The present study aimed to compare the complications and clinical outcomes of serial lumbar puncture（LP） and lumbar cerebrospinal fluid（CSF） drainage（LD） of patients with aneurysmal subarachnoid hemorrhage and p...The present study aimed to compare the complications and clinical outcomes of serial lumbar puncture（LP） and lumbar cerebrospinal fluid（CSF） drainage（LD） of patients with aneurysmal subarachnoid hemorrhage and provide more evidence to guide clinical management.In this retrospective study,41 and 39 aneurysmal subarachnoid hemorrhage patients were enrolled in the LP and LD group,respectively.Clinical outcomes,including CSF infection,intracerebral hemorrhage,vasospasm,hydrocephalus,death,length of stay,duration of drainage and the Glasgow Outcome Scale score were compared between the two groups.By comparing with the LP group,the LD group showed a significantly higher rate of CSF infection（P= 0.029） and shorter duration of drainage（P〈 0.001）.Both groups displayed similar rates of vasospasm,hydrocephalus,intracerebral hemorrhage,the Glasgow Outcome Scale score one month after endovascular coiling and length of stay（P〉 0.05,respectively）.In conclusion,both LD and serial LP are effective methods in the treatment of aneurysmal subarachnoid hemorrhage; besides,serial LP can reduce the incidence of CSF infection in draining hemorrhagic CSF in aneurysmal subarachnoid hemorrhage after endovascular coiling.展开更多
Objective To explore the therapeutic effect of preoperative external lumbar drainage in Hunt and Hess grade Ⅰ～Ⅲ patients with subarachnoid hemorrhage (SAH) undergoing early surgery for intracranial aneurysms. Metho...Objective To explore the therapeutic effect of preoperative external lumbar drainage in Hunt and Hess grade Ⅰ～Ⅲ patients with subarachnoid hemorrhage (SAH) undergoing early surgery for intracranial aneurysms. Methods 101 cases of gradeⅠ～Ⅲ patients according to the classification of Hunt and Hess展开更多
目的分析持续腰大池引流术用于动脉瘤破裂后引起蛛网膜下腔出血中的治疗效果。方法非随机选取2020年1月—2023年6月兴义市人民医院神经外科收治的100例动脉瘤破裂后引起蛛网膜下腔出血的患者为研究对象。按治疗方式不同分为两组,每组50...目的分析持续腰大池引流术用于动脉瘤破裂后引起蛛网膜下腔出血中的治疗效果。方法非随机选取2020年1月—2023年6月兴义市人民医院神经外科收治的100例动脉瘤破裂后引起蛛网膜下腔出血的患者为研究对象。按治疗方式不同分为两组,每组50例。对照组行常规腰椎穿刺引流术,研究组行持续腰大池引流术治疗。比较两组治疗效果、脑血管痉挛、颅内感染情况、格拉斯哥昏迷评分(Glasgow Coma Scale,GCS)、改良Rankin量表评分。结果研究组总有效率为96.00%(48/50),高于对照组的80.00%(40/50),差异有统计学意义(χ^(2)=4.640,P<0.05)。研究组术后脑血管痉挛、颅内感染发生率低于对照组,差异有统计学意义(P均<0.05)。术后,研究组GCS评分高于对照组,改良Rankin量表评分低于对照组,差异有统计学意义(P均<0.05)。结论持续腰大池引流术治疗方案可以提升整体治疗效果,减少颅内感染及脑血管痉挛情况,缓解患者病情。展开更多
Despite the increasing number of reports of patients with perimesencephalic subarachnoid hemorrhage (PMSAH), a minor or atypical PMSAH on CT changes has not been reported. We present the first described case of a mino...Despite the increasing number of reports of patients with perimesencephalic subarachnoid hemorrhage (PMSAH), a minor or atypical PMSAH on CT changes has not been reported. We present the first described case of a minor subarachnoid hemorrhage located in the right perimesencephalic cistern on CT 4 h after headache onset. Twenty-six hours after headache on-set, another CT of the head showed that blood dis-persion. On the third day in hospital, examination of cerebrospinal fluid revealed xanthochromia. Minor PMSAH is rare type of SAH, and can been missed if there is a delay in CT imaging of the head. Any pa-tient with a suspected minor PMSAH or equivocal results on CT should undergo routine lumbar punc-ture.展开更多
