Objective To evaluate the complication rate of CT-guided percutaneous lung biopsy and determine the risk factors for complications. MethodsA retrospective investigation of CT-guided percutaneous lung biopsy carried ou...Objective To evaluate the complication rate of CT-guided percutaneous lung biopsy and determine the risk factors for complications. MethodsA retrospective investigation of CT-guided percutaneous lung biopsy carried out between 2002 and 2009 was performed. The risk factors for complications were determined by multivariate analysis of variables related to patient demographics, lung lesions, and biopsy procedures. ResultsA total of 281 biopsy procedures were enrolled. The total complication rate was 55.9% with pneumothorax 32.4% (91/281) and bleeding 34.5% (97/281). The risk factors affecting pneumothorax rate were lesion location, lesion depth, and time of pleural pierce; and the risk factors affecting bleeding complications were lesion depth, lesion size, and age. Predictive models for pneumothorax and bleeding were established by logistic regression. The pneumothorax model had a sensitivity of 80.0% with a specificity of 62.4%,and the bleeding model had a sensitivity of 67.4% with a specificity of 88.8%. ConclusionLesion location, lesion depth, and number of pleural passes were independent risk factors for pneumothorax. Lesion size, lesion depth, and age were independent risk factor for bleeding. The predictive models for pneumothorax and bleeding will helpfully reduce the complication of CT-guided lung biopsy.展开更多
目的:探讨初次经皮肺穿刺活检过程中因气胸而活检失败,使用单腔深静脉管抽气后再行活检的安全性和可行性。方法:2017年8月至2021年8月452例患者行CT引导下肺穿刺活检,其中12例因出现气胸而活检失败,使用单腔深静脉管置入抽气并再次行肺...目的:探讨初次经皮肺穿刺活检过程中因气胸而活检失败,使用单腔深静脉管抽气后再行活检的安全性和可行性。方法:2017年8月至2021年8月452例患者行CT引导下肺穿刺活检,其中12例因出现气胸而活检失败,使用单腔深静脉管置入抽气并再次行肺活检。回顾性分析12例患者的病例资料,记录肺内病灶的大小、距离胸膜的距离、病灶在肺叶的位置、有无肺气肿、有无成功获得组织、有无明确的病理结果、有无肺内出血等并发症。结果:12例肺病灶直径为1.5~3.5 cm, 3例距离胸膜较近,平均距离为1.2 cm, 9例距离胸膜较远,平均距离为5.5 cm;8例病灶位于肺下叶,2例位于右肺中叶,2例位于右肺上叶,4例患者有肺气肿;12例患者再次活检后均成功取到组织并有明确的病理结果。活检完成后CT复查有4例出现少量渗出性改变,其中2例少量咯血,均经保守治疗后好转。1例合并肺气肿患者术后1 h出现大量气胸,行胸腔闭式引流后明显缓解。所有患者均未出现胸腔积液或其他严重并发症。结论:初次经皮肺穿刺活检过程中因气胸而活检失败,使用单腔深静脉管抽气后再次行肺活检安全、有效,值得临床推广应用。展开更多
Dr.Takao Hiraki is a scientist carrying out interventional radiology research in the Department of Radiology at Okayama University Medical School,Japan.He has conducted animal and human clinical studies on interventio...Dr.Takao Hiraki is a scientist carrying out interventional radiology research in the Department of Radiology at Okayama University Medical School,Japan.He has conducted animal and human clinical studies on interventional radiology for various conditions.For example,he clarified the hepatic hemodynamic changes caused by hepatic venous occlusion.He also developed new devices,such as hydrogel coils for the occlusion of the aneurismal sac after an endovascular stent-graft of an aortic aneurysm to prevent endoleakage and small intestinal submucosa-covered stents for transjugular intrahepatic portosystemic shunts.Further,he performed a number of studies on the radiofrequency ablation of lung cancer,mediastinal lymph node metastasis,and computed tomography-fluoroscopy-guided lung biopsies.He intends to continue to dedicate his academic career to expand the role of interventional radiology in clinical medicine.展开更多
文摘Objective To evaluate the complication rate of CT-guided percutaneous lung biopsy and determine the risk factors for complications. MethodsA retrospective investigation of CT-guided percutaneous lung biopsy carried out between 2002 and 2009 was performed. The risk factors for complications were determined by multivariate analysis of variables related to patient demographics, lung lesions, and biopsy procedures. ResultsA total of 281 biopsy procedures were enrolled. The total complication rate was 55.9% with pneumothorax 32.4% (91/281) and bleeding 34.5% (97/281). The risk factors affecting pneumothorax rate were lesion location, lesion depth, and time of pleural pierce; and the risk factors affecting bleeding complications were lesion depth, lesion size, and age. Predictive models for pneumothorax and bleeding were established by logistic regression. The pneumothorax model had a sensitivity of 80.0% with a specificity of 62.4%,and the bleeding model had a sensitivity of 67.4% with a specificity of 88.8%. ConclusionLesion location, lesion depth, and number of pleural passes were independent risk factors for pneumothorax. Lesion size, lesion depth, and age were independent risk factor for bleeding. The predictive models for pneumothorax and bleeding will helpfully reduce the complication of CT-guided lung biopsy.
