Study and Measurement of Glidarc Driven by Magnetic Field

Non-thermal plasma at atmosphere was generated through glidarc discharge driven by magnetic field and observed by using a high speed charge coupled device （CCD） and photo multiplier tube （PMT）. The arc diameter projecting in the direction of arc motion （front-viewed diameter） and the diameter projecting in the perpendicular direction of arc motion （side-viewed diameter） were measured. The effect of both the arc current and the magnetic field was analysed. The front-viewed diameter was compared with the side-viewed one. Simultaneously the electricfield intensity was measured directly and analysed by considering the effect of the external magnetic field and arc current.

Targeted therapeutic effects of oral magnetically driven pectin nanoparticles containing chlorogenic acid on colon cancer

Oral colonic nano-drug delivery system has attracted growing attention in treating colon cancer for their excellent characteristics.However,the unique and complex structure of the gastrointestinal tract is still an obstacle to the safe delivery of drugs targeting sites in colon tumors.Here,we designed magnetically driven dual-targeted oral colonic nanoparticles loaded with chlorogenic acid using pectin and oleic acid-modified iron oxide(Fe3O4@OA).Specific degradation of pectin by pectinase produced by colonic flora and magnetic fields applied to the colon confers specific targeting of nanoparticles to the colon.In order to overcome the challenge of preparing magnetically driven nanoparticles with small and homogeneous particle sizes by a single conventional method,we developed the combined ultrasound-emulsification technique.The average particle size of the prepared nanoparticles was 81.04±1.02 nm,which showed good drug release in the simulated colonic environment.In vitro anticancer studies,the drug-loaded nanoparticles possess an obvious toxicity and apoptosis-inducing ability against cancer cells.Meanwhile,the hemolysis results demonstrated the safety of the nanoplatform(PET/CGA/Fe_(3)O_(4)@OA).This work holds broad prospects as a new treatment modality for colon cancer.

Mathematical Modeling of ESR Process for Hollow Ingot with Current Supplying Mould

With ificreasing demand for large cylindrical forgings, a new technology--electroslag remelting （ESR） for direct manufacture of hollow ingots rather than solid ingots has been developed. The main features of the process include a T-shaped current supplying mould （CSM）, double power supply, an ingot withdrawing system, a metal level automatic control system based on a level sensor using the electromagnetic eddy current method, and the exchange of a consumable multi-electrode. ANSYS software was used to calculate the fluid flow and heat transfer in the slag bath 1 and metal pool of this ESR hollow ingot process with its T-shaped CSM. The mathematmal model was Verified by measuring the geometry of the liquid metal pool as observed in the macrostructure of 4650 mm （external diameter）/ 4450 mm （internal diameter） hollow ingots by sulphur print method： the. observed shape and depth of the s!ag bath were consistent with the simulated results. Simulation of the ESR process can improve understanding of the process and allow better operating parameters to be selected.