. This study shows that LPLI can promote the proliferation and osteogenic differentiation of hPDL cells. These results suggest the potential use of LPLI in clinical applications for periodontal tissue regeneration. 展开更多
关键词 cell proliferation cyclic adenosine monophosphate human periodontal ligament cells low-power laser irradiation osteogenic differentiation
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Modelling Study to Compare the Flow and Heat Transfer Characteristics of Low-Power Hydrogen,Nitrogen and Argon Arc-Heated Thrusters 被引量:5
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作者 王海兴 陈熙 +3 位作者 潘文霞 A.B.MURPHY 耿金越 贾少霞 《Plasma Science and Technology》 SCIE EI CAS CSCD 2010年第6期692-701,共10页
A modelling study is performed to compare the plasma flow and heat transfer characteristics of low-power arc-heated thrusters (arcjets) for three different propellants: hydrogen, nitrogen and argon. The all-speed S... A modelling study is performed to compare the plasma flow and heat transfer characteristics of low-power arc-heated thrusters (arcjets) for three different propellants: hydrogen, nitrogen and argon. The all-speed SIMPLE algorithm is employed to solve the governing equations, which take into account the effects of compressibility, Lorentz force and Joule heating, as well as the temperature- and pressure-dependence of the gas properties. The temperature, velocity and Mach number distributions calculated within the thruster nozzle obtained with different propellant gases are compared for the same thruster structure, dimensions, inlet-gas stagnant pressure and arc currents. The temperature distributions in the solid region of the anode-nozzle wall are also given. It is found that the flow and energy conversion processes in the thruster nozzle show many similar features for all three propellants. For example, the propellant is heated mainly in the near-cathode and constrictor region, with the highest plasma temperature appearing near the cathode tip; the flow transition from the subsonic to supersonic regime occurs within the constrictor region; the highest axial velocity appears inside the nozzle; and most of the input propellant flows towards the thruster exit through the cooler gas region near the anode-nozzle wall. However, since the properties of hydrogen, nitrogen and argon, especially their molecular weights, specific enthMpies and thermal conductivities, are different, there are appreciable differences in arcjet performance. For example, compared to the other two propellants, the hydrogen arcjet thruster shows a higher plasma temperature in the arc region, and higher axial velocity but lower temperature at the thruster exit. Correspondingly, the hydrogen arcjet thruster has the highest specific impulse and arc voltage for the same inlet stagnant pressure and arc current. The predictions of the modelling are compared favourably with available experimental results. 展开更多
关键词 low-power arcjet plasma flow and heat transfer numerical modelling propellant-type effects
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EXPERIMENTAL STUDY ON MACRO AND MICRO-STRUCTURE OF METALLIC PARTS BUILT BY LOW-POWER LASER CLADDING 被引量:2
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作者 LiuJichang LiLijun 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2005年第2期263-266,共4页
A low-power CO_2 laser is used to deposit Fe powder and mixture of Fe andcarbon powder on substrates respectively, and the macro and micro-structure of the formed samplesare investigated. It is demonstrated that most ... A low-power CO_2 laser is used to deposit Fe powder and mixture of Fe andcarbon powder on substrates respectively, and the macro and micro-structure of the formed samplesare investigated. It is demonstrated that most grains of these samples are equi-axed. This isderived from the high nucleation velocity in the shallow melt pool besides rapid solidification ofthe liquid-state alloy or metal. Bainitic structure, combination of pearlite and ferrite structureand ferrite structure are seen respectively in the samples involving various amounts of carbon owingto no martensitic transformation in these small samples. 展开更多
关键词 Laser cladding forming MICRO-STRUCTURE low-power laser
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Transplantation of low-power laser-irradiated olfactory ensheathing cells to promote repair of spinal cord injury in rats 被引量:3
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作者 Haoxian Chen Xinfeng Zheng +3 位作者 Weibin Sheng Qin Wei Tao Jiang Gele Jin 《Neural Regeneration Research》 SCIE CAS CSCD 2009年第3期171-177,共7页
