The isoflavone compound Calycosin-7-O-β-D-glucoside (CG) is an active monomer component extracted from the dry roots of the leguminous plant Astragalus mongolicus and Astragalus. It is also one of the main active ing...The isoflavone compound Calycosin-7-O-β-D-glucoside (CG) is an active monomer component extracted from the dry roots of the leguminous plant Astragalus mongolicus and Astragalus. It is also one of the main active ingredients in the Astragalus that is a commonly used traditional herb. CG has obvious effects of anti-oxidation, anti-virus, inhibition of melanin formation, and immunosuppression. With the advancement of modern technology, it has become a pivotal subject that the adjuvant therapy or even substitute for the synthetic drug of monomer of Chinese herb in medical field. In recent years, with the deepening of research on the mechanism of action of CG, which has been found that its pharmacological effects are very extensive, such as the anti-tumor effect and the effect on cerebrovascular diseases of CG. This review summarizes the pharmacological effects and the latest research progress of CG.展开更多
A new flavone glucoside,selagin-7-O-（6″-O-acetyl-）-β-D-glycoside,has been isolated from Cancrinia discoidea（Ledeb.） Poljak.Its structure was identified by spectroscopic methods,2D NMR and MS.Compounds exhibited ...A new flavone glucoside,selagin-7-O-（6″-O-acetyl-）-β-D-glycoside,has been isolated from Cancrinia discoidea（Ledeb.） Poljak.Its structure was identified by spectroscopic methods,2D NMR and MS.Compounds exhibited activity of anti-inflammatory in vitro.展开更多
基金General Project Foundation of Guangdong Traditional Chinese Medicine (20191192)
文摘The isoflavone compound Calycosin-7-O-β-D-glucoside (CG) is an active monomer component extracted from the dry roots of the leguminous plant Astragalus mongolicus and Astragalus. It is also one of the main active ingredients in the Astragalus that is a commonly used traditional herb. CG has obvious effects of anti-oxidation, anti-virus, inhibition of melanin formation, and immunosuppression. With the advancement of modern technology, it has become a pivotal subject that the adjuvant therapy or even substitute for the synthetic drug of monomer of Chinese herb in medical field. In recent years, with the deepening of research on the mechanism of action of CG, which has been found that its pharmacological effects are very extensive, such as the anti-tumor effect and the effect on cerebrovascular diseases of CG. This review summarizes the pharmacological effects and the latest research progress of CG.
基金supported by the National Natural Science Foundation of China(No.20676041)by the China Postdoctoral Science Foundation(No.2004036506)
文摘A new flavone glucoside,selagin-7-O-（6″-O-acetyl-）-β-D-glycoside,has been isolated from Cancrinia discoidea（Ledeb.） Poljak.Its structure was identified by spectroscopic methods,2D NMR and MS.Compounds exhibited activity of anti-inflammatory in vitro.
