Very little is known about visual functional recovery following long-term naltrexone administration in opioid-dependent patients. In the present study, a portable event-related potential （ERP） working system was uti...Very little is known about visual functional recovery following long-term naltrexone administration in opioid-dependent patients. In the present study, a portable event-related potential （ERP） working system was utilized to collect and record ERP in opioid-dependent patients and normal controls in visual half-field testing. In addition, the influence of long-term sustained naltrexone release on the visual nervous system was observed in opioid-dependent patients. Results revealed a significant main group effect in reaction time to visual signal stimulations. The reaction time of normal controls was shortest, but longest in opioid-dependent patients. The reaction time of long-term sustained naltrexone release group and compulsory detoxification group was similar to normal controls. A significant main group effect was also observed in P100 latency, and P100 latency in normal controls and the compulsory detoxification group was significantly decreased compared with the opioid-dependent patients. P100 amplitude at the Oz-electrode resulted in a significant main group effect. In particular, normal controls exhibited significant differences compared with long-term sustained release naltrexone and compulsory detoxification groups. These findings demonstrated that long-term sustained naltrexone release effectively ameliorated optic center function and improved visual sensitivity and reactions in opioid-dependent patients.展开更多
With the rapid development of white LEDs,the research of new and efficient white light emitting materials has attracted increasing attention.Zero dimensional(0D)organic–inorganic hybrid metal halide perovskites with ...With the rapid development of white LEDs,the research of new and efficient white light emitting materials has attracted increasing attention.Zero dimensional(0D)organic–inorganic hybrid metal halide perovskites with superior luminescent property are promising candidates for LED application,due to their abundant and tailorable structure.Herein,[(CH_(3))_(3)S]_(2)SnCl_(6)・H_(2)O is synthesized as a host for dopant ions Bi^(3+)and Sb^(3+).The Sb^(3+)doped,or Bi^(3+)/Sb^(3+)co-doped,[(CH_(3))3S]_(2)SnCl_(6)・H_(2)O has a tunable optical emission spectrum by means of varying dopant ratio and excitation wavelength.As a result,we can achieve single-phase materials suitable for emission ranging from cold white light to warm white light.The intrinsic mechanism is examined in this work,to clarify the dopant effect on the optical properties.The high stability of title crystalline material,against water,oxygen and heat,makes it promising for further application.展开更多
The sensitivity of the D^0-D^-0 mixing parameters x and y is estimated in the wrong-sign decay D^0→K^＋π^-π^0 by time-dependent amplitude analysis. The resolution of the D^0 lifetime is essential in time-dependent ...The sensitivity of the D^0-D^-0 mixing parameters x and y is estimated in the wrong-sign decay D^0→K^＋π^-π^0 by time-dependent amplitude analysis. The resolution of the D^0 lifetime is essential in time-dependent Dalitz analyses. The Belle II detector, which aims to collect a total integrated luminosity of 50 ab^-1 of data, has σ = 140 fs in Monte Carlo studies, a factor of two improvement over that of Belle and Ba Bar, so the produced Dalitz signal Monte Carlo samples are smeared with this resolution. Then a time-dependent Dalitz plot fitting is performed on these smeared samples, and the sensitivity of D^0-D^-0 mixing parameters are σx = 0.057% and σy = 0.049%. These are about an order of magnitude improvement on current experimental results, without considering background effects.展开更多
To improve the yield strength of metallic materials at low temperatures,a strategy of combining the calculation of phase diagrams(CALPHAD)technique with the overall valence electron concentration(OVEC)principle is app...To improve the yield strength of metallic materials at low temperatures,a strategy of combining the calculation of phase diagrams(CALPHAD)technique with the overall valence electron concentration(OVEC)principle is applied,and a Ni_(2)CoCrNb_(0.2)medium-entropy alloy(MEA)with D022 superlattice(noted as theγ″phase)is designed.Bulk MEA samples without defects were successfully fabricated using laser additive manufacturing(AM),followed by solution treatment at 1200℃for 1 h and then aging at 650℃for 120 h.The nanoscaleγ″phase precipitated.The tensile results indicated that the MEA had superior yield strengths of∼1180 MPa and∼1320 MPa and tensile strengths of∼1335 MPa and∼1552 MPa at 293 K and 77 K,respectively.The yield strength obtained was superior to that of currently reported medium/high-entropy alloys and typical advanced cryogenic steel.The mechanical properties of the Ni_(2)CoCrNb_(0.2)MEA demonstrated a strong temperature dependence,and the increased yield strength was mainly attributed to the increase in lattice friction stress at low temperatures.This research provides a new strategy for producing materials with ultrastrong cryogenic yield strengths by AM.展开更多
The system which consists of a reliable machine, an unreliable machine and a storage buffer with infinite many workpieces has been studied. The existence of a unique positive time-dependent solution of the model corre...The system which consists of a reliable machine, an unreliable machine and a storage buffer with infinite many workpieces has been studied. The existence of a unique positive time-dependent solution of the model corresponding to the system has been obtained by using C 0-semigroup theory of linear operators in functional analysis.展开更多
基金the Natural Science Foundation of Guangdong Province,No. 06027973the Science and Technology Development Program of Guangdong Province,No. 2004B3600105the Medical Science Foundation Program of Guangdong Province,No. A2007592
文摘Very little is known about visual functional recovery following long-term naltrexone administration in opioid-dependent patients. In the present study, a portable event-related potential （ERP） working system was utilized to collect and record ERP in opioid-dependent patients and normal controls in visual half-field testing. In addition, the influence of long-term sustained naltrexone release on the visual nervous system was observed in opioid-dependent patients. Results revealed a significant main group effect in reaction time to visual signal stimulations. The reaction time of normal controls was shortest, but longest in opioid-dependent patients. The reaction time of long-term sustained naltrexone release group and compulsory detoxification group was similar to normal controls. A significant main group effect was also observed in P100 latency, and P100 latency in normal controls and the compulsory detoxification group was significantly decreased compared with the opioid-dependent patients. P100 amplitude at the Oz-electrode resulted in a significant main group effect. In particular, normal controls exhibited significant differences compared with long-term sustained release naltrexone and compulsory detoxification groups. These findings demonstrated that long-term sustained naltrexone release effectively ameliorated optic center function and improved visual sensitivity and reactions in opioid-dependent patients.