目的探讨腰大池引流术在脊柱肿瘤硬膜囊缺损合并难治性脑脊液漏患者中的应用价值。方法回顾性分析本院2005年1月~2012年12月收治的84例脊柱肿瘤硬膜缺损合并难治性脑脊液漏的患者,行持续性腰大池引流术,观察患者术后即刻,术后1周,术后3...目的探讨腰大池引流术在脊柱肿瘤硬膜囊缺损合并难治性脑脊液漏患者中的应用价值。方法回顾性分析本院2005年1月~2012年12月收治的84例脊柱肿瘤硬膜缺损合并难治性脑脊液漏的患者,行持续性腰大池引流术,观察患者术后即刻,术后1周,术后3周时体温变化;术前、术后1周,术后3周时白细胞、血沉,C-反应蛋白的变化。术后3 d、1周,3周内脑脊液量变化的情况。结果实施腰大池引流术后,患者体温、白细胞、血沉、C-反应蛋白出现先升高,随着治疗的进行而逐渐下降恢复为正常水平。放置腰大池引流前,患者脑脊液引流量为135~670 m L/d,平均356 m L/d;术后3周时,多数患者引流量已经降至正常。腰大池引流的放置时间13~25 d,平均16.3 d。腰大池引流中发生引流过度4例、引流不畅3例、引流管滑脱1例,经过调整引流速度,冲洗疏通管腔,适时缝闭皮缘达到满意效果。至末次随访时,原伤口中1例出现皮肤发红,1例发生局部血肿,1例伤口愈合不佳,1例伤口渗液,其余患者均取得了较良好的引流效果,并实现顺利拔除原伤口引流管。结论脊柱肿瘤中多数硬膜囊缺损无法完全缝合修补。对伴有难治性脑脊液漏患者采取降低局部脑脊液压力的持续性腰大池引流术,对促进硬膜的修复和预防并发症的发生有显著的效果。展开更多
文摘The present study aimed to compare the complications and clinical outcomes of serial lumbar puncture（LP） and lumbar cerebrospinal fluid（CSF） drainage（LD） of patients with aneurysmal subarachnoid hemorrhage and provide more evidence to guide clinical management.In this retrospective study,41 and 39 aneurysmal subarachnoid hemorrhage patients were enrolled in the LP and LD group,respectively.Clinical outcomes,including CSF infection,intracerebral hemorrhage,vasospasm,hydrocephalus,death,length of stay,duration of drainage and the Glasgow Outcome Scale score were compared between the two groups.By comparing with the LP group,the LD group showed a significantly higher rate of CSF infection（P= 0.029） and shorter duration of drainage（P〈 0.001）.Both groups displayed similar rates of vasospasm,hydrocephalus,intracerebral hemorrhage,the Glasgow Outcome Scale score one month after endovascular coiling and length of stay（P〉 0.05,respectively）.In conclusion,both LD and serial LP are effective methods in the treatment of aneurysmal subarachnoid hemorrhage; besides,serial LP can reduce the incidence of CSF infection in draining hemorrhagic CSF in aneurysmal subarachnoid hemorrhage after endovascular coiling.
文摘Objective To explore the therapeutic effect of preoperative external lumbar drainage in Hunt and Hess grade Ⅰ～Ⅲ patients with subarachnoid hemorrhage (SAH) undergoing early surgery for intracranial aneurysms. Methods 101 cases of gradeⅠ～Ⅲ patients according to the classification of Hunt and Hess
文摘目的分析持续腰大池引流术用于动脉瘤破裂后引起蛛网膜下腔出血中的治疗效果。方法非随机选取2020年1月—2023年6月兴义市人民医院神经外科收治的100例动脉瘤破裂后引起蛛网膜下腔出血的患者为研究对象。按治疗方式不同分为两组,每组50例。对照组行常规腰椎穿刺引流术,研究组行持续腰大池引流术治疗。比较两组治疗效果、脑血管痉挛、颅内感染情况、格拉斯哥昏迷评分(Glasgow Coma Scale,GCS)、改良Rankin量表评分。结果研究组总有效率为96.00%(48/50),高于对照组的80.00%(40/50),差异有统计学意义(χ^(2)=4.640,P<0.05)。研究组术后脑血管痉挛、颅内感染发生率低于对照组,差异有统计学意义(P均<0.05)。术后,研究组GCS评分高于对照组,改良Rankin量表评分低于对照组,差异有统计学意义(P均<0.05)。结论持续腰大池引流术治疗方案可以提升整体治疗效果,减少颅内感染及脑血管痉挛情况,缓解患者病情。
文摘Despite the increasing number of reports of patients with perimesencephalic subarachnoid hemorrhage (PMSAH), a minor or atypical PMSAH on CT changes has not been reported. We present the first described case of a minor subarachnoid hemorrhage located in the right perimesencephalic cistern on CT 4 h after headache onset. Twenty-six hours after headache on-set, another CT of the head showed that blood dis-persion. On the third day in hospital, examination of cerebrospinal fluid revealed xanthochromia. Minor PMSAH is rare type of SAH, and can been missed if there is a delay in CT imaging of the head. Any pa-tient with a suspected minor PMSAH or equivocal results on CT should undergo routine lumbar punc-ture.
文摘目的探讨腰大池引流术在脊柱肿瘤硬膜囊缺损合并难治性脑脊液漏患者中的应用价值。方法回顾性分析本院2005年1月~2012年12月收治的84例脊柱肿瘤硬膜缺损合并难治性脑脊液漏的患者,行持续性腰大池引流术,观察患者术后即刻,术后1周,术后3周时体温变化;术前、术后1周,术后3周时白细胞、血沉,C-反应蛋白的变化。术后3 d、1周,3周内脑脊液量变化的情况。结果实施腰大池引流术后,患者体温、白细胞、血沉、C-反应蛋白出现先升高,随着治疗的进行而逐渐下降恢复为正常水平。放置腰大池引流前,患者脑脊液引流量为135~670 m L/d,平均356 m L/d;术后3周时,多数患者引流量已经降至正常。腰大池引流的放置时间13~25 d,平均16.3 d。腰大池引流中发生引流过度4例、引流不畅3例、引流管滑脱1例,经过调整引流速度,冲洗疏通管腔,适时缝闭皮缘达到满意效果。至末次随访时,原伤口中1例出现皮肤发红,1例发生局部血肿,1例伤口愈合不佳,1例伤口渗液,其余患者均取得了较良好的引流效果,并实现顺利拔除原伤口引流管。结论脊柱肿瘤中多数硬膜囊缺损无法完全缝合修补。对伴有难治性脑脊液漏患者采取降低局部脑脊液压力的持续性腰大池引流术,对促进硬膜的修复和预防并发症的发生有显著的效果。
