There has been an increasing prevalence of lymphogranuloma venereum(LGV) or Chlamydia trachomatis(C.trachomatis) cases among the men who have sex with men(MSM) population,particularly in Europe and North America.These...There has been an increasing prevalence of lymphogranuloma venereum(LGV) or Chlamydia trachomatis(C.trachomatis) cases among the men who have sex with men(MSM) population,particularly in Europe and North America.These cases may present with an incomplete or undisclosed history and proctosigmoiditis without characteristic adenopathy syndrome.During the initial evaluation and colonoscopy,there is a strong clinical and endoscopic suspicion of inflammatory bowel disease(IBD) by virtue of presentation and endoscopic and histological findings.The diagnosis of IBD is subsequently modified to LGV proctosigmoiditis when one or more of the following transpire:(1) there is failure of response to IBD therapy;(2) additional components of history(MSM/travel) may be identified;(3) return of initially performed Chlamydia antibody test is positive;and(4) response to antibiotics effective against Chlamydia.We describe three such cases initially suspectedto be an inflammatory bowel disease and subsequently identified as C.trachomatis proctosigmoiditis.展开更多
Lymphogranuloma venereum （LGV） is a systemic sexually transmitted disease caused by Chlamydia trachomatis （C. trachomatis） L1, L2 and L3, the organism gains entrance through skin breaks and abrasions and travels v...Lymphogranuloma venereum （LGV） is a systemic sexually transmitted disease caused by Chlamydia trachomatis （C. trachomatis） L1, L2 and L3, the organism gains entrance through skin breaks and abrasions and travels via the lymphatics to multiply within mononuclear phagocytes in regional lymph nodes, The clinical presentation of LGV depends on the sex of the patient, mode of sexual contact （e.g. vaginal or anal sex） and the stage of the disease. LGV is diagnosed in men up to 6 times more frequently than in women, but the infected women are more likely developed to late stage. LGV is rare in China, however the incidence was increasing in recent years. In this paper we diagnosed a case of LGV, and confirmed this case was caused by L3 serovar of C. trachomatis by using genotype test.展开更多
文摘There has been an increasing prevalence of lymphogranuloma venereum(LGV) or Chlamydia trachomatis(C.trachomatis) cases among the men who have sex with men(MSM) population,particularly in Europe and North America.These cases may present with an incomplete or undisclosed history and proctosigmoiditis without characteristic adenopathy syndrome.During the initial evaluation and colonoscopy,there is a strong clinical and endoscopic suspicion of inflammatory bowel disease(IBD) by virtue of presentation and endoscopic and histological findings.The diagnosis of IBD is subsequently modified to LGV proctosigmoiditis when one or more of the following transpire:(1) there is failure of response to IBD therapy;(2) additional components of history(MSM/travel) may be identified;(3) return of initially performed Chlamydia antibody test is positive;and(4) response to antibiotics effective against Chlamydia.We describe three such cases initially suspectedto be an inflammatory bowel disease and subsequently identified as C.trachomatis proctosigmoiditis.
文摘Lymphogranuloma venereum （LGV） is a systemic sexually transmitted disease caused by Chlamydia trachomatis （C. trachomatis） L1, L2 and L3, the organism gains entrance through skin breaks and abrasions and travels via the lymphatics to multiply within mononuclear phagocytes in regional lymph nodes, The clinical presentation of LGV depends on the sex of the patient, mode of sexual contact （e.g. vaginal or anal sex） and the stage of the disease. LGV is diagnosed in men up to 6 times more frequently than in women, but the infected women are more likely developed to late stage. LGV is rare in China, however the incidence was increasing in recent years. In this paper we diagnosed a case of LGV, and confirmed this case was caused by L3 serovar of C. trachomatis by using genotype test.