文摘目的:探讨初次经皮肺穿刺活检过程中因气胸而活检失败,使用单腔深静脉管抽气后再行活检的安全性和可行性。方法:2017年8月至2021年8月452例患者行CT引导下肺穿刺活检,其中12例因出现气胸而活检失败,使用单腔深静脉管置入抽气并再次行肺活检。回顾性分析12例患者的病例资料,记录肺内病灶的大小、距离胸膜的距离、病灶在肺叶的位置、有无肺气肿、有无成功获得组织、有无明确的病理结果、有无肺内出血等并发症。结果:12例肺病灶直径为1.5~3.5 cm, 3例距离胸膜较近,平均距离为1.2 cm, 9例距离胸膜较远,平均距离为5.5 cm;8例病灶位于肺下叶,2例位于右肺中叶,2例位于右肺上叶,4例患者有肺气肿;12例患者再次活检后均成功取到组织并有明确的病理结果。活检完成后CT复查有4例出现少量渗出性改变,其中2例少量咯血,均经保守治疗后好转。1例合并肺气肿患者术后1 h出现大量气胸,行胸腔闭式引流后明显缓解。所有患者均未出现胸腔积液或其他严重并发症。结论:初次经皮肺穿刺活检过程中因气胸而活检失败,使用单腔深静脉管抽气后再次行肺活检安全、有效,值得临床推广应用。
文摘目的 探讨CT引导下经皮肺穿刺活检并发症的影响因素及处理方法。方法 回顾性分析253例CT引导下经皮肺穿刺活检并发症的影响因素及相应处理方法。结果 253例中,77例(77/253,30.43%)肺出血,包括4例(4/77,5.19%)大量出血,有无肺出血患者的病变位置、病灶大小、穿刺深度、取材数量差异均有统计学意义( P 均<0.05);55例(55/253,21.74%)发生气胸,其中5例接受胸腔闭式引流,有无气胸患者的病变位置、病灶大小、取材数量差异均有统计学意义( P 均<0.05)。结论 CT引导下经皮肺穿刺活检后肺出血的影响因素为病变位置、病灶大小、穿刺深度及取材数量,气胸的影响因素为病变位置、大小及取材数量,均可预防、可处理。
文摘Dr.Takao Hiraki is a scientist carrying out interventional radiology research in the Department of Radiology at Okayama University Medical School,Japan.He has conducted animal and human clinical studies on interventional radiology for various conditions.For example,he clarified the hepatic hemodynamic changes caused by hepatic venous occlusion.He also developed new devices,such as hydrogel coils for the occlusion of the aneurismal sac after an endovascular stent-graft of an aortic aneurysm to prevent endoleakage and small intestinal submucosa-covered stents for transjugular intrahepatic portosystemic shunts.Further,he performed a number of studies on the radiofrequency ablation of lung cancer,mediastinal lymph node metastasis,and computed tomography-fluoroscopy-guided lung biopsies.He intends to continue to dedicate his academic career to expand the role of interventional radiology in clinical medicine.