BACKGROUND: Previous studies have demonstrated that low-power laser (LPL) irradiation can promote the regeneration of peripheral nerves and central nerves, as well as influence cellular proliferation. Therefore, it... BACKGROUND: Previous studies have demonstrated that low-power laser (LPL) irradiation can promote the regeneration of peripheral nerves and central nerves, as well as influence cellular proliferation. Therefore, it is thought to be a potential treatment for spinal cord injury. OBJECTIVE: Utilizing histological observations and behavioral evaluations, the aim of this study was to investigate the influence of transplanted olfactory ensheathing cells (OECs), irradiated by LPL, on functional repair of rats following transversal spinal cord injury. DESIGN, TIME AND SETTING: A randomized, controlled, animal experiment was performed at the animal experimental center in the First Affiliated Hospital of Xinjiang Medical University between January 2007 and February 2008. MATERIALS: A total of 52 Sprague Dawley rats were included in this experiment. Twelve rats were used to harvest OECs, some of which were irradiated by LPL on days 3, 5, and 7 in culture. The remaining 40 rats were used to establish T12 complete spinal cord transection injury. DMEM/F12 medium was purchased from Sigma, USA, Fluorogold was provided by Chemicon, USA, and the LY/JG650-D500-16 low-power laser was produced by Xi'an Lingyue Electromechanical Science And Technology Co., Ltd., China. METHODS: The successful rat models were randomly divided into three groups: OEC transplantation, LPL-irradiated OEC transplantation, and control. These animals were microinjected with OEC suspension, LPL-irradiated OEC suspension, and DMEM/F12 medium (10μL) respectively 4 weeks after spinal cord was completely transected at the T12 level. MAIN OUTCOME MEASURES: Spinal cord injury was observed using hematoxylin-eosin staining Expression of nerve growth factor receptor p75 and glial fibrillary acidic protein were determined using immunohistochemical staining. Regeneration of spinal nerve fibers in rats was assayed by Fluorogold retrograde labeling method. Basso, Beattie and Bresnahan (BBB) scores were used to evaluate motor functions of rat lower limbs. RESULTS: Structural disturbances were observed following spinal cord injury in each group, and a large amount of scar tissue covered the broken ends, accompanied by porosis and inflammatory cell infiltration. Following OEC transplantation, the distal end connected to the proximal end. nerve growth factor receptor p75 and glial fibrillary acidic protein immunohistochemistry revealed positive OECs in the cephalad and caudal area of rats that received LPL-irradiated OEC transplantation. In the OECs group, only glial fibrillary acidic protein staining was observed. No staining was found in the control group. Neural fibers labeled with Fluorogold extended across the lesion area and into the cephalad and caudal area in the OECs and LPL-irradiated OECs groups, but were not present in the control group. BBB scores revealed statistically significant differences among the three groups (P 〈 0.05): OECs irradiated by LPL group 〉 OECs group 〉 control group. CONCLUSION: Transplantation of OECs and LPL-irradiated OECs promoted functional repair in the injured spinal cord of rats, although LPL-irradiated OECs resulted in greater beneficial effects. 展开更多
关键词 olfactory ensheathing cells spinal cord injury cell transplantation low-power laser irradiationn
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A low-power high-throughput link splitting router for NoCs 被引量:2
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作者 Mohsen SANEEI Ali AFZALI-KUSHA Zainalabedin NAVABI 《Journal of Zhejiang University-Science A(Applied Physics & Engineering)》 SCIE EI CAS CSCD 2008年第12期1708-1714,共7页
In this paper, we propose a technique for lowering the latency of the communication in a NoC (network on chip). The technique, which can support two qualities of service (QoS), i.e., the guaranteed throughput (GT... In this paper, we propose a technique for lowering the latency of the communication in a NoC (network on chip). The technique, which can support two qualities of service (QoS), i.e., the guaranteed throughput (GT) and best effort (BE), is based on splitting a wider link into narrower links to increase throughput and decrease latency in the NoC. In addition, to ease the synchronization and reduce the crosstalk, we use the l-of-4 encoding for the smaller buses. The use of the encoding in the proposed NoC architecture considerably lowers the latency for both BE and GT packets. In addition, the bandwidth is increased while the power consumption of the links is reduced. 展开更多
关键词 low-power LATENCY Throughput Network on chip (NoC) Delay-insensitive ROUTER
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Low-power laser irradiation inhibits arecoline-induced fibrosis:an in vitro study 被引量:2
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作者 Mei-Chun Yeh Ker-Kong Chen +4 位作者 Min-Hsuan Chiang Chia-Hsin Chen Ping-Ho Chen Huey-Er Lee Yan-Hsiung Wang 《International Journal of Oral Science》 SCIE CAS CSCD 2017年第1期38-42,共5页
