BACKGROUND Reduced level of physical activity,high-fat diet and skeletal muscle atrophy are key factors that are likely to contribute to deleterious changes in body composition and metabolic following spinal cord inju...BACKGROUND Reduced level of physical activity,high-fat diet and skeletal muscle atrophy are key factors that are likely to contribute to deleterious changes in body composition and metabolic following spinal cord injury (SCI).Reduced caloric intake with lowering percentage macronutrients of fat and increasing protein intake may likely to improve body composition parameters and decrease ectopic adiposity after SCI.AIM To highlight the effects of dietary manipulation and testosterone replacement therapy (TRT) on body composition after SCI METHODS A 31-year-old male with T5 SCI was administered transdermal TRT daily for 16 wk.Caloric intake and percentage macronutrients were analyzed using dietary recalls.Magnetic resonance imaging and dual-energy x-ray absorptiometry were used to measure changes in body composition.RESULTS Caloric intake and fat percentage were reduced by 445 kcal/d and 6.5%,respectively.Total body weight decreased by 8%,body fat decreased by 29%,and lean mass increased by 7%.Thigh subcutaneous adipose tissue cross-sectional area was reduced by 31%.CONCLUSION Manipulation of caloric intake,fat percentage,and protein percentage may have influenced body composition after SCI.展开更多
The relationship between primary intestinal lymphangiectasia(PIL) and liver fibrosis is an emerging topic with many obscure aspects due to the rarity of the disorder.A recent paper reported that a six-month lowfat die...The relationship between primary intestinal lymphangiectasia(PIL) and liver fibrosis is an emerging topic with many obscure aspects due to the rarity of the disorder.A recent paper reported that a six-month lowfat diet improved liver fibrosis.We report the case of a 17-year-old girl affected by PIL whose hepatic fibrosis progressively worsened within one year,despite dietetic support.This and the previous case report describe extraordinary events,which do not allow clear-cut clinical aspects to be established.Nevertheless,both cases suggest that in patients with PIL,it is necessary to closely monitor liver morphology with in-depth investigations including not only ultrasonography,but also elastography.展开更多
This study was conducted to evaluate the influence of dietary lysophospholipids combined with 1%dietary fish oil reduction on the growth performance and hepatic lipid metabolism of largemouth bass(Micropterus salmoide...This study was conducted to evaluate the influence of dietary lysophospholipids combined with 1%dietary fish oil reduction on the growth performance and hepatic lipid metabolism of largemouth bass(Micropterus salmoides).Five isonitrogenous feeds were prepared with lysophospholipids at 0%(fish oil group,FO),0.05%(L-0.05),0.1%(L-0.1),0.15%(L-0.15)and 0.2%(L-0.2),respectively.The dietary lipid was 11%in the FO diet and 10%in the other diets.Largemouth bass were fed for 68 d(initial body weight=6.04±0.01 g)with 4 replicates per group and 30 fish per replicate.The results showed that the fish fed diet containing 0.1%lysophospholipids had higher digestive enzyme activity and obtained better growth performance compared to the fish fed FO diet(P<0.05).The feed conversion rate in the L-0.1 group was significantly lower than that in the other groups.Serum total protein and triglyceride contents in L-0.1 group were significantly higher than those in other groups(P<0.05)and the contents of total cholesterol and low-density lipoprotein cholesterol in L-0.1 group were significantly lower than those in FO group(P<0.05).The activity and genes expression of hepatic glucolipid metabolizing enzymes in L-0.15 group were significantly increased compared to those in FO group(P<0.05).Reducing 1%fish oil along with 0.1%lysophospholipids added to the feed could improve the digestion and absorption of nutrients,enhance the activity of liver glycolipid metabolizing enzymes,and thus effectively promote the growth of largemouth bass.展开更多
基金Supported by Department of Veteran Affairs,Veteran Health Administration,Rehabilitation Research and Development Service,No.1IK2RX000732-01A1
文摘BACKGROUND Reduced level of physical activity,high-fat diet and skeletal muscle atrophy are key factors that are likely to contribute to deleterious changes in body composition and metabolic following spinal cord injury (SCI).Reduced caloric intake with lowering percentage macronutrients of fat and increasing protein intake may likely to improve body composition parameters and decrease ectopic adiposity after SCI.AIM To highlight the effects of dietary manipulation and testosterone replacement therapy (TRT) on body composition after SCI METHODS A 31-year-old male with T5 SCI was administered transdermal TRT daily for 16 wk.Caloric intake and percentage macronutrients were analyzed using dietary recalls.Magnetic resonance imaging and dual-energy x-ray absorptiometry were used to measure changes in body composition.RESULTS Caloric intake and fat percentage were reduced by 445 kcal/d and 6.5%,respectively.Total body weight decreased by 8%,body fat decreased by 29%,and lean mass increased by 7%.Thigh subcutaneous adipose tissue cross-sectional area was reduced by 31%.CONCLUSION Manipulation of caloric intake,fat percentage,and protein percentage may have influenced body composition after SCI.
文摘The relationship between primary intestinal lymphangiectasia(PIL) and liver fibrosis is an emerging topic with many obscure aspects due to the rarity of the disorder.A recent paper reported that a six-month lowfat diet improved liver fibrosis.We report the case of a 17-year-old girl affected by PIL whose hepatic fibrosis progressively worsened within one year,despite dietetic support.This and the previous case report describe extraordinary events,which do not allow clear-cut clinical aspects to be established.Nevertheless,both cases suggest that in patients with PIL,it is necessary to closely monitor liver morphology with in-depth investigations including not only ultrasonography,but also elastography.
基金supported by Guangdong Provincial Special Fund for Modern Agriculture Industry Technology Innovation Team(2023KJ150)Special Project on Key Fields of Guangdong Universities(Rural Revitalization)(2020ZDZX1034).
文摘This study was conducted to evaluate the influence of dietary lysophospholipids combined with 1%dietary fish oil reduction on the growth performance and hepatic lipid metabolism of largemouth bass(Micropterus salmoides).Five isonitrogenous feeds were prepared with lysophospholipids at 0%(fish oil group,FO),0.05%(L-0.05),0.1%(L-0.1),0.15%(L-0.15)and 0.2%(L-0.2),respectively.The dietary lipid was 11%in the FO diet and 10%in the other diets.Largemouth bass were fed for 68 d(initial body weight=6.04±0.01 g)with 4 replicates per group and 30 fish per replicate.The results showed that the fish fed diet containing 0.1%lysophospholipids had higher digestive enzyme activity and obtained better growth performance compared to the fish fed FO diet(P<0.05).The feed conversion rate in the L-0.1 group was significantly lower than that in the other groups.Serum total protein and triglyceride contents in L-0.1 group were significantly higher than those in other groups(P<0.05)and the contents of total cholesterol and low-density lipoprotein cholesterol in L-0.1 group were significantly lower than those in FO group(P<0.05).The activity and genes expression of hepatic glucolipid metabolizing enzymes in L-0.15 group were significantly increased compared to those in FO group(P<0.05).Reducing 1%fish oil along with 0.1%lysophospholipids added to the feed could improve the digestion and absorption of nutrients,enhance the activity of liver glycolipid metabolizing enzymes,and thus effectively promote the growth of largemouth bass.