基金supported by the National Natural Science Foundation of China(NSFC)(Grant Nos.22373014 and 22371043)the Natural Science Foundation of Fujian Province(No.2022J06019)the Open Project Program of Wuhan National Laboratory for Optoelectronics(No.2020WNLOKF009).
文摘With the rapid development of white LEDs,the research of new and efficient white light emitting materials has attracted increasing attention.Zero dimensional(0D)organic–inorganic hybrid metal halide perovskites with superior luminescent property are promising candidates for LED application,due to their abundant and tailorable structure.Herein,[(CH_(3))_(3)S]_(2)SnCl_(6)・H_(2)O is synthesized as a host for dopant ions Bi^(3+)and Sb^(3+).The Sb^(3+)doped,or Bi^(3+)/Sb^(3+)co-doped,[(CH_(3))3S]_(2)SnCl_(6)・H_(2)O has a tunable optical emission spectrum by means of varying dopant ratio and excitation wavelength.As a result,we can achieve single-phase materials suitable for emission ranging from cold white light to warm white light.The intrinsic mechanism is examined in this work,to clarify the dopant effect on the optical properties.The high stability of title crystalline material,against water,oxygen and heat,makes it promising for further application.
基金Supported by National Natural Science Foundation of China(11475164,11475169,11675166)
文摘The sensitivity of the D^0-D^-0 mixing parameters x and y is estimated in the wrong-sign decay D^0→K^＋π^-π^0 by time-dependent amplitude analysis. The resolution of the D^0 lifetime is essential in time-dependent Dalitz analyses. The Belle II detector, which aims to collect a total integrated luminosity of 50 ab^-1 of data, has σ = 140 fs in Monte Carlo studies, a factor of two improvement over that of Belle and Ba Bar, so the produced Dalitz signal Monte Carlo samples are smeared with this resolution. Then a time-dependent Dalitz plot fitting is performed on these smeared samples, and the sensitivity of D^0-D^-0 mixing parameters are σx = 0.057% and σy = 0.049%. These are about an order of magnitude improvement on current experimental results, without considering background effects.
基金National Natural Science Foundation of China(No.52164044)the Natural Science Foundation of Guizhou Province of China(No.2022[053])+1 种基金the Talent growth plan of Guizhou education department of China(No.[2022]137)the Plan of Key Laboratory of Advanced Manufacturing Technology of the Ministry of Education of Guizhou University,China(No.GZUAMT2021KF[12]).
文摘To improve the yield strength of metallic materials at low temperatures,a strategy of combining the calculation of phase diagrams(CALPHAD)technique with the overall valence electron concentration(OVEC)principle is applied,and a Ni_(2)CoCrNb_(0.2)medium-entropy alloy(MEA)with D022 superlattice(noted as theγ″phase)is designed.Bulk MEA samples without defects were successfully fabricated using laser additive manufacturing(AM),followed by solution treatment at 1200℃for 1 h and then aging at 650℃for 120 h.The nanoscaleγ″phase precipitated.The tensile results indicated that the MEA had superior yield strengths of∼1180 MPa and∼1320 MPa and tensile strengths of∼1335 MPa and∼1552 MPa at 293 K and 77 K,respectively.The yield strength obtained was superior to that of currently reported medium/high-entropy alloys and typical advanced cryogenic steel.The mechanical properties of the Ni_(2)CoCrNb_(0.2)MEA demonstrated a strong temperature dependence,and the increased yield strength was mainly attributed to the increase in lattice friction stress at low temperatures.This research provides a new strategy for producing materials with ultrastrong cryogenic yield strengths by AM.
基金Natural Science Foundation of Henan Province( 994 0 51 2 0 0 )
文摘The system which consists of a reliable machine, an unreliable machine and a storage buffer with infinite many workpieces has been studied. The existence of a unique positive time-dependent solution of the model corresponding to the system has been obtained by using C 0-semigroup theory of linear operators in functional analysis.