Oral submucous fibrosis (OSF) is a potentially malignant disorder that is characterized by a progressive fibrosis in the oral submucosa. Arecoline, an alkaloid compound of the areca nut, is reported to be a major ae... Oral submucous fibrosis (OSF) is a potentially malignant disorder that is characterized by a progressive fibrosis in the oral submucosa. Arecoline, an alkaloid compound of the areca nut, is reported to be a major aetiological factor in the development of OSF. Low-power laser irradiation (LPLI) has been reported to be beneficial in fibrosis prevention in different damaged organs. The aim of this study was to investigate the potential therapeutic effects of LPLI on arecoline-induced fibrosis. Arecoline- stimulated human gingival fibroblasts (HGFs) were treated with or without LPLI. The expression levels of the fibrotic marker genes alpha-smooth muscle actin (a-SMA) and connective tissue growth factor (CTGF/CCN2) were analysed by quantitative real- time reverse transcription polymerase chain reaction (RT-PCR) and western blots. In addition, the transcriptional activity of CCN2 was further determined by a reporter assay. The results indicated that arecoline increased the messenger RNA and protein expression of CCN2 and a-SMA in HGF. Interestingly, both LPLI and forskolin, an adenylyl cyclase activator, reduced the expression of arecoline-mediated fibrotic marker genes and inhibited the transcriptional activity of CCN2. Moreover, pretreatment with SQ22536, an adenylyl cyclase inhibitor, blocked LPLI's inhibition of the expression of arecoline-mediated fibrotic marker genes. Our data suggest that LPLI may inhibit the expression of arecoline-mediated fibrotic marker genes via the cAMP signalling pathway. 展开更多
关键词 adenylate cyclase alpha-smooth muscle actin connective tissue growth factor FIBROSIS low-power laser irradiation
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Design of Low-Power Data Logger of Deep Sea for Long-Term Field Observation 被引量:1
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作者 赵伟 陈鹰 +2 位作者 杨灿军 曹建伟 顾临怡 《China Ocean Engineering》 SCIE EI 2009年第1期133-144,共12页
This paper describes the implementation of a data logger for the real-time in-situ monitoring of hydrothermal systems. A compact mechanical structure ensures the security and reliability of data logger when used under... This paper describes the implementation of a data logger for the real-time in-situ monitoring of hydrothermal systems. A compact mechanical structure ensures the security and reliability of data logger when used under deep sea. The data logger is a battery powered instrument, which can connect chemical sensors (pH electrode, H2S electrode, H2 electrode) and temperature sensors. In order to achieve major energy savings, dynamic power management is implemented in hardware design and software design. The working current of the data logger in idle mode and active mode is 15 μA and 1.44 mA respectively, which greatly extends the working time of battery. The data logger has been successftdly tested in the first Sino-American Cooperative Deep Submergence Project from August 13 to September 3, 2005. 展开更多
关键词 data logger low-power design deep sea long-term monitoring
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An artificial synapse by superlattice-like phase-change material for low-power brain-inspired computing 被引量:1
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作者 Qing Hu Boyi Dong +5 位作者 Lun Wang Enming Huang Hao Tong Yuhui He Ming Xu Xiangshui Miao 《Chinese Physics B》 SCIE EI CAS CSCD 2020年第7期49-54,共6页
Phase-change material(PCM)is generating widespread interest as a new candidate for artificial synapses in bioinspired computer systems.However,the amorphization process of PCM devices tends to be abrupt,unlike continu... Phase-change material(PCM)is generating widespread interest as a new candidate for artificial synapses in bioinspired computer systems.However,the amorphization process of PCM devices tends to be abrupt,unlike continuous synaptic depression.The relatively large power consumption and poor analog behavior of PCM devices greatly limit their applications.Here,we fabricate a GeTe/Sb2Te3 superlattice-like PCM device which allows a progressive RESET process.Our devices feature low-power consumption operation and potential high-density integration,which can effectively simulate biological synaptic characteristics.The programming energy can be further reduced by properly selecting the resistance range and operating method.The fabricated devices are implemented in both artificial neural networks(ANN)and convolutional neural network(CNN)simulations,demonstrating high accuracy in brain-like pattern recognition. 展开更多
关键词 superlattice-like phase-change material artificial synapse low-power consumption
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