An integrated production planning and control model based on MRPⅡand JIT is put forward through analyzing the characteristics of magnetic materials manufacturing companies. Master Production Schedule with limited cap...An integrated production planning and control model based on MRPⅡand JIT is put forward through analyzing the characteristics of magnetic materials manufacturing companies. Master Production Schedule with limited capacity and operational plan in workshop level based on the basic data of flow chart are formulated by this model which applied JIT idea and based on customer order demand. Push production is adapted during execution phase combined with process flow cards. The model is helpful to reduce inventory,keep certain flexbility of production and improve continuity and equilibrium of manufacturing process.展开更多
嵌合抗原受体T细胞(chimeric antigen receptor T cell,CAR-T)治疗产品的上市为恶性肿瘤治疗提供了新手段。能否持续生产高质量的CAR-T治疗产品对CAR-T治疗的成功至关重要。本文论述CAR-T治疗产品生产工艺控制及质量管理中应予以特别关...嵌合抗原受体T细胞(chimeric antigen receptor T cell,CAR-T)治疗产品的上市为恶性肿瘤治疗提供了新手段。能否持续生产高质量的CAR-T治疗产品对CAR-T治疗的成功至关重要。本文论述CAR-T治疗产品生产工艺控制及质量管理中应予以特别关注的几个要点,以期为该类产品质量的持续改进和监管机构的监管提供参考。展开更多
基金supported by Ministry of Education Social Science and Humanities Fund(12YJA630187)SHANNXI Social Science Fund(10Q067)High Education Research Fund of Northwestern Polytechnical University(2014)
文摘An integrated production planning and control model based on MRPⅡand JIT is put forward through analyzing the characteristics of magnetic materials manufacturing companies. Master Production Schedule with limited capacity and operational plan in workshop level based on the basic data of flow chart are formulated by this model which applied JIT idea and based on customer order demand. Push production is adapted during execution phase combined with process flow cards. The model is helpful to reduce inventory,keep certain flexbility of production and improve continuity and equilibrium of manufacturing process.
文摘嵌合抗原受体T细胞(chimeric antigen receptor T cell,CAR-T)治疗产品的上市为恶性肿瘤治疗提供了新手段。能否持续生产高质量的CAR-T治疗产品对CAR-T治疗的成功至关重要。本文论述CAR-T治疗产品生产工艺控制及质量管理中应予以特别关注的几个要点,以期为该类产品质量的持续改进和监管机构的监管提供参考